Adolescent Weight Research Articles

Dosing of antidepressants in relation to body weight in children and adolescents with overweight.

Overweight and obesity in children and adolescents may impact pharmacokinetics and drug exposure. The aim of the present study was to evaluate doses of antidepressants in relation to body weight in children. We used data from the BMI Epidemiology Study (BEST) Gothenburg cohort and the National Prescribed Drug Register and included children and adolescents with a prescription of fluoxetine (n = 347) or sertraline (n = 733) and a weight measurement. For fluoxetine, individuals with overweight or obesity received slightly lower doses at first prescriptions, but not in iterated prescriptions. The weight-normalized dose was lower in individuals with overweight or obesity in first and iterated prescriptions, compared with normal weight (p < 0.01). For sertraline, there were no significant dose differences between individuals with overweight or obesity, compared with normal weight. However, pronounced differences were seen in dose per kilogram body weight in both first and iterated prescriptions (p < 0.01). We conclude that the doses of fluoxetine and sertraline were essentially similar in individuals with overweight or obesity, but the weight-normalized doses were clearly lower. Given the ongoing obesity epidemic, larger studies addressing optimal dosing in individuals with elevated weight are warranted.

Insomnia severity and obesity mediated by health behaviors in adolescents.

Sleep difficulties in youth have been associated with numerous negative outcomes, such as higher risk of obesity. Though the relationship between sleep and obesity is not well clarified, past research has shown that modifiable health behaviors, such as diet, physical activity, and screen time, may explain this relationship. The purpose of this study was to simultaneously examine these health behaviors as mediators of the relationship between insomnia severity and obesity among a sample of adolescents aged 12-18years. English-speaking parents/legal guardians of adolescents were invited to participate in an online survey focused on pediatric sleep patterns, health behaviors, and weight. Parents/guardians (N = 599) reported on their adolescent's diet (i.e., consumption of fruits/vegetables, fast food, and breakfast), physical activity, screen time, and BMI. A multiple mediation analysis was run to test these health behaviors as mediators of the relationship between insomnia severity and BMI, after controlling for sex, age, race, and poverty. While insomnia was related to most health behaviors, screen time was the only significant mediator of the relationship between insomnia and BMI, after controlling for the effects of the other mediators and all covariates, ab = .04, 95% CrI [.01, .09]. Screen time has implications for both adolescents' sleep health and weight. Pediatric clinicians should systematically assess for, and provide, recommendations on ways to improve sleep and screen time use, in addition to providing traditional dietary and physical activity recommendations.

The association of adolescent to midlife weight change with age at natural menopause: a population study of 263,586 women in Norway.

Age at menopause varies considerably among women and is linked to health after menopause. Body mass index is associated with age at natural menopause, but the influence of weight change remains unclear. Thus, we studied associations of adolescent to midlife weight change with age at natural menopause. We performed a retrospective population-based cohort study of 263,586 women aged 50-69 years attending BreastScreen Norway (2006-2015). The associations were estimated as hazard ratios (HRs) for having reached menopause using Cox proportional hazard models. We included nine categories of weight change based on recalls of adolescent weight compared to peers and quartiles of midlife weight in kilograms. We adjusted for year and country of birth, education, number of childbirths, height, smoking, and exercise. Women with the largest estimated weight loss had highest hazard of reaching menopause (adjusted HR 1.11, 95% CI: 1.06-1.17) compared to women with estimated stable average weight. Conversely, women with the largest estimated weight gain had lower hazard (adjusted HR 0.96, 95% CI: 0.93-0.99). Women with estimated stable high weight had lowest hazard of reaching menopause (adjusted HR 0.93, 95% CI: 0.90-0.95). Our findings suggest that changes in body weight across the life course may influence the timing of menopause.

