Acute Respiratory Infections In Young Children Research Articles

Analysis of Risk Factors for Acute Respiratory Infections in Toddlers

Acute Respiratory Infection (ARI) is still one of the most common health problems caused mortality is currently high and become global concern. Diseases that attack the respiratory tract organs are caused by various factors, both internally and externally. The purpose of this study was to identify risk factors for the incidence of ARI in young children or called toodlers aged 1-5 years at the Abepura Health Center, Jayapura City. The research method used quantitative research with a cross sectional study which was carried out in January-June 2021. The research population was 937 mothers with toddlers and 90 mothers as the samples was taken by slovin formula. Data were collected through interviews using a questionnaire. Data analysis was univariate and bivariate using Chi-Square test. The results of the study found that as many as 24 toddlers (26.7%) suffered from ARI. Factors that have a significant relationship with the incidence of ARI in children under five are nutritional status of children (p-value = 0.000 < 0.05; RP = 7.16; 95% CI = (3.79 – 13.52), immunization status (p-value = 0.002 < 0.05; RP = 3.16; 95% CI = (1.69-5.89) and family smoking habits (p-value = 0.000 < 0.05; RP = 23.14; CI95% = (5 .83 – 91.82. Meanwhile, the factor of exclusive breastfeeding (p-value = 0.766 > 0.05; RP = 1.23; 95% CI = 0.60 – 2.52) was not found to be associated with the incidence of ARI. The local health center is advised to improve communication, information and education programs for mothers about the importance of maintaining nutritional status and providing complete immunizations and an approach to families to suppress smoking habits that can affect the health of toddlers.

Virological Surveillance and Molecular Characterization of Human Parainfluenzavirus Infection in Children with Acute Respiratory Illness: Germany, 2015-2019.

Human parainfluenza viruses (HPIVs) are important causes of respiratory illness, especially in young children. However, surveillance for HPIV is rarely performed continuously, and national-level epidemiologic and genetic data are scarce. Within the German sentinel system, to monitor acute respiratory infections (ARI), 4463 respiratory specimens collected from outpatients < 5 years of age between October 2015 and September 2019 were retrospectively screened for HPIV 1–4 using real-time PCR. HPIV was identified in 459 (10%) samples. HPIV-3 was the most common HPIV-type, with 234 detections, followed by HPIV-1 (113), HPIV-4 (61), and HPIV-2 (49). HPIV-3 was more frequently associated with age < 2 years, and HPIV-4 was more frequently associated with pneumonia compared to other HPIV types. HPIV circulation displayed distinct seasonal patterns, which appeared to vary by type. Phylogenetic characterization clustered HPIV-1 in Clades 2 and 3. Reclassification was performed for HPIV-2, provisionally assigning two distinct HPIV-2 groups and six clades, with German HPIV-2s clustering in Clade 2.4. HPIV-3 clustered in C1, C3, C5, and, interestingly, in A. HPIV-4 clustered in Clades 2.1 and 2.2. The results of this study may serve to inform future approaches to diagnose and prevent HPIV infections, which contribute substantially to ARI in young children in Germany.

Effect of in-house crowding on childhood hospital admissions for acute respiratory infection: A matched case–control study in Bangladesh

ObjectiveDespite previous studies conducted to identify potential household factors, no conclusive evidence exists regarding the effect of in-house crowding on hospitalization for acute respiratory infection (ARI) in Bangladesh. Hence, the aim of this study was to detect such an association in children aged 6–59 months. MethodsAn age and sex-matched case–control study was conducted involving 348 children in Bangladesh. In-house crowding was measured by people-per-bedroom. Conditional logistic regression was performed to identify the association between in-house crowding and hospitalization for ARI. ResultsIn-house overcrowding was associated with a 2.9-fold (95% confidence interval 1.80–4.73) greater adjusted odds of hospitalization for ARI compared to children from less crowded houses. In-house overcrowding was common in rural areas and in households with a poor economic status. Suboptimal breastfeeding and household tobacco smoke exposure were found to prevail in overcrowded households. ConclusionIn-house overcrowding is associated with an increased risk of hospitalization for ARI in young children. Eliminating the fraction of the ARI burden due to in-house overcrowding will rely on increasing awareness regarding indoor air pollution and ventilation in the house and making efforts to avoid smoking in dwellings. Along with the management of crowding, child nutrition and exclusive breast-feeding requirements should be continued for a wide range of child health benefits.

Prevalence of acute respiratory infections among children under five years of age attending rural health training centre of Era’s Lucknow Medical College and Hospital

