Ancient Indian System Of Medicine Research Articles

EXPLORING AYURVEDIC APPROACHES TO LOW BACK PAIN: A COMPREHENSIVE REVIEW

Introduction:Low back pain (LBP) is a common musculoskeletal disorder affecting individuals worldwide, causing significant disability and healthcare burden. While conventional treatments focus on symptomatic relief, Ayurveda, the ancient Indian system of medicine, offers a holistic approach that addresses the root cause of LBP. This comprehensive review aims to explore Ayurvedic perspectives, diagnostic methods, therapeutic interventions, and herbal formulations for managing LBP. Ayurvedic Perspective:Ayurveda views LBP as a manifestation of imbalances in the Tridosha (Vata, Pitta, and Kapha) and the Saptadhatus (seven body tissues). Vata dosha vitiation is predominantly implicated in LBP, leading to symptoms such as stiffness, spasms, and radiating pain. Pitta and Kapha imbalances may exacerbate inflammation and structural degeneration, respectively. Ayurvedic diagnosis of LBP involves assessing the individuals Prakriti (constitutional type), Vikriti (current imbalance), Agni (digestive fire), and Srotas (channels of circulation). Diagnostic Methods:Ayurvedic physicians employ a combination of clinical examination, palpation, and pulse diagnosis (Nadi Pariksha) to assess the underlying doshic imbalances and identify the specific etiology of LBP. Various factors such as lifestyle habits, occupation, dietary patterns, and psychological stressors are taken into account during the assessment. Therapeutic Interventions:Ayurvedic management of LBP is multifaceted, aiming to alleviate pain, reduce inflammation, restore musculoskeletal integrity, and prevent recurrence. Therapeutic interventions include: Panchakarma: Detoxification therapies such as Basti (medicated enema), Abhyanga (oil massage), and Swedana (herbal steam therapy) are utilized to eliminate ama (toxins) and pacify aggravated doshas. Ayurvedic Medications: Herbal formulations containing anti-inflammatory, analgesic, and muscle-relaxant herbs like Ashwagandha (Withania somnifera), Guggulu (Commiphora wightii), and Shallaki (Boswellia serrata) are prescribed to manage pain and inflammation. Yoga and Pranayama: Specific yoga asanas (postures) and pranayama (breathing exercises) are recommended to improve flexibility, strengthen the back muscles, and enhance prana (vital energy) flow to the affected area. Dietary Modifications: Dietary recommendations include consuming warm, light, and easily digestible foods, emphasizing anti-inflammatory spices like turmeric, ginger, and cinnamon, and avoiding cold, heavy, and processed foods that may aggravate Vata dosha. Lifestyle Management: Adopting a balanced daily routine (Dinacharya), practicing stress-reduction techniques such as meditation and mindfulness, and maintaining proper posture and ergonomics are crucial for long-term management of LBP. Clinical Evidence:Several clinical studies have investigated the efficacy of Ayurvedic interventions in LBP management. A randomized controlled trial comparing Ayurvedic treatment with conventional therapy demonstrated significant improvements in pain relief, functional disability, and quality of life among participants receiving Ayurvedic intervention. Furthermore, observational studies have reported favorable outcomes with Panchakarma therapies and herbal formulations in reducing pain intensity and enhancing mobility in patients with chronic LBP. Safety and Considerations:While Ayurvedic interventions are generally considered safe when administered under the guidance of a qualified practitioner, certain precautions should be observed. Individualized treatment plans based on the patients constitution, doshic imbalance, and overall health status are essential to optimize therapeutic outcomes and minimize potential adverse effects. Additionally, close monitoring and periodic reassessment are necessary to track progress and adjust treatment as needed. Conclusion:Ayurveda offers a holistic and individualized approach to managing low back pain, addressing not only the symptoms but also the underlying imbalances contributing to the condition. By incorporating Panchakarma therapies, herbal formulations, dietary modifications, and lifestyle interventions, Ayurvedic treatment aims to restore harmony within the body, promote self-healing, and prevent recurrence of LBP. Further research and collaboration between Ayurvedic and conventional healthcare systems are warranted to validate the efficacy and safety of Ayurvedic interventions and enhance their integration into mainstream healthcare for comprehensive LBP management.

