Adults In Beijing Research Articles

Source apportionment and health-risk assessment of PM2.5-bound elements in indoor/outdoor residential buildings in Chinese megacities

Particulate matter with a diameter of 2.5 μm or smaller (PM2.5) in indoor environments originates from both indoor and outdoor sources, influencing associated human health risks through different compositions. This study simultaneously collected and analyzed indoor and outdoor PM2.5 samples in three major Chinese megacities—Beijing, Shanghai, and Shenzhen—to characterize PM2.5 sources and assess their health impacts. A total of seven distinct sources, both indoor and outdoor, were identified for PM2.5: indoor activities, metal smelting, industrial activities, soil dust, vehicle emissions, coal combustion, and fuel oil combustion. Indoor activities accounted for approximately 20% of the residential indoor PM2.5, with the remainder predominantly due to outdoor PM2.5 infiltration. The contributions of indoor activities to noncarcinogenic and carcinogenic risks ranged from 3.6% to 28.5%, whereas outdoor PM2.5 sources posing greater health risks. The cumulative noncarcinogenic risks for adults in Beijing, Shanghai, and Shenzhen were 0.99, 1.15, and 0.72, respectively, slightly higher than those for children. The cumulative carcinogenic risks for adults were approximately five times those for children, with values of 6.90 × 10−5, 6.34 × 10−5, and 6.83 × 10−5, respectively, all surpassing the acceptable limit. Noncarcinogenic risks were predominantly attributed to Ni, Co, and Mn, contributing over 80% to the total risk, while Cr was the primary contributor (>89%) to carcinogenic risks. Indoor exposure accounting for over 80% of noncarcinogenic and carcinogenic risks for adults, and exceeding 90% for children. This study provides significant insights into the effective control of PM2.5 pollution and the reduction of health risks from a source perspective.

Occurrence of legacy and emerging organophosphate flame retardants (OPFRs) on silicone wristbands: Comparison within couples

Novel organophosphate flame retardants (OPFRs) are recently identified and highly detected in indoor dusts, but their personal exposure was not clear. Here, wristband was used to estimate non-dietary exposure to emerging OPFRs in comparison with legacy OPFRs in 93 adults in Beijing, China. Comparison of studies in wristband monitoring data showed a clear difference in profiles of legacy OPFRs between China and United States, where tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) was usually the dominant OPFR in the United States, but triphenyl phosphate has the highest contribution to total OPFRs in China. Five emerging OPFRs, including diethylene glycol bis(bis(2-chloroisopropyl) phosphate) (DEGBBCPP) and bis(2-ethylhexyl) phenyl phosphate (BEHPP), were detected in above 45 % of wristbands. The median concentration of DEGBBCPP (2.2 ng/g) was about three times higher than TDCIPP (0.76 ng/g), a legacy chloro-OPFR. Both emerging and legacy OPFRs were significantly correlated within 40 pairs of couples, suggesting major exposure in their homes. Wristbands from husbands had significantly higher tris(2-butoxyethyl) phosphate (TBOEP) and DEGBBCPP, while 2-ethylhexyl diphenyl phosphate (EHDPP) was significantly higher in wives' bands, suggesting gender-related exposure sources for these OPFRs.

Association Between Street Greenery And Physical Activity Among Chinese Older Adults In Beijing, China

Association Between Street Greenery And Physical Activity Among Chinese Older Adults In Beijing, China

Exploring the role of interaction in older-adult service innovation: insights from the testing stage

In the context of global aging trends, service innovation targeting older adults is becoming increasingly crucial. Because the traditional focus areas of service innovation have predominantly been design and implementation, a significant gap in the existing literature overlooks the criticality of the testing phase. This oversight is particularly notable in relation to the unique attributes of the older adult population and their interaction dynamics with technology teams in service innovation. To bridge this lacuna, this study introduces a comprehensive framework, meticulously crafted for the testing stage of service innovation tailored to older adults. To validate this framework, a rigorous, four-year empirical research project was undertaken with one of the foremost service providers for older adults in Beijing. The findings robustly support the efficacy of the proposed framework, revealing the indispensable role of the testing phase in ensuring service innovations are aptly aligned with the needs and preferences of the aging demographic. This research enriches the discourse in service innovation, thus underscoring the imperative to integrate the testing phase as a fundamental component in the holistic approach aimed at catering effectively to an aging population.

