Adjacent Component Research Articles

Spatially resolved capacitance-based stress self-sensing in concrete

Spatially resolved capacitance-based stress self-sensing in unmodified concrete has been demonstrated. The spatial resolution is 45 mm in one dimension, which is in the direction of the capacitance measurement. Parallel coplanar component electrodes (aluminum, 5-mm wide), attached to the concrete using double-sided adhesive tape) separated by 45 mm are used to measure the in-plane capacitance in the direction perpendicular to the length of the electrodes. Combinations of component electrodes are electrically connected to form an electrode. The capacitance ranges from ∼200 pF to ∼750 pF. The greater is the number of component electrodes in an electrode, the higher is the capacitance. The compressive loading is applied at selected areas located between adjacent component electrodes. The stress (defined as load divided by the 300 ×300-mm2 concrete area) is up to 3000 Pa. The load decreases the capacitance monotonically and reversibly. The fractional decrease in capacitance ranges from ∼0.1 % to ∼0.5 %. More spatially concentrated loading, as for loading near the edges of the specimen, gives greater fractional decrease in capacitance. The capacitance decreases with increasing inter-electrode distance. Embedded steel rebars with a 20.0-mm concrete cover do not affect the capacitance or capacitance-based sensing.

Red emissive carbon dots Self-Cascading antioxidant nanozymes combine with anti-miRNA-155 for accurate monitoring and ameliorating rheumatoid arthritis

Accurate monitoring and effective antioxidant treatment strategies are highly desirable in rheumatoid arthritis (RA) amelioration. Herein, cerium (Ce) and selenium (Se) co-doped carbon dots (CS-CDs) integrated superoxide dismutase (SOD)-like and glutathione peroxidase (GPx)-like self-cascading catalytic activity are engineered. In this self-cascading nanozymes system, Ce active center catalyzes ·O2− to H2O2 by mimicking SOD, and the adjacent Se component sequentially decomposes the H2O2 by mimicking GPx, achieving enhanced catalytic and superior reactive oxygen species (ROS)-scavenging activities. CS-CDs further load cyanine-5 (Cy5)-labeled anti-miRNA-155 to realize macrophage subphenotype identification via miRNA-155 ratiometric imaging for RA accurate monitoring, and regulate the polarization of pro-inflammatory macrophages for synergistic RA amelioration. Comprehensive in vitro and in vivo experiments validate the advanced RA monitoring and therapy performance of the self-cascading nanozymes. This work not only offers a rationally designed self-cascading nanozyme with simple structures and intriguing ROS-scavenging capacity, but also opens up a strategy for accurate RA monitoring and synergistic amelioration.

Theoretical and experimental harmonic analysis of cracked blade vibration

Blade cracks pose deadly threats to aviation safety and have caused serious aviation accidents in recent years. In order to diagnose blade cracks at the early stage, the harmonic vibration of cracked blade was analyzed theoretically and experimentally. Firstly, a recursive form solution was deduced for the complex the nonlinear dynamic equation of blade vibration, revealing the close relationship between harmonic component power and crack parameters. Furthermore, the upper bound of the adjacent harmonic component power ratio was obtained by theoretical derivations. The results show that the harmonic power decreases as the harmonic component order increases, and the degree of attenuation is decided by the crack parameters. Therefore, a crack detection approach was proposed according to the power ratio of harmonic components. The advantage of this method is that the blades do not need to be in a resonant state and can process vibration data at all rotational frequencies. This improves data utilization and diagnostic robustness. The recommended method was validated by the simulation analysis of stainless-steel and titanium blades. Finally, a test bench for blade vibration was set up whose highlight was the use of optical sensors for non-contact measurements of blade vibration. The results of both simulation and testbed experiment were much consistent with the theoretical inference.