Significance of Ayurvedic Cosmetology in Contemporary Context: A Critical Review

Introduction: The human skin, the body’s largest organ, serves vital functions in physical protection and health reflection. However, modern lifestyle factors often compromise skin health, leading individuals to rely on cosmetic products that may exacerbate damage. Materials and Methods: Ayurveda, an ancient Indian medicinal system, offers holistic approaches to skin care and beauty maintenance, emphasizing internal and external well-being. Ayurvedic texts detail various herbal formulations and practices for skin care, including external applications like Lepa and internal remedies such as Vayasthapan Mahakashaya and Varnya Mahakashaya. Results: Ayurveda addresses a broad spectrum of dermatological concerns, including skin and hair care, fairness, stretch mark elimination, foot care, hair coloring, removal, acne treatment, scar reduction, and dandruff management. These treatments are known for their safety, affordability, and high efficacy. Discussion: This review explores Ayurvedic principles and practices relevant to contemporary dermatological challenges, highlighting its effectiveness in skin care and beauty maintenance. Conclusion: Ayurveda presents promising solutions for modern skin care dilemmas, offering safe, affordable, and effective alternatives to conventional cosmetic products.

Ayurvedic Insights on Improving Poor Sleep Quality

Sleep – this natural urge is so essential phenomenon of life that engages our one third of life-span, still indulging in being slept is mystery to everyone. At one side adequate sleep quality imparts fair concentration, emotional, cognitive motivational harmony inside body’s mind, soul and consciousness. Contrary to which inadequate sleep or poor sleep quality leads to tiredness, lack of focus, exhaustion, a low pain tolerance, anxiety, irritational thoughts, hallucinations, loss of appetite, constipation and many more. Sleep has a positive impact over digestion, metabolism, nourishment and health. It is irresistible, irreplaceable and unique boon for us, which is pillar of our life. The natural cycle of sleep and awakening is depending on Awastha of Sharir Dosha, Kaal Dosha, and few more factors as depicted in Ayurveda texts. So, the quality of sleep depends on these factors. If there is Kshaya of Kapha, or Vriddhi of Vata and Pitta, then the quality of sleep disturbs. In the realm of holistic well-being, Ayurveda, the ancient Indian system of medicine, offers profound insights into optimizing sleep quality. Through personalized approaches, Ayurvedic remedies like herbal formulations, lifestyle modifications, and relaxation techniques aim to rebalance Doshas and promote restful sleep. Integrating practices such as meditation, gentle yoga, and consistent sleep routines can pacify Vata and Pitta Dosha, calm the mind, and induce relaxation, fostering deeper and more rejuvenating sleep. Ayurveda's holistic perspective provides a natural and sustainable pathway to address poor sleep quality and promote overall well-being. The present paper is here to discuss in detail about Sukh Nidra.

Extraction and Analytical Study of Semecarpus Anacardium L. Seed Oil

Bhallataka, also known as the marking nut or dhobi nut, is a potent ingredient in Ayurvedic medicine. Despite its irritant nature, it's been used for centuries to treat a myriad of diseases. Its oil, extracted using the Patala Yantra, is a key formulation in Ayurvedic pharmaceutics. Ayurveda, the ancient Indian system of medicine, is gaining global recognition for its holistic and natural approach to health. A significant part of Ayurvedic treatments are plant-based, ranging from raw plant materials to refined extracts. One such plant is Semecarpus anacardium Linn, the botanical source of Bhallataka. The plant is being traditionally used by the ancient healers in clinical practice. Apart from the clinical uses the plant was also used for marking clothes, as hair dyes and in many non-therapeutic uses as well. Bhallataka is a plant which holds much significance in Siddha and Unani system of medicine. Various studies have been conducted to understand its physical and chemical nature of the plant, in order to understand its use in therapeutic purposes. Chemical and phytochemical analysis of Bhallataka nut reveals a treasure trove of bioactive compounds- biflavonoids, phenolic compounds, bhilawanols, minerals, vitamins, and amino acids. These compounds make Bhallataka effective against various diseases like arthritis, tumors, and infections. The oil of Bhallataka, extracted using the Patala Yantra method, is particularly noteworthy. This oil is an integral part of Ayurvedic pharmaceutics, and its application is referenced in various ancient texts.

