Ain Shams University Research Articles

Factors influencing job performance of nurses in COVID-19 care: a study in Egypt.

Coronavirus disease (COVID-19) is an illness that has critical effects on public health and overall circumstances across the world. The performance of nurses represents the vital actions in providing care for COVID-19 patients. The aim of this study was to assess job performance and associated nurses, patients, and environmental-related factors among nurses providing care to COVID-19 patients in Egypt through the following: assessing the nurses' knowledge regarding care of COVID-19 patients; assessing the nurses' practice regarding care of COVID-19 patients; assessing different factors that affect different types of nurses' job performance; and assessing the factors associated with the job performance of nurses providing care to COVID-19 patients.Design A descriptive exploratory study was used to meet the aim of the study.Setting The study was conducted at Ain Shams University COVID-19 Hospital.Study subjects A convenient sample of all 52 available nurses working at Ain Shams University COVID-19 Hospital. Data collection tools: The data was collected using a self-administered questionnaire. It consisted of the following: A. Self-administered nurses' questionnaire: Part I: Demographic characteristics of nurses. Part II: Nurses knowledge assessment. Part III: Factors associated with nurses' job performance. B. Narses's practice observational checklist. Results: The mean age (mean ± SD) of the study population was 40.59 ± 6.90. As regards their years of experience working as nurses, only 32.7% of them have more than ten years of experience. In relation to the total satisfactory level of knowledge about coronavirus, the study reveals that 55.8% of the nurses have unsatisfactory knowledge regarding coronavirus, There is a highly significant relationship between level of practice and years of experience (p-value < 0.001**), while there is a significant relationship between level of practice and educational level and attending the training courses about caring for COVID-19 patients (P-value 0.033*, P-value 0.025*), respectively.Conclusion The study concluded that most of the studied nurses had unsatisfactory knowledge, and more than half had incompetent practice scores about nursing care practices for patients with COVID-19. There was a positive linear correlation between the nurses' knowledge and practice. The factors affecting their performance in caring for patients with COVID-19, lack of cooperation between nurses and patients, lack of supplies and equipment during care were the most frequently reported factors, as were an unequal nurse-patient ratio, many nursing tasks, and a lack of patients' knowledge.Recommendation The study recommends the importance of promoting the nursing care guidelines as a standard procedure in ICUs, and the nursing care guideline educational program for patients with COVID-19 should be scheduled regularly for nurses. Providing the hospitals with supplies to avoid the shortage's effect on nurses' performance.

Impact of L-carnitine supplementation on gastric emptying and bowel function in pediatric ketogenic diet therapy: a clinical trial

Ketogenic diet (KD) is an excess fat, enough protein, and minimal carbohydrate diet. The high fat content in KD lowers the oesophageal sphincter tone, slows gastric emptying, and decreases intestinal transit time. The primary aim of the current clinical trial was to study the effect of L-carnitine supplementation on gastric emptying in children with drug resistant epilepsy (DRE) on KD. Assessment of the protective effect of L-carnitine on bowel function and habits in those patients was a secondary aim. The current study recruited 30 patients aged 12 months to 18 years newly diagnosed with DRE assigned to start KD who were following up at the Pediatric Clinical Nutrition and Neurology Outpatient Clinics or were admitted due to DRE at the Pediatric Neurology Inpatient Department, Children’s Hospital, Ain Shams University (Egypt). Participants were assigned randomly into 2 arms; arm I: received KD with L-carnitine supplementation, arm II: received KD only. Patients were assessed at baseline and after 3 months of starting KD, the assessments of children included: 24-hour dietary recall, Chalfont Seizures Severity Scale, gastrointestinal symptoms score and Bristol stool chart, frequency of defecation per week, anthropometric measurements assessment, fasting serum lipid profile and measurement of the antral length by ultrasound. There was significant increase in antral length in the patients who received KD with L-carnitine supplementation compared to the non-supplemented group. The antral length showed a significant negative correlation with GI symptoms score in all cases and the L-carnitine supplemented group. It also showed a significant positive correlation with Bristol stool score in all patients and a significant positive correlation with stool frequency in the L-carnitine supplemented group only. L-carnitine supplementation to children with DRE on KD has a significant role in improving gastric motility and it increases the frequency of defecation. Further studies are recommended to explore additional benefits, meanwhile it is prudent to advise L-carnitine supplementation for such patients.