Exploring the association between low birthweight and adolescent mental health in the United Kingdom

Abstract Low birthweight (LBW) is associated with a range of medical conditions including behavioural and emotional problems over the life course. This study aimed to explore the association between LBW and internalising and externalising mental health problems (MHP) in adolescents born in the United Kingdom between 2000 and 2002. Data were analysed for 10,485, 9,228, and 8,402 Millennium Cohort Study participants at ages 11, 14 and 17, respectively. Internalising and externalising MHP were measured using the Strengths and Difficulties Questionnaire (SDQ). LBW was subcategorised by size for gestational age and prematurity. Crude and adjusted associations between LBW subgroup and internalising and externalising MHP were estimated using binary logistic regression. Internalising MHP were more prevalent in LBW than NBW participants at ages 11 (14.2% vs 10.3%, p &amp;lt; 0.001), 14 (19.4% vs 13.7%, p &amp;lt; 0.001), and 17 (parent-report: 20.3% vs 14.8%, p &amp;lt; 0.001; self-report: 25.7% vs 20.1%, p &amp;lt; 0.001), respectively. Externalising MHP were more common amongst LBW participants at ages 11 (9.4% vs 7.3%, p = 0.02) and 14 (9.0% vs 6.6%, p = 0.01). Compared with NBW peers, the odds of internalising (males: aOR 2.18, 95% CI 1.21-3.73, p = 0.007; females: aOR 2.17, 95% CI 1.22-3.66, p = 0.005) and externalising MHP (males: aOR 2.01, 95% CI 1.05-3.60, p = 0.014; females: aOR 2.58, 95% CI 1.14-5.24, p = 0.016) were significantly increased in male and female premature small for gestational age (SGA) participants at age 11. Externalising MHP were significantly increased amongst premature SGA females aged 14 (aOR: 2.53, 95% CI 1.01-5.66, p = 0.016). Internalising MHP were significantly increased in premature SGA females at age 17 based on parent (aOR: 2.41, 95% CI 1.38-4.22, p = 0.005) and self-report (aOR: 1.95, 95% CI 1.14-3.31, p = 0.014). Amongst LBW individuals, premature SGA females have the greatest risk of internalising and externalising MHP during adolescence, thus identifying an important target group for intervention. Key messages • This study provides evidence for the longitudinal association between low birth weight and mental health in adolescents born in the United Kingdom in the 21st century. • Stratification of low birth weight individuals by size for gestational age and prematurity enabled the identification of a subgroup of adolescents for mental health promotion.

Exploring the impact of stimulant medications on weight in children with attention deficit hyperactivity disorder in Dubai, United Arab Emirates.

Attention deficit hyperactivity disorder (ADHD), prevalent in 5% of children worldwide, impacts academic performance and often coexists with psychiatric disorders. Psychostimulant medications are primary treatments for ADHD, enhancing dopamine to reduce symptoms. However, dopamine increase may cause appetite loss. This pioneering study in the United Arab Emirates (UAE) explores psychostimulant effects on weight in children diagnosed with ADHD, aiming to uncover unique regional characteristics and contributing factors to weight changes. This retrospective cohort study assessed data from electronic medical records from 2017 to 2022, aiming to assess the impact of psychostimulants on weight in children aged 6-18 years. Inclusion criteria covered psychostimulant-treated and untreated patients with ADHD. Statistical analysis, involving longitudinal data methods aimed to demonstrate significant weight differences. Data from 107 pediatric patients diagnosed with ADHD were analyzed, with 86 meeting inclusion criteria. Most patients were male (80.2%). ADHD presentations varied, and methylphenidate immediate release was the most prescribed stimulant medication. Patients experienced initial weight loss followed by overall gain over 12 months. Coexisting conditions, maternal factors, family history, and correlations with autism spectrum disorder were explored. This study provides valuable insights into the effects of psychostimulant medications on the weight of children and adolescents diagnosed with ADHD in the UAE. It suggests avenues for future research, emphasizing extended follow-ups to understand long-term psychostimulant effects, nuanced examinations of age and gender, and exploring interactions with comorbidities. Despite limitations, the research provides insights into ADHD medication effects, guiding personalized treatment approaches for pediatric populations.

