Adhesive Fixation Research Articles

Evaluation of clinical effectiveness of hygiene products for the care of facial prostheses

BACKGROUND: Because of the porous structure of the structural material used in the production of facial prostheses, without careful hygienic care, microbial biofilms may form on the material surface, its color and shape may change, and premature aging may occur. Means for the hygienic care of facial prostheses and research to confirm their clinical effectiveness are crucial in dentistry.
 AIM: To increase the effectiveness of the hygienic treatment of facial epitheses.
 METHODS: A single-center randomized study was conducted to assess the clinical effectiveness of hygiene products for the care of facial prostheses. This study involved patients with exenteration of the eye socket, previously prosthetic with adhesive fixation epitheses. The patients were divided into four groups and received different hygienic care methods. Furthermore, during the use of the prosthesis for 14 days and 1 and 3 months, the tissues of the prosthetic bed and hygienic condition of the prosthesis were evaluated, and the quality of life of patients was determined.
 RESULTS: According to the results of measuring the area of inflammation of tissues of the prosthetic bed of the eye socket at different terms, positive dynamics were found in the groups that used the proposed hygiene products.
 CONCLUSION: A strong positive correlation (r 0.9) of the average values of the quality of life index, area of inflammation, and hygiene index of the orbital epitheses in the study groups at the appropriate time indicates improved quality of life of patients who used the proposed hygiene products by reducing the amount of bacterial plaque on the surface of the epithesis and, in turn, reducing the area of inflammatory reactions and increasing comfort in wearing the prosthesis.

A 3D printed biomimetic scaffold for cartilage regeneration with lubrication, load-bearing, and adhesive fixation properties

Reconstructing the tri-layer structure of articular cartilage (AC) and replicating its functions pose significant challenges. In response, we propose a novel approach utilizing 3D printing technology to replicate and reconstruct the complex structure of AC. This is achieved by introducing three distinct functional hydrogels, each providing lubrication, load-bearing, and adhesive fixation functions. We have systematically characterized the structure, chemical composition, and function of each layer. The results demonstrate the effectiveness of the tri-layer scaffold, which exhibits low friction, mechanical properties similar to natural AC, excellent adhesion capacity, and good biocompatibility. This study paves the way for innovation in the traditional methods of preparing biomimetic AC and has broad applications in osteochondral (OC) defect repair.

Preservando esmalte: remoção segura de resíduos de resina após descolagem de bráquetes ortodônticos

ABSTRACT In conventional orthodontics, the adhesive fixation of brackets plays an essential role in the success of the treatment. However, the removal of these devices at the end of the treatment can pose risks of excessive wear to the external surface of the enamel, especially when rotary instruments are indiscriminately used to remove the resin composite employed in cementation. Given that enamel is an inorganic tissue with no regenerative capacity, it becomes imperative to adopt conservative techniques to minimize unnecessary wear. This text aimed to discuss more conservative approaches, exploring the use of multilayered burs instead of diamond tips, and associating them with polishing rubbers, magnification, and consideration of the fluorescence characteristics of adhesive materials. These practices are intended to minimize impact and preserve the integrity of the enamel. Reflecting on the indiscriminate use of diamond tips for enamel polishing emerges as essential in modern dental practice.

Canine ex vivo tarsal arthrodesis: fixation by using a new bone tissue glue.

Arthrodesis, performed as a salvage surgical procedure to treat intractable joint conditions in dogs and cats, is associated with a high incidence of complications intra and postoperative, proving the need for improved and new techniques in arthrodesis surgery. Adding a new resorbable bone glue to the arthrodesis could potentially add fixation strength and lower complications. The objectives of this experimental ex vivo biomechanical study were therefore to develop a biomechanical test model of partial tarsal arthrodesis and to determine whether the new resorbable bone glue (phosphoserine modified cement) produced measurable fixation strength in canine calcaneoquartal arthrodesis, without orthopedic implants. Four biomechanical test models with a total of 35 canine tarsal joints were used. Soft tissues were dissected to 4 different test models with variable contributions from soft tissues. The calcaneoquartal joint was prepared as in vivo arthrodesis and the glue was applied to joint surfaces as a liquid/putty (0.4 cc). After curing for 24 h, a shear force was applied to the joint (1 mm per minute) and the failure strength was recorded. Calcaneoquartal joints, where all soft tissues had been completely resected and fixated with glue (1-1.5 cm2 joint surface), withstood 2-5 mm of displacement and an average of 100 ± 58 N/cm2 of shear force (Model 1). Similar adhesive fixation strengths were obtained in Model 2 and 3 with increasing contributions from soft tissues (80 ± 44 and 63 ± 23 N/cm2, p = 0.39, ANOVA). The developed biomechanical model was sensitive enough to measure differences in fixation strengths between different glue formulations. The average fixation strength (60-100 N/cm2) should be strong enough to support short-term load bearing in medium sized canines (20 kg). The developed cadaver biomechanical test model is of potential use for other arthrodesis studies. The new resorbable glue can potentially contribute to stability at arthrodesis surgery, acting as a complement to today's standard fixation, metal implants.

