Adequate Retention Research Articles

A novel Approach to Maxillary Long Kennedy Class II RPD Crossing Midline

Statement of problem: Unilateral distal-extension removable partial dentures (RPD) have always posed a challenging situation to the clinician particularly when it crossed the midline and having a linear alignment of the abutments. In such cases, providing adequate retention and stability is problematic thus, the good selection of the direct and indirect retainers would ensure the long-term success of the prosthesis and the remaining abutments. Purpose: The aim of this study was to apply the idea of unilateral obturator Aramany class IV principles to the patients suffering from linearly aligned abutments long Kennedy class II RPD crossing the midline through using buccal retention and lingual retention with guiding plane composite build-ups clasp designs. Treatment Plan: Three patients were treated in this study. All the patients are fully dentate or with restored mandibular jaw and partially edentulous maxillary jaw (Kennedy class II) crossing the midline with a maximum of six teeth present in a linear alignment. Each patient received RPD that was retained through engaging the buccal undercut on anterior distal abutment and lingual undercut with composite build-up guiding plane on posterior distal abutment. Conclusions: Our findings suggest that buccal retention on anterior abutments and lingual retention and guiding planes on posterior abutments for linear class II maxillary RPD provided better patient satisfaction and more retentive capability than RPD with regular buccal retention design.

A Metasurface Glass for Energy Saving and 5G Mobile Communication Signal Enhancement.

Windows constitute a significant portion of the facade in buildings and modern ground transportation vehicles, such as commercial skyscrapers, high-speed trains, and subway systems. Traditional glass windows lack adequate thermal insulation and heat retention capabilities; Low-Emissivity (Low-E) glass can block external infrared radiation, it also impedes mobile communication signals, particularly those in the 5G Sub6G frequency band. This paper introduces an innovative metasurface glass designed to enhance 5G mobile communication signals within the interior of glass windows. Through simulation and experimental validation, this design has demonstrated a signal enhancement of over 10dB within a 150mm range before and after the focal point, and 100mm in the vertical direction, compared to ordinary glass; at the focal point, the signal enhancement exceeds 15 dB. Furthermore, tests conducted across various real-world scenarios have confirmed that within areas covered by 5G signals, the RSRP of the signal at the focal point has increased by approximately 6-9 dB. In addition, the outer surface of this metasurface glass possesses low-emissivity characteristics, effectively blocking external infrared thermal radiation and reducing heat exchange with the interior of the glass window, thereby showing a significant advantage in maintaining a stable indoor temperature.

Increasing Efficiency in Furniture Remanufacturing with AHP and the SECI Model

This article proposes the application of the AHP method in an office furniture remanufacturing company, with the aim of optimizing knowledge retention and management. In particular, it seeks to establish the optimal retrieval route for returned products. To this end, a bibliographic analysis was first carried out, which revealed the scarcity of previous studies on the subject, thus validating the relevance of this work. Subsequently, a practical application of the AHP method was carried out to define the weighting matrix of the evaluation criteria, applied to three specific pieces of furniture, which confirmed the effectiveness of the tool. In a complementary manner, Nonaka and Takeuchi’s SECI model of knowledge management was used, guaranteeing the continuous updating of the matrices and the adequate retention of knowledge in the company. This methodology will increase the volume of remanufactured products and improve operating margins. By reaping both the economic and environmental benefits of this practice, the company will be able to reduce costs, generate additional revenue, improve its corporate image, and build customer loyalty. At the same time, this study promotes the sustainability and sustainable development of this practice within the company and, by extension, in the broader office furniture manufacturing industry. It can serve as a reference for other companies in this sector across different countries.

An orthogonal approach for analysis of underivatized steroid hormones using ultrahigh performance supercritical fluid chromatography-mass spectrometry (UHPSFC-MS).