5174 A longitudinal retrospective cohort study on the application of the Superimposition by translation and rotation (SITAR) model to estimate body composition growth trajectory in Korean children and adolescents during puberty

Abstract Disclosure: S. Kim: None. S. Kim: None. J. Suh: None. Introduction: In addition to adulthood, pediatricians have noted a growing emphasis on research concerning sarcopenic obesity. Studies in this field have expanded beyond basic BMI-related inquiries, actively delving into investigations based on body fat mass (BFM) and fat-free mass (FFM). However, limited research has systematically analyzed the acquisition of body composition during children and adolescence based on longitudinal data. Objective: This study aims to assess the acquisition of weight, FFM, and BFM during the pubertal growth of Korean children and adolescents. Methods: This study utilized mixed longitudinal body measurement and body composition data, employing bioelectrical impedance analysis, from 4,641 height measurements (2,204 for boys and 2,437 for girls) obtained from 361 individuals (170 boys and 191 girls) among Korean children and adolescents aged 7 to 18. The SITAR (the Superimposition by Translation and Rotation) model, a shape-invariant growth curve model, was used to estimate a reference height velocity curve during pubertal growth. Results: The SITAR methodology allowed us to investigate the timing, magnitude, and intensity of adolescent weight, FFM, and BFM gain. The results revealed significant differences in growth trajectories between boys and girls, with boys exhibiting a persistent elevation in FFM and a pattern of ascent followed by a decline in BFM, while girls show an increase in BFM and a deceleration in FFM growth. In Korean boys, the peak weight velocity (PWV) occurred at a mean age of 12.41 years, with a rate of 8.19 kg/year. Peak fat-free mass velocity (PFV) was observed at a mean age of 9.69 years, with a rate of 7.60 kg/year, and peak body fat mass velocity (PBV) at a mean age of 12.70 years, with a rate of 2.67 kg/year. In Korean girls, the mean age of PWV was 11.28 years, with a velocity of 6.33 kg/year. PFV occurred at a mean age of 12.33 years, with a rate of 4.86 kg/year, and PBV at a mean age of 11.13 years, with a rate of 2.72 kg/year. The ages of peak velocities of height (PHV), PWV, PFV, and PBW positively correlated. Conclusions: This study is the first to apply the SITAR model to examine the acquisition of body composition in Korean children and adolescents. Future research should delve into exploring the connections between various disease groups during childhood and adolescence and the patterns of change in body composition. Presentation: 6/1/2024

Trends and inequalities in thinness and obesity among Chinese children and adolescents: evidence from seven national school surveys between 1985 and 2019.