Cell line studies in Ayurveda: Bridging ancient wisdom and modern science

Ayurveda, an ancient Indian system of medicine, offers holistic solutions to modern health challenges by addressing the root causes of illness. In recent years, there has been a growing interest in integrating Ayurveda with modern scientific approaches through interdisciplinary research to explore synergies and uncover novel insights for healthcare advancements. Cell line studies are emerging as a pivotal tool in this effort. These studies facilitate the exploration of the molecular mechanisms underlying Ayurvedic principles and formulations, offering valuable insights into their therapeutic efficacy. This review article evaluates the role of cell line studies in bridging the gap between ancient Ayurvedic wisdom and modern scientific understanding. It provides an overview of existing research on cell line studies of Ayurvedic medicines, exploring their effectiveness, identifying key herbs and formulations studied, discussing clinical and pharmacological findings, addressing challenges and future directions, and emphasizing the importance of scientific validation when integrating Ayurveda into conventional healthcare.

Vanilla: A Review of Powerful Herb with Ayurvedic Medicinal Properties

Vanilla, derived from the beans of the Vanilla planifolia orchid, is a globally cherished spice known for its sweet aroma and flavor. Beyond its culinary applications, this review delves into the Ayurvedic medicinal properties of vanilla, unraveling its potential as a powerful herb in traditional medicine. Ayurveda, the ancient Indian system of medicine, recognizes vanilla for its diverse therapeutic attributes. The active compounds in vanilla, such as vanillin, contribute to its antioxidant and anti-inflammatory properties. These qualities align with Ayurvedic principles, emphasizing the balance of bodily functions and prevention of diseases. Vanilla has been historically employed to alleviate digestive disorders, respiratory ailments and stress-related conditions. Ayurvedic practitioners harness its calming effects on the nervous system, promoting mental well-being. Moreover, vanilla is explored for its potential antimicrobial properties, adding a layer of significance in the context of Ayurveda where natural remedies play a pivotal role. The herb's use in Ayurvedic formulations underscores its adaptability across diverse health concerns. This review consolidates current scientific research alongside traditional Ayurvedic wisdom to provide a comprehensive understanding of vanilla's medicinal potential. As consumer interest in holistic well-being grows, the integration of vanilla into Ayurvedic practices not only expands its applications but also exemplifies the synergy between traditional and contemporary approaches to health. Unveiling the multifaceted nature of vanilla as a potent herb, this exploration encourages further investigations and applications of its Ayurvedic medicinal properties in modern healthcare.

THE HONEY TRAP: IS HEATED HONEY REALLY THAT BAD?

Introduction- The consumption of honey mixed with hot water or heated honey has been a practice. However, concerns have arisen regarding the potential harmful effects of this practice, both according to Ayurvedic principles and scientific evidence. Ayurveda, the ancient Indian system of medicine, emphasizes the importance of consuming honey (Madhu) in its raw, unheated form. Acharyas have mentioned that heating honey alters its chemical properties, transforming it into a substance that is visha (poison) to the body. A dooshi visha, or unnatural substance, is any substance that can disrupt the balance of the doshas and contribute to disease. When honey is heated, it undergoes a chemical transformation, leading to the formation of a compound called 5-hydroxymethylfurfural (HMF). HMF can be considered a dooshi visha in Ayurveda due to its potential to disrupt the delicate balance of the doshas. According to Ayurvedic principles, the doshas are in a constant state of flux, and their balance is essential for maintaining health. HMF, with its propensity to alter the doshas, can throw this equilibrium off, leading to various health problems. Aims and Objectives: To understand the effect of consuming heated honey (Madhu) on humans. Materials and Methods: Modern textbooks and Authenticated sources were scrutinized for the understanding of properties, chemical composition of honey and ayurvedic textbooks were scrutinized for further understanding. Conclusion and Discussion: Based on both Ayurvedic principles and scientific evidence, it is advisable to consume honey in its raw, unheated form to reap its full health benefits and minimize potential risks. While honey mixed with hot water or heated honey may be part of practices, these methods may compromise the beneficial properties of honey and pose potential health concerns. KEY WORDS- Honey, Madhu, Visha, dooshi visha, HMF.