Characteristics and applications of synthetic exogenous materials used in surgery for reconstruction of the orbital cavity

This study aims to provide the main features, indications, and contraindications of synthetic exogenous materials used to reconstruct defects in the orbital cavity. In addition, present the available clinical data on these biomaterials. This integrative literature review was carried out in the PubMed, Periódicos CAPES, and Virtual Health Library (VHL) databases in May and June 2022. At first, the search followed the following strategy on the PubMed and CAPES Periodicals platforms - (reconstructive surgical procedures AND orbit AND biomaterials). Then, in the VHL platform, with the combination - (orbit AND biomaterials). There were restrictions for articles published in the last five years. Titanium was the most frequently found material in this search, with 38% of the total number of articles. The material was also associated with Porous Polyethylene, Polyetheretherketone, and in the form of Titanium-Nickel alloy. The following materials were also included: Hydroxyapatite; Non-sintered hydroxyapatite particles and a composite sheet of Poly L'Lactide with adhesion fixation; Porous Polyethylene; Polytetrafluoroethylene; Polyetheretheretherketone; Polydioxanone; Polymethylmethacrylate; and Polycaprolactone. Orbital reconstruction surgeries can be challenging because of the anatomical complexity of the region and the impact that repairing this structure has on the individual. The most common alloplastic materials used for orbit reconstruction are titanium mesh and porous polyethylene. The type of injury, the particularities of each patient, the operator's training, the material's availability, and the technological apparatus should be considered in the clinical decision of which to use. Good results in orbital reconstruction surgeries require more and more innovations in technologies, materials, and professional training.

Triple-functional bone adhesive with enhanced internal fixation, bacteriostasis and osteoinductive properties for open fracture repair.

At present, effective fixation and anti-infection implant materials represent the mainstay for the treatment of open fractures. However, external fixation can cause nail tract infections and is ineffective for fixing small fracture fragments. Moreover, closed reduction and internal fixation during the early stage of injury can lead to potential bone infection, conducive to bone nonunion and delayed healing. Herein, we designed a bone adhesive with anti-infection, osteogenic and bone adhesion fixation properties to promote reduction and fixation of open fractures and subsequent soft tissue repair. It was prepared by the reaction of gelatin (Gel) and oxidized starch (OS) with vancomycin (VAN)-loaded mesoporous bioactive glass nanoparticles (MBGNs) covalently cross-linked with Schiff bases. Characterization and adhesion experiments were conducted to validate the successful preparation of the Gel-OS/VAN@MBGNs (GOVM-gel) adhesive. Meanwhile, in vitro cell experiments demonstrated its good antibacterial effects with the ability to stimulate bone marrow mesenchymal stem cell (BMSCs) proliferation, upregulate the expression of alkaline phosphatase (ALP) and osteogenic proteins (RunX2 and OPN) and enhance the deposition of calcium nodules. Additionally, we established a rat skull fracture model and a subcutaneous infection model. The histological analysis showed that bone adhesive enhanced osteogenesis, and in vivo experiments demonstrated that the number of inflammatory cells and bacteria was significantly reduced. Overall, the adhesive could promote early reduction of fractures and antibacterial and osteogenic effects, providing the foothold for treatment of this patient population.