The crucial role of steroid hormones in health and diseases merits their high-throughput, accurate and affordable measurements in biological specimens. Despite advances in analytical methods, sensing and quantifying steroid hormones remains challenging. Immunoassays offer excellent sensitivity but are inherently labour-intensive, costly, and prone to false positives. Mass spectrometry (MS) has been increasingly utilised, with the main hurdle being the isobaric tendencies of similar analytes, which complicates their separation and accurate quantification. This study compares ultrahigh-performance supercritical fluid chromatography separation (UHPSFC) and ultra-high-performance liquid chromatography (UHPLC) for MS detection. It optimises the column chemistry, temperature, and pressure to provide an operational protocol for the resolution and quantification of analytes. It presents the systematic characterisation of UHPSFC-MS performance by investigating spiked blood samples using Solid-Phase Extraction (SPE) and describes the matrix effects associated with MS measurements. Although both separation methods showed adequate resolution, specificity, and retention time, UHPSFC-MS was superior for five out of seven columns tested. With added high-throughput capacities, UHPSFC-MS, thus, offers an optimal solution for the analysis of steroid hormones for research, medical chemistry, and clinical diagnostics.

Extraction of high-quality moso bamboo fibers by enzyme/alkali synergistic mechanism

As an emerging non-wood resource, moso bamboo has attracted extensive attention because of its short growth cycle and high holocellulose content. However, the internal structure of moso bamboo is more compact than that of wood, leading to higher chemical consumption during the pulping process, which greatly reduces the quality of the extracted fibers. Herein, an innovative pulping system including enzymes and alkali is proposed to achieve higher-quality extraction of moso bamboo fibers. Benefiting from the synergistic effects of high-temperature and alkali-resistant cellulase, xylanase, and laccase, supplemented with alkaline pulping, adequate retention and softening of moso bamboo fibers were ultimately achieved. The sample treated with an enzyme/alkali system resulted in a relative increase in fiber length of 7.19 % and a 31.26 % increase in beating efficiency over alkaline pulping. In addition, the tensile index and tearing index of the paper treated with the enzyme/alkali system reached 50.17 N·m·g−1 and 9.12 mN·m2·g−1, which were 22.52 % and 20.53 % higher than those of the alkaline pulping, respectively. This work provides new insights into the production of high-performance moso bamboo fibers and paper with low energy and alkali consumption.

Comparative Analysis of Adaptation of Conventional and Printable Complete Denture Bases to the Underlying Casts - An In Vitro Stereomicroscopic Study.

Properly adapted complete denture bases will have adequate retention to the underlying oral mucosa. With technological advancement, there are various techniques of fabrication of complete dentures. There are studies regarding the marginal adaptation of conventional and CAD-CAM denture bases, but there is not enough research comparing the marginal adaptation and polymerisation shrinkage of conventional and 3D printed complete denture bases. In vitro study using stereomicroscopy to determine the marginal discrepancy between the denture base and the cast. Twelve gypsum casts were taken and divided into conventional and 3D-printed groups. Conventional denture bases were fabricated by adapting wax of 2 mm thickness which was subsequently processed whereas 3D printed bases were designed and the standard tessellation language (STL) files were used to print the denture bases. Three points were marked at the mid-palatal line and on both maxillary tuberosities. Digital images were then captured at the marked regions and were used to measure the maximum gap between the cast and denture base at the marked regions. Data were analysed using an independent t-test and one-way ANOVA. Conventional dentures had a significantly lesser marginal discrepancy than 3D printed dentures (P = 0.000). The left maxillary tuberosity showed the highest marginal discrepancy, significantly different from mid-palatal and right tuberosity sites. Conventional dentures perform better than their counterparts in terms of adaptation. This accurate adaptation is vital for the retention of the complete denture.