Fine particulate matter exposure and systemic inflammation: A potential mediating role of bioactive lipids

Inflammation is a key mechanism underlying the adverse health effects of exposure to fine particulate matter (PM2.5). Bioactive lipids in the arachidonic acid (ARA) pathway are important in the regulation of inflammation and are reportedly altered by PM2.5 exposure. Ceramide-1-phosphate (C1P), a class of sphingolipids, is required to initiate ARA metabolism. We examined the role of C1P in the alteration of ARA metabolism after PM2.5 exposure and explored whether changes in the ARA pathway promoted systemic inflammation based on a panel study involving 112 older adults in Beijing, China. Ambient PM2.5 levels were continuously monitored at a fixed station from 2013 to 2015. Serum cytokine levels were measured to assess systemic inflammation. Multiple bioactive lipids in the ARA pathway and three subtypes of C1P were quantified in blood samples. Mediation analyses were performed to test the hypotheses. We observed that PM2.5 exposure was positively associated with inflammatory cytokines and the three subtypes of C1P. Mediation analyses showed that C1P significantly mediated the associations of ARA and 5, 6-dihydroxyeicosatrienoic acid (5, 6-DHET), an ARA metabolite, with PM2.5 exposure. ARA, 5, 6-DHET, and leukotriene B4 mediated systemic inflammatory response to PM2.5 exposure. For example, C1P C16:0 (a subtype of C1P) mediated a 12.9 % (95 % confidence interval: 3.7 %, 32.5 %) increase in ARA associated with 3-day moving average PM2.5 exposure, and ARA mediated a 27.1 % (7.8 %, 61.2 %) change in interleukin-8 associated with 7-day moving average PM2.5 exposure. Our study indicates that bioactive lipids in the ARA and sphingolipid metabolic pathways may mediate systemic inflammation after PM2.5 exposure.

Ill-fitting prosthesis is associated with an increased risk of elevated blood pressures.

Previous studies focused on the benefits of adequate prosthodontic treatment, while few studies have investigated the prosthodontic-related risks to health. As a modifiable oral health indicator, the association of ill-fitting prosthesis (IFP) with hypertension has not been fully explored. This cross-sectional study involved 158,659 adults in Beijing (2009-2017) receiving intra-oral examinations and blood pressure measurements. Logistic regression models were applied to assess the association of IFP with the prevalence of hypertension, systolic blood pressure (SBP) ≧ 140 mmHg and diastolic blood pressure (DBP) ≧ 90 mmHg, as well as subgroup analyses by different fixed IFP subgroups (according to involved teeth number) and removable IFP subgroup. We further investigated effect modifications among stratified populations. 158,659 individuals were included for analysis, 346 (26.86%) in IFP group and 27,380 (17.40%) in non-IFP group (p < 0.001) were hypertensive. After adjustment of sex, age, obesity, dyslipidaemia, diabetes, hsCRP, family history of CVD, self-reported smoking, self-reported drinking and WC, ORs of hypertension, SBP ≧ 140 mmHg and DBP ≧ 90 mmHg were 1.330 (95% CI: 1.162-1.522), 1.277 (95% CI: 1.098-1.486) and 1.376 (95% CI: 1.186-1.596), respectively (p < 0.05). Furthermore, after full adjustment, the number of involved teeth showed a significant incremental trend with hypertension risk in the population with and without IFP (p for trend <0.001). The IFP-blood pressure associations were more pronounced in females, 18-60 years, non-obese and diabetic participants. As a modifiable oral indicator, IFP was significantly associated with a higher risk of hypertension.