There are little recent data in China regarding contemporary nutritional inequities among children and adolescents, particularly in relation to urban-rural residence and regional socioeconomic status (SES). We aim to assess inequalities in thinness and obesity in Chinese children and adolescents. Weight and height measurements for 1 677 261 children and adolescents aged 7-18 years were obtained from seven cycles of the Chinese National Surveys on Students Constitution and Health (1985, 1995, 2000, 2005, 2010, 2014, and 2019). Sex-specific BMI-for-age Z scores were applied to define thinness (Z scores <-2SD) and obesity (Z scores >+2SD). Urban-rural classification came from the Statistical Urban and Rural Division Code, and gross domestic product (GDP) per capita in the province in which the school was situated was used as a proxy for SES. T1 represented the provinces with the most disadvantaged SES and T3 represented the provinces with the most advantaged SES. General linear regression models assessed correlations between prevalence and GDP per capita, with projections to 2030 derived from best-fitting models. The mean prevalence of obesity rose from 0·10% (95% CI 0·09 to 0·11) in 1985 to 8·25% (8·13 to 8·37) in 2019, whereas thinness prevalence decreased from 8·49% (8·41 to 8·58) to 3·37% (3·29 to 3·45). High SES provinces exhibited a significant drop in obesity prevalence from 2014 (8·42% [8·19 to 8·65]) to 2019 (7·73% [7·52 to 7·95]). Nationally, the prevalence of obesity was consistently higher in urban areas than in rural areas for both sexes from 1985 to 2019; however, a greater prevalence of obesity was observed in rural than urban girls residing in T3 regions in 2019 (urban-rural gap: -0·37% [-0·07 to -0·80]). Rural boys had a higher prevalence of thinness than their urban counterparts across all survey waves, with the exceptions of 1985 and 1995. For girls, no significant urban-rural gap in thinness was observed in the most recent survey in 2019 (-0·10% [-0·24 to 0·04]). From 1985 to 2014, boys and girls from high SES regions had a higher risk of obesity and a lower risk of thinness than those from low SES regions. However, in 2019, a nationwide shift occurred, and the T3-T1 difference in obesity approached or went below zero for boys (-0·49% [-1·02 to 0·04]) and girls (-0·68% [-1·00 to -0·35]). T3-T1 differences in thinness also approached zero for boys (-0·46% [-0·77 to -0·14]) and girls (-0·14% [-0·43 to 0·15]). The projected estimates to 2030 for urban-rural obesity gaps (boys: -1·00% [-2·65 to 0·65]; girls: -2·88% [-6·91 to 1·15]) and T3-T1 obesity differences (boys: -8·88% [-13·76 to -4·01]; girls: -8·82% [-12·78 to -4·85]) were both negative, with forecasted estimates for urban-rural gaps and T3-T1 differences in thinness prevalence in 2030 close to zero for both boys and girls. China's socioeconomic development continues to influence within-country inequities regarding the regional distribution of child and adolescent weight according to urban-rural location and regional SES. Contemporary Chinese children and adolescents in socioeconomically disadvantaged regions and rural areas constitute a vulnerable population facing nutritional risk, but from obesity rather than thinness. Disrupting projected inequities in obesity will require extensive preventive investments. National Natural Science Foundation of China, Beijing Natural Science Foundation, Peking University Talent Introduction Program Project, and Clinical Medicine Plus X-Young Scholars Project of Peking University. For the Chinese translation of the abstract see Supplementary Materials section.

Potential effects of attention deficit hyperactivity disorder medication on body height and body weight in a longitudinal pediatric cohort study, the LIFE Child study.

Purpose: To investigate the potential impact of drugs for the treatment of attention deficit hyperactivity disorder (ADHD) on body weight and height in children and adolescents from the LIFE ('Leipzig Research Centre for Civilization Diseases', Leipzig, Germany) Child cohort. Methods: We included 2,115 participants aged ≥6 to <18.25 years who attended the LIFE study center between 2011 and 2020 in our analysis, of whom 48 used ADHD drugs. Anthropometric and medication data from baseline to the third follow-up visit were available for 659 participants. Body height and body weight measurements were subsequently converted to z-scores. A repeated measures analysis of variance (ANOVA) was performed on the z-scores of both ADHD drug users and non-users to determine potential trends in body weight and body height from baseline to the 3 rd annual follow-up. Results: At the last visit with ADHD drug use of the 48 ADHD drug users, 40% (19/48) of the children and adolescents were below the 25 th reference percentile for weight. Z-scores for body height declined from baseline to the 3rd annual follow-up in individuals who used ADHD drugs (n=10; Differencemeans =-0.310; p=0.002) compared to non-users (n=649; Differencemeans =0.102; p<0.001). Body weight also decreased from baseline to 3rd follow-up in the ADHD drug group (n=10; Differencemeans =-0.473; p<0.001) compared to the non-user group (n=649; Differencemeans =0.015; p=0.161). Conclusion: We observed a potential tendency towards lower Z-scores for body height and body weight in individuals taking ADHD medication for an extended period compared to the corresponding age- and sex-matched populations.

