PurposeThis study aimed to investigate the usefulness of measuring biomechanical parameters using the Corvis ST to predict the occurrence of hypotony maculopathy and choroidal detachment (CD) following trabeculectomy or bleb needling revision with mitomycin C (MMC). DesingClinical cohort study MethodsThis study included 100 eyes of 100 patients who underwent trabeculectomy (88 eyes of 88 patients) or bleb needling (12 eyes of 12 patients) with MMC. A significant predictor of hypotony complications was identified from 1) operation (trabeculectomy or bleb needling), 2) age, 3) sex, 4) disease type (primary open angle glaucoma [POAG], exfoliation glaucoma [EG] or other), 5) lens status (phakia or pseudophakia), 6) preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), 7) preoperative central corneal thickness (CCT), 8) preoperative axial length (AL), 9) preoperative anterior chamber (AC) depth, 10) “Min IOP” (IOP value when hypotony complications occurred, otherwise the minimum IOP during 3 months from trabeculectomy or bleb needling), 11) preoperative corneal curvature, and 12- 24) 12 Corvis ST parameters using multivariate logistic regression. ResultsThere were 13 and 21 eyes developed hypotony maculopathy and CD, respectively. Male gender, greater preoperative GAT IOP and greater HC deflection Amplitude were significant predictors of the occurrence of hypotony maculopathy (p <0.05). On the other hand, shorter axial length, thinner CCT, greater preoperative GAT IOP and pseudophakia were significant predictors of the occurrence of CD (p <0.05). ConclusionsA careful attention should be paid to the occurrence of hypotony maculopathy with male gender and greater HC deflection Amplitude despite higher preoperative GAT IOP. Different risk factors were identified; shorter axial length, thinner CCT, greater preoperative GAT IOP and pseudophakia.