Acute Effect Of Resistance Exercise Research Articles

Acute Effects of High-Intensity Resistance Exercise on Recognition of Relational Memory, Lactate, and Serum and Plasma Brain-Derived Neurotrophic Factor.

Baumgartner, NW, Belbis, MD, Kargl, C, Holmes, MJ, Gavin, TP, Hirai, DM, and Kao, S-C. Acute effects of high-intensity resistance exercise on recognition of relational memory, lactate, and serum and plasma brain-derived neurotrophic factor. J Strength Cond Res XX(X): 000-000, 2024-Acute aerobic exercise improves memory, but this phenomenon is understudied in response to resistance exercise (RE) despite evidence that RE-induced increases in lactate and brain-derived neurotrophic factor (BDNF) play mechanistic roles in memory performance. To determine the acute effect of RE on lactate, BDNF, and their associations with object and relational memory, blood lactate, and serum and plasma BDNF were taken from 36 adults (average age 23.64 ± 3.89 years; 18 woman) before and immediately after 42 minutes of high-intensity RE and a rest condition on counterbalanced days. Subjects then immediately studied a series of paired objects and completed object and relational recognition tasks. Results revealed a condition by trial interaction, previously studied objects were remembered less accurately following RE (d = 0.66) but recognition occurred faster (d = 0.28), indicating a speed-accuracy tradeoff following RE. There was no effect of either intervention on relational recognition performance. Lactate (d = 3.68) and serum BDNF (d = 0.74) increased following RE, whereas there was no time-related change in lactate and serum BDNF following rest. However, changes in lactate and BDNF did not predict any measures of object (rs < 0.25, ps > 0.16) or relation recognition (rs < 0.28, ps > 0.13). Collectively, these findings suggest that acute high-intensity RE selectively improves the processing speed of recognizing objects at the cost of less accurate recognition of previously studied objects. Furthermore, changes in object and relational memory performance are unlikely driven by acute increases in lactate or BDNF following high-intensity RE.

Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients

BackgroundHemodialysis (HD) per se is a risk factor for thrombosis. Considering the growing body of evidence on blood-flow restriction (BFR) exercise in HD patients, identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training model. The aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise (RE) with BFR on this molecule. MethodsTwo hundred and six HD patients volunteered for this study (all with a glomerular filtration rate of <15 mL/min/1.73 m2). The RE + BFR session consisted of 50% arterial occlusion pressure during 50 min sessions of HD (intradialytic exercise). RE repetitions included concentric and eccentric lifting phases (each lasting 2 s) and were supervised by a strength and conditioning specialist. ResultsSeveral variables were associated with elevated levels of D-dimer, including higher blood glucose, citrate use, recent cardiovascular events, recent intercurrents, higher inflammatory status, catheter as vascular access, older patients (>70 years old), and HD vintage. Furthermore, RE + BFR significantly increases D-dimer after 4 h. Patients with borderline baseline D-dimer levels (400–490 ng/mL) displayed increased risk of elevating D-dimer over the normal range (≥500 ng/mL). ConclusionThese results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE + BFR. D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE + BFR.

Effect of a single resistance exercise session on inflammatory markers and oxidative stress in women living with HIV

People living with HIV (PLH), who use antiretroviral therapy (ART), are more susceptible to changes in the inflammatory profile and oxidative stress, and women have greater access to ART. Although physical exercise is a complementary strategy to treatment due to its antioxidant and anti-inflammatory effects, it is not clear whether acute responses to exercise can be harmful to PLH. The aim of the study was to investigate the acute effect of resistance exercise (RE) on inflammatory and oxidative stress markers in PLH. Ten women, using ART, performed RE session consisting of seven exercises for the whole body. For biochemical evaluation, blood samples were collected before (pre), 1 hour (1h) and 2 hours (2h) after the RE session. One-way ANOVA followed by Bonferroni's post hoc test was used to compare results between time points. There was an increase only in markers, GSSG of 160% (pre: 0.40 ± 0.11; 1h: 1.18 ± 0.36; 2h: 1.04 ± 0.25 mmol/g), TNF-α of 98 % (pre: 4.60 ± 0.55; 1h: 6.95 ± 0.77; 2h: 9.10 ± 1.03 pg/ml) and 52% IL-6 (pre: 2.47 ± 0 .67; 1h: 3.63 ± 1.26; 2h: 5.38 ± 2.15 pg/ml). The other variables remained unchanged (P &gt; 0.05). It is concluded that a RE session increased the levels of inflammatory markers and oxidative stress in PLH in a non-exacerbated way.