Gold Nanoclusters with Two Sets of Embedded Enzyme Nanoparticles for Applications as Electrochemical Sensors for Glucose

Enzyme-based electrochemical biosensors have been widely used because of their sensitivity, rapidity, and highly target-specific reactions. However, the immobilized enzymes can hinder electron transfer on the surface of the electrode and can decrease the sensitivity of electrochemical biosensors. To overcome this problem, we synthesized conductive gold nanoclusters with two sets of embedded enzyme nanoparticles, which are called gold nanocluster-embedded dual-enzyme nanoparticles (AuNC-DENPs) composed of a glucose oxidase-stabilized gold nanocluster (GOX-AuNC) and a horseradish peroxide-stabilized gold nanocluster (HRP-AuNC). Moreover, the application of these nanoparticles as an enzyme-based highly sensitive electrochemical sensor was investigated. Owing to the effect of AuNCs, these nanoparticles have good conductivity compared to bare protein nanoparticles. In addition, the synthesized AuNC-DENPs enabled the combination of a two-enzyme cascade reaction, in which the GOX-AuNC component of the nanoparticle oxidized glucose to generate hydrogen peroxide, which then reacted with the adjacent HRP-AuNC component on the nanoparticle. Given the proximity of the two enzyme components in a single nanoparticle, the AuNC-DENPs markedly reduced the diffusion and decomposition of H2O2 during the cascade reaction and showed an enhanced catalytic reaction compared to a mixture of enzymes. As a result, the biosensor exhibited high sensitivity (18,944 μA/mM cm2) and could detect very low concentrations of glucose ranging from 5 to 320 nM and a LOD of 2.58 nM. In addition, by analyzing nontarget materials and serum together with glucose, it was confirmed that the sensor has good selectivity for glucose.

A Comparative Analysis of Doherty and Outphasing MMIC GaN Power Amplifiers for 5G Applications.

A comparison between a fully integrated Doherty power amplifier (DPA) and outphasing power amplifier (OPA) for fifth Generation (5G) wireless communications is presented in this paper. Both amplifiers are integrated using pHEMT transistors from the OMMIC's 100 nm GaN-on-Si technology (D01GH). After a theoretical analysis, the design and layout of both circuits are presented. The DPA uses an asymmetric configuration where the main amplifier is biased in class AB and the auxiliary amplifier is biased in class C, while the OPA uses two amplifiers biased in class B. In the comparative analysis, it has been observed that the OPA presents a better performance in terms of maximum power added efficiency (PAE), while the DPA provides higher linearity and efficiency at 7.5 dB output back-off (OBO). At a 1 dB compression point, the OPA exhibits an output power of 33 dBm with a maximum PAE of 58.3% compared to 44.2% for the DPA for an output power of 35 dBm, and at 7.5 dB OBO, the DPA achieves a PAE of 38.5%, while the OPA achieves 26.1%. The area has been optimized using absorbing adjacent component techniques, resulting in an area of 3.26 mm2 for the DPA and 3.18 mm2 for the OPA.

Simulative and Experimental Investigation of the Ring Creeping Damage Mechanism Considering the Training Effect in Large-Sized Bearings

In this work, an advanced, numerical simulation method based on finite element analyses was developed in order to simultaneously take into account both roller- and structural-induced ring creeping phenomena. Ring creeping in general refers to a failure mode caused by a (non-bolted) bearing ring rotating relatively to its adjacent component such as, e.g., shaft or housing during operation. In particular, the coefficient of friction at the contact interface between bearing ring and adjacent component has a crucial influence. In order to consider this effect, a bearing ring creeping test rig based on component-like specimen was developed. Experimental results with respect to (i) measured creeping parameters such as creeping distance and (ii) the coefficient of friction due to run-in effects were described. Finally, experimental and numerical results were compared qualitatively to approve the reasonableness of the simulation model. The developed simulation approach enables the consideration of the entire drive train system within the micro-scale creeping evaluation procedure and therefore supports both drive train and bearing design-specific optimization measures in order to increase the reliability and robustness of a main bearing arrangement.

Correlations of PTEN and ERG Immunoexpression in Prostate Carcinoma and Lesions Related to Its Natural History: Clinical Perspectives.

