Background: Cardiovascular diseases (CVDs), primarily driven by hypertension (HTN), are a leading global health concern. While medication is commonly used to manage HTN, non-pharmacological approaches like ANB are gaining interest. ANB is a yogic breathing technique believed to modulate the autonomic nervous system, influencing heart rate and blood pressure. Methods: A systematic review adhering to PRISMA guidelines assessed studies published between 2015 and 2022 that investigated the effects of ANB on blood pressure in human subjects. Results: Six studies were included, with findings suggesting a potential benefit of ANB for reducing blood pressure. All studies, except one, reported significant reductions in systolic and/or diastolic blood pressure after ANB practice. Intervention duration varied across studies, ranging from single sessions to six weeks of daily practice. Some studies also observed a decrease in heart rate and improved vascular function following ANB. However, limitations exist: unclear control groups in some studies and varying intervention protocols. Discussion: Despite promising preliminary evidence, further well-designed, randomized controlled trials with larger sample sizes and standardized protocols are needed. Future research should compare ANB with sham interventions or standard medical management, and explore the underlying mechanisms of how ANB might influence blood pressure. Conclusion: While the current evidence requires further confirmation, ANB appears to be a safe and potentially beneficial non-pharmacological intervention for managing blood pressure, potentially as an adjunct to medication. Healthcare professionals may consider suggesting ANB to hypertensive patients, alongside lifestyle modifications and medication, but emphasize the importance of consulting a healthcare provider before starting any new practice.
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