This study firstly examines the quality of marine eco-environment in Africa using Tapio decoupling model, and analyzes the sustainability level of the development of “population agglomeration - marine environment - economic growth”. Secondly, a series of econometric tools, such as ARDL, FMOLS, AMG model and DH panel causality test, are used to investigate the long- and short-term impacts of economic growth, population agglomeration, marine capture and energy consumption on the African marine eco-environment, and to analyze the differences between the sub-regions in Africa. The results indicate that: Adebayo and Kirikkaleli (2021) (Adebayo and Kirikkaleli, 2021) the decoupling state of “population-environment” has shifted from expansive negative decoupling to more optimized strong decoupling, and “economy-environment” has gradually changed from strong negative decoupling and expansive negative decoupling to strong decoupling. Ali et al. (2017) (Ali et al., 2017) There existed a bi-directional causal relationship between the degree of marine environment degradation and economic growth, population agglomeration, marine capture and energy consumption. Al-Mulali and Sab (2012) (Al-Mulali and Sab, 2012) In the short term, the economic EKC hypothesis does not hold in North and West Africa, while Central, East and Southern Africa are consistent with the EKC hypothesis. In the long term, the EKC hypothesis is valid in Central, East and Southern Africa, while is not valid in North and West Africa. Overall, reducing population agglomeration levels, marine fishing and energy consumption might mitigate marine environmental degradation in Africa.