You have accessJournal of UrologyCME1 Apr 2023PD41-10 AQUABLATION FOR BPH-RELATED LUTS: FUNCTIONAL AND ENDOSCOPIC RESULTS UP TO TWO YEARS AFTER THE INTERVENTION Sabrina De Cillis, Daniele Amparore, Stefano De Luca, Enrico Checcucci, Federico Piramide, Michele Sica, Alberto Piana, Gabriele Volpi, Paolo Verri, Juliette Meziere, Davide Zamengo, Giovanni Busacca, Alberto Quarà, Edoardo Cisero, Marco Colombo, Dalia Cidda, Cecilia Gatti, Michele Ortenzi, Andrea Sterrantino, Matteo Manfredi, Cristian Fiori, and Francesco Porpiglia Sabrina De CillisSabrina De Cillis More articles by this author , Daniele AmparoreDaniele Amparore More articles by this author , Stefano De LucaStefano De Luca More articles by this author , Enrico CheccucciEnrico Checcucci More articles by this author , Federico PiramideFederico Piramide More articles by this author , Michele SicaMichele Sica More articles by this author , Alberto PianaAlberto Piana More articles by this author , Gabriele VolpiGabriele Volpi More articles by this author , Paolo VerriPaolo Verri More articles by this author , Juliette MeziereJuliette Meziere More articles by this author , Davide ZamengoDavide Zamengo More articles by this author , Giovanni BusaccaGiovanni Busacca More articles by this author , Alberto QuaràAlberto Quarà More articles by this author , Edoardo CiseroEdoardo Cisero More articles by this author , Marco ColomboMarco Colombo More articles by this author , Dalia CiddaDalia Cidda More articles by this author , Cecilia GattiCecilia Gatti More articles by this author , Michele OrtenziMichele Ortenzi More articles by this author , Andrea SterrantinoAndrea Sterrantino More articles by this author , Matteo ManfrediMatteo Manfredi More articles by this author , Cristian FioriCristian Fiori More articles by this author , and Francesco PorpigliaFrancesco Porpiglia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003346.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We report our clinical experience with Aquablation with endoscopic evaluation at 3 months and 1 year after the procedure and perioperative and 2-year functional outcomes. METHODS: In this prospective study, with enrolment from 10/2018 to 10/2020, the inclusion criteria were patients with BPH-related LUTS, International Prostate Symptom Score (IPSS) ≥10, prostate volume<80 mL and maximum micturition rate (Qmax) ≤12 mL/s. Demographic data, perioperative data and complications (according to the Clavien-Dindo system) were collected. Functional outcomes were assessed at 1, 3, 6, 12 and 24 months with uroflowmetry, post-void residual assessment (PVR), IPSS, Sexual Health Inventory for Men (SHIM) and Male Sexual Health Questionnaire for ejaculatory dysfunction (MSHQ-EjD). In addition, patients underwent cystoscopy at 3 and 12 months after the surgical procedure to evaluate the quality of the ablation was assessed according to a Likert scale (1-poor; 5-excellent). In addition, the preservation of the veru montanum, the presence of residual fluffy tissue or mucosal flaps and ureteral orifices, and the presence of scar tissue at the level of the bladder trigone were assessed. RESULTS: 56 patients were enrolled in the study. Preoperative median Qmax, IPSS, QoL score and mean PVR were respectively 8 (2,4) ml/s, 22 (16-28), 4 (3-5) and 76 (9,8) ml. The median ablation time was 5.12 (2.13) min. The median catherization time and hospital stay were 3 (3-4) and 4 (4-5) days, respectively. We recorded 3 postoperative complications classified as Clavien-Dindo grade >2 (5.3%), namely 1 (1.7%) acute urinary retention after catheter removal and 2 (3.5%) anemia requiring transfusion. At 3-month and 12-months follow-up cystoscopy in 15/56 (26.7%) patients non-obstruent mucosal flap was shown, but no damage to the verumontanum as well as no residual fluffy tissue, ureteral orifices or bladder trigone were recorded. The median quality of the ablation was 3 (3-4). The median IPSS urinary symptom score was 4 (2-6) after 1 month and further improved to 2 (1-4) two year after surgery. Concurrently, the median IPSS QoL score and mean PVR reached 0 (0-1) and 18,9 ml (22,7) at 24 months. The mean Qmax was 19.7 (9.3), 18.1 (3.1), 18.2 (6.2), 17.5 (6.1) and 18.1 (6.6) ml/s at 1, 3, 6, 12 and 24 months, respectively. No patients developed postoperative erectile dysfunction, while 3 (5,4%) reported loss of antegrade ejaculation. CONCLUSIONS: Endoscopic and functional results demonstrate that Aquablation is a safe, feasible and effective procedure for the treatment of BPH-related LUTS up to 2 years follow up. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1062 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Sabrina De Cillis More articles by this author Daniele Amparore More articles by this author Stefano De Luca More articles by this author Enrico Checcucci More articles by this author Federico Piramide More articles by this author Michele Sica More articles by this author Alberto Piana More articles by this author Gabriele Volpi More articles by this author Paolo Verri More articles by this author Juliette Meziere More articles by this author Davide Zamengo More articles by this author Giovanni Busacca More articles by this author Alberto Quarà More articles by this author Edoardo Cisero More articles by this author Marco Colombo More articles by this author Dalia Cidda More articles by this author Cecilia Gatti More articles by this author Michele Ortenzi More articles by this author Andrea Sterrantino More articles by this author Matteo Manfredi More articles by this author Cristian Fiori More articles by this author Francesco Porpiglia More articles by this author Expand All Advertisement PDF downloadLoading ...