Comparative assessment of the effectiveness of rehabilitation of patients with tissue defects of the maxillofacial area when using epitheses on magnetic and adhesive fixation

Comparative assessment of the effectiveness of rehabilitation of patients with tissue defects of the maxillofacial area when using epitheses on magnetic and adhesive fixation

Comparative study of microbial colonization of catheters for prolonged regional anesthesia when using different fixation methods

BACKGROUND: Infectious complications related to prolonged epidural and peripheral regional anesthesia are quite rare. However, this does not exclude the necessity of strict adherence to measures aimed at preventing microbial colonization of catheters for regional anesthesia. Microbial colonization of the catheter is not always accompanied by the development of infectious complications but increases the likelihood of their occurrence.
 AIM: To determine the frequency of colonization, the qualitative and quantitative composition of the microflora depending on the various methods of fixing of the catheter and the duration of its use.
 MATERIALS AND METHODS: 76 patients from 2 to 18 years old with prolonged epidural or peripheral anesthesia were included in an comparative, prospective, randomized, single-center study. Patients were divided into the groups according to the method of catheter fixation - adhesive sticker (AS), adhesive sticker and antimicrobial coating Desitol B (AS+D) and tunneling (T). Determination of microbial contamination of catheters was carried out using classical bacteriological studies.
 RESULTS: None of the 76 patients had signs of a local or systemic infection. The difference in the frequency of colonization between the AS and T groups was statistically significant: 2 (1, n = 54) = 5.5381 (p = 0.018), between the AS and AS+D groups it was not significant. The relative risk of colonization of the skin of the catheter with adhesive fixation was 2.14 times higher than with catheter tunneling: RR = 2.14, p = 0.05 (95% CI 1.04.49). In the AS+D group, colonization of both the skin and the inner part of the catheter was observed significantly earlier than in the T group: skin part: U = 5.5; Ucr = 8 (p = 0.02); inner part: U = 5.5; Ucr = 6 (p = 0.04). The growth of Staphylococcus epidermidis (48.3%) and Staphylococcus aureus (20.7%) was fixed mainly when positive results of microbiological culture takes place.
 CONCLUSIONS: Tunneling is the preferred method of fixation of the catheter when the postoperative pain relief period is more than 3 days.

RESEARCH OF TRANSVERSE GLUING OG LIGTHINDASTRY PARTS WITH POLIMERIC MATERIALS

The paper presents the results of research on the preliminary gluing of parts of light industry, namely parts made of leather and artificial leather into a package. Zonal application of polymer adhesive material and a defined strength value for different types of packages are proposed. The relative displacement of the parts will lead to a violation of the integrity of the package and the destruction of the adhesive bond between them. That is, any relative displacement of the parts must lead to the destruction of their previously set position and is considered unacceptable. Therefore, determining the strength of the adhesive fixation of parts, which keeps them in a given position and determines the main task of the research. The substance used as an adhesive must ensure the fixation of the details of the shoe upper in a short period of time. This time is necessary only for the formation and stitching of a package of parts and depends on the parameters of the technological process and the performance of the equipment. In our case, when a pair of shoe upper blanks must be formed in one minute. To accurately determine the strength of the adhesive interaction between two parts, it is proposed to use the method of shifting (tearing) the adhesive joint. It was taken into account that natural and artificial leather have front and back sides that differ from each other. Namely, the dorsal side has larger capillary radii and greater porosity than the front side. Polymer material for gluing – Desmocol – was also chosen for research. The obtained values made it possible to form a general characteristic of the strength of adhesive joints for this type of polymer material used as glue. The obtained data show that it is quite possible to use the proposed zonal application of polymer adhesive material to ensure the non-slip strength of pre-glued parts. The strength value is sufficient for the further transportation of parts of the light industry to the next technological position without displacement. This can be used for systems of automated assembly of shoe upper blanks, stitching, manipulation, etc.

Результаты хирургического лечения птеригиума с применением двухкомпонентного аутофибринового клея