Development of Foetal Body Parts as per Garbhaavakraanti Shaareera - An Ayurvedic Perspective

The conception and development of a healthy offspring have been a paramount concern for humanity throughout history. This concern is deeply rooted in various cultures and traditions, and Ayurveda, an ancient Indian system of medicine, offers a holistic perspective on factors that influence the growth and development of a fetus. Ayurveda underscores several critical factors to ensure the birth of a normal and healthy progeny. These factors include "Garbha Saamagri," which pertains to the quality of reproductive materials, emphasizing the significance of the parents' health at the time of conception. "Daurhruda" relates to the timing and season of conception, asserting that environmental factors play a role in the child's health. The "Pitrujadi Six Factors" encompass inherited attributes from both parents, stressing the importance of genetic compatibility between partners. Additionally, Ayurveda places a strong emphasis on the lifestyle and nutrition of the pregnant woman, her emotional well-being, and the regimen during her menstrual cycle. All these factors are believed to influence the child's constitution and overall health. "Svabhava" considers the inherent nature and constitution of both parents, which can affect the physical and mental attributes of the child. It is important to note that Ayurveda offers a holistic and ancient perspective on these factors. In conclusion, Ayurveda provides a comprehensive framework for understanding the factors that influence fetal growth and development.

Sattvavajaya Chikitsa: Need of Today’s Era

Speed, accuracy and over ambitiousness are the prime demands of today’s metaphysical society. People can’t even pay attention to their physical and mental health. Irregular food habits, suppression of natural urges, insomnia are becoming the part and parcel of today’s life, giving rise to psychosomatic disorders. Ayurveda, the ancient system of Indian medicine evolved through millennium contains clear potentials of the modern understanding of natural science. Inspire of its historically inevitable beginnings, the science took in the ancient period itself the momentous step from the magic-religious therapeutics to rational therapeutics i.e., in the terminology of physicians themselves from Daivavyapashraya Chikitsa to Sattvavajaya Chikitsa. Ayurveda has considered the mental and physical diseases as two separate specialized subjects in certain contexts. However, no line of demarcation has been drawn between the physical and mental diseases and a flexible psychosomatic approach has been put forward. Ayurveda emphasizes its treatment modalities into three Chikitsa viz., Sattvavajaya Chikitsa, Yuktivyapashraya and Daivavyapashraya Chikitsa. Sattvavajaya is the mental restraint, or a “mind control” as referred by Charaka, is achieved through “spiritual knowledge, philosophy, fortitude, remembrance, and concentration. Health regimens as (Swasthvritta), good conduct (Sadvritta), and yoga acts as a traditional mental health promoting practices.

A Comprehensive Analysis of Noise-Induced Hearing Loss and Its Ayurvedic Insight

Noise-induced hearing loss (NIHL) is a growing global health concern, primarily attributed to our increasingly noisy environments. This comprehensive analysis delves into the multifaceted aspects of NIHL while exploring potential insights from Ayurveda, an ancient Indian system of medicine. NIHL results from prolonged exposure to loud noise levels, causing damage to the delicate structures of the inner ear. It is a gradual and irreversible condition that affects millions of people worldwide, impacting their quality of life and overall health. Traditional approaches to NIHL management primarily focus on hearing aids and protective measures. However, this analysis seeks to integrate Ayurvedic principles and treatments to offer a holistic perspective on NIHL prevention and management. Ayurveda, with its holistic approach to health, considers the interplay of physical, mental, and environmental factors. In Ayurveda, hearing loss can be linked to imbalances in the doshas (Vata, Pitta, and Kapha) and the accumulation of toxins in the body. By addressing these imbalances through dietary modifications, lifestyle changes, and herbal remedies, Ayurveda may offer valuable insights into preventing and managing NIHL. The analysis highlights the importance of noise awareness, emphasizing the need for public health campaigns and workplace regulations to reduce noise exposure. Additionally, it explores Ayurvedic herbs and therapies known for their potential in mitigating the effects of NIHL, such as Ashwagandha (Withania somnifera) and Panchakarma detoxification procedures. Furthermore, the study discusses the role of yoga and meditation in stress management, as chronic stress can exacerbate NIHL. Ayurvedic practices like Pranayama (breathing exercises) and Shirodhara (oil therapy for the head) may promote relaxation and reduce stress, contributing to overall hearing health. In conclusion, this analysis offers a comprehensive overview of NIHL, including its causes, symptoms, and conventional management strategies. By incorporating Ayurvedic insights, we explore a holistic approach to NIHL prevention and management, acknowledging the potential benefits of Ayurveda in promoting hearing health. Further research and collaboration between traditional and modern healthcare systems are essential to harness the full potential of Ayurveda in addressing the global issue of NIHL.