Purpose: The aim of our study was to observe the associations between the ETS-related gene (ERG) and the phosphatase and tensin homolog gene (PTEN) immunoexpression in prostate cancer and related lesions and highlight the clinical significance of these findings. Methods: We evaluated the immunohistochemical expression of ERG and PTEN in a series of 151 invasive prostate adenocarcinomas, including low-grade (Gleason grade pattern 3) and high-grade (Gleason grade patterns 4, 5) morphological patterns which corresponded to 45.5% and 54.4% of the cases, respectively. Additionally, we evaluated the immunoexpression of the two markers both in foci of high-grade prostatic intraepithelial neoplasia (HGPIN), as a precursor lesion of cancer, and in foci of intraductal carcinoma of the prostate (IDCP). Finally, to ensure the malignant nature of the prostate glands examined, we employed p63 and alpha-methylacyl-CoA racemase (AMACR) expression. Results: We found that PTEN loss was observed in 50.7%, and ERG positivity was detected in 41.8% of our cancerous samples. In HGPIN, PTEN loss appeared to be linked with a high-grade adjacent invasive carcinoma component which also displayed PTEN loss. As far as IDCP is concerned, ERG immunonegativity was correlated with adjacent high-grade invasive cancer, which was also ERG immunonegative. Conclusions: Our findings suggest that the clonal expansion of invasive cancer appears to be associated with distinct immunophenotypic cellular alterations of both early and late cancer-related histological lesions. Patients with PTEN loss in HGPIN in prostate biopsies should be closely monitored due to the increased likelihood of having an associated invasive high-grade carcinoma that may have not been sampled. Given the clinical significance that derives from PTEN expression in HGPIN lesions, we suggest the routine use of PTEN immunohistochemistry in prostate cancer biopsies in which HGPIN is the only finding.

Abstract 10605: Percutaneous Debulking of Tricuspid Valve Endocarditis in Severe Covid-19 Pneumonia After Prolonged Advanced Life Support: A Case Series

Background: Over the past two years, the utilization of venovenous extracorporeal membrane oxygenation (VV-ECMO) for the treatment of coronavirus disease 2019 (Covid-19) acute respiratory distress syndrome (ARDS) has increased. While supporting respiratory function, VV-ECMO requires large-bore indwelling venous cannulas which risk bleeding and infections, including endocarditis. Case Summary: We describe the cases of a 48-year-old female and 39-year-old male patient hospitalized for Covid-19 pneumonia who developed ARDS and right ventricular failure, requiring VV-ECMO and Protek Duo cannulation. The female patient was decannulated from VV-ECMO after 123 days, but subsequently developed a segmental pulmonary embolism and tricuspid mass measuring 6.4 x 5.5 x 0.5 cm (fig A). After 116 days of VV-ECMO support, the male patient developed a tricuspid valve vegetation measuring 1.4 x 1.1 cm (fig B) with an adjacent right atrial component measuring 2.1 x 1.3 cm. The Inari FlowTriever system was used to percutaneously remove both the pulmonary embolism from the female patient and the tricuspid masses from both patients. Pathological examination of the mass from the female patient demonstrated Candida albicans endocarditis in the setting of Candida fungemia (fig C). Pathologic examination of the specimens from the male patient demonstrated endocarditis consistent with Pseudomonas aeruginosa in the setting of Pseudomonas bacteremia (fig D). Both patients experienced resolution of fungemia and bacteremia after percutaneous vegetation removal, and after prolonged hospital courses were discharged with supplemental oxygen. Discussion: VV-ECMO and right ventricular support devices are invasive and associated with bloodstream infection and infective endocarditis. Percutaneous debulking of valvular vegetations, associated with these right-sided indwelling catheters, may be an effective method of source control to prevent progression to valve surgery.

Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors

AbstractMullerian adenosarcoma is an uncommon mesenchymal tumor of the gynecologic tract. Most cases are low-grade, while high-grade adenosarcomas are rare and not well studied. Herein, we characterize the clinicopathologic and molecular features of 27 adenosarcomas of gynecologic origin, enriched for high-grade tumors subjected to targeted panel sequencing. Sarcomatous overgrowth was more frequently seen in high-grade compared to low-grade tumors (12/17, 71%, vs 1/10, 10%, p = 0.004) and heterologous elements were exclusive to high-grade cases (n = 7, p = 0.03). All deaths were from high-grade disease (advanced primary, n = 2, or recurrence, n = 5). Genetic alterations specific to high-grade adenosarcomas have known associations with chromosome instability, including TP53 mutations (n = 4) and amplifications of MDM2 (n = 2) and CCNE1 (n = 2). Somatic ATRX frameshift mutations were found in 2 patients with high-grade recurrences following a primary low-grade adenosarcoma and ATRX deletion in 1 high-grade adenosarcoma with an adjacent low-grade component. The fraction of genome altered by copy number alterations was significantly higher in high-grade compared to low-grade adenosarcomas (P = 0.001). Other recurrent genetic alterations across the entire cohort included BAP1 homozygous deletions (n = 4), DICER1 mutations (n = 4), ARID1A mutations (n = 3), TERT promoter mutations (n = 2) and amplification (n = 1), as well as alterations involving members of the PI3K and MAPK signaling pathways. One tumor harbored an ESR1-NCOA3 fusion and another had an MLH1 homozygous deletion. Immunohistochemical analysis for BAP1 revealed loss of nuclear expression in 6/24 (25%) cases, including all four tumors with BAP1 deletions. Notably, out of 196 mesenchymal neoplasms of gynecologic origin, BAP1 homozygous deletion was only found in adenosarcomas (P = 0.0003). This study demonstrates that high-grade adenosarcomas are heterogeneous at the molecular level and are characterized by genomic instability and TP53 mutations; ATRX loss may be involved in high-grade transformation of low-grade adenosarcoma; and BAP1 inactivation appears to be a specific pathogenic driver in a subset of adenosarcomas.

PSAT276 A Case of Malignant Struma Ovarii: Management After Surgery

Abstract Background Struma ovarii is a highly specialized and extremely rare monodermal ovarian teratoma that comprises 0.3 to 1% of all ovarian tumors. It consists of greater than 50% of mature thyroid tissue that is usually benign, but malignancy has been reported in up to 5- 23% of the cases. Even after surgery, recurrence rates of malignant struma ovarii can be as high as 35%. [1] Adjuvant thyroid targeting therapies such as radioiodine ablation after total thyroidectomy and TSH suppression therapy have been shown to reduce the risk of tumor recurrence similar to that of primary thyroid cancer. Case Description A 46-year-old healthy lady presented with a 3-month history of non-specific lower abdominal pain and inter-menstrual bleeding. An extensive review of systems was otherwise unremarkable. Ultrasound of the pelvis showed a 4 cm left adnexal mass. An MRI of the pelvis revealed a 2.2×3.6×2.4 cm solid, enhancing mass within the left ovary with an adjacent cystic component. Tumor markers including CEA, CA 19-9, and CA 125 were unremarkable. Due to suspicion for malignancy, she underwent laparoscopic left salpingo-oophorectomy and resection of the mass. Histopathology revealed papillary thyroid carcinoma approximately 1 cm in size with a background of struma ovarii. Immunohistochemistry staining showed positivity for thyroglobulin and Thyroid Transcription Factor-1 (TTF-1). BRAF mutation analysis was negative. An ultrasound of the thyroid gland disclosed two low-risk nodules. TSH was 1.070 mcIU/ml (0.450-4.500), and thyroglobulin level was 6.8ng/ml (1.5-38.5). We performed an Iodine-123 whole-body scan which was negative for abnormal radioiodine uptake. Based on these results, we classified this patients’ recurrence risk as low to intermediate. We initiated TSH suppression therapy with thyroid hormone to maintain TSH in the low normal range. We deferred total thyroidectomy and radioiodine ablation given the low recurrence risk. She will be monitored for recurrence with TSH and thyroglobulin panel at 6 and 12 months in the first year and then annually for at least the next ten years. Discussion Given the rarity of malignant struma ovarii, there are no consensus guidelines for identifying patients with a high recurrence risk who would benefit from thyroid targeting therapy. While some authors recommend total thyroidectomy and radioiodine ablation for all patients, a recent review [2] recommended an algorithm based on imaging, laboratory, and pathologic characteristics of the tumor to risk-stratify patients and treat them depending on their recurrence risk. Improved strategies for risk-stratification and follow-up are essential to provide optimal treatment for malignant struma ovarii patients without over-treating them.

