Age replacement strategies, where a unit is replaced upon failure or on reaching a predetermined age, whichever occurs first, provide simple and intuitively attractive replacement guidelines for technical units. Within theory of stochastic processes, the optimal preventive replacement age, in the sense of leading to minimal expected costs per unit of time when the strategy is used for a sequence of similar units over a long period of time, is derived by application of the renewal reward theorem. The mathematical solution to the problem of what is the optimal age for replacement is well known for the case when the parameter values of the underlying lifetime distributions are known with certainty. In actual practice, such is simply not the case. When these models are applied to solve real-world problems, the parameters are estimated and then treated as if they were the true values. The risk associated with using estimates rather than the true parameters is called estimation risk and is often ignored. When data are limited and (or) unreliable, estimation risk may be significant, and failure to incorporate it into the model design may lead to serious errors. Its explicit consideration is important since decision rules that are optimal in the absence of uncertainty need not even be approximately optimal in the presence of such uncertainty. In the present paper, for efficient optimization of statistical decisions under parametric uncertainty, the pivotal quantity averaging (PQA) approach is suggested. This approach represents a new simple and computationally attractive statistical technique based on the constructive use of the invariance principle in mathematical statistics. It allows one to carry out the transition from the original problem to the equivalent transformed problem (in terms of pivotal quantities and ancillary factors) via invariant embedding a sample statistic in the original problem. In this case, the statistical optimization of the equivalent transformed problem is carried out via ancillary factors. Unlike the Bayesian approach, the proposed approach is independent of the choice of priors. This approach allows one to eliminate unknown parameters from the problem and to find the better decision rules, which have smaller risk than any of the well-known decision rules. To illustrate the proposed approach, the numerical examples are given.