Pediatrics hyperuricemia in clinical practice: A retrospective analysis in 1753 children and adolescents with hyperuricemia

ObjectivesSerum levels of uric acid (S-UA) are influenced by the interaction of genetic and environmental factors; detailed studies of hyperuricemia in children are rare. This retrospective study aimed to analyze the causes, risk factors, and therapeutic approaches associated with the development of hyperuricemia in childhood. MethodsIn a single-center study, serum uric acid levels were analyzed in 33,900 samples from 13,890 children and adolescents˂19 years (6760 girls and 7130 boys) obtained between 2013 and 2023. Hyperuricemia was defined as S-UA>370μmol/L (6.22mg/dL) in girls and>420μmol/L (7.06mg/dL) in boys; mild hyperuricemia was defined as 370–420μmol/L in boys˂13 years. ResultsIn the analyzed group, hyperuricemia was found in 1753 patients (12.6%), including 586 girls and 864 boys; mild hyperuricemia was found in 303 boys˂13 years. The most common associated conditions were obesity with body mass index>95th percentile (27.8% of girls, 26.3% of boys) and chronic kidney disease (18.6% of boys, 11.4% of girls). Hyperuricemia was also relatively common in children with connective tissue disorders (10.6%) or different inherited metabolic disorders (10.7%). Transitory hyperuricemia was found in 19.1% of girls and 10.1% of boys with acute gastroenteritis. Urate-lowering therapy was used in 73 children and adolescents with severe hyperuricemia (S-UA 556±107μmol/L, fraction excretion of UA 3.27±1.98%). Eight treated children had chronic kidney disease, nine were extremely obese, one had combined antiepileptic therapy, and 55 had inherited metabolic diseases, including 26 children with disorders of purine metabolism. The initial daily dose of allopurinol (50–100mg) normalized the S-UA (350±80μmol/L) in a majority of children, except for extremely obese adolescents (weight 98–149kg) where the dose had to be increased to 200–300mg. ConclusionsAsymptomatic hyperuricemia is a relatively common biochemical finding in pediatric clinical practice. The etiology of hyperuricemia should be carefully analyzed, and the value of individualized hyperuricemia management and the eventual benefits of urate-lowering therapy in children must be carefully considered.

You Code It! Answers: Adolescent Weight Loss Due to a Suspected Eating Disorder (Online Exclusive)

Did you correctly code this month’s You Code It! scenario? Find out here.

You Code It! Adolescent Weight Loss Due to a Suspected Eating Disorder

In this coding challenge, the patient is a 12-year-old who presents to a primary care pediatrician due to parental concerns of an eating disorder. Can you assign appropriate diagnosis and procedure codes for the illness and services provided in 2 distinct settings in this scenario?

Effects of physical training on body weight, pulmonary function and dietary patterns in adolescents with obesity

Physical activity offers a powerful tool to address the challenges faced by obese teenagers. By promoting social inclusion, improving physical health, and boosting mental well-being, sports can significantly enhance their overall quality of life. Our research discusses the negative effects of obesity in adolescents and the benefits of a sports program when addressing these issues. The study involved 60 participants (30 males and 30 females) aged 14-16 for a period of eight months. Results showed significant weight loss for most participants: 26 participants lost around 10% of their body weight, another group lost around 8%, and only 4 subjects did not experience significant weight change. The study also observed a 9.5% improvement in motor skills on average. The mean weight loss difference between intervention and control was 9.30%. The study emphasizes the detrimental effects of obesity in adolescents and highlights the effectiveness of physical activity programs in promoting weight loss, enhancing respiratory function and induce healthy eating habits among obese adolescents. It also underscores the positive social and lifestyle benefits associated with regular physical activity. Keywords: physical activity; obesity; exercise; inclusion; nutrition

Prevalence of overweight and obesity, and associations with socio-demographic and etiological factors