THERMAL-INDUCED DAMAGE ON SOLDER JOINTS OF HIGH-DENSITY ADJACENT BALL GRID ARRAY COMPONENTS DURING THE REWORK PROCESS

Correlation between adjacent ball grid array (BGA) components' temperature and thermal-induced damage to their solder joints on both the top and bottom printed circuit board assembly (PCBA) sides during the rework process is studied in this work. Total often adjacent BGA components from the rework area on the top (F - K) and bottom (A - E) PCBA side were observed. The dye and pull (D&P) test results, infrared thermography images, and temperature measurements were analyzed for solder joint crack induced by the thermal damage with precise temperature measurement on each adjacent BGA component. Scanning electron microscope (SEM) analysis complemented the post-D&P test solder joint crack observation. The D&P test results shows that 76 % or higher and solder joint separation locations at the copper pad on BGA occurred when the temperature of the adjacent components of the rework location exceeded 195 °C and 210 °C on the centre and corner of the component, respectively.

Locally Adapted Microstructures in an Additively Manufactured Titanium Aluminide Alloy Through Process Parameter Variation and Heat Treatment

Electron beam powder bed fusion (PBF‐EB/M) has been attracting great research interest as a promising technology for additive manufacturing of titanium aluminide alloys. However, challenges often arise from the process‐induced evaporation of aluminum, which is linked to the PBF‐EB/M process parameters. This study applies different volumetric energy densities during PBF‐EB/M processing to deliberately adjust the aluminum contents in additively manufactured Ti–43.5Al–4Nb–1Mo–0.1B (TNM‐B1) samples. The specimens are subsequently subjected to hot isostatic pressing (HIP) and a two‐step heat treatment. The influence of process parameter variation and heat treatments on microstructure and defect distribution are investigated using optical and scanning electron microscopy, as well as X‐ray computed tomography (CT). Depending on the aluminum content, shifts in the phase transition temperatures can be identified via differential scanning calorimetry (DSC). It is confirmed that the microstructure after heat treatment is strongly linked to the PBF‐EB/M parameters and the associated aluminum evaporation. The feasibility of producing locally adapted microstructures within one component through process parameter variation and subsequent heat treatment can be demonstrated. Thus, fully lamellar and nearly lamellar microstructures in two adjacent component areas can be adjusted, respectively.

Effect of heat shield locations on rework-induced thermal management in ball grid array solder joint

This study investigated the effectiveness of heat shield placement locations during the rework process to avoid thermal and mechanical damage to adjacent ball grid array components and their solder joints on double-sided printed circuit board assembly. Three types of heat shield placement locations were used: sample X, individual heat shield placement on adjacent components of the rework location; sample Y, a U-shaped, and sample Z, a square-shaped heat shield placed respectively at the heat source location. The dye and pull test results, infrared thermography, and temperature measurements were analysed to understand the relationship between the location of the heat shield and solder joint damage during rework. Heat shield placement at the heat source location on the reworked component can reduce the peak temperatures on the adjacent rework component locations by up to 8.18%. The peak temperatures of the centre and corner of the BGA component can be maintained below 195 °C and 210 °C, respectively to improve the adjacent rework component locations' solder joint quality by reducing solder joint damage by more than 50% solder cracks. This is useful for thermal management during rework involving high-density ball grid array component placements on double-sided printed circuit board assembly.