A suggested Frame work for the Impact of Integration between the Environmental Units at Egyptian Universities to Achieve the Sustainable Development (Comparative study between Ain Shams University and Cairo

A suggested Frame work for the Impact of Integration between the Environmental Units at Egyptian Universities to Achieve the Sustainable Development (Comparative study between Ain Shams University and Cairo

A study of some psychological variables as predictors of COVID-19 vaccination anxiety among Faculty Members of Ain Shams University

The study aimed to investigate the relative contribution of each of psychasthenia, psychological flexibility, suggestibility, and conspiracy beliefs in predicting the anxiety of vaccination with the anti COVID-19 vaccine among faculty members at Ain Shams University (ASU). Examining the difference in the sample’s scores on the vaccination anxiety scale and its sub-factors according to the variables (age—chronic diseases—academic specialization—previous infection with COVID-19—gender), the sample of the study included 139 faculty members at Ain Shams University aged ranged from 23 to 78 years, with a mean of 49.52 years, and a standard deviation of 13.29 years. The vaccination anxiety scale, psychasthenia scale, psychological flexibility scale, suggestibility scale, and conspiracy beliefs scale were used to collect data. The results revealed that the variables of suggestibility and conspiracy beliefs significantly contribute to predicting the vaccination anxiety among faculty members at Ain Shams University. There is a significant difference in the average scores on the vaccination anxiety scale according to age, with the difference in favor of the age group less than fifty years, as well as according to the presence/absence of a previous infection with COVID-19, with the vaccination anxiety being higher for those who were previously infected. There has been no observed significant difference according to the presence/absence of chronic diseases or academic specialization.

Egyptian patients with cleft lip: our experience with primary rhinoplasty

BackgroundControversy exists regarding the timing of rhinoplasty for patients with cleft lip as some surgeons shy away from primary correction for fear of causing harm to the growth of the nose and the maxilla.We present our favorable experience with primary rhinoplasty with repair of unilateral cleft lip in Ain Shams University plastic surgery department, providing insights into the specific management of patients of middle eastern descent.MethodsProspective study of 32 patients, ages 3 months- 1 year with unilateral CL presenting to Ain Shams University hospitals between January 2019 and July 2022. Primary rhinoplasty was performed at the time of lip repair. Lip repair was done by Tennison-Randall technique. Evaluation of results was done by expert analysis of photographs, anthropometric measurements, and parents’ satisfaction.ResultsOver-all concordance rate was 93% and inter-observer concordance was 89%. Non-significant differences were found between cleft and noncleft sides regarding nostril dome height, columellar length, and alar width 6 months post-operatively. 81.25% of the parents were very satisfied with the results.ConclusionOur study targeted a cohort of Egyptian patients with unilateral cleft lip, who underwent primary rhinoplasty and the time of lip repair, showing favorable results, supporting the literature advocating for this timing, but limited by relatively short follow up period. To the best of the authors’ knowledge, this is the first study in Egypt to highlight the outcomes and direct experience for primary rhinoplasty with cleft lip repair in an Egyptian population.

Psychiatric symptom profiles of inpatient refugees in Egypt: insights from a single center study

BackgroundThe global surge in refugee populations has sparked considerable apprehension regarding their mental health. This study explores the symptom profile and associated factors among refugee patients admitted to Okasha Institute of Psychiatry, Ain Shams University, hospitals between 2018 and 2021.MethodsA retrospective analysis was conducted utilizing the medical records of refugee patients admitted to Okasha Institute of Psychiatry between 2018 and 2021. Data collection encompassed socio-demographic characteristics, diagnoses, reported stressors, and specific symptom profiles.ResultsThe study involved 36 refugee patients, averaging 26.7 years, predominantly female (61.1%), and predominantly of Sudanese origin (45.9%). Prevalent diagnoses included bipolar disorder (36.8%), schizophrenia (26.3%), and major depressive disorder (13.2%). A diverse array of stressors emerged, with immigration-related issues ranking highest (21.2%). Other noteworthy stressors comprised marital conflicts (15.2%) and house-related difficulties (15.2%).ConclusionThis study highlighted the prevalence of severe mental illnesses, varied stressors, and distinct symptom profiles in refugees with psychiatric admissions and underscored the imperative for culturally sensitive and trauma-informed mental health services. Further research is imperative to devise effective interventions and enhance the mental health outcomes of refugee populations.