Predicting Personal Exposure to PM2.5 Using Different Determinants and Machine Learning Algorithms in Two Megacities, China

The primary aim of this study is to explore the utility of machine learning algorithms for predicting personal PM2.5 exposures of elderly participants and to evaluate the effect of individual variables on model performance. Personal PM2.5 was measured on five consecutive days across seasons in 66 retired adults in Beijing (BJ) and Nanjing (NJ), China. The potential predictors were extracted from routine monitoring data (ambient PM2.5 concentrations and meteorological factors), basic questionnaires (personal and household characteristics), and time-activity diary (TAD). Prediction models were developed based on either traditional multiple linear regression (MLR) or five advanced machine learning methods. Our results revealed that personal PM2.5 exposures were well predicted by both MLR and machine learning models with predictors extracted from routine monitoring data, which was indicated by the high nested cross-validation (CV) R2 ranging from 0.76 to 0.88. The addition of predictors from either the questionnaire or TAD did not improve predictive accuracy for all algorithms. The ambient PM2.5 concentrations were the most important predictor. Overall, the random forest, support vector machine, and extreme gradient boosting algorithms outperformed the reference MLR method. Compared with the traditional MLR approach, the CV R2 of the RF model increased up to 7% (from 0.82±0.13 to 0.88±0.10), while the RMSE reduced up to 18% (from 19.8±5.4 to 16.3±4.5) in BJ.

Relationship between exposure to fine particulate matter and cardiovascular risk factors and the modifying effect of socioeconomic status: a cross-sectional study in Beijing, China.

Accumulating research suggested that long-term exposure to fine particulate matter (PM2.5) is related to cardiovascular disease (CVD). However, evidence regarding the relationship between PM2.5 and CVD risk factors remains inconsistent. We hypothesized that this association may be partially modified by socioeconomic status (SES). To investigate the relationships and to test the modifying effect of SES, we included baseline data for 21,018 adults from September 2017 to May 2018. PM2.5 concentrations were determined by employing an amalgamation of linear measurements obtained from monitoring stations located near the participants' residential and workplace addresses. We assessed SES across several domains, including income, education, and occupation levels, as well as through a composite SES index. The results indicated that for every 10 μg/m3 increase in PM2.5 exposure, the risk of hypercholesterolemia, hyperbetalipoproteinemia, diabetes, and hyperhomocysteinemia (HHcy) increased by 7.7% [Odds ratio (OR) = 1.077, 95% Confidence Interval (CI) = 1.011, 1.146], 19.6% (OR = 1.196, 95% CI = 1.091, 1.312), 4.2% (OR = 1.042, 95% CI = 1.002, 1.084), and 17.1% (OR = 1.171, 95% CI = 1.133, 1.209), respectively. Compared to the high SES group, those with low SES are more prone to hypercholesterolemia, hyperbetalipoproteinemia, diabetes, and HHcy. Notably, the disparities in SES appear significant in the relationship between PM2.5 exposure and hypercholesterolemia as well as hyperbetalipoproteinemia. But for diabetes and HHcy, the modification effect of SES on PM2.5 shows an inconsistent pattern. In conclusion, the results confirm the association between PM2.5 and cardiovascular risk factors and low SES significantly amplified the adverse PM2.5 effect on dyslipidemia. It is crucial to emphasize a need to improve the socioeconomic inequality among adults in Beijing and contribute to the understanding of the urgency in protecting the health of vulnerable groups.