A DISTINCTIVE APPROACH TO REHABILITATE PATIENT WITH BILATERAL MAXILLECTOMY DEFECT BY TWO-PIECE HOLLOW OBTURATOR- CASE REPORT

An obturator is a common tool for prosthetic rehabilitation following invasive surgery, particularly in a total maxillectomy case. However, loss of teeth, palatal denture-bearing area, and vestibular retentive undercuts leaves an inadequate anatomic base to construct the definitive prosthesis. This results in compromised retention and stability. The retention problem can be resolved by fabricating an obturator that engages remaining undercuts. But in such acquired large defects, if all undercuts are engaged, the prosthesis may become too heavy, non-retentive, and challenging to insert, particularly in patients with very high and large defects. Therefore, in this case fabrication of two-piece magnet retained hollow obturator was described to make a prosthesis light weight with the use of thermoplastic polyvinyl chloride sheet in first part which provides adequate retention by engaging the desirable undercuts. The second part of the obturator was made hollow by the use of urinary catheter that was removed easily after completion of denture processing. After this, both the parts were attached together with the use of magnets. This technique is economical and easy to use to restore both function and esthetics in patients with bilateral maxillectomy defect.

A Dopamine-Modified Hyaluronic Acid-Based Mucus Carrying Phytoestrogen and Urinary Exosome for Thin Endometrium Repair.

Thin endometrium (TE) is closely associated with infertility in reproductive medicine. Estrogen therapy gains unsatisfactory outcomes. In this study, an artificial mucus based on dopamine (L-DOPA)-modified hyaluronic acid combining phytoestrogen cajaninstilbene acid and rat urinary exosomes (CUEHD) is constructed for TE treatment using a rat TE model. In the rat TE model, the dominant elastic behavior and adhesive properties of CUEHD guarantee adequate retention, rendering superior synergistic treatment efficacy and favorable biosafety characteristics. CUEHD treatment significantly increases endometrial thickness and promotes receptivity and fertility. Mechanistically, estrogen homeostasis, inflammation inhibition, and endometrial regeneration are achieved through the crosstalk between ER-NLRP3-IL1β and Wnt-β catenin-TGFβ-smad signaling pathways. Moreover, the therapeutic potential of exosomes from human urine and adipose tissue-derived stem cells (ADSCs) and rat ADSCs are also demonstrated, indicating extensive use of the artificial mucus system. Thus, this study illustrates a platform combining phytoestrogen and exosomes with promising implications for TE treatment.

Evaluating the Effectiveness of the "Double Finish Line Technique" on Full-Crown Retention for Short Abutments: An In Vitro Study.

Achieving clinically adequate retention for cast crowns in prepared short abutments represents a major challenge for practicing dentists. Despite the important developments with adhesive cement, only a few teeth can be treated this way, and conventional preparation techniques are still employed for most crowns. Numerous options for auxiliary features exist; however, there is no consensus about one preferred method. This study aimed to evaluate the effect of a new innovative technique called the "double finish line technique" on full-crown retention for short abutments and to compare it with another modified preparation method. A comparative in vitro experimental study was conducted at the Department of Fixed Prosthodontics, Damascus University. The study sample consisted of 30 chromium-cobalt abutments and 30 metal crowns. The sample was divided into three equal groups. The first group was a control group (CG) with a 20-degree total occlusal convergence, 3 mm height, and a 0.5 mm chamfer finish line. The second group had a reduced total occlusal convergence (TOC) in the cervical 1.5 mm of the axial wall from 20 to 8 degrees. The third group implemented the so-called "double finish line technique," adding another 0.5 mm chamfer finish line 1 mm above the first finish line (DFL group). The metal crowns were cemented to metal dies with zinc-phosphate cement. Pull-off tests were applied until failure. Data were analyzed, and the differences between the three groups were detected using one-way ANOVA followed by Bonferroni's post-hoc tests (p<0.05). The mean tensile strength values for the specimens were 115.36 (SD=14.59), 149.60 (SD=11.10), and 42.46 (SD=11.54) for the TOC, DFL, and CR groups, respectively. The reduced total occlusal convergence and double finish line techniques effectively increased full crown retention and resistance cemented on short abutments.