FCGR3A V158F gene polymorphism and trastuzumab response in HER2-positive breast cancer patients

Breast cancer is considered a multifactorial disease, with genetic factors playing an important role in diagnosis and treatment. FCGR3A encodes the receptor for the Fc portion of immunoglobulin G that has been linked to the trastuzumab response. Our study aimed to investigate the association of FCGR3A-V158F gene polymorphism with breast cancer and to evaluate the impact of FCGR3A-V158F gene polymorphism on trastuzumab response in HER2-positive breast cancer patients. The study was conducted on eighty breast cancer patients who were collected from the Department of Oncology at Ain Shams University Hospitals; in addition, twenty age-matched healthy subjects were taken as a healthy control group. Patients were further sub-classified according to their responses. The study showed that there were no statistically significant differences between patients and controls regarding FCGR3A-V158F gene polymorphism genotypes. However, there was a significant association between the concordance of this polymorphism and the response to trastuzumab therapy among the patient’s group. V/V is associated with better treatment response and overall survival (OS) compared to F/V and F/F alleles. Assessment of FCGR3A-V158F gene polymorphism might be useful in making a treatment decision in HER2-positive breast cancer patients.

A modified protocol merging two published techniques for computer guided zygomatic implants surgery: a technical note

ObjectivesZygomatic implant surgery can be difficult due to the limited intraoperative visibility of the surgical field and the complex anatomy of the zygomatic bone, which could lead to serious complications. This study aims to assess the accuracy of zygomatic implants placement using computer-guided surgical templates.Materials and methodsA total of 13 zygomatic implants were placed in four participants. Double-sleeve drill guides were used with the help of computer-guided surgical templates designed with a lateral window. The accuracy was evaluated by measuring the linear deviations regarding the implants’ platforms and apices’ positions in addition to the angular deviations. Moreover, deviations of both implants from three fixed planes of space were measured.ResultsThe mean linear deviation at platforms was 2.44 mm ± 1.57 and at the apices 2.32 mm ± 1 while the mean angular deviation was 3.6˚ ± 1.92. Differences at the entry points were 0.43 ± 1.79 mm, 0.39 ± 1.12 mm, and − 0.54 ± 2.00 mm from the mid-sagittal, horizontal, and coronal planes respectively. Differences at the exit points were − 0.75 ± 1.25 mm, -0.06 ± 1.09 mm, and 0.63 ± 1.24 mm from the same planes respectively. Within all planes, there was no statistically significant difference.ConclusionGiven the limitations of this study, the use of the computer-guided surgical templates augmented by the double sleeve drill guides allowed favorable control over the tip of the long surgical drill away from vital structures during the zygomatic implant osteotomy. It also allowed control over alveolar crest osteotomy and its placement in a favorable prosthetic position. Overall, this protocol should be considered for further research and improvement to allow more predictable surgical outcomes while preventing the occurrence of complications. Before conducting this study, the protocol was reviewed and approved by the Research Ethical Committee of Faculty of Dentistry, Ain Shams University in meeting no. (105), on 15th of July 2020 with the application no.: (FDASU-RecD072029).

Clinical, laboratory, and echocardiographic characteristics of critical multisystem inflammatory syndrome in children: a retrospective, observational study

