When utilizing high-dimensional chaotic signals for frequency modulation, achieving a uniformly distributed power spectrum is a challenging task. This paper addresses this challenge by proposing a power spectrum homogenization strategy based on distribution transformation. The strategy transforms the task of achieving a uniformly distributed power spectrum in frequency modulation of high-dimensional chaotic signals to solve and equalize the probability density function of the chaotic signals, thereby further enhancing the ability of high-dimensional chaotic signals to suppress electromagnetic interference. Firstly, the difficulty of obtaining a smooth probability density function of chaotic modulation signals is solved using the kernel density estimation algorithm. Then, a distribution transformation algorithm is proposed to convert non-uniformly distributed chaotic modulation signals into uniformly distributed chaotic modulation signals. By using uniformly distributed chaotic modulation signals for frequency modulation, the objective of power spectrum equalization is achieved. Finally, taking the Chua’s chaotic signal as an example, the effectiveness of the proposed strategy is verified using an experimental platform based on a digital signal processor-controlled active clamping flyback converter.