Air-supported membrane (ASM) envelopes offer an effective solution for creating large interior spaces for buildings with lower energy consumption and carbon emissions. However, there is little research on the thermal performance of ASM envelopes, particularly regarding the natural convection within the air interlayer and its impact on thermal resistance. To address this gap, this study developed a numerical model of ASM envelopes and validated it through experiments. Subsequently, a numerical investigation was conducted to analyze natural convection and thermal resistance while considering factors such as indoor-outdoor temperature difference, membrane emissivity and air interlayer thickness. Results indicated that with the emissivity increased from 0.2 to 1, the thermal resistance of the air interlayer and the envelope decreased by 32.35% and 9.13%, respectively. Besides, the thickness of air interlayer also had evident effect on thermal resistance. When it increased from 5 mm to 35 mm, the thermal resistance of the air interlayer and the envelope increased by 156.19% and 14.74%, and further results in the heat transfer decreased by 13.85%. However, the convective heat transfer would remain constant when the thickness exceeded 35 mm. This study provided valuable reference for optimizing the design of ASM envelopes and accurately calculating their thermal resistance.