The mediating role of accelerated biological aging in the association between blood metals and cognitive function

Aging is a key risk factor in cognitive diseases. Recently, metal exposures were found associated with both biological aging and cognitive function. Here, we aim to evaluate the associations of blood metals with cognitive function and the mediated effect of biological aging. Fourteen metals were detected and biological age was calculated through Klemera and Doubal method among 514 adults in Beijing, China. The generalized linear models indicated that the copper (Cu), molybdenum (Mo), and strontium (Sr) were positively associated with biological aging [βCu (95% CI): 12.76 (9.26, 16.27); βMo (95% CI): 1.50 (0.15, 2.85)], and βSr (95% CI): 1.86 (0.68, 3.03)], while vanadium (V) was inversely related to biological aging [βV (95% CI): −0.76 (−1.48, −0.05)]. Subsequently, Cu, lead (Pb), selenium (Se), and biological aging were associated with cognitive function and further mediation analyses confirmed that biological aging partially mediated (33.98%, P = 0.019) the association of Cu and cognitive function. Additionally, we constructed a lifestyle index that implied the modifiable healthy lifestyle could slow aging to attenuate the detrimental effect of metals on cognition. Our findings provide insights into the potential pathways linking multiple metals exposure to aging and cognition and underscore the importance of adopting healthy lifestyles.

The joint effect and hemodynamic mechanism of PA and PM2.5 exposure on cognitive function: A randomized controlled trial study

BackgroundWhile PM2.5 has been shown to impair cognitive function, physical activity (PA) is known to enhance it. Nonetheless, considering the increased inhalation of PM2.5 during exercise, the potential of PA to counteract the detrimental effects of PM2.5, along with the underlying hemodynamic mechanisms, remains uncertain. MethodsWe conducted a double-blinded, randomized controlled trial among healthy young adults in Beijing, China. Ninety-three participants were randomly allocated to groups experiencing different intensities of PA interventions, and either subjected to purified or unpurified air conditions. Cognitive function was measured by the Color-Word Matching Stroop task, and the hemodynamic response was measured using functional near-infrared spectroscopy during participants performed the Stroop task both before and after the intervention. Linear mixed-effect models were used to estimate the impact of PA and PM2.5 on cognitive function and hemodynamic response. ResultsThe reaction time for congruent and incongruent Stroop tasks improved by − 80.714 (95% CI: −136.733, −24.695) and − 105.843 (95% CI: −188.6, −23.085) milliseconds after high-intensity interval training (HIIT) intervention. PM2.5 and HIIT had interaction effects on cognition, such that every 1 μg/m3 increase in PM2.5 attenuated the benefits of HIIT on reaction time by 2.231 (95% CI: 0.523, 3.938) and 3.305 (95% CI: 0.791, 5.819) milliseconds for congruent and incongruent Stroop tasks. Moreover, we divided participants into high and low PM2.5 exposure groups based on average PM2.5 concentration (32.980 μg/m3), and found that HIIT intervention in high PM2.5 concentration led to 69.897 (95% CI: 9.317, 130.476) and 99.269 (95% CI: 10.054, 188.485) milliseconds increased in the reaction time of congruent and incongruent Stroop, compared with the control group among low PM2.5. Furthermore, we found a significant interaction effects of PM2.5 and moderate-intensity continuous training (MICT) on the middle frontal gyrus (MFG) and dorsolateral superior frontal gyrus (DLPFC). PM2.5 and HIIT had a significant interaction effect on the DLPFC. ConclusionsHIIT improved cognitive function, but the cognitive benefits of HIIT were attenuated or even reversed under high PM2.5 exposure. The activation of the DLPFC and MFG could serve as hemodynamic mechanisms to explain the joint effect of PA and PM2.5.

