The biosynthesis of the alkaloids ofAmmodendron karelinii Fisch. et Mey has been studied by feeding the plant with labelled [1,5-14C]cadaverine. It has been shown that cadaverine is a precursor of anagyrine, pachycarpine, ammodendrine, N-methylcytisine, and cytisine. Possible routes of interconversions have been considered by feeding the plant with the tritium-labelled [3H]pachycarpine, [3H]lupanine, [3H]anagyrine, and [3H]ammodendrine.