The only effective way to treat pterygium is to perform surgical intervention in various ways (without replacing the defect of the conjunctiva and replacing the defect with allogeneic or autologous tissues). One of the most effective methods is considered to be the removal of the pterygium with defect plasty with an amniotic membrane. The issue of choosing the fixation of the amniotic membrane is topical. The use of a suture fixation method is considered the gold standard, but this method increases the duration of the operation, and is also accompanied by discomfort for the patient in the postoperative period. The use of an adhesive fixation method using autologous fibrin adhesives is considered promising. Purpose of the study: to conduct a comparative analysis of the effectiveness of surgical treatment of pterygium using a two-component autofibrin glue and sutures for fixing the amniotic membrane. Material and methods. The study included 15 patients. All patients were divided into 2 groups depending on the method of fixing the amniotic membrane: the 1st group was the main group, where the amniotic membrane was fixed with a two-component autofibrin glue, the 2nd group was the control group, where the amniotic membrane was fixed with sutures. All patients underwent biomicroscopy and optical coherence tomography of the anterior segment to determine the stage of pterygium. Before surgical treatment, tear production was assessed using the Schirmer test. The study groups compared the time spent on the operation. After the surgical intervention, the control periods were followed by photo registration, optical coherence tomography of the anterior segment, as well as an assessment of the presence of the following "symptoms" in the patient: pain, sensation of a foreign body, itching, lacrimation, assessed in points on a visual analogue scale. After 6 months, the presence of pterygium recurrence in the study groups was assessed. Statistical analysis was carried out using the StatTech v. 2.8.8. Results. As a result of evaluating the indicator "Duration of surgery" depending on the study group, we found statistically significant differences (p = 0.032). When assessing the "Pain" indicator, statistically significant differences were detected on the 1st (p = 0.007), 3rd (p = 0.03) and 7th days (p = 0.047) after the operation. When assessing the indicators of the presence of "Foreign body sensation" and "Itching", statistically significant differences between the groups were detected only on the 1st day after the operation (p = 0.04 and p = 0.017, respectively), in the remaining control periods, differences between the groups were revealed did not have. When analyzing the indicator of "Lacrimation", no statistically significant differences between the studied groups were revealed for all control periods of the study. No recurrence of pterygium was recorded in any of the cases 6 months after the surgical interventions. Conclusion. Fixation of the amniotic membrane with the help of the developed two-component autofibrin glue during the surgical treatment of pterygium provides not only a reduction in the operation time, but also a more comfortable postoperative period. Keywords: pterygium, autofibrin glue, surgical treatment, amniotic membrane.

Nurses' knowledge and experiences of peripheral intravenous catheter insertion at a tertiary paediatric health centre.

The aim of the study was to determine paediatric nurses' knowledge and experiences of PIVC insertion. In this cross-sectional study, nurses working in a paediatric hospital in Izmir, Türkiye, between May and September 2019 were included (225; 67.4%). A PIVC knowledge and experience form, and a sociodemographic characteristics questionnaire were used to collect data. Nurses most often inserted the PIVC on the dorsum of the hand (83.1%). Their choice of vein was influenced by the condition of the patient's veins (91.1%), medications (72%) and the patient's activity status (70.2%). The most preferred PIVC size was 24 gauge (98.2%), and the most frequently used cannula was a short peripheral cannula (96.9%). To clean the insertion site of the cannula, 93.8% of the nurses used 70% alcohol. Distractions used while inserting the PIVC were: letting the child play with a toy (51.1%), having the child sit on the mother's lap (45.8%), letting the child watch cartoons (45.3%), and administering oral sucrose (43.6%). Of the nurses, 69.3% attached a split septum/vein valve to the PIVC insertion site, and 82.2% cleaned the split septum/vein valve with 70% alcohol and waited until it dried before administering the medication. Some 79.6% secured the cannula with a hypoallergenic nonwoven adhesive fixation tape bandage. Some 94.7% performed catheter flushing for control after inserting PIVCs, 93.8% performed catheter flushing before IV fluid treatment, 89.8% flushed the catheter before drug administration through the bolus method, 53.3% flushed the PIVC catheter with a slow technique and 42.2% flushed it with an intermittent technique. The nurses generally acted in accordance with Infusion Nurses Society (2016) guidance. It would be helpful if the hospital developed algorithms that include standards to prevent and manage PIVC insertions and complications.

Changes of Age-related Auricular Cartilage Plasticity and Biomechanical Property in a Rabbit Model.

Ear molding is an emerging technique that can correct auricular deformities. Treatment initiation time is the most important prognostic determinant of ear molding. Here, we aimed to examine why auricular cartilage plasticity appeared to diminish with age. Thus, we characterized age-related changes in the biomechanical, biochemical, and morphological properties of auricular cartilage. New Zealand rabbits were used as the experimental animal. We examined immature [postnatal 0 day (P0), 5 days (P5), 15 days (P15)], young [2 months (2M)], and mature [6 months (6M)] rabbits. Rabbits' ears were splinted and folded using adhesive fixation strips. Folding duration ranged from 1 day to 5 days to 10 days. Photographs were taken to calculate the retained fold angle. Cartilage morphology and extracellular matrix (ECM) content were examined histologically (using hematoxylin-eosin, Safranin O, elastic Van Gieson, and Masson's trichrome). Water content, DNA content, and cell density were also analyzed. Biomechanical properties were measured using a Nano indenter. Immature ears had smaller angles after strip removal, and the angled deformation lasted a longer time. Cartilage matrix compositions, including glycosaminoglycan (GAG), elastin fiber, and collagen, increased over development. The water content, DNA content, and cell density decreased with age. Young's modulus was significantly higher in mature cartilage. Here, we successfully established an animal model of ear molding and demonstrated that immature cartilage was associated with better plasticity. We also found that the cartilage's biomechanical property increased with the accumulation of ECM. The biomechanical change could underlie age-related shape plasticity. NA Laryngoscope, 133:88-94, 2023.