Background: Adolescent obesity and overweight (OW) prevalence are rising quickly. The present study was done to assess the prevalence of OW and obesity and its association with demographic and etiological factors. Methods: An observational study including 386 adolescents aged 10-19 years was conducted using a pre-designed questionnaire. Anthropometric measurements of weight (kg) and height (cm) were taken and body mass index (BMI) calculated by weight (kg)/height2(m2). The weight status was classified as underweight (UW) &lt;5th percentile, healthy weight (HW) between the 5th and &lt;85th percentile, OW between &gt;85th and &lt;95th percentile, and obese (OB) equal to or &gt;95th percentile using the CDC percentile ranking for BMI-for-age. Statistical data analysis was done by SPSS software version 20. P&lt;0.05 was considered significant. Results: The mean age of adolescents in early, mid, and late adolescent age groups were 11.52 (1.13), 15.01 (0.82), and 17.72 (0.77) years respectively. The overall mean age of adolescents was 14.19 (2.63) years. The mean weight, height, and BMI of adolescents were 44.84 (11.35) kg, 1.54 (0.12) meters, and 18.91 (3.89) kg/m2 respectively. The prevalence of OW and obesity was 11.7%, and 5.4% respectively. A significant association was found between OW and obesity with upper socioeconomic status (p&lt;0.0001), daily junk food intake (p&lt;0.0001), screen time of more than 2 hours per day (p&lt;0.0001), and no or decreased physical activity (p&lt;0.0001). Conclusions: Adolescent obesity is a prevalent issue that requires early primordial and primary intervention through coordinated policy activities made by policymakers and medical professionals.

Robust identification key predictors of short- and long-term weight status in children and adolescents by machine learning.

Early identification of high-risk individuals for weight problems in children and adolescents is crucial for implementing timely preventive measures. While machine learning (ML) techniques have shown promise in addressing this complex challenge with high-dimensional data, feature selection is vital for identifying the key predictors that can facilitate effective and targeted interventions. This study aims to utilize feature selection process to identify a robust and minimal set of predictors that can aid in the early prediction of short- and long-term weight problems in children and adolescents. We utilized demographic, physical, and psychological wellbeing predictors to model weight status (normal, underweight, overweight, and obese) for 1-, 3-, and 5-year periods. To select the most influential features, we employed four feature selection methods: (1) Chi-Square test; (2) Information Gain; (3) Random Forest; (4) eXtreme Gradient Boosting (XGBoost) with six ML approaches. The stability of the feature selection methods was assessed by Jaccard's index, Spearman's rank correlation and Pearson's correlation. Model evaluation was performed by various accuracy metrics. With 3,862,820 million student-visits were included in this population-based study, the mean age of 11.6 (SD = 3.64) for the training set and 10.8 years (SD = 3.50) for the temporal test set. From the initial set of 38 predictors, we identified 6, 9, and 13 features for 1-, 3-, and 5-year predictions, respectively, by the best performed feature selection method of Chi-Square test in XGBoost models. These feature sets demonstrated excellent stability and achieved prediction accuracies of 0.82, 0.73, and 0.70; macro-AUCs of 0.94, 0.86, and 0.83; micro-AUCs of 0.96, 0.93, and 0.92 for different prediction windows, respectively. Weight, height, sex, total score of self-esteem, and age were consistently the most influential predictors across all prediction windows. Additionally, several psychological and social wellbeing predictors showed relatively high importance in long-term weight status prediction. We demonstrate the potential of ML in identifying key predictors of weight status in children and adolescents. While traditional anthropometric measures remain important, psychological and social wellbeing factors also emerge as crucial predictors, potentially informing targeted interventions to address childhood and adolescence weight problems.