Study on the relationship between secondhand smoke exposure and dyslipidemia in adult residents in Beijing

Objective: To understand the relationship between secondhand smoke exposure and dyslipidemia among adults in Beijing and to provide a scientific basis for relevant intervention. Methods: Data were from Beijing Adult Non-communicable and Chronic Diseases and Risk Factors Surveillance Program in 2017. A total of 13 240 respondents were selected by multistage cluster stratified sampling method. The monitoring contents include a questionnaire survey, physical measurement, collection of fasting venous blood, and determination of related biochemical indicators. SPSS 20.0 software was used for the chi-square test and multivariate logistic regression analysis. Results: The prevalence of total dyslipidemia (39.27%), hypertriglyceridemia (22.61%), and high LDL-C (6.03%) were the highest among those exposed to daily secondhand smoke. Among the male respondents, the prevalence of total dyslipidemia (44.42%) and hypertriglyceridemia (26.12%) were the highest among those exposed to secondhand smoke daily. Multivariate logistic regression analysis after adjustment for confounding factors showed that compared with no exposure to secondhand smoke, the population with an average exposure frequency of 1-3 days per week had the highest risk of total dyslipidemia (OR=1.276, 95%CI: 1.023-1.591). Among the patients with hypertriglyceridemia, those exposed to secondhand smoke daily had the highest risk (OR=1.356, 95%CI: 1.107-1.661). Among the male respondents, those exposed to secondhand smoke for 1-3 days per week had a higher risk of total dyslipidemia (OR=1.366, 95%CI: 1.019-1.831), and the highest risk of hypertriglyceridemia (OR=1.377, 95%CI: 1.058-1.793). There was no significant correlation between the frequency of secondhand smoke exposure and the risk of dyslipidemia among female respondents. Conclusions: Secondhand smoke exposure in Beijing adults, especially men, will increase the risk of total dyslipidemia, especially hyperlipidemia. Improving personal health awareness and minimizing or avoiding exposure to secondhand smoke is necessary.

Estimating elemental composition of personal PM2.5 by a modeling approach in two megacities, China

Personal exposure to PM2.5, and the elemental composition therein, may vary greatly from ambient measurements at fixed monitoring sites. Here, we characterized the differences between personal, indoor, and outdoor concentrations of PM2.5-bound elements, and predicted personal exposures to 21 PM2.5-bound elements. Personal-indoor-outdoor PM2.5 filter samples were collected for five consecutive days across two seasons from 66 healthy non-smoking retired adults in Beijing (BJ) and Nanjing (NJ), China. Personal element-specific models were developed using liner mixed effects models and evaluated by R2 and root mean square error (RMSE). The mean (SD) concentrations of personal exposures varied by element and city, ranging from 2.5 (1.4) ng/m3 for Ni in BJ to 4271.2 (1614.8) ng/m3 for S in NJ. Personal exposures to PM2.5 and most elements were significantly correlated with both indoor and outdoor (except Ni in BJ) measurements, but frequently exceeded indoor levels and fell below outdoor levels. Indoor and outdoor PM2.5 elemental concentrations were the strongest determinants of most personal elemental exposures, with RM2 ranging from 0.074 to 0.975 for indoor and from 0.078 to 0.917 for outdoor levels, respectively. Home ventilation conditions (especially window opening behavior), time-activity patterns, meteorological factors, household characteristics, and season were also key factors influencing personal exposure levels. The final models accounted for 24.2 %–94.0 % (RMSE: 0.135–0.718) of the variance in personal PM2.5 elemental exposures. By incorporating these crucial determinants, the modeling approach used here can improve PM2.5-bound elemental exposure estimates and better associate compositionally dependent PM2.5 exposures and health risks.

Incidence and characteristics of aspiration pneumonia in adults in Beijing, China, 2011–2017