ObjectiveMultisystem inflammatory syndrome in children (MIS-C) is a critical childhood disease that is associated with coronavirus disease (COVID-19). We aimed to describe the clinical, laboratory, and echocardiographic characteristics and outcome of critical MIS-C cases in Egyptian children during the first wave of the COVID-19 pandemic.DesignA retrospective, observational study.SettingA single-center tertiary pediatric intensive care unit (PICU).In Ain Shams university hospitals Cairo EgyptMethodsChildren admitted to the PICU diagnosed with severe MIS-C as per the Centers for Disease Control’s definition from June 23, 2020, to August 22, 2020, were included.ResultsThe patient’s mean age was 7.45 (interquartile range [IQR], 4.23) years, and the cause of PICU admission was hypotension and shock. All patients had a fever for 4.8 (IQR, 2.5) days before shock developed. Overall, 68% had a gastrointestinal manifestation, and 55.6% had a rash. Thirty-five of 45 patients had ≥ 4 elevated inflammatory markers. The cardiac troponin I level was elevated in 35 of 45 patients. The most common cardiac condition was valvulitis (tricuspid regurgitation, 29/45; mitral valve regurgitation, 28/45; pulmonary valve regurgitation, 5/45; atrial valve regurgitation, 4/45). Twenty-one patients had an impaired ejection fraction < 50%, and 17 patients had coronary dilatation. Six patients had pericardial effusion, 1 patient had dilated pulmonary arteries, and 6 patients (13.3%) died of their associated comorbidities. The mean PICU length of stay among patients with no associated comorbidities was 7 days.ConclusionsCritical cases of MIS-C had a spectrum of different cardiac conditions, with valvulitis being the most common one. The worst outcome occurred in patients with comorbidities and infants.

Prognostic nutritional index as a predictor of mortality among patients admitted to ICU with acute exacerbation of chronic obstructive pulmonary disease

BackgroundThe PNI is a metric that may assess the combined impact of the inflammatory process and nutritional condition. It may be beneficial in evaluating the nutritional state of patients with AECOPD.In recent years, it has also been utilized for prognostic assessment of cases admitted to the critical care unit.Aim of the workThe objective of the research was to assess the relationship between PNI and the prognosis for ICU patients with AECOPD.Patients and methodsThis was a prospective cross-sectional observational research carried out in the RICU of Ain Shams University Hospitals from April 2023 to March 2024. The study included 161 AECOPD patients who were admitted to RICU. All patients underwent demographic data collection, special habits and comorbid conditions evaluations, and hematological indices with laboratory markers and ABG. ICU and hospital stay duration, SOFA score, and SAPS II were also documented. The PNI value was computed using the following equation: the formula to calculate the value is 10 times the serum albumin concentration in grams per deciliter plus 0.005 times the total lymphocyte count in cubic millimeters. The main measure of interest was the death rate within 30 days for all causes. Additional measures were the duration of stay in the ICU, the duration of hospitalization, and the rate of MV.ResultsThere was a significant relationship between PNI and type of respiratory failure, mechanical ventilation, fate, hypertension, and diabetes. One hundred five (65.2%) of the patients were extubated and discharged, while 56 (34.8%) of them died. The study also noted a significant positive relationship among PNI and HCT, lymphocytic %, HB, and albumin. However, there was a significant negative relationship between PNI and age, RDW, WBC, neutrophil count, neutrophil %, NLR, CRP, SAPSII, and SOFA. The SAPS II score (with SAPS II mortality) had greater AUROC in predicting mortality than PNI, NLR, and SOFA. The optimal cut-off value for PNI in this study was ≤ 29 with sensitivity 82.14% and specificity 56.19%.ConclusionThe study showed that PNI can be a useful biomarker for AECOPD. PNI with SAPS II scores on admission to ICU were closely correlated to adverse outcomes.

Mental health and binge-watching behavior among university students in Egypt

BackgroundBinge-watching has become increasingly popular in recent years. Although it can provide a form of entertainment and mood regulation, it has also been associated with adverse mental health issues. In this study, we explored the association between binge-watching behavior and mental health. MethodsUsing a cross-sectional survey conducted from May to November 2018, we surveyed 535 participants over 18 years old from Ain Shams University by using a combination of online and pen-and-paper methods. Data on sociodemographic characteristics and TV series watching patterns were collected, and participants completed the Binge-Watching Engagement and Symptoms Questionnaire (BWESQ), the Brief Symptom Inventory (BSI-18), and the Subjective Happiness Scale (SHS).ResultsAmong the 535 participants surveyed, 333 were retained and divided into three groups (i.e., non-binge-watchers, trouble-free binge-watchers, and problematic binge-watchers) in accordance with previous binge-watching research. Significant between-group differences were found in terms of relationship status, commonly used devices (mobile, laptop, TV), and perceived dependency on TV series watching. Problematic binge-watchers showed significantly higher scores for all BWESQ and BSI-18 subscales.ConclusionTrouble-free binge-watchers and problematic binge-watchers were more likely to be single than non-binge-watchers and demonstrated a marked preference for using mobile phones and laptops over traditional television. A significant positive relationship was found between problematic binge-watching and symptoms of depression, anxiety, and somatization.