Acute effect of resistance exercise at different velocities on stiffness and vascularity of the biceps brachii muscle: a preliminary study.

Resistance exercise can be defined as the percentage of maximal strength (%1 repetition maximum) used for a particular exercise. Shear wave elastography (SWE) is a robust and novelty imaging technique that provides information regarding tissue stiffness. Superb microvascular imaging (SMI) is a non-irradiating technique that can provide quantitative measurement of muscle blood flow non-invasively. To compare the acute effects of low- and high-velocity resistance exercise on stiffness and blood flow in the biceps brachii muscle (BBM) using SWE and SMI. This prospective study included 60 healthy men (mean age=28.9 years; age range=26-34 years). BBM stiffness was measured by using SWE at rest, after low- and high-velocity resistance exercise, and muscle blood flow was also evaluated by SMI. Resistance exercise was performed using a dumbbell with a mass adjusted to 70%-80% of one-repetition maximum. The stiffness values increased significantly from resting to high- and low-velocity resistance exercises. There was no significant difference between the elastography values of the BBM after the high- and low-velocity resistance exercise. The blood flow increased significantly from resting to high- and low-velocity resistance exercises. Blood flow increase after low-velocity exercise was significantly higher compared to high-velocity exercise. While muscle stiffness parameters and blood flow significantly increased from resting after both high- and low-velocity resistance exercises, blood flow significantly increased after low-velocity exercise compared to high-velocity exercise. This can mean that metabolic stress, an important trigger for muscle development, is more likely to occur in low-velocity exercise.

Acute effect of resistance exercise on anaerobic threshold in type 2 diabetic individuals

Introduction: Type 2 Diabetes Mellituscan promote changes in the cardiac autonomic nervous system, during exercise and even in the recovery period, and can alter the lactic metabolism of individuals with this pathology. One way to assess these changes is through blood lactate collection. Objective: to investigate the acute effect of resistance exercise on lactic metabolism in diabetic individuals. Methods: The sample consisted of 14 diabetic individuals and 10 apparently healthy individuals, of both sexes. The anaerobic threshold was determined during the knee extension exercise (Roman table) and two tests were applied: one with 10% below and the other with 10% above the LA, each lasting one minute, maintaining spontaneous breathing. and without apnea. Results: The results of our study showed that there were more significant changes in lactate measured by blood from 30% of 1RM for the CG as well as for the DM2 group, the latter with more expressive changes when also compared with the loads of 40 and 50% of 1RM. Conclusion: Diabetic individuals tend to suffer greater and lesser metabolic stress when compared to apparently healthy individuals.

Acute Effect of Resistance Exercise on Mucociliary Clearance in Active Smokers

Background: Nasal mucociliary clearance (NMC) responds to autonomic activity through exercise. However, there is a gap in the literature on how NMC responds to resistance exercise. Objective: To evaluate the acute effects of resistance tube exercise on NMC and the autonomic nervous system in smokers. Methods: Clinical trial was performed with 18 individuals. Personal, anthropometric, and smoking history data were collected, and a pulmonary function test was performed by spirometry. The fatigue resistance test was performed in order to [...]