Association of adolescent obesity with Anxiety, Depression and Attention-Deficit/Hyperactivity disorder in the Arab population in Israel - a nationwide study

BackgroundThe health ramifications of adolescent obesity are understudied in the Israeli Arab population, and the impact of ethnicity on the association of obesity with mental health problems is unclear. AimTo examine the association of weight categories with Anxiety, Depression and Attention-Deficit/Hyperactivity Disorder (ADHD) among Arab adolescents in Israel and to compare this association to a Jewish comparison group. MethodsA cross-sectional nationwide study of 313,936 Arab adolescents aged 14–19 years between the years 2007–2022, and 289,616 Jewish adolescents in a comparison group. ResultsThe aORs for Anxiety, Depression and ADHD in Arab adolescents increased from a reference ‘normal weight’ category to ‘class 3 obesity’, reaching aORs (95 % CI) of 1.31 (1.16–1.47), 1.64 (1.31–2.02) and 1.51 (1.40–1.63) in ‘class 2 obesity’, and 1.51 (1.20–1.87), 2.81(2.00–3.84) and 1.69 (1.45–1.96) in ‘class 3 obesity’, respectively. The dose-dependent association between weight categories and psychiatric comorbidity was confirmed in sensitivity analyses with comorbidity with the purchase of medications serving as the dependent variable. The Jewish comparison group demonstrated a comparable increment in aORs with increase in weight category. The association between excessive weight categories and psychiatric comorbidities was stronger in Arab females, than in males. LimitationsRelying on the recorded weight and height measurements and the diagnoses of psychiatric comorbidity could lead to bias. ConclusionThe study findings emphasize the need to relate to the mental health of adolescents with excessive weight, which can improve their overall quality of life and the success of adolescent weight loss intervention programs.

Family functioning and the implications for adult weight management.

Strong support for family-based interventions in child and adolescent weight management exists. However, family-based interventions have not been as well documented in adult populations. Given that many adults operate within family systems that could influence their weight management behaviors, research is needed to establish possible family-level variables as intervention targets for adult weight loss programs. This study tested the relationship between family functioning (defined as support and bonding), chaos (defined as disorder in the home), and weight loss in adults with overweight or obesity participating in a behavioral weight-loss program. Participants (N = 118; baseline mean body mass index 33.8 ± 3.7; 69.5% female; 97.5% White; 67.8% with a combined annual income of $75k or above; 90.7% completed some college or above) were from a randomized controlled trial examining weight loss ripple effects (Gorin et al., 2018) in individuals assigned to either 6 months of WW (formerly Weight Watchers) or a self-guided approach. Higher family support and bonding at baseline were associated with greater percent weight loss at 6 months. Family support and bonding at baseline were associated with lower chaos in the home at 6 months. However, this was moderated by condition such that this association was significant in the WW but not the self-guided group. Results provide theoretical support that targeting family dynamics may improve weight loss outcomes in behavioral weight loss programs for adults. Future research should test whether family support, bonding, chaos, or other related variables such as family cohesion and adaptability-focused interventions improve weight loss outcomes for adults. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

236 - Unpacking adolescent weight management interventions: a synthesis of delivery features and behaviour change strategies

236 - Unpacking adolescent weight management interventions: a synthesis of delivery features and behaviour change strategies

Shared human papillomavirus vaccine readiness within families: A psychometric analysis of parent-adolescent dyads in France.

In France, uptake of the recommended human papillomavirus (HPV) vaccination remains low. The vaccine cannot be administered without parental consent, but studies have shown that adolescents can make informed decisions about their health. We aimed at understanding the weight of adolescents' vaccination intention in parents' vaccination decision, using data from parent-adolescent dyads collected at baseline of a randomized trial of vaccine promotion interventions. About 649 parent-adolescent dyads from 61 middle schools in France independently completed an online questionnaire on their knowledge and attitudes toward HPV vaccination, structured around the seven psychological domains of vaccine readiness (VR). We used multivariate and path analyses to understand the family decision-making process. HPV vaccination was reported by 50.1% of adolescents and 45.5% of parents. Individual antecedents of VR were poorly correlated within dyads (r = .14-.36). Vaccine intentionality among parents of girls depended both on their own VR (β = .53, p < .001) and on their daughters' vaccine intention (β = .25, p < .001). But among parents of boys, vaccine intention depended only on their own VR (β = .72, p < .001). Adolescents' VR depended more strongly on the social environment's attitude among boys than among girls (β = .54 vs. .34, p < .01). The defined model showed shared decision processes between parents and adolescent girls, but not boys, which can be understood in the context of a recent expansion of HPV vaccination to boys. Beyond this, it suggests that promotion targeting adolescents and their social environment can have a positive influence on parental intentions. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

The influence of COVID-19 pandemic on body mass and cardiopulmonary endurance of Chinese adolescents: a longitudinal follow-up study.