Adhesion of dental cements to zirconia restorations. Part 2

The information about methods of surface preparation for dentures made from ceramic based on zirconium dioxide for better adhesive fixation is presented in the first part of this article. Micromechanical methods of preparation for cementation of the surface of a zirconia dental prosthesis are discussed in the first part of this article. The second part of the article provides an overview of scientific research on chemical methods for preparing a surface made of zirconia and the problem of the bond strength of polymer cement with a prepared surface made of zirconia.

Adhesion of dental cements to zirconia restorations (part 1)

The analysis of modern scientific data on traditional and adhesive fixation of zirconia restorations, adhesion of various cements to zirconium dioxide, methods of surface preparation of ceramic restorations is presented. Micromechanical methods of preparation for cementation of the surface of a zirconia dental prosthesis are discussed in Part 1.

Comparative assessment of composites landing adaptation for dental restoration in experiments

Background. In modern dental practice, there is a problem of complications after treatment of caries, such as the postoperative sensitivity of the tooth, formation of secondary caries, and caries complications in the form of pulpitis or periodontitis of the tooth. In addition, this problem exists despite the achievements in the production of high-quality composite filling materials, which are very popular among dentists worldwide. One of the problems that lead to complications after caries treatment is a violation of the integrity of the adhesive bond between the composite and the tooth tissue, which is manifested by a violation of the seal of restoration and the formation of a gap between the filling material and the tooth tissues. This in turn leads to the development of tooth sensitivity and the possibility of bacterial invasion between the filling material and the walls of the tooth, followed by the progression of the pathological process. In the scientific literature, there is evidence of the positive effect of preheating and vibration on the composite before its polymerization.
 Aim. Additionally, the purpose of this study is to determine the effect of physical impact, such as heating and vibration, on the composite using ultrasound in order to improve the quality of the adhesive fixation of the composite filling material to the walls of the tooth.
 Materials and methods. The study was conducted on the extracted teeth of patients. Based on this, we have proposed a method for the simultaneous thermo-vibration action on a non-polymerized composite directly in the formed tooth cavity to improve the physicochemical, including the adhesive, properties of light-curing composites.
 Results of the study revealed a statistically significant positive effect of thermo-vibration on the composite, not only in comparison with the classical method of working with the composite at room temperature, but also with the method of preheating the composite in a furnace used for heating the composite.

АДГЕЗИВНЫЕ СИСТЕМЫ В ПРАКТИКЕ ВРАЧА-СТОМАТОЛОГА

Subject. Dental restoration includes work on tissue restoration by filling, using inlays, veneers, and artificial crowns.
 Adhesive systems are used in therapeutic dentistry for working with composites, compomers and some glass-ionomer cements, for adhesive fixation of all types of indirect structures, repairing chips of composite and ceramic linings; in pediatric dentistry for sealing fissures, for fixing orthodontic structures. Currently, there are eight generations of adhesives on the market of dental materials. The first two generations of adhesives required only enamel etching and transformed the dentin layer, while the third already provided for conditioning of the dentin, and the fourth and fifth ― and all-out etching. The sixth, seventh and eighth generations of adhesives are self-etching analogues. This article presents the results of a survey of practical health care dentists in choosing an adhesive system.
 The goal is to evaluate the preferences of the choice of adhesive systems by dentists.
 Methodology. 30 dental therapists and orthopedic dentists took part in the survey.
 Results. The results of the questionnaire analysis showed that the majority of dentists prefer to use fifth-generation adhesives in their practice (46 %), the sixth generation of adhesive systems is in second place in popularity (31 %), followed by the "gold standard" ― the fourth generation (13 %), and the seventh (10 %) in last place.
 Conclusions. The fifth-generation adhesive systems surpassed the other generations in efficiency and reliability. This is why the majority of dentists surveyed chose this generation.

Surgical treatment for type II macular hole retinal detachment in pathologic myopia.