Acute Effect of Resistance Exercise on Serum Cortisol and its Correlation to Blood Glucose in Healthy Non Obese Adults: A Pilot Study

Introduction: Different types and intensity of resistance training/ exercises lead to variable cortisol responses, which is essential for growth and homeostasis on short term and long term basis. But the variable responses are not accurately defined to be of any help in tailoring one’s exercise program. Aim: To study the effect of resistance exercise on serum cortisol and its correlation to blood glucose in healthy non obese subjects. Materials and Methods: It was an experimental analytical pilot study extending from February 2017-July 2018 involving 48 healthy non obese subjects (24 males and 24 females) of age group 18-25 years, were enrolled in the study after the screening protocol. High volume exercise training regimen was used involving major muscle group of arms, legs and trunk. Regime involved five exercises with three sets. Between each set, subjects took 30 seconds rest and with each exercise, a rest period of one minute. Height, weight were measured to calculate Body Mass Index (BMI) and serum blood glucose was done along with serum cortisol. Results: The serum cortisol levels in males in pre-exercise group was 145.47±33.67 μg/dL while postexercise group had 116.57±34.40 μg/dL reflecting moderately significant decrease (p&lt;0.01). The serum cortisol levels in females in pre-exercise group were 141.83±38.38 μg/dL while in postexercise group 118.46±35.53 μg/dL with a moderately significant decrease (p&lt;0.01). The Random Blood Sugar (RBS) levels in both males and females postexercise was significantly increased (p&lt;0.05). There was decrease in serum cortisol levels in comparison to rise in RBS in both genders, a highly significant decrease (p&lt;0.001) in males in comparison to moderately significant decrease (p&lt;0.05) in females. Conclusion: Resistance exercise induced decrease in cortisol hormone and its interplay with serum glucose can be better understood by multivariate/elaborate studies on a large sample size.

EFFECT OF EXERCISE WITH CONTINUOUS AND INTERMITTENT BLOOD FLOW RESTRICTION ON HEMODYNAMICS

ABSTRACT Introduction: Strength training with blood flow restriction (BFR) involves the use of low loads (20-30% of 1RM) with restriction of blood flow to promote gains in physical fitness. The restriction can be applied continuously or intermittently; however, it is unclear how it affects the hemodynamics of hypertensive women. Objective: To analyze the acute effect of resistance exercise (RE) on the upper and lower limbs with continuous and intermittent blood flow restriction (BFR) on the hemodynamic variables of women with hypertension. Methods: Thirteen women with controlled hypertension (40 to 65 years) underwent eight experimental protocols, with a randomized, counter balanced, crossover design; four exercise sessions for the right upper limb (elbow flexion) and four for the right lower limb (knee extension). The systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and heart rate (HR) were measured before, during, immediately after and 15, 30, 45 and 60 minutes after the exercises. Results: There were no significant interactions between the protocols vs. segments vs. time, protocols vs. segments, protocols vs. time, segments vs. time, protocol, segment and time, on the variables SAP, DAP, and HR during and after the RE (p&gt;0.05). Although all these protocols had significantly elevated SAP, DAP and HR, the values remained within the normal range. The protocols of this study did not cause hypotensive effect. Conclusion: Low-load RE combined with continuous and intermittent BFR, on the upper and lower limbs, appears to promote similar variations in the hemodynamic variables of women with hypertension. Level of evidence II; Randomized clinical trial.

The acute effect of resistance exercise on limb blood flow.

What is the central question of this study? How does resistance exercise affect peripheral haemodynamics in the active and inactive limb? What is the main finding and its importance? Preliminary data indicate that resistance exercise increases flow and shear rate in the active limb transiently. The same exercise has minimal, short-lasting influence on peripheral haemodynamics in the inactive limb, but further research is required to elaborate on resistance exercise-mediated changes in vascular function in active and inactive limbs. Current evidence indicates that to achieve maximum health benefits, regular resistance exercise should be a key component of structured physical activity. Several studies have revealed that regular resistance exercise may be associated with impaired vascular function, although this finding is inconsistent. Proposed explanations for impairment include substantial increases in blood pressure and increased retrograde blood flow in active limbs promoted by resistance exercise. However, few studies have examined the acute haemodynamics of resistance exercise in active - and even fewer in inactive - limbs. The purpose of this study was to characterise the haemodynamic responses in peripheral arteries in active and inactive limbs in response to resistance exercise using upper and lower limbs. Ten participants (five male, five female) familiar with resistance training performed three sets of 10 isotonic repetitions of right-sided bicep curls or knee extensions on separate days. Blood flow, shear rate and muscle oxygenation in the active and inactive limb, and blood pressure were measured before and for 3min after each set. Blood flow increased in response to resistance exercise in the active limb (∼8-fold and ∼6-fold for the upper and lower limb respectively), with concurrent significant increases in mean and antegrade shear rate. In the inactive limb, blood flow more than doubled for both upper and lower limb exercise, transiently, with no significant change in retrograde shear rate. These acute blood flow profiles following resistance exercise are not indicative of long-term vessel impairment based on current understanding of blood flow and shear stress patterns.