Psychiatric outcomes among COVID-19 egyptian patients at ain shams university quarantine hospitals: A cross-sectional study

BackgroundPsychological repercussions resulting from coronavirus disease 2019 (COVID-19) have been encountered, such as anxiety, depression, insomnia, and post-traumatic stress disorder (PTSD). The study aimed to assess the frequency and severity of PTSD, depression, and anxiety in a sample of Egyptian patients with COVID-19 infection and analyze potential risk factors. The current study is a descriptive cross-sectional, hospital-based study, conducted from August 2020 to June 2021. The sample was selected from patients diagnosed with COVID-19 infection at Ain Shams University hospitals (outpatient clinics and inpatient units). Patients underwent a COVID severity criteria scoring system, structured clinical interview for DSM-IV (SCID-I), PTSD checklist–Civilian Version (PCLC), Beck depression inventory, and Taylor’s manifest anxiety scale.ResultsPTSD was observed in 79.29% of the study sample, 61.43% had depression, and 18.57% had anxiety. The severity of COVID-19 infection was significantly associated with PTSD severity mean scores (P value = 0.027). Furthermore, a significant relationship was observed between the severity of depression and COVID-19 infection severity (P value = 0.028). The number of comorbid medical risk factors demonstrated significance to PTSD severity (P value = 0.014).ConclusionA significant portion of the study’s patients experienced psychiatric consequences following COVID-19 infection, with 79.29% developing PTSD, 61.43% suffering from depression, and 18.57% experiencing anxiety. Various factors, such as the presence of chronic medical illnesses and the number of co-morbid medical risk factors, were observed to contribute to these psychiatric outcomes. Therefore, comprehensive psychiatric assessment and management in COVID-19 patients especially with severe forms of the disease and hospitalized patients are mandatory.

Nasoalveolar Molding in Lately Presented Moderate to Severe Unilateral Cleft Lip and Palate Infants: Does it Add?

Alignment of the alveolar segments with early nasal cartilage tackling is the foundation upon which excellent surgical results are dependent. The purpose is to evaluate the short-term effect of triple combination of passive alveolar molding with early nasal molding augmented by controlled corrective power of lip tapping in lately presented moderate to severe unilateral complete cleft lip and palate infants. A prospective case series study was conducted in Plastic and Maxillofacial Surgery Department, Ain Shams University in collaboration with Orthodontics Department, from January 2021 till June 2023, 15 infants elder than 2 months till 6 months were enrolled in the study. Eight nasal anthropometric measurements ratios through 2-dimension assessment and 4 maxillary arch measurements ratios through 3-dimension assessment were recorded. Extraoral results revealed clinically and statistically decrease of nasal width, alar base width, alar base height ratios, and columellar angle, while increase of nasal height, nasal dome height, columellar length, and alar projection length ratios. Intraoral results revealed clinically and statistically decrease in cleft width with maintained posterior arch width and intercanine width. In conclusion, this triple combination helped in presurgical lessening the alveolar and nasal deformity of such elder infants in a shorter time in comparison with other conventional methods with lesser number of appointments decreasing burden of care to their families improving their compliance.

C-reactive protein/albumin ratio versus lactate/albumin ratio as an outcome predictor for patients with sepsis and septic shock in hospital stay