ObjectivesThis study aimed to estimate aspiration pneumonia (AP) incidence and describe comorbid characteristics and mortality in Beijing, China. Study designA historical cohort study was conducted based on medical claim records. MethodsPatients admitted with a primary diagnosis of AP were identified from approximately 12 million adults who enrolled in the Urban Employee Basic Medical Insurance program in Beijing, China, from January 2011 to December 2017. The incidences of AP and pneumonia with risk factors for aspiration (PRFA) were estimated by a Poisson distribution. The estimated annual percentage change was reported to represent the average percentage change in incidence per year. Characteristics and 6-month and 1-year all-cause mortality rates for AP and suspected AP patients were described and compared with community-acquired pneumonia (CAP). ResultsThe incidence rates of hospitalized AP and PRFA were 9.4 (95% confidence interval [CI]: 7.6, 11.3) and 102.9 (95% CI: 95.8, 110.3) per 100,000 person-years, respectively. The incidences increased rapidly with age and were stable across the observed years. Patients with AP and PRFA possessed a greater burden of comorbidities than CAP (mean age-adjusted Charlson comorbidity indices for AP: 7.72, PRFA: 7.83, and CAP: 2.84). The 6-month and 1-year all-cause mortality rates for those with AP and PRFA were higher than those for patients with CAP (6-month mortality, AP: 35.2%, PRFA: 21.8%, CAP: 11.1%; 1-year mortality, AP: 42.7%, PRFA: 26.6%, CAP: 13.2%). ConclusionsThe incidence of AP and PRFA in Beijing was reported, presenting a full picture of the disease burden. The results provide baseline information for AP prevention.

Barriers and facilitators of family doctor contract services in caring for disabled older adults in Beijing, China: a mixed methods study

ObjectiveTo evaluate the current state of family doctor contract services (FDCS) in Beijing, identify the roles of family doctors who have worked with disabled older adults and investigate the barriers...

Cardiovascular effects of wearing respirators against particulate matter: A randomized crossover trial

Fine particles (PM2.5) are implicated as an important risk to cardiovascular health. N95 respirators had been widely used to provide protection by filtering particles. Yet the practical effects of wearing respirators have not been fully understood. This study aimed to evaluate the cardiovascular effects of respirator wearing against PM2.5 and underpin the understanding of the mechanisms of cardiovascular responses triggered by PM2.5. We conducted a randomized, double-blind crossover trial among 52 healthy adults in Beijing, China. Participants were exposed to outdoor PM2.5 for 2 h in alterations wearing true respirators (with membranes) or sham ones (without membranes). We measured ambient PM2.5 and tested the filtration efficiency of the respirators. We compared the heart rate variability (HRV), blood pressure and arterial stiffness indicators between the true respirator group and the sham respirator group. Concentrations of ambient PM2.5 during the 2-h exposure ranged from 4.9 to 255.0 μg/m3. The filtration efficiency of true respirators was 90.1 % and that of sham ones was 18.7 %. Between-group differences varied by pollution levels. On less polluted days (PM2.5< 75 μg/m3), participants wearing true respirators showed lower levels of HRV and higher levels of heart rate compared with those wearing sham respirators. These between-group differences were inconspicuous on heavily polluted days (PM2.5≥ 75 μg/m3). We found that a 10 μg/m3 increase in PM2.5 was associated with a 2.2 % to 6.4 % decrease in HRV, prominent at 1 h after the start of exposure. N95 respirators have good performance in reducing PM2.5 exposure. Short-term exposure to PM2.5 can induce very acute responses in autonomic nervous function. However, the overall effects of wearing respirators might be not always favorable to human health in terms of their inherent adverse effects, which seem dependent on the levels of air pollution. Precise individual protection recommendations warrant to be developed.

Association between oral health behavior and chronic diseases among middle-aged and older adults in Beijing, China

ObjectivesTo evaluate the association between oral health behavior and multiple chronic diseases among middle-aged and older adults.MethodsWe obtained data of the Beijing Health Service Survey and used multivariate logistic models to estimate the association between oral hygiene behavior and the risk of chronic diseases.ResultsThe risk of any chronic diseases (OR = 1.27, 95% CI: 1.18–1.37), cardiovascular diseases (CVD, OR = 1.30, 95% CI: 1.21–1.39), and endocrine or nutritional metabolic disorders (OR = 1.11, 95% CI: 1.01–1.22) was higher in those who with poor oral health behavior. There was no significant correlation between oral health behavior and the risk of diseases of the musculoskeletal, respiratory, digestive, and genitourinary systems.ConclusionsPoor oral hygiene practices were associated with higher risk of chronic diseases, CVD and diabetes mellitus (DM) among middle-aged and older adults. These findings motivate further studies to evaluate whether improved oral health behavior may prevent the incidence of chronic diseases.