The Healing Potential of Nidra in Ayurvedic Medicine: A Comprehensive Overview

Nidra is considered an essential aspect of maintaining overall health and well-being according to Ayurveda, the ancient Indian system of medicine. The article delves into the Ayurvedic principles and philosophies that underpin the significance of Nidra in promoting physical, mental, and emotional healing. Ayurvedic understanding of sleep and its relationship with the body's Doshas (energetic forces) - Vata, Pitta, and Kapha. It highlights how an imbalance in these Doshas can disrupt the quality and duration of sleep, leading to various health issues. Additionally, the article explores the concept of "Sukha Nidra" (restful sleep) as an integral part of Ayurvedic daily routines (dinacharya) and its impact on overall vitality. Therapeutic benefits of Nidra in addressing specific health concerns, such as stress, anxiety, insomnia, and fatigue. It explores the role of Nidra in promoting cellular rejuvenation, hormonal balance, and the restoration of the body's natural healing mechanisms. Ayurvedic practices, such as the use of herbs, oils, and lifestyle modifications, to enhance the quality of sleep are also discussed. Ayurvedic techniques and practices that can optimize Nidra and facilitate deeper, more restorative sleep. These include meditation, Pranayama (breathing exercises), yoga asanas (postures), and the adoption of a balanced Ayurvedic diet. The article emphasizes the holistic nature of Nidra, highlighting its ability to address imbalances on physical, mental, and spiritual levels. Overall, this comprehensive overview aims to shed light on the healing potential of Nidra, providing valuable insights for individuals seeking natural and holistic approaches to improve sleep quality and overall well-being.

Cognitive Psychology: As essential & integrated part of medical education w.s.r. to Yukti Pramana in Ayurveda

Growth of any knowledge base depends on a dynamic continuum of a tripod of creating new knowledge through research, effective transfer of knowledge through proactive education and utilization of the knowledge with good professional practice. A set of knowledge system is likely to be relative to time & place setting which facilitates its need based development. But though Ayurvedic education system is one of the recognized age old education systems but still neither developed nor advanced alike other education system across the globe. Due to lack of maintenance of such dynamic continuum in current education system of ancient system of Indian medicine, the knowledge bases of Ayurveda becomes stagnant, static & gradually pass into merely history &may not remain dynamic & useful. Need of dynamism and activism through incorporation of cognitive psychology in education curriculum and enhancement of reasoning skill followed by critical thinking in the mind of medical professionals is quite necessary in the field of Ayurveda to make it up to date and develop it further in tune with the changing needs of the society today. Keeping this in view an effort has been made by the author to explore the concept of Yukti as key element of cognitive psychology make its relevant application in the field of current teaching & education and practice of Ayurved worldwide.

UNLOCKING THE ANCIENT WISDOM: AYURVEDIC SECRETS FOR MANAGING SANDHI VATA (OSTEOARTHRITIS)

Discover the fascinating world of Ayurveda as we delve into its age-old wisdom for managing (Sandhivata), commonly known as osteoarthritis. This ancient Indian system of medicine offers holistic approaches to address the root cause of joint degeneration and promote overall well-being. Through a careful balance of Vata Dosha, detoxification therapies, herbal remedies, yoga, and lifestyle modifications, Ayurveda provides a comprehensive and natural way to alleviate joint pain, reduce inflammation, and enhance joint health. Join us on a journey to unlock the hidden secrets of Ayurveda and uncover its potential in managing Sandhivata, offering a ray of hope to those seeking effective and sustainable solutions for this debilitating condition.

AYURVEDIC APPROACH TO GUILLAIN-BARRÉ SYNDROME: RESTORING BALANCE AND STRENGTHENING THE NERVOUS SYSTEM

Guillain-Barré Syndrome (GBS) is a neurological disorder characterized by muscle weakness and paralysis caused by the immune system attacking the peripheral nerves. While conventional medical treatments are essential for managing GBS, Ayurveda, the ancient Indian system of medicine, offers holistic approaches to complement conventional therapies. This article explores Ayurvedic perspectives on GBS and presents a range of Ayurvedic treatment strategies, including Panchakarma therapy, herbal medicines, diet and lifestyle modifications, Ayurvedic medicinal oils, and stress management techniques. These approaches aim to restore balance to the Vata dosha, rejuvenate the nervous system, and support overall well-being. While Ayurveda does not claim to provide a cure for GBS, integrating Ayurvedic principles with conventional treatments can potentially enhance recovery and improve symptom management. A collaborative approach between Ayurvedic practitioners and medical professionals is crucial for developing personalized and effective treatment plans for individuals with GBS.