Background &amp; Objective: Pre-emptively identifying individuals at risk of developing sepsis and septic shock remains challenging. In septic patients, the Lactate/Albumin Ratio (LAR) and C-reactive protein (CRP)/Albumin ratio (CAR) have been suggested to be promising prognostic indicators for prediction of intensive care unit (ICU) mortality. We compared the prognostic values of CAR and LAR in patients with sepsis and septic shock. Methodology: Eighty adult patients diagnosed with sepsis and admitted to the ICUs of Ain Shams University Hospitals, were included in this observational prospective study. CRP levels, serum lactate, serum albumin, complete blood count (CBC), procalcitonin levels, and SOFA scores were assessed upon admission, with subsequently observing 28-day mortality among the selected patients. Results: CAR values were comparable between the mortality and survival groups (P = 0.807). However, LAR values were significantly elevated in the mortality group vs the survival group (P = 0.044). ROC analysis for mortality indicated that LAR had an AUC of 0.633 at a cutoff value &gt; 0.68, achieving sensitivity and specificity of 89.4% and 21.2%, respectively. In contrast, CAR had an AUC of 0.484 at a cutoff value ≥ 1.54, with sensitivity and specificity values of 63.8% and 57.6%, respectively. Length of ICU stay (P &lt; 0.001), duration of mechanical ventilation (P &lt; 0.001), cardiovascular support (P &lt; 0.001) and the need for renal replacement therapy (P &lt; 0. 039), were increased in the mortality group compared to the survival group. Conclusion: Lactate/albumin ratio is superior and more reliable bio-marker predictor compared to C-reactive protein (CRP)/albumin ratio for ICU mortality. Abbreviations: CAR - C-reactive protein/albumin ratio; CRP - C-reactive protein; ICU - intensive care unit; LAR - Lactate/Albumin Ratio; Keywords: Albumin; CRP To Albumin Ratio; Lactate; Lactate to Albumin Ratio; Mortality; Sepsis; Septic Shock; SOFA; Survival Citation: Abdou K, Mounir M, Abdelmohsen S, Salem S, Ali A. C-reactive protein/albumin ratio versus lactate/albumin ratio as an outcome predictor for patients with sepsis and septic shock in hospital stay. Anaesth. pain intensive care 2023;28(5):901−907; DOI: 10.35975/apic.v27i5.2571 Received: July 29, 2024; Reviewed: August 23, 2024; Accepted: August 28, 2024

A Randomized Trial for Postoperative Analgesia in Patients Undergoing Percutaneous Nephrolithotomy: Intravenous Lidocaine Infusion vs. Ultrasound Guided Erector Spinae Plane Block

Abstract Author affiliations: 1. Kirolos Hany Abd-Allah Shawky, MB, BCh, Resident of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University, Abbasseya, Cairo, Egypt; Email: 2. Gihan Seif Elnasr Mohamed, Professor of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University. Abbasseya, Cairo, Egypt; Email: 3. Ibrahim Mamdouh Esmat, Professor of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University. Abbasseya, Cairo, Egypt; Email: 4. Noha Refaat Mohamed, Assistant Professor of Clinical Pathology, Faculty of Medicine, Ain Shams University. Abbasseya, Cairo, Egypt; Email: 5. Tarek Mohamed Ashoor, Assistant Professor of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Ain Shams University. Abbasseya, Cairo, Egypt; Email:

Assessment of Blood Products Transfusion in Tertiary Neonatal Intensive Care Units Ain Shams University

Abstract Background Preterm Neonates, especially very low birth weight infants, remain a category of patients with high transfusion needs. Appropriate transfusion of neonates is vital when the potential clinical benefit outweighs the risk. However, the association between transfusion and adverse outcomes remains inconclusive. Aim Of The Work To evaluate transfusion practices in Tertiary Neonatal Intensive Care Units at Ain Shams University. Patients and Methods A cross sectional observational study was conducted on patients selected from Tertiary Neonatal Intensive Care Units at Ain Shams University- Children’s hospital. There were 703 neonates (29.64%) who received at least one type of blood products (packed red blood cells, platelets, fresh frozen plasma or cryoprecipitate) transfusion or underwent exchange transfusion during their hospital stay. All neonates receiving blood products transfusions were assessed for full history taking, clinical parameters i.e. gestational age, birth weight and general examination, indications for admission whether medical or surgical indications. Co-morbid illness such as bronchopulmonary dysplasia, necrotizing enterocolitis, retinopathy of prematurity, sepsis and patent ductus arteriosus were also noted. In addition, the indications for each of blood products transfusion i.e. anemia, exchange transfusion, thrombocytopenia, sepsis or other indications. Then, the requisition was assessed for pre- and post-transfusion laboratory parameters. Results Packed red blood cell was the most frequent blood component transfused (82.4%) and the main indication was anemia of prematurity (34.8%). There was a highly statistically significant increase in each of hemoglobin and hematocrit (HCT) post transfusion (with P value &amp;lt;0.0001) and a highly statistically decrease in the required median fraction of inspired oxygen (FiO2) (with P value &amp;lt;0.0001). 681 neonates (96.9%) presented with comorbidities; the most common comorbidity was neonatal sepsis in 81.2%. Packed red blood cells (PRBCs) transfusions were highly statistically significant related to comorbidity development. Conclusion Majority of blood transfusions occur during the first 2 weeks of life. Gestational age, birth weight, underlying disease of neonates, the need for oxygen support and blood collection within first two weeks of birth influence their transfusion needs. Sepsis remains the foremost etiological factor for blood component transfusion.