Acute effect of resistance exercise on cognitive function in people living with HIV

People living with HIV are at an increased risk of developing cognitive deficits. Physical exercise is an important strategy to improve the brain health of people living with HIV. This randomized, controlled study aimed to investigate the acute effect of a single resistance exercise session on the cognitive function of people living with HIV. Twenty-three people living with HIV were randomized (1:1) to a control group (n = 12) or the exercise group (n = 11). Cognitive function was assessed by the Stroop test and the Trail Making Test. The exercise group was evaluated before and after the exercise session; meanwhile, the control group was evaluated before and after a 40-minute rest period. No statistical difference was found on the effect of exercise on cognitive function (p > 0.05). This result suggests that one session of resistance exercise was not capable of improving the cognitive function of people with HIV.

Acute effect of resistance exercise using the German Volume Training Method on blood pressure of prehypertensive subjects

Acute effect of resistance exercise using the German Volume Training Method on blood pressure of prehypertensive subjects

Temporal increase in muscle cross-sectional area as an acute effect of resistance exercise in resistance-trained and untrained individuals

The purpose of this study was to compare the temporal increase in muscle cross-sectional area (CSA) as the acute response of resistance exercise (RE) between resistance-trained and untrained groups and investigate the factors that affect the muscle CSA. Resistance-trained ( n = 14) and untrained ( n = 14) subjects performed four kinds of triceps brachii RE. Muscle CSA and intracellular hydration (IH), were measured prior to and 5-, 30-, and 60-minute after RE. Pearson's correlation coefficient was calculated to clarify the relationships among percent increases in muscle CSA and IH, area under the Oyx-Hb curve, blood lactate concentration, and % maximum voluntary contraction (MVC)-root-mean-square (RMS) of electromyogram (EMG). At 5-minute after RE, muscle CSA increased significantly to 120.2 ± 6.3% in the resistance-trained group and 105.5 ± 2.3% in the untrained group ( p < .01). However, neither group showed a significant difference between the values before and 30-minute after RE. In the resistance-trained group, there was a significant increase in IH at 5-minute post-RH ( p < .01), and correlations were found between percent increases in muscle CSA and IH ( r = 0.70, p < .01), area under the Oxy-Hb curve ( r = 0.77, p < .01), and % MVC-RMS of EMG ( r = 0.72, p < .01). The findings of this study suggest that measurements of muscle CSA in studies of muscle hypertrophy should be performed 30-minute or more after the last resistance exercise session, and muscle pump exercises should be conducted just before participation in bodybuilding, and physique contests.

Acute effect of resistance exercise performed at different intensities on urine loss in older women

IntroductionTo evaluate the acute effect of resistance exercise performed at different intensities (moderate and vigorous) on urine loss in older women with mixed and stress urinary incontinence.MethodsThe total of 16 older women with urinary incontinence underwent 2 sessions of resistance exercises involving different muscle groups. In a balanced crossover design, 1 of the 2 exercise intensities (12 or 6 repetitions maximum, RM) was applied in each session. The pad test was used to assess urine loss in the 2 sessions, with a weight increase of 2 g as the criterion. Differences in the pad test results between the sessions were compared with the use of the Wilcoxon test.ResultsThe mean pad weight was 0.69 ± 0.94 g at the intensity of 12RM and 0.50 ± 0.53 g at 6RM. In accordance with the cut-off adopted (2 g), only 2 of the 16 women lost urine. No significant difference in the pad test results (&lt;i&gt;p&lt;/i&gt; = 0.975) was observed between the 2 resistance exercise intensities.ConclusionsResistance exercise performed at different intensities (moderate and vigorous) did not cause urine loss in older women with urinary incontinence.

