An analysis of numerous well data from the Karabagly and Kursangi monocline regions in Azerbaijan showed that the main reasons of natural curvature are structural and geological conditions of wells. In contrast to a number of fields where wells are naturally bent in only one direction under the combination of geological, technical and technological factors, there are three other directions in the areas of the Karabagly and Kursangi monocline. It is suggested that according to the proposed technology, drilling intervals are minimized by an assembly with a crooked sub, and the technical and economic parameters of drilling are improved. With an increase in the content of alkaline reagents in the drilling fluid, despite a significant decrease in the absolute value of fluid loss, the likelihood of complications increases. One of the main requirements for maintaining the integrity and stability of the wellbore is the prevention of filtration. This condition imposes a certain limitation on the amount of fluid loss in drilling fluids. In drilling practice, it is necessary to strive not only to minimize the fluid loss of flushing fluids, but also to the qualitative and quantitative evaluate various additives that slow down their physical and chemical impact on the rocks forming the walls of the well.