With the spread and spread of COVID-19 around the world, youth's learning, lifestyle and health have been greatly affected. Based on the current research, there is no adequate analysis of the development of young people's physique and heart and lung health during COVID-19, and there is a lack of relevant targeted research. The aim of this study was to investigate the changes of BMI and Maximum Oxygen Absorption (VO2max) in 12-14 year old teenagers before and after COVID-19. The BMI, 1,000/800 m running time and associated data related to 29,813 individuals between 2019 and 2022 were collected by cluster sampling, and the changes of BMI Z and VO2max before and after the outbreak were analyzed. Moreover, the relationship between BMI and cardiovascular endurance was analyzed by means of multi-linear stepwise regression. The covariance analysis models indicated that compared with 2019, adolescent weight, BMI, and 1,000/800 m running time showed varying degrees of growth in 2020, while lung capacity decreased. All indicators achieved rapid rebound in 2021 and 2022 (p < 0.01); the one-way analysis of variance models indicated that The BMI Z score and VO2max of adolescents showed growth and decline in 2020, respectively, and achieved rapid recovery and development in 2021 and 2022 (p < 0.01). The results of the multiple linear stepwise regression analysis indicate that, after the years of BMI Z and novel coronavirus infection were included (△R2 = 0.179), adolescents' overweight and obesity were positively correlated with the maximum oxygen uptake (B = 0.643, 95%CI = 0.634 ~ 0.652); There is a negative correlation between weight loss and maximum oxygen uptake (B = -0.510, 95%CI = -0.537~-0.484); The year of novel coronavirus infection was positively correlated with the maximum oxygen uptake of adolescents (B = 0.116, 95%CI = 0.107~0.125). This study shows that the impact of COVID-19 on BMI and heart and lung health in adolescents is significant. Young people of all ages and sexes showed similar developmental trends.

Design of the FRESH-teen study: A randomized controlled trial evaluating an adapted emotion regulation weight loss program for adolescents with overweight or obesity and their parent

Overweight and obesity affect >40% of adolescents. Family-based behavioral treatment (FBT) is the most efficacious behavioral treatment for weight management among youth and consists of nutrition and physical activity education, behavior change skills, and parent skills training. However, the efficacy of FBT decreases for youth as they get older. Increased emotional lability and limited emotion regulation skills may contribute to the reduced efficacy of FBT for adolescents. To date, there are no treatments for overweight or obesity specifically adapted for the needs of adolescents.We developed a treatment that integrates components from Dialectical Behavior Therapy and Emotion Focused Therapy with FBT (FBT+ER or FBT-ER) to address the specific needs of adolescents. The current study randomized 166 adolescents (BMI = 32.8; 14.3 years; 57% female; 32% Hispanic, 50% Non-Hispanic White, 18% Non-Hispanic and Non-White) and one of their parents (BMI = 32.9; 45.3 years; 85% female; 27% Hispanic, 57% Non-Hispanic White, 16% Non-Hispanic and Non-White) to 6 months of either standard FBT or FBT+ at 2 sites. Assessments were conducted at baseline, mid-treatment (month 3), post-treatment (month 6), 6-month follow-up (month 12) and 12-month follow-up (month 18). Primary outcomes are adolescent weight (BMIz/%BMIp95), emotion regulation skills, and emotional eating behaviors. Given the public health concern of adolescent obesity, FBT+ could prove extremely useful to provide more targeted and effective intervention for adolescents with overweight or obesity. Clinical trials# NCT03674944