Acute effect of resistance exercise on arterial stiffness in healthy young women

Acute effect of resistance exercise on arterial stiffness in healthy young women

Acute effect of a resistance exercise session on markers of cartilage breakdown and inflammation in women with rheumatoid arthritis.

To assess the acute effect of resistance exercise (RE) on circulating biomarkers of cartilage breakdown and inflammation in women with rheumatoid arthritis (RA). Thirty-four volunteers (17 with and 17 without RA), participated in a 25 min RE session (knee extension, knee flexion, hip abduction and hip adduction) with one set of 12 repetitions at 50% of one repetition maximum (1RM) and one set of eight repetitions at 75% of 1RM. Blood samples were collected 30 and 5 min before, immediately after and 1, 2 and 24 h after the session. We used analysis of variance for repeated-measures with Bonferroni adjustments to assess differences between groups over time. In both groups we found significant changes in interleukin (IL)-1 beta (P = 0.045), IL-1 receptor antagonist (IL-1ra) (P < 0.001), IL-10 (P = 0.004), IL-6 (P < 0.001) and cartilage oligomeric matrix protein (COMP) P < 0.001) in response to exercise, but no changes in tumor necrosis factor-alpha and C-reactive protein levels. We found no differences in the responses of the two groups to the session, except for COMP levels, which are more sensitive to exercise and rest effects in RA patients. Women with and without RA have similar changes in response to a RE session in levels of inflammation biomarkers, but not of cartilage breakdown. IL-10 and IL-1ra increased after the RE session, indicating that RE may have an acute anti-inflammatory effect. Additional studies are necessary to clarify if repeated RE sessions can have long-term anti-inflammatory effects and the possible clinical repercussions of this cartilage breakdown characteristic in response to exercise in RA patients.

Acute effects of resistance exercise on affect, arousal, and urge to drink in temporarily abstinent young adult hazardous drinkers.

Young adults frequently engage in hazardous alcohol consumption, and many meet the diagnostic criteria for an alcohol use disorder. The urge to drink is a defining symptom of alcohol dependence, and it is closely tied to and exacerbated by negative affect. This study examined the acute effect of resistance exercise on affect, arousal, and drinking urges in young adult (ages 21-40) hazardous drinkers. On two separate occasions, 14 participants underwent an 18-hour alcohol abstinence before completing, in a counter-balanced manner, a 20-minute session of resistance exercise and a 20-minute video control. Significant improvements in affect (t = 2.07, p = .04) and arousal (t = 4.09, p < .01), but not urge to drink, were found with exercise. Single sessions of resistance exercise can positively alter affect and arousal during alcohol abstinence. Practical exercise interventions designed to alter affect and arousal could potentially alter drinking. (Am J Addict 2016;25:623-627).

Acute effect of resistance exercise performed at different intensities on the hemodynamics of normotensive men

&lt;p&gt;The aim of this study was to investigate the acute effect of resistance exercise performed at different intensities on the hemodynamics of normotensive men. The study included 10 normotensive and recreationally-trained men (25.40 ± 6.90 years) performed the following three experimental protocols in a randomized order: a) 60% of 8RM; b) 80% of 8RM; c) 100% of 8RM. All protocols performed six exercises (Leg Press, Vertical Bench Press, Leg Flexion, Close-Grip Seated Row, Leg Extension and Shoulder Press) with three sets of eight repetitions for each exercise. Systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and double product (DP) were measured at rest, at the end of exercise and during the 60-minute post-exercise. The findings showed that there was a significant reduction in the faster SBP with a longer duration (&lt;em&gt;p&lt;/em&gt;&amp;lt; 0.0001) for the 100% of 8RM intensity, but without significant decreases in DBP for all intensities (&lt;em&gt;p&lt;/em&gt;&amp;gt; 0.05). There were significantly higher elevations in HR and DP for 100% of 8RM at all times (&lt;em&gt;p&lt;/em&gt;&amp;lt;0.0001). We conclude that high intensities (100% of 8RM) promote post-exercise hypotension with faster responses and greater duration and increase HR and DP in normotensive men.&lt;/p&gt;

Acute Response of PGC-1α and IGF-1 Isoforms to Maximal Eccentric Exercise in Skeletal Muscle of Postmenopausal Women.

