This study explores the challenges faced by airline cabin service from the perspectives of globalization and intercultural communication, as well as potential strategies to address these issues. The paper first reviews and analyzes the intercultural interaction problems that have emerged in airline cabin service, including language barriers, cultural clashes, and the misunderstandings and conflicts they bring. Subsequently, through field research and in-depth interviews, this article proposes and demonstrates a series of strategies to address these issues, including providing cultural adaptability training, enhancing cabin crew's language proficiency and intercultural communication skills, and improving the quality of service. Through the study and analysis of these strategies, this paper concludes that intercultural sensitivity and adaptability are crucial for improving the quality of airline cabin service and passenger satisfaction, providing theoretical basis and practical reference for airlines.