The Outcome Evaluation and Impact of Tele-mentoring Prison Medical Officers in Primary Care Psychiatry: A Model from Bihar, India

Introduction: As compared to the general population, prison inmates have a high prevalence of mental illness and substance use disorders. The authors designed and implemented a digitally driven, one-year primary care psychiatry program for medical officers in prison and correctional settings to address this need in Bihar, India. Aim: The study aimed to assess the outcome of training given to prison medical officers deputed by the Government of Bihar. Materials and Method: Five medical officers completed training out of the seven deputed. The training contained brief onsite (three-day) training in “Clinical Schedules for Primary Care Psychiatry” and three online (one-year) modules containing tele-psychiatric on-consultation training (tele-OCT), virtual classroom (VCR) sessions, and a public health module. We measured the outcome using translational quotient (TQ) and primary care psychiatry quotient (PCPQ), which were carried out 6 and 12 months after the onset of training. Results: The TQ scores in the first and second tele-OCT evaluations were 64% and 75.2% at 6 and 12 months of the course, suggesting adequate skill retention. Out of 33,565 consultations over 12 months, medical officers identified 2,947 psychiatric disorders requiring treatment, resulting in a PCPQ of 8.7%. Conclusion: Over a year, the training demonstrated efficacy in acquiring primary care psychiatry skills, and these competencies were applied in providing care for those with psychiatric disorders.

Preventing Cognitive Decline in Older Latino Adults With HIV Through a Culturally Tailored Health Promotion Intervention: Protocol for a Single-Arm Pilot Trial.

Older Latino adults with HIV are at increased risk for mild cognitive impairment and earlier onset of aging-related cognitive decline. Improvements in cognitive functioning and cognitive outcomes are possible among people with HIV who adopt health promotion behaviors. However, health promotion interventions for older Latino adults with HIV have not been extensively used or widely recognized as viable treatment options. Happy Older Latinos are Active (HOLA) is a multicomponent, health promotion intervention that is uniquely tailored for older Latino adults with HIV. This study aims to (1) determine the feasibility and acceptability of an adapted version of HOLA aimed at improving cognitive functioning among older Latino adults with HIV; (2) explore whether HOLA will produce changes in cognitive functioning; (3) explore whether HOLA will produce changes in activity, psychosocial functioning, or biomarkers of cognition; and (4) explore whether changes in activity, psychosocial functioning or cognitive biomarkers correlate with changes in cognition, while accounting for genetic risk for dementia. A single-arm pilot trial with 30 Latino (aged 50 years and older) men and women with HIV was conducted to assess feasibility, acceptability, and preliminary effects on cognition. Participants were assessed at 2 time points (baseline and postintervention) on measures of neurocognitive and psychosocial functioning. In addition, blood samples were collected to determine biomarkers of cognition at baseline and postintervention. Successful recruitment was defined as meeting 100% of the targeted sample (N=30), with 20% (n=6) or less of eligible participants refusing to participate. Adequate retention was defined as 85% (n=25) or more of participants completing the postintervention assessment and acceptability was defined as 80% (n=38) or more of sessions attended by participants. Participant recruitment began on February 22, 2022, and was completed on August 15, 2022. The last study visit took place on February 20, 2023. Data analysis is currently ongoing. Encouraging findings from this exploratory study may provide a blueprint for scaling up the HOLA intervention to a larger cohort of older Latino adults with HIV who may be currently experiencing or are at risk for HIV-related cognitive challenges. ClinicalTrials.gov NCT04791709; https://clinicaltrials.gov/study/NCT04791709. DERR1-10.2196/55507.