Impact of COVID19 on Availability of Anti-Epileptic Medications in Pediatric Neurology Clinic

Abstract Background In epilepsy patients, the pandemic has led to postponement of outpatient visits, cancellation of epilepsy-related tests, such as electroencephalograms (EEG) and magnetic resonance imaging (MRI) studies, and even difficulties in attending emergency situations due to saturation of the healthcare services, which can create life threatening situations for patients who present to the emergency rooms with non-COVID related complaints. Aim of the Work To evaluate effect of COVID-19 pandemic on supplying anti-epileptic medications for children following in the Pediatric Neurology Clinic, Ain Shams University. Patients and Methods An observational cross-sectional study was carried out at Pediatric Neurology Clinic, Children’s hospital, Ain Shams University. The study included 126 care givers of children with epilepsy who were aged 2 to 18 years, have a diagnosis of Epilepsy (including idiopathic and cryptogenic epilepsy) for at least one year before the onset of the COVID19 pandemic. I.e., Epilepsy diagnosed at or before March 2019 and are following up at the Pediatric Neurology Clinic, Children’s Hospital, Ain Shams University. Results Our study showed only 22% of the epileptic children had trouble in obtaining the anti- epileptic drug/drugs; where the most common problem was financial problems followed by drug shortage. Most of the epileptic children didn’t have a change in the treatment regimen during the last year. Conclusion Most children with epilepsy did not experience a significant change in their clinical conditions because of healthcare reorganization during the COVID-19 emergency.

Association between the Frequency of Social Media Exposure and Mental Health Problems among Employees at Ain Shams University during the COVID-19 Pandemic

Abstract Background The COVID-19 pandemic created a threat to human well-being. The rapid spread of the coronavirus disease combined with quarantine measurements made people use social media platforms more than before. The improper and excessive use of social media affected people’s mental health, resulting in increased levels of depression and anxiety. Objective This study aimed To measure the frequency of anxiety and depression in the last 12 months, during the COVID-19 pandemic among employees at Ain Shams University. And to measure the association between social media exposure and mental health, including anxiety and depression among employees at Ain Shams University in the last 12 months, during the Covid- 19 pandemic. Method Data was gathered through a 6- month cross-sectional analytical study including 405 staff members who were asked to answer a standardized self-administered questionnaire from 1 September 2021 to 31 March 2022. The questionnaires contain three parts: (1) socio- demographic information (2) Daily use of social media and other types of media (3) Measurement of levels of anxiety and depression using the GAD-7 and PHQ-9 scales Result Overall 405 participants were enrolled, 203 males and 202 females ranging from the age (20-30) to 51 and above. (78.8%) of the study sample used social media to be updated about the pandemic. (40.7%) and (41.6%) of the participants who visited social media six times or more per day scored severely depressed on the PHQ-9 scale and severely anxious on the GAD-7 scale, respectively. Furthermore, (33.1%) of participants who used social media for 4 hours or more had severe depression according to the PHQ- 9, and (29.9%) had severe anxiety according to the GAD-7. Conclusion and Recommendations Our findings offer some evidence for a troubling relationship between COVID-19-related media exposure on social media and psychological problems, and therefore understanding these problems can help to prevent them in future crises. Additionally, it could help governments monitor the spread of misinformation.

