Acetabular Sclerosis Research Articles

The childhood arthritis radiographic score of the hip: the proposal cut-off value using cluster analysis.

Juvenile idiopathic arthritis (JIA) is a chronic rheumatic disease that affects children. It is crucial to detect and treat hip involvement in JIA early to prevent functional impairment and reduced quality of life. The Childhood Arthritis Radiographic Score of the Hip (CARSH) is a validated radiographic scoring system used to assess hip involvement in JIA. In this study, we aimed to determine cut-off values for CARSH scores using cluster analysis. The study was conducted as a cross-sectional analysis and included JIA patients with hip involvement who underwent a pelvic radiograph. The same pelvic radiograph was interpreted by two experienced pediatric rheumatologists at baseline and after 3weeks by both readers for reliability. The CARSH scores were calculated for each hip four times (twice by each reader). For the 50 hips, a total of 200 interpretations of the CARSH score were obtained. Model-based clustering was employed to identify distinct groups of CARSH score interpretations and characterize the phenotype of each cluster. Twenty-five children with hip involvement were included. The mean age was 13.9 ± 4.6years. JIA subtypes were as follows: ERA in 64%, oligoarthritis in 16%, psoriatic arthritis in 12%, polyarthritis RF + in 4%, and RF - in 4% of patients. For the 200 hip interpretations, three clusters based on the level of the CARSH were identified by model-based clustering. Cluster 1 consisted of 17 CARSH score interpretations with a median score of 7 ± 3 (ranging from 1 to 15). This group primarily comprised patients with enthesitis-related arthritis (ERA) and psoriatic arthritis. Patients in cluster 1 were generally older, experienced longer diagnostic delays, and had a longer disease duration compared to the other clusters. Cluster 2 exhibited a moderate CARSH score, with an average score of 4 ± 3 (1 to 15). Patients in this group had significantly higher body weight compared to the other clusters. Cluster 3 represented the group with the least severe hip involvement, characterized by CARSH scores of 2 ± 1 (ranging from 0 to 9). This cluster had a higher proportion of male patients and higher C-reactive protein (CRP) levels than the other clusters. Regarding the individual items of the CARSH score, cluster 1 showed higher percentages of hip radiograph abnormalities such as joint space narrowing, erosions, growth abnormalities, and subchondral cysts. Cluster 2 was characterized by a high rate of acetabular sclerosis, with little to no abnormalities in other CARSH score items. Cluster 3 was the only group that exhibited hip subluxation, with minimal abnormalities in the other score items. In conclusion, this study identified three distinct groups of CARSH scores, representing varying levels of severity in hip involvement in JIA. These findings provide valuable insights for clinicians in assessing and managing JIA patients with hip involvement, enabling tailored treatment strategies based on the severity of the condition. Key Points • While a Childhood Arthritis Radiographic Score of the Hip (CARSH) is a valid and reliable tool in hip-related juvenile idiopathic arthritis, its use is limited in daily practice due to the lack of available cut-off values. • The cluster analysis defined three clusters based on the CARSH levels. • Cluster 1 exhibited the highest score with more damage and disability. Cluster 2 involved a moderate score and more overweight patients. Cluster 3 included the least level of the score but with an active disease parameter.

Incidencia de displasia del desarrollo de cadera. Estandarizando la radiografía con un dispositivo anti rotatorio «Orthohip»

IntroductionDevelopmental dysplasia of the hip is a pathology that