This research proposes advanced model-based control strategies for a countercurrent flow plate heat exchanger in a virtual environment. A virtual environment with visual and auditory effects is designed, which requires a mathematical model describing the real dynamics of the process; this allows parallel fluid movement in different directions with hot and cold temperatures at the outlet, incorporating control monitoring interfaces as communication links between the virtual heat exchanger and control applications. A multivariable and non-linear process like the plate and countercurrent flow heat exchanger requires analysis in the controller design; therefore, this work proposes and compares two control strategies to identify the best-performing one. The first controller is based on the inverse model of the plant, with linear algebra techniques and numerical methods; the second controller is a model predictive control (MPC), which presents optimal control actions that minimize the steady-state errors and aggressive variations in the actuators, respecting the temperature constraints and the operating limits, incorporating a predictive model of the plant. The controllers are tested for different setpoint changes and disturbances, determining that they are not overshot and that the MPC controller has the shortest settling time and lowest steady-state error.