Prevalence and Risk Factors of Non-Suicidal Self-Injury in a Sample of Egyptian University Students in Ain Shams University

Abstract Background Non-suicidal self-injury (NSSI) is a global health concern, with a prevalence ranging from 1.5% to 54.8%. Typically starting during adolescence, it was proposed that there is a correlation between NSSI and adverse childhood experiences (ACEs), such as parental antagonism, neglect, physical abuse, and sexual abuse. Many turn to NSSI as a strategy to cope with emotional regulation difficulties, using it as a means to navigate and manage their emotions effectively. Aim of the Work Examining the prevalence of non-suicidal self-injury (NSSI) in young adult students at Ain Shams University, exploring the methods and functions of NSSI, assessing the correlation with emotional regulation difficulties and adverse childhood experiences. Patients and Methods This study is an observational cross-sectional study, A convenient sample of 400 Undergraduate students at Ain Shams university was obtained equally distributed between the Faculties of Medicine and Education. Results Among Ain Shams University students, non-suicidal self-injury (NSSI) prevalence was 18% engaging in NSSI last year, and 4.3% reporting repetitive instances. Common forms included pounding oneself (16.2%), cutting (15.4%), and biting (15.4%). NSSI functions revealed relief from negative feelings (14.2%) and self-punishment (11.7%) as major goals. Academic challenges were a top motivating factor, alongside guilt, problem confrontation difficulties, and unstable relationships. Those with multiple adverse childhood experiences (ACEs) were more likely to engage in NSSI, showing a positive correlation with NSSI frequency. Emotional regulation difficulties, were also linked to NSSI, indicating a predictive relationship between emotional regulation challenges and self-injurious behavior in young adults. Conclusion Non-suicidal self-injury (NSSI) is prevalent among young adults. The study emphasizes the considerable influence of adverse childhood experiences (ACEs) and challenges in emotional regulation on NSSI in this demographic. In conclusion, these results underscore the crucial role of addressing early life experiences and emotional regulation to comprehend and prevent NSSI among young adults.

Effect of Health Education on Knowledge and Attitude of Parents towards Paediatric Epilepsy in Egyptian Children

Abstract Background Epilepsy remains one of the most common neurological diseases in the world but seems to be widely misunderstood, especially in low-income countries. Patients with epilepsy can face considerable stigma in society, Parents’ knowledge on care of children greatly influences the health status of a child by reducing the mortality and morbidity rate. Aim of the Work Assess the attitude and knowledge toward paediatric epilepsy amongst parents of paediatric patients with epilepsy and other parents seeking advice in the out-patient clinic, Assess the effect of educational program of home management of seizures on knowledge and practice of parents. Patients and Methods This comparative cross-sectional study included 100 parents of children with epilepsy who follow up in Paediatric neurology clinic, Ain Shams University (Group A) and 300 parents of normal children who sought advice in Paediatric outpatient clinic, Ain Shams University (Group B) in which sociodemographic characteristics were collected and a validated questionnaire was distributed before and after an educational session about epilepsy facts and its first aid. Results The study revealed significant difference between study and control groups in their baseline knowledge about epilepsy, in terms of “epilepsy being an organic disease, rather than a psychiatric illness or an evil spirit” (67.0% vs. 39.8%, P &amp;lt; 0.001) respectively, and management of a child experiencing a seizure where 6% of group A answered “do not know” vs 74.6% of group B, P &amp;lt; 0.001). Regarding attitude towards epilepsy, both groups showed negative attitude towards epilepsy; 78% of group A and 66% of group B agreed that epilepsy is a factor that strongly impair child learning. Similarly, 81% of group A and 65% of group B reported that epilepsy can strongly limit sports and leisure activities. In terms of effect of educational effect, group A showed significant difference in number of correct answers regarding manifestation and first aid measures for a child with seizure before and after education (12% vs 51% P &amp;lt; 0.001 &amp; 45% vs 75% P = 0.009) respectively. Moreover, group B showed significant difference in correct answers for both topics after education (0% vs. 49.2 % P, 0.001 &amp; 0% vs 71.2% P &amp;lt; 0.001). Conclusion Our results highlight the need for educational programs and targeted awareness campaigns, to reduce misconceptions and promote a more supportive environment for individuals with epilepsy.