Universal dimension reduced phase compensation algorithm for an optical phased array.

Optical phased arrays (OPAs) can achieve non-mechanical beam deflection. Many types of OPA face the problem of low deflection efficiency due to the phase distortion induced by mutual coupling between nearby channels. In this Letter, a universal optimization algorithm is proposed to compensate for this structural phase distortion, in which the adjacent sampling principal component analysis (AS-PCA) method is introduced to reduce the dimension of the solution space. Simulations and experimental results on different classes of OPA verified that this method can considerably optimize the deflection beam with a rapid convergence speed, irrespective of the scale of OPA, and maintain the universal feature, laying the foundation for large-scale, high-density OPA in-line optimization. We envision it to become a general method on different platforms.

Completely foldable electronics based on homojunction polymer transistors and logics.

An increase in the demand for completely foldable electronics has motivated efforts for the development of conducting polymer electrodes having extraordinary mechanical stability. However, weak physical adhesion at intrinsic heterojunctions has been a challenge in foldable electronics. This paper reports the completely foldable polymer thin-film transistors (PTFTs) and logic gate arrays. Homojunction-based PTFTs were fabricated by selectively doping p-type diketopyrrolopyrrole-based semiconducting polymer films with FeCl3 to form source/drain electrodes. The doping process caused a gradual work function change with depth, which promoted charge injection to semiconducting regions and provided a low contact resistance. In addition, the interfacial adhesion in the PTFTs was improved by interfacial cross-linking between adjacent component layers. The electrical performance of the resulting PTFTs was maintained without noticeable degradation even after extreme folding, suggesting that the proposed fabrication strategy can further be applied to various semiconducting polymers for the realization of foldable electronics.

Noise Suppression for Ultrasound Attenuation Coefficient Estimation Based on Spectrum Normalization.

Ultrasound attenuation coefficient estimation (ACE) has great diagnostic potential for fatty liver detection and assessment. In a previous study, we proposed a reference phantom-free ACE method, called reference frequency method (RFM), which does not require a calibrated phantom for normalization. The power of each frequency component can be normalized by the power of an adjacent frequency component in the spectrum to cancel system-dependent effects such as focusing and time gain compensation (TGC). RFM demonstrated accurate ACE in both phantom and in in-vivo liver studies. However, our study also showed that the robustness and penetration of RFM were affected by noise in the ACE signals. Here we propose a noise suppression (NS) and a signal-to-noise ratio (SNR) quality control method to reduce the influence of noise on ACE-RFM performance. The proposed methods were tested in harmonic ACE because harmonic imaging is a more frequently used mode than fundamental imaging for abdominal applications. After applying the NS and SNR control methods, the noise-induced bias for attenuation estimation in harmonic ACE was effectively reduced, leading to significantly improved effective penetration depth. The proposed methods directly measure the noise spectrum of the ultrasound system, which can also be adapted to other spectrum-based ACE methods, such as the reference phantom method and the spectra shift method.

Lattice Boltzmann simulation of phase change and heat transfer characteristics in the multi-layer deposition

The metal droplets deposition method (MDDM) is a rapid prototyping technology, implemented via metallurgy bonding within droplets. The anisotropy of heat transfer and re-melting is caused by an asymmetric deposition process. A lattice Boltzmann method (LBM) model is established to predict the heat transfer and phase change in the multi-layer deposition. The prediction model is verified by the experimental temperature profiles in existing literature. The monitoring points are set to compare the temperature profiles, and decoupling analyze the heat transfer mechanism in different positions. The negative relationships between the re-molten volume of the temperature difference, as well as the influence of the dispositive position and the relative position of the adjacent component are observed and analyzed under the heat conduction. This work is helpful to choose the appropriate temperature conditions and the optimal dispositive method.

Optical and Electronic Losses Arising from Physically Mixed Interfacial Layers in Perovskite Solar Cells.