Background: Every year ARI in young children is responsible for an estimated 3.9 million deaths worldwide. About 90 percent deaths are due to Pneumonia which is usually bacterial in origin. By low-cost interventions such as hand washing, breast feeding, accessibility of rapid and attainable methods of early diagnosis of ARI, can help to reduce its burden. Improving the primary medical care services and developing better methods for early detection, treatment and where possible, prevention of acute respiratory infection is the best strategy to control ARI. The aim of the study was to estimate prevalence of ARI among children under-5 years of age attending Rural Health Training Centre of Era’s Lucknow Medical College and Hospital.Methods: The present study was carried out from Nov.2015 to April 2016 covering 305 children below 5 years from RHTC of Era’s Lucknow Medical College and Hospital. Children with acute respiratory infection (ARI) having symptoms like cough, running nose, sore throat, nasal congestion or breathing difficulty were included in the study.Results: Out of 305 children under 5 years, 43 (14%) were diagnosed with ARI. The overall prevalence of ARI was 14% with 95%CI (10.20-18.0). According to social class, prevalence of ARI was higher in low socioeconomic class 42.96%.Statistically no significance between social class and prevalence of ARI was seen with Chi sq test: 0.879, t= 0.928.Overcrowding were present in 33% of cases with 95% CI (17.2-48.80). Inadequate ventilation 48% with 95% CI (31.21-64.79), and uses of smoky chullah 49% with 95% CI (31.21-64.79). Prevalence of ARI was more prevalent in children with malnutrition 52.9%. Statistically high association was seen between ARI status and nutritional status, with Chi squre test:18.3, t≤0.001.Conclusions: The study concludes that malnutrition, low socioeconomic status, poor nutritional status, maternal illiteracy, overcrowding, and inadequate ventilation were the major social and demographic risk factors responsible for ARI in under five children. Minimizing these risk factors and by cost effective interventions one can significantly reduce the prevalence of ARI in the rural community.

The burden of community-managed acute respiratory infections in the first 2-years of life.

Contemporary information on acute respiratory infections (ARIs) in children is based on hospital cohorts, primary healthcare presentations, and high-risk birth cohort studies. We describe the burden and determinants of symptomatic episodes of ARIs in unselected healthy infants in the first 2-years of life. One hundred and fifty-four infants from subtropical Brisbane, Australia participated in a longitudinal, community-based birth cohort study. A daily tick-box diary captured pre-defined respiratory symptoms. Parents also completed a burden diary, recording family physician and hospital visits, and antibiotic use. Participants contributed 88,032 child-days (78.2% of expected), of which 17,316 (19.7%) days were symptomatic during 1,651 ARI episodes: incidence rate 0.56 ARIs per child-month (95%CI: 0.54, 0.59). Runny nose (14,220 days; 6.0-days median duration) and dry cough (6,880 days; 4.0-days median duration) were reported most frequently. Overall, 955 burden diaries recorded 455 family physician visits (1-8 visits per ARI) and 48 hospital presentations, including six hospital admissions. Antibiotics were prescribed on 209 occasions (21.9% of ARI episodes where burden diary submitted). Increasing age, non-summer seasons, and attendance at childcare were associated with an increased risk of ARI. ARIs are a common cause of morbidity in the first 2-years of life, with children experiencing 13 discrete ARI episodes and almost 5-months of respiratory symptoms. Most ARIs are managed in the community by parents and family physicians. Antibiotic prescribing remains common for ARIs in young children. Secular societal changes, including greater use of childcare in early childhood, may have maintained the high ARI incidence in this age-group. Pediatr Pulmonol. 2016;51:1336-1346. © 2016 Wiley Periodicals, Inc.

The pattern of antibiotic administration for toddlers and infants with acute respiratory infections (Mashhad- Iran)

ABSTRACT Background: Acute respiratory infections (ARI) are the main cause for antibiotic (AB) use in all age groups specially the first two years of life. The local information about the pattern of AB prescription in ARI is a necessary part for any program which aims logical use of AB. The current study was designed to find the frequency and types of AB administration for ARI in young children (<2years) in Mashhad, Iran. Method: This is an observational cohort study which was started in November 2005 and ended up at May 2006. The study group was composed of 1000 infants between 6 month and 20 months old. The children were followed monthly by telephone calls (up to six month after the first interview) and were asked about signs and symptoms of acute respiratory infection and systemic antibiotic use during each month. Results: The average monthly incidence of ARI was 34.5% in the study population, 66.3 %( mean) of the children with ARI were visited by a doctor, which led to AB prescription in 32.7 %( mean) of times. The frequency of inject able antibiotics was almost two times of oral Abs, and benzatin penicillin was the most prescribed AB (54%of all Abs). Conclusion: The rate of AB administration for infants with ARI is not very high in Mashad, but the frequency of AB injections is unacceptable.

A Study Of Epidemiological Factors Related To Acute Respiratory Infection (ARI) In Under Five Children Attending The Immunization Clinic Of Calcutta National Medical College And Hospital

A Study Of Epidemiological Factors Related To Acute Respiratory Infection (ARI) In Under Five Children Attending The Immunization Clinic Of Calcutta National Medical College And Hospital

Human metapneumovirus infections among children with acute respiratory infections seen in a large referral hospital in India

Background Acute respiratory infections (ARI) are the leading cause of morbidity and mortality among children <5 years of age in developing countries. Human metapneumovirus (hMPV), a newly described respiratory pathogen, has been identified as an important cause of ARI in young children. Objectives The objective was to describe the prevalence of hMPV in children who presented with ARI to a large referral hospital in Delhi, India and to genotype circulating strains on the basis of F gene nucleotide sequence analysis. Study design We analyzed 97 samples from children <5 years of age with ARI seen at the All India Institute of Medical Sciences from June 2004 to March 2005. RT-PCR was performed for the N and F genes and partial F gene nucleotide sequences were used to characterize the viruses. Results hMPV was identified in 12% of children with ARI, including 13% of the children hospitalized with ARI. Most virus identification occurred in the winter. The Indian strains clustered in the A2 genetic sublineage. Conclusions This report establishes hMPV as an important cause of ARI in children in India.