KERALIYA CONVENTIONAL TREATMENT MODALITIES AND SANSARJANA KARMA FOR PEDIATRICS; SHORT REVIEW

Ayurveda, an ancient Indian System of Medicine, has been in mode from times immemorial to impart natural healing for various ailments. This system is believed to be quite safe and free from side effects as it is more close to nature. The development of Ayurveda in Kerala is particularly noted for its origins in non-brahminical traditions even before the entry of classical Ayurveda. Selected few brahmin households, named Ashtavaidyas, carried forward Ayurvedic tradition by practicing it as a health care service as well as by teaching its principles in the unique Gurukula tradition. The traditional practitioners of Ayurveda considered Ashtangahridaya as a primary text. .Ayurveda physicians in the state developed simplified procedures of therapies of Kerala without violating the fundamentals of Ayurveda. Sirodhara, Pizhichil, Chauthi thirumal, Navarakizhi, Thalapothichil, Pachakizhi and Podikizhi are some of the Kerala special Ayurvedic procedures developed in Kerala. After samshodhana, the expulsion of doshas and mala from body impression of Agni converted into manda(mildest form) type1, hence cannot tolerate the caliber of food articles. This procedure helps to boost the agni gradually and digestive power turn into more powerful and stable by tiny fire with the help of vayu (air) 2 The disease child should take complete rest for an equal period of time for which he has undergone the therapeutic procedure. Samsarjana krama is done as the disease child requires to regain the strength of dhatus and to come to normalcy. KEY WORDS – Agni, Dhathu, Keraliya treatments, Sansarjana Karma, samshodhana

A Critical Review on Mooshika Dansha[Rat Poisoning] in Agad Tantra

Ayurveda is an ancient Indian system of medicine having eight important branches. Agadtantra is among oneof them which deals with Visha (poison) and its toxicological conditions and their management. AcharyaSusruta in Kalpa Sthana of Susruta Samhita, and Acharya Vagbhata in Uttaratantra of Ashtanga Hridaya,moreover in other classics and regional texts have recited concerning the origin of Visha and mooshikaVisha.There are eighteen types of Mooshika, signs and symptoms of their bite and its treatment is described bySushrutaacharya and Vaagbhataacharya. There are five modes of spread of Mooshika (rat) VISHA that areShukra[Semen], Purisha[Feaces], Mutra[Urine],Nakh [scratches by nails] and Dant[ bites with teeth ofMooshika] are poisonous. In case of Mooshika Visha, Dansha sthan [bite site] should be cauterized andRaktamokshana by blood letting should be done. After this various drugs paste should be applied on bite site.Various putrifictory therapies should be givene.g.Lepan, Vamana(Vomiting), Virechana(Purgation) Nasya(Nasalmedication), Anjana (Collyrium) etc. Various Kalpanas [drug preparations] like Sanskarit Ghrita[medicatedghee], Kwath [decoctions], Kalka[paste of drugs], Swarasa [juice of drugs] aremetionedwheresource of infection is rat treatment of Mooshika Visha can be given.

Role of Kapha Dosha in Disease Pathogenesis and Its Prevention

According to Ayurveda, an ancient Indian system of medicine, Kapha dosha is one of the three fundamental biological energies or "doshas" that govern our physical and mental functions. Kapha is associated with the earth and water elements, and it provides structure and stability to the body. An imbalance in kapha dosha is believed to contribute to the pathogenesis of various diseases. When kapha dosha accumulates in excess or becomes aggravated in the body, it can lead to a blockage of the channels of circulation, digestion, and elimination, which can cause various health problems. Overall, an excess or imbalance of kapha dosha can contribute to the pathogenesis of various diseases through its effects on mucus, digestion, metabolism, and energy levels. Therefore, it is important to maintain a healthy balance of kapha dosha through a balanced lifestyle, including a healthy diet, regular exercise, and stress management techniques. In this article an effort has been made to understand the complete classical knowledge of kapha dosha and its importance in disease pathogenesis and in treatment.

“Studies on Preparation of Value-Added Amla Squash with Herbs”

Squash is a concentrate drink beverage, which must be diluted with water before consumption. Herbal extracts are added in the fruit extract as to enhance the sensory and therapeutic value ofthe product. Amla is one of the precious gifts of nature to mankind. Amla, has been used in Ayurveda, the ancient Indian system of medicine since ancient times. The benefits of Amla, Ginger, Tulsi and Mint which is having antibacterial, anticarcinogenic, antiemetic, antiviral, antitumor, anti-cardiotoxic properties which officious for treatment of diabetes, cancer arthrosclerosis, liver etc. Herbs have medicinal, aromatic, phototherapeutic properties. It is richsource of micro nutrient and phenolic compounds. The amla with herbs squash are taken in daily diet then it’s helpful to remove the toxic elements from the body Utilization of the amla with herbs in the diet or by incorporation and optimizing their use in fruit beverages, an individual will get all the benefits related to health and also reduces the risk of serious diseases like cancer.