Behaviors of Water Intake, Hydration Status, and Related Hydration Biomarkers among Physically Active Male Young Adults in Beijing, China: A Cross-Sectional Study.

Studies on the water intake of athletes in daily life are insufficient. The objective was to determine the water intake and hydration status among physically active male young adults. In this cross-sectional studies study, 111 physically active male young adults were recruited. The amount of daily total drinking fluid intake (TDF) among participants was recorded and evaluated in real time over 7 days using the "7-day 24-hour fluid intake questionnaire" (liq. In 7). The daily water intake from food (WFF) was calculated using the weighing, duplicate portion, and direct-drying method over 3 days. All urine samples over 3 days were collected, and urine biomarkers were determined. According to 24 h urine osmolality, the participants were divided into three groups with euhydration status, middle hydration, and hypo hydration statuses. Finally, 109 participants completed the study. The median daily total water intake (TWI), TDF, and WFF were 2701, ik1789, and 955 mL, respectively. Among participants, 17 participants (16%) were in euhydration status, 47 participants (43%) were in hypohydration, and 45 participants (41%) were in middle hydration. There were statistical significances in the 24 h urine volume, osmolality, urine specific gravity, and concentrations of K, Na, and Cl in different hydration statuses (χ 2 = 28.212, P < 0.01; χ 2 = 91.341, P < 0.01; χ 2 = 47.721, P < 0.01; χ 2 = 41.548, P < 0.01; χ 2 = 46.863, P < 0.01; and χ 2 = 40.839, P < 0.01). Moderate-intensity correlations were found between the TDF and 24 h urine volume, 24 h urine osmolality, 24 h urine Na concentration, morning urine osmolality, and morning urine Na concentration (r = 0.408, P < 0.01; r = -0.378, P < 0.01; r = -0.325, P < 0.01; r = -0.344, P < 0.01; and r = -0.329, P < 0.01). There were also moderate-intensity correlations between the TDF and 24 h urine osmolality, morning urine osmolality, and morning urine Na concentration (r = -0.365, P < 0.01; r = -0.371, P < 0.01; and r = -0.322, P = 0.01). Increased and higher moderate-intensity correlations were found between plain water and 24 h urine volume, 24 h urine osmolality, 24 h urine K and Na concentration, morning urine osmolality, and morning urine Na concentration (r = 0.374, P < 0.01; r = -0.520, P < 0.01; r = -0.312,P < 0.01; r = -0.355, P < 0.01; r = -0.446, P < 0.01; and r = -0.378, P < 0.01). Insufficient water intake and hypohydration were common among physically active male young adults. The amount and type of water intake were correlated with hydration status and urine biomarkers. The results could provide scientific and accurate references for the development of recommendations on water intake for athletes.

Attitudes towards dementia among Chinese adults aged 50 years and older: a comparative study of immigrants living in Melbourne and nonimmigrants living in Beijing.

This study investigated attitudes towards dementia among Chinese immigrants aged 50 years and over living in Australia and compares these attitudes with those of individuals living in mainland China. It aimed to better understand what older Chinese adults think about dementia and to inform the development of tailored dementia-related services for this group of people. A qualitative design involving individual interviews was employed in this study. Forty-six participants were recruited: 21 in Melbourne and 25 in Beijing. All interviewees were born in mainland China, were community-dwelling, and did not have a dementia diagnosis. The tripartite model of attitudes was used to guide the semi-structured interview design and report the results. Thematic qualitative analysis was employed. In both groups, most participants held negative feelings, stigmatized views and negative stereotypes of dementia. However, most participants expressed a willingness to help individuals living with dementia. Regarding dementia care, nearly all participants preferred home care but thought formal care would become the mainstream form of care in the future. Fewer Melbourne participants expressed concerns regarding developing dementia, were interested in dementia, or perceived a need for dementia-related educational activities. Melbourne participants also reported more avoidant responses to dementia or individuals living with dementia. This study carefully compares attitudes towards dementia between older Chinese immigrants in Melbourne and older Chinese adults in Beijing. Similarities and differences were observed between these two groups. Dementia-related service providers should consider the sociocultural changes and migration-related barriers experienced by Chinese immigrants.

