P-nitrophenol (PNP) is a water contaminant with excessive harm to human body. It is usually converted into p-nitrophenol (PAP) by hydrogenation reduction. The silver-manganese and iron-based phosphate with an alluaudite like structure, namely Ag2Mn2Fe(PO4)3, was synthesized through solid-state reaction. The obtained data from X-ray diffraction was refined using the Le Bail method. Scanning electron microscopy provided a deep insight into the morphology of the elaborated powder, which was composed of homogeneous micrometric particles. The catalytic activity of Ag2Mn2Fe(PO4)3 was investigated through the reduction of p-nitrophenol (PNP) to p-aminophenol (PAP) using sodium borohydride NaBH4 as a reducing agent. The study reveals that Ag2Mn2Fe(PO4)3 is catalytically active for this reduction.