Perencanaan Kegiatan Retensi Rekam Medis di Rumah Sakit Islam Jakarta Pondok Kopi

Medical record retention (shrinkage) is the reduction of archives through the process of sorting documents 5 years after the patient dies or the last date of treatment. This study aims to plan medical record retention activities at RSIJ Pondok Kopi to overcome the problem of file accumulation, improve the efficiency of medical record management, and support better health services. This study uses a qualitative descriptive method and is sourced from 4 informants consisting of the head of medical records and medical record officers, in attracting informants using purposive sampling techniques. In the initial observation, the Jakarta Islamic Hospital Pondok Kopi has not resumed retention of medical records for the last 4 years due to hospital policies regarding service priorities. The results of this study indicate that RSIJ Pondok Kopi already has adequate retention SOPs, but has not retained medical records since 2020. This has resulted in the accumulation of medical record files in the storage room. Based on the results of the study, it can be concluded that RSIJ Pondok Kopi needs to immediately implement medical record retention to overcome the problem of file accumulation. The retention activity plan was made as input for retention so that it can overcome the problems in the medical record unit due to not having medical record retention.

The rehabilitation of a combined mid-facial defect using a magnetretained intra- and extra-oral prosthesis: a case report

There are several treatment options available to restore function and appearance in patients with combined mid-facial defects. Owing to the size of the defect and the associated size and weight of the prostheses, adequate retention can be challenging to achieve. Retention of a facial prosthesis can be improved using several techniques, such as medical grade adhesives, attachments, or osseo-integrated implants. For patients with a history of radiotherapy, surgical rehabilitation may be less favourable than non-surgical approaches owing to the risk of osteoradionecrosis and a reduced blood supply in the surgical fields. This clinical case report highlights the conservative rehabilitation of a combined mid-facial defect using a magnet-retained intra-oral and extra-oral prosthesis. CPD/Clinical Relevance: A thorough medical and clinical assessment will highlight factors that will influence the treatment planning process when managing a combined mid-facial defect.

Study protocol for a single-blind, parallel-group, randomized, controlled superiority trial of intensive versus weekly delivered prolonged exposure for adults with post-traumatic stress disorder

BackgroundProlonged exposure (PE) therapy is widely recognized as an effective treatment for post-traumatic stress disorder (PTSD) and is often considered one of the primary options for addressing this condition. Nevertheless, a significant proportion of patients (30–51%) fail to demonstrate clinically significant symptom changes. One of the reasons is that a high proportion of patients drop out from treatment, which often lasts for a minimum of 3–4 months. Hence, there is an urgent need for PTSD treatments that can be delivered to decrease dropout rates. A more intensive PE treatment approach has been suggested to decrease dropout rates and in addition achieve faster recovery rates and has shown promising effects on reducing PTSD symptoms but needs to be tested against firsthand treatment.MethodsThis single-blind, randomized controlled trial (N = 140) will compare an intensive delivery format of prolonged exposure (iPE) against standard weekly delivered sessions of PE. The primary outcome is change on the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Secondary outcomes include self-rated measures of symptoms of PTSD and complex PTSD, depression and quality of life, speed of recovery, cost effectiveness, dropout rates, and adverse events.DiscussionThis study will be the first to compare iPE with first-line treatment in a psychiatric outpatient setting. One of the key strengths of this study lies in its implementation within a clinical setting and the broad eligibility criteria. Additionally, the utilization of gold-standard assessment measures ensures the accuracy and reliability of the outcomes. However, several potential challenges may arise during the study’s execution. These challenges may include difficulties in participant recruitment, ensuring adequate participant retention, adherence to the treatment protocol, and maintaining therapist retention mostly due to recruitment taking place at one single clinic.Trial registration numberClinicaltrials.gov NCT05934175. Registered on June 6, 2023. Open Science Framework (OSF) https://osf.io/7qsb3. Registered on September 2, 2023.