Association between neighborhood food environment and dietary diversity score among older people in Beijing, China: A cross-sectional study.

ObjectiveTo examine the association between the neighborhood food environment and dietary diversity score (DDS) among elderly people in China.MethodsParticipants were recruited from 12 communities in Beijing, China, in 2019, using a multi-stage stratified random sampling method. Participants (n = 1,764, 730 men) in this study were elderly people aged 65 to 80. A questionnaire survey was used to investigate the intake of various foods in the past 3 days, and their dietary diversity score (DDS) was calculated. Baidu Map Application Programming Interface was used to measure the neighborhood food environments, including the density of and proximity to different food outlets. Adjusted multiple linear regression was performed to estimate the association between the neighborhood food environment and DDS.ResultsA total of 1,800 questionnaires were distributed, and 1,775 questionnaires were returned. The questionnaire response rate was 98.6%. Among them, the number of valid questionnaires was 1,764, and the valid rate was 99.4%. The mean age of the participants was 69.7 ± 4.3, and the average DDS was 7.2 ± 1.4. Among the three types of stores, convenience stores had the best access, followed by greengrocers, and finally supermarkets. Sit-down restaurants had the nearest walking distance, Chinese fast-food restaurants had the largest number, and western fast-food restaurants were the most difficult to access. Better access to supermarkets tended to be associated with higher DDS score within all the buffer zones (250 m buffer zone: β = 0.495, P < 0.001; 500 m buffer zone: β = 0.341, P < 0.001; 800 m buffer zone: β = 0.163, P < 0.001; 1,000 m buffer zone: β = 0.243, P < 0.001). However, greengrocers were negatively associated with DDS score within all the buffer zones (250 m buffer zone: β = −0.475, P < 0.001; 500 m buffer zone: β = −0.161, P < 0.001; 800 m buffer zone: β = −0.090, P < 0.001; 1000 m buffer zone: β = −0.112, P < 0.001). As for convenience stores, we only found significant results within the 250 m buffer zone (β = 0.075, P = 0.002). Among the three types of restaurants, the results were inconsistent within different buffer zones. Sit-down restaurants were negatively associated with DDS score within 250 m buffer zone (β = −0.257, P < 0.001), and positively associated with DDS score within 1,000 m buffer zone (β = 0.018, P < 0.001). Living in areas with more Chinese fast-food restaurants tended to have higher DDS within 250 m buffer zone (β = 0.357, P < 0.001); however, there was a opposite result within 1,000 m buffer zone (β = −0.044, P < 0.001). Better access to western fast-food restaurants tended to be associated with lower DDS score within 500 m buffer zone (β = −0.235, P < 0.001) and higher DDS score within 1,000 m buffer zone (β = 0.189, P < 0.001). There was a negative correlation between the nearest distance to the supermarket and the DDS score (β = −0.002, P < 0.001), and the nearest distance to the greengrocer was directly positively correlated with the DDS score (β = 0.004, P < 0.001).ConclusionThis study suggests that supermarkets may increase the DDS score among older adults in Beijing, while greengrocers may reduce the DDS score. However, the current results are not strong enough to draw specific conclusions. Policymakers need to rely on more evidence to make specific policy recommendations.

Residential green space, air pollution, public facility and mortality among older adults in Beijing: a longitudinal cohort study

Residential green space, air pollution, public facility and mortality among older adults in Beijing: a longitudinal cohort study