Perovskite solar cell device performance is affected by optical and electronic losses. To minimize these losses in solar cells, it is important to identify their sources. Here, we report the optical and electronic losses arising from physically mixed interfacial layers between the adjacent component materials in highly efficient two terminal (2T) all-perovskite tandem, single-junction wide-bandgap, and single-junction narrow-bandgap perovskite-based solar cells. Physically mixed interfacial layers as the sources of optical and electronic losses are identified from spectroscopic ellipsometry measurements and data analysis followed by comparisons of simulated and measured external quantum efficiency spectra. Parasitic absorbance in the physically mixed regions between silver metal electrical contacts and electron transport layers (ETLs) near the back contact and a physical mixture of commercial indium tin oxide and hole transport layers (HTL) near the front electrical contact lead to substantial optical loss. A lower-density void + perovskite nucleation layer formed during perovskite deposition at the interface between the perovskite absorber layer and the HTL causes electronic losses because of incomplete collection of photogenerated carriers likely originating from poor coverage and passivation of the initially nucleating grains.

Sarcomatous Transformation of Unicentric Calcaneal Epithelioid Hemangioendothelioma: A Case Report with Review of Literature

Vascular origin tumors of bone are rare entities. Epithelioid hemangioendothelioma (EHE) is a rare tumor representing <1% of primary bone tumors and is considered a low to intermediate grade malignancy. Literature describes cases which were either a part of multicentric disease or were metastatic. In this study, we reported a case of a 23-year-old female with biopsy-proven EHE with prior history of resection, presenting with recurrence of disease. Radiographs showed a lytic lesion involving the left calceneum and other tarsal bones with extensive soft-tissue component. Magnetic resonance imaging revealed an ill-defined, enhancing, lobular, and lytic lesion with adjacent soft-tissues component. Computed tomography confirmed extensive destruction of the involved tarsal bones. EHE is treated with wide surgical excision and recurrence is rare; however, our case presented with recurrence as well as thoracic metastasis which posed a great clinical challenge. The patient was treated with below knee amputation and was given subsequent radiotherapy. The main aim of this study is to revisit the clinicopathological aspects as well as the spectral behavior of vascular bone tumors.

Accurate FE Computation for Out-of-plane Welding Distortion Prediction of Fillet Welding with Considering Self-Constraint

Inherent deformation as key parameter plays an essential role in elastic finite element (FE) analysis for welding distortion prediction. In this study, the self-constraints supported by surrounding base material and lateral stiffener were presented, where their influences on magnitudes of inherent deformation components were qualitatively examined. In detail, self-constraint supported by the surrounding base material will distinguish the inherent deformation as an individual physical representation; and self-constraint supported by the lateral stiffener will significantly influence the bending component and final deformed mode. Taking into account fillet welding and orthogonal stiffened welded structure as the application, experiments were conducted for out-of-plane welding distortion measurement. Transient nonlinear thermal elastic-plastic FE analysis of fillet welding was carried out to evaluate inherent deformation after validation with the measured data; then, elastic FE analysis with inherent deformation was carried out to accurately predict the out-of-plane welding distortion and welding buckling behavior in fabrication of an orthogonal stiffened welded structure which is a part of typical ship panel, and there is a good agreement between the predicted and measured welding distortion. 1. Introduction Up to now, fusion welding which is considered as a main joining method because of its practical and high productive features is almost employed for component assembly in fabrication of marine structures, automobiles, trains, aircraft, bridges, pressure vessels, and others. However, during the fast heating and cooling processes, a narrow region near the welding line will expand and subsequently shrink because of the constraint of the surrounding base material, and then plastic strains are generated which are the primary cause of welding distortion and residual stress. Therefore, welding-induced distortion is inevitably generated during the welding process, and it will result in loss of dimensional control and structural integrity, trouble of subsequent alignment with the adjacent component, and increment of fabrication cost with straightening such as flame heating (Wang et al. 2015).