Tamarind seed polysaccharide-metformin insert: Higher ocular retention, slow-release, and efficacy against corneal burn

Metformin (MET) can be an alternative therapeutic strategy for managing ocular burn primarily because of its pleiotropic mechanism. Longer retention on the ocular surface and sustained release are necessary to ensure the efficacy of MET for ocular application. Although the high aqueous solubility of MET is good for formulation and biocompatibility, it makes MET prone to high nasolacrimal drainage. This limits ocular residence and may be a challenge in its application. To address this, polymers approved for ophthalmic application with natural origin were analyzed through in silico methods to determine their ability to bind to mucin and interact with MET. An ocular insert of MET (3 mg/6 mm) was developed using a scalable solvent casting method without using preservatives. The relative composition of the insert was 58 ± 2.06 %w/w MET with approximately 14 %w/w tamarind seed polysaccharide (TSP), and 28 %w/w propylene glycol (PG). Its stability was demonstrated as per the ICH Q1A (R2) guidelines. Compatibility, ocular retention, drug release, and other functional parameters were evaluated. In rabbits, efficacy was demonstrated in the 'corneal alkali burn preclinical model'. TSP showed potential for mucoadhesion and interaction with MET. With adequate stability and sterility, the insert contributed to adequate retention of MET (10–12 h) in vivo and slow release (30 h) in vitro. This resulted in significant efficacy in vivo.

A New Hyaluronic Emulgel of Hesperetin for Topical Application-An In Vitro Evaluation.

The present study aimed to formulate and characterize a hesperetin formulation to achieve adequate deposition and retention of hesperetin in the epidermis as a target for some cosmetic/dermatological actions. To derive the final emulgel, various formulations incorporating different proportions of Polysorbate 80 and hyaluronic acid underwent testing through a Box-Behnken experimental design. Nine formulations were created until the targeted emulgel properties were achieved. This systematic approach, following the principles of a design of experiment (DoE) methodology, adheres to a quality-by-design (QbD) paradigm, ensuring a robust and purposeful formulation and highlighting the commitment to a quality-driven design approach. The emulsions were developed using the phase inversion method, optimizing the emulgel with the incorporation of hyaluronic acid. Physically stable optimized emulgels were evaluated for their globule size, surface charge, viscosity, pH, electrical conductivity, and hesperetin content. These assays, along with the temperature swing test, were used to select the optimal formulation. It was characterized by a droplet size, d[4,3], of 4.02 μm, a Z-potential of -27.8 mV, an O/W sign, a pH of 5.2, and a creamy texture and proved to be stable for at least 2 months at room temperature. Additionally, in vitro release kinetics from the selected emulgel exhibited a sustained release profile of hesperetin. Skin assays revealed adequate retention of hesperetin in the human epidermis with minimum permeation. Altogether, these results corroborate the promising future of the proposed emulgel in cosmetic or dermatological use on healthy or diseased skin.

Novel motivational interviewing-based intervention improves engagement in physical activity and readiness to change among adolescents with chronic pain.

Engaging adolescents with chronic pain in physical activities is challenging. Motivational interviewing (MI) combined with activity promotion may encourage teens to make behavioural changes. This research aimed to assess the feasibility and acceptability of our MI-based physical activity promotion programme, the M3 training. In our exploratory study with 35 adolescent-parent dyads, we evaluated the feasibility by enrolment, drop-out and retention rates. Acceptability of the M3 training was examined by adherence rates and participation experiences through open-ended questions. We also assessed changes in pain self-efficacy and readiness to change after the M3 training intervention. The M3 training was feasible with an adequate enrolment (77.8%) and retention (85.7%) rate. Both teens and parents found the M3 training acceptable and considered exercise and physical activity the most helpful elements of the programme (36% and 37%, respectively). While self-efficacy remained unchanged, we identified a significant increase in the readiness to change for adolescents and parents. M3 training improved physical activity engagement while prioritising adolescents' autonomy. Furthermore, it appears to be a clinically relevant approach and could result in a positive shift in readiness to change within a shorter timeframe. The preliminary version of the M3 training was reviewed and commented upon by the public (adolescents and adults). Adolescents who participated in this study were designing their own movement programme, considering their lived experiences. Participants' feedback was used to create the online version of the M3 training (which will be published elsewhere).

