ABSTRACT The cancer diagnosis is currently experiencing an alteration of molecular biomarkers using s paradigm for the diagnostic panel. One of the most important genomic datasets showing genetic sequences is the classification of lung cancer. Many research studies have been conducted in this area, but none of them yields satisfied outcomes on account of lower classification accuracy. At first, the data are collected through the lung cancer dataset. Afterward, data are fed into pre-processing. The pre-processing segment removes the noise and enhances the input images utilising Dynamic Context-Sensitive Filtering. The pre-processing output is fed to the feature extraction segment. Here, four statistical features are extracted based on the Force Invariant Improved Feature Extraction Model. The extracting features are fed to the feature segmentation segment. Lung cancer images can segment the ROI region using Adaptive Density-Based Spatial Clustering. After that, the segmentation features are given to ACWGAN for effectively categorizing cancer and non-cancer of the lung cancer Hence, the Hunter–prey optimisation algorithm is employed to optimise the ACWGAN classifier. It classifies the lung cancer images accurately. The LCC-ACWGAN-HPOA-CTI algorithm is activated in MATLAB under the lung cancer database. The performance of the LCC-ACWGAN-HPOA-CTI approach shows higher accuracy and lower computation time than those of the existing methods.