This research delves into the repercussions of employing pilot and zeta herbicides at varying application rates to counteract the growth of common sorghum within soybean fields. The investigation is conducted within the specific environmental context of irrigated typical gray soils prevalent in the Tashkent region. The central focus of this study is to gain a comprehensive understanding of the multifaceted impacts these herbicides exert on the growth trajectory, developmental milestones, and eventual yield of soybean plants. By assessing the influence of pilot and zeta herbicides across different dosage levels, this study contributes to elucidating the potential benefits or challenges that arise from their application in this agricultural setting. Furthermore, this research endeavors to provide critical insights into the economic efficiency of employing these herbicides, thereby offering a holistic perspective on the viability of incorporating such chemical interventions within soybean cultivation practices in the Tashkent region. The implications of this study extend beyond agronomic parameters, delving into the intricate interplay between herbicide application, crop growth, and economic considerations. The findings are poised to offer valuable guidance to farmers, researchers, and policymakers who are vested in optimizing agricultural practices while considering both the ecological and economic dimensions. Ultimately, this investigation strives to enrich the body of knowledge concerning herbicidal interventions and their potential repercussions in the realm of soybean cultivation within distinct agro-ecological contexts.