PGC-1α4, a novel isoform of the transcriptional coactivator PGC-1α, was recently postulated to modulate the expression of anabolic and catabolic genes and therefore regulate skeletal muscle hypertrophy. Resting levels of PGC-1α4 messenger RNA (mRNA) expression were found to increase in healthy adults after resistance training. However, the acute effect of resistance exercise (RE) on PGC-1α4 expression in populations prone to progressive muscle loss, such as postmenopausal women, has not been evaluated. Here, we investigated alterations in mRNA expression of PGC-1α4 and PGC-1α1, a regulator of muscle oxidative changes, in postmenopausal women after high-intensity eccentric RE and analyzed these findings with respect to changes in insulin-like growth factor (IGF)-1 and catabolic gene expression. Nine postmenopausal women (age, 57.9 ± 3.2 years) performed 10 sets of 10 maximal eccentric repetitions of single-leg extension with 20-second rest periods between sets. Muscle biopsies were obtained from the vastus lateralis of the exercised leg before and 4 hours after the RE bout with mRNA expression determined by quantitative real-time polymerase chain reaction. No significant changes in the mRNA expression of either PGC-1α isoform were observed after acute eccentric RE (p > 0.05). IGF-1Ea mRNA expression significantly increased (p ≤ 0.05), whereas IGF-1Eb and mechano-growth factor (MGF) did not significantly change (p > 0.05). PGC-1α4 mRNA expression was associated with reduced mRNA expression of the catabolic gene myostatin (R = -0.88, p < 0.01), whereas MGF mRNA expression was associated with reduced mRNA expression of the catabolic gene FOXO3A (R = -0.81, p ≤ 0.05). These data demonstrate an attenuated response of PGC-1α isoforms to an acute bout of maximal eccentric exercise with short rest periods in postmenopausal women.

The acute effect of resistance exercise with blood flow restriction with hemodynamic variables on hypertensive subjects.

The purpose of this study was to analyze systolic blood pressure (SBP), diastolic blood pressure (DBP) and the heart rate (HR) before, during and after training at moderate intensity (MI, 50%-1RM) and at low intensity with blood flow restriction (LIBFR). In a randomized controlled trial study, 14 subjects (average age 45±9,9 years) performed one of the exercise protocols during two separate visits to the laboratory. SBP, DBP and HR measurements were collected prior to the start of the set and 15, 30, 45 and 60 minutes after knee extension exercises. Repeated measures of analysis of variance (ANOVA) were used to identify significant variables (2 × 5; group × time). The results demonstrated a significant reduction in SBP in the LIBFR group. These results provide evidence that strength training performed acutely alters hemodynamic variables. However, training with blood flow restriction is more efficient in reducing blood pressure in hypertensive individuals than training with moderate intensity.

Acute resistance exercise with blood flow restriction effects on heart rate, double product, oxygen saturation and perceived exertion.

The aim of this study was to compare the acute effect of resistance exercise (RE) with and without blood flow restriction (BFR) on heart rate (HR), double product (DP), oxygen saturation (SpO2 ) and rating of perceived exertion (RPE). Twenty-four men (21·79±3·21years) performed three experimental protocols in a random order (crossover): (i) high-intensity RE at 80% of 1RM (HI), (ii) low-intensity RE at 20% of 1RM (LI) and (iii) low-intensity RE at 20% of 1RM combined with partial blood flow restriction (LI+BFR). HR, blood pressure, SpO2 and RPE were assessed. The data were analysed using repeated measures analysis of variance and the Wilcoxon test for RPE. The results indicated that all protocols significantly increased HR, both immediately postexercise and during the subsequent 60min (P<0·05), and postexercise DP (P<0·05), but there were no differences between protocols. The protocols of LI and LI+BFR reduced postexercise SpO2 (P=0·033, P=0·007), and the LI+BFR protocol presented a perception of greater exertion in the lower limbs compared with HI (P=0·022). We conclude that RE performed at low intensity combined with BFR seems to reduce the SpO2 after exercise and increase HR and DP while maintaining a perception of greater exertion on the lower limbs.