To observe the effectiveness and complications of inverted internal limiting membrane insertion through 25-G minimally invasive vitrectomy assisted with autologous blood adhesion fixation and combined with gas tamponade type-II macular hole retinal detachment in pathologic myopia.This was a retrospective study. The best-corrected visual acuity, intraocular pressure, macular hole closure, retinal reattachment, and systemic and ocular adverse events were observed.Twenty-three eyes were operated. Best-corrected visual acuity before surgery and at 3 and 6 months were 2.25 ± 0.47, 1.85 ± 0.32, and 1.32 ± 0.36 LogMAR (P < .001). On days 2 to 5, all the retinas reattached, and the macular holes closed. On days 5 to 9, 5 eyes showed increased intraocular pressure. At 2 and 4 months, 2 eyes showed retinal detachment recurrence. No serious systemic or ocular adverse events were observed.This surgical technique showed clinical benefits and no significant complications. Clinical trials are necessary to confirm efficacy and safety.

Efficacy of Autologous Serum in Fixing Conjunctival Autografts of Various Sizes in Different Types and Grades of Pterygium.

Purpose:To evaluate the efficacy of autologous serum in fixing conjunctival autografts of various sizes in different grades and types of pterygium and to determine the largest successfully secured graft size.Methods:This prospective interventional study comprised 151 eyes of 151 patients belonging to age group of 21 to 64 years with different grades and types of primary and recurrent pterygium that underwent excision with inferior conjunctivo - limbal autograft secured with autologous serum. The autografts were measured with calipers and were grouped by size into three categories: Group A, small (5 × 5 mm); Group B, medium (5–7 × 5 mm); and Group C, large (>7 × 5 mm). The adhesive fixation power of autologous serum for the various conjunctival autograft sizes was determined for each group using the following criteria: graft stability, cosmetic appearance and complications in the immediate ( first week) and two-months postoperative follow-up visits. Descriptive statistical analysis was used to calculate the percentage frequency of the variables.Results:The groups A, B, and C included 48%, 22%, and 30% of the autografts, respectively. Overall, 93.34% of the grafts were stable with good cosmetic appearance. However, subconjunctival hemorrhage (36%), graft edema (36%) and graft retraction (13.5%) were the most common complications. The largest successfully fixed graft was 14 × 5 mm in size.Conclusion:Autologous serum is efficient in securing conjunctival autografts of various sizes with minimal complications and satisfactory results, including good cosmesis.

Effect of sandblasting on the microroughness of ceramic restorations

The influence of aero-abrasive technology on the microroughness of the ceramic samples standardized in shape, structure, and manufacturing method was studied by comparing the results obtained from the action of alumina particles of 27 and 50 μm size under a pressure of 0.5 and 2 atm for 5 seconds at a distance of 3 cm. To objectify the features of the treated surface relief its micro-roughness has been studied. With the help of a scanning electron microscope the morphology of studied samples was visualized. The data confirming the reliable absence of differences in the microroughness between the sandblasting methods under the given conditions was obtained. Microphotographs of samples surface obtained using the mode of reflected electrons detection showed no significant structural differences between all groups of samples. Thus, sandblasting can be integrated into the general algorithm as a stage of ceramics preparation for adhesive fixation since it does not cause mechanical damage to the surface, does not fundamentally change its structure and cleans the surface from contamination.

Comparative study on fixation of central venous catheter by suture versus adhesive device

ObjectivesTo assess the efficacy of a central venous catheter adhesive fixation device (CVC) to prevent associated complications. To establish the need for dressing changes, number of days’ catheterization and reasons for catheter removal in both study groups. To assess the degree of satisfaction of personnel with the adhesive system. MethodA, randomised, prospective and open pilot study, of parallel groups, with comparative evaluation between CVC fixation with suture and with an adhesive safety system. The study was performed in the Coronary Unit of the Universitari de Bellvitge Hospital, between April and November 2016. The population studied were patients with a CVC. The results were analysed using SPSS Statistics software. The study was approved by the Clinical Research Ethics Committee. Results100 patients (47 adhesive system and 53 suture) were analysed. Both groups were homogeneous in terms of demographic variables, anticoagulation and days of catheterization. The frequency of complications in the adhesive system group was 21.3%, while in the suture group it was 47.2% (p=.01). The suture group had a higher frequency of local signs of infection (p=.006), catheter displacement (p=.005), and catheter-associated bacteraemia (p=.05). The use of adhesive fixation was associated with a lower requirement for dressing changes due to bleeding (p=.006). Ninety-six point seven percent of the staff recommended using the adhesive safety system. ConclusionsThe catheters fixed with adhesive systems had fewer infectious complications and less displacement.