Study on the Impact of Population and Economic Activities on Environmental Indicators through Pca

Principal Component Analysis (PCA) is applied in environmental policy planning to effectively identify and assess key factors affecting carbon peaking and emissions reduction. By analysing multidimensional data covering GDP, population, average temperature, oil consumption and price, and CO2 emissions, PCA reveals complex correlations of environmental challenges. Preliminary regression analyses expose complex relationships between variables, with a particular focus on anomalous oil consumption data for 2020, emphasising the importance of precise analytical methods.The PCA highlights the significant impacts of economic activity, population and oil-related factors on environmental indicators by simplifying the high-dimensional data, retaining the key information, and extracting the principal components with the highest variance.The KMO and Bartlett test confirms the applicability of PCA, with variance interpretation and dendrograms guiding principal component selection to ensure adequate retention of data information. This approach enabled precise identification of factors affecting environmental indicators, construction of a weighted composite model to quantitatively analyse environmental impacts on a yearly basis, and strengthened the understanding of the overall role of population and economic activities on the environment. Overall, the application of PCA highlights its key role in refining complex environmental data, clarifying the drivers of carbon emissions and energy consumption, and in the development of targeted environmental policies, enriching the environmental planning toolkit and demonstrating the contribution of statistical techniques to environmental governance.

Improving the Retention of Maxillary Complete Denture: A Case Report

Complete dentures play an essential role in restoring oral function and improving the quality of life for individuals who have missing all their normal teeth. One of the key factors determining the success of complete dentures is their retention, which refers to the ability of dentures to stay securely in place during normal oral function. Adequate retention is essential for proper speech, mastication and overall comfort of the denture wearer. The study aimed to improve the retention of complete dentures through three different approaches: spacer, posterior palatal seal area, and undercut area. Three dentures were fabricated using the same steps, with variations in certain steps based on the retention technique being employed. The study showed that all three dentures had improved retention compared to standard complete dentures. The dentures that included the posterior palatal seal area and spacer demonstrated higher retention than the denture that employed the undercut technique. It is worth noting that the patient did not find the denture with the undercut technique satisfactorily.

Care4Parents: An Evaluation of an Online Mindful Parenting Program for Caregivers of Children with 22q11.2 Deletion Syndrome

Abstract Objectives Parenting a child with special healthcare needs is associated with significant caregiver stress. Previous research has found that parenting stress and mental health impact outcomes for children with chronic illnesses. Despite this, the importance of managing parents’ stress is often overlooked in the management of chronic health conditions, such as 22q11.2 deletion syndrome (22q11DS). The objective of this study was to investigate the acceptability of the mindful parenting program, Care4Parents. Methods This study was designed as a non-randomised pilot study evaluating the acceptability of an online mindful parenting program Care4Parents, specifically designed for those parenting a child with special health care needs, including medical complexity. There were 20 participants recruited to take part, which involved attending eight online weekly group sessions for 2 h, with a follow-up after 2 months and practice exercises between sessions. Interviews were conducted with 12 participants after the completion of the program. Using attendance data and thematic analysis of semi-structured interviews, the study aimed to determine if the online program Care4Parents would be experienced by participants as acceptable. Results Results indicate preliminary evidence of acceptability, with adequate retention and themes emerging from interviews highlighting the appropriateness of content, delivery, and perceived benefits, including personal growth, peer support, and enhanced coping. ‘Barriers to engagement’ was also a theme, and adjustments were discussed based on participant feedback to further enhance the program. Conclusions The analysis of the data indicates that the program was deemed acceptable to participants, therefore warranting further research using quantitative measures to confirm findings and investigate effectiveness.