Deciphering the mechanism of Tinospora cordifolia extract on Th17 cells through in-depth transcriptomic profiling and in silico analysis.

Naive CD4+ T cells differentiate into effector (Th1, Th2, Th17) cells and immunosuppressive (Treg) cells upon antigenic stimulation in the presence of a specific cytokine milieu. The T cell in vitro culture system provides a very efficient model to study compounds' therapeutic activity and mechanism of action. Tinospora cordifolia (Willd.) Hook.f. & Thomson (Family. Menispermaceae) is one of the widely used drugs in Ayurveda (ancient Indian system of medicine) for various ailments such as inflammatory conditions, autoimmune disorders, and cancer as well as for promoting general health. In vitro and in vivo studies on immune cells comprising dendritic cells, macrophages, and B cells suggest its immune-modulating abilities. However, to date, the effect of T. cordifolia on individual purified and polarized T cell subsets has not been studied. Studying drug effects on T cell subsets is needed to understand their immunomodulatory mechanism and to develop treatments for diseases linked with T cell abnormalities. In this study, we examined the immunomodulatory activity of T. cordifolia on primary CD4+ T cells, i.e., Th1, Th17, and iTreg cells. An aqueous extract of T. cordifolia was non-cytotoxic at concentrations below 1500µg/ml and moderately inhibited the proliferation of naive CD4+ T cells stimulated with anti-CD3ε and anti-CD28 for 96h. T. cordifolia treatment of naive CD4+ T cells differentiated under Th17-polarizing conditions exhibited reduced frequency of IL-17 producing cells with inhibition of differentiation and proliferation. For the first time, in-depth genome-wide expression profiling of T. cordifolia treated naive CD4+ T cells, polarized to Th17 cells, suggests the broad-spectrum activity of T. cordifolia. It shows inhibition of the cytokine-receptor signaling pathway, majorly via the JAK-STAT signaling pathway, subsequently causing inhibition of Th17 cell differentiation, proliferation, and effector function. Additionally, the molecular docking studies of the 69 metabolites of T. cordifolia further substantiate the inhibitory activity of T. cordifolia via the cytokine-receptor signaling pathway. Furthermore, in vitro polarized Th1 and iTreg cells treated with T. cordifolia extract also showed reduced IFN-γ production and FoxP3 expression, respectively. This study provides insight into the plausible mechanism/s of anti-inflammatory activity of T. cordifolia involving T cells, mainly effective in Th17-associated autoimmune and inflammatory diseases.

“Preparation of Sugar-Free Wheat through Ancient Indian Process” – An Analytical Study

Introduction: Wheat, a nutrient-dense cereal grass, has been eaten since the dawn of humanity. Various Ayurvedic literatures described its properties. They prescribed it for diabetes (Madhumeha), obesity (Sthaulya), hyperlipidemia (Medhaj and Kaphaj Rogas), and other diseases. Food preparation (Samskara) is highly valued in the Ancient System of Indian Medicine. It involves feeding ruminants (cows, horses, etc.) wheat and collecting the grains from their feces. It is believed that when grains pass through these ruminants' guts, they acquire beneficial properties that can be used to treat diseases such as diabetes. The current study involves feeding wheat grains (WGs) to cows and comparing the grains recovered from their excrement to conventional wheat that has not been subjected to this technique. Methods: Cows were fed with WGs. The grains were collected from cow dung. These grains were washed properly and shade dried. These grains were then subsequently tested for phytochemical analysis to compare the properties between unfed normal wheat and cow fed wheat. Results: Sugar levels in the cow fed partially digested wheat are below the detectable levels, and even the carbohydrates level is low as compared to normal unfed wheat. Conclusion: Sugar levels in the cow fed partially digested wheat are below the detectable levels, and even carbohydrates level is low while as compared to normal unfed wheat. Results synchronize to what has been mentioned in the Ancient Indian System of Medicine. This might be why it is advised for the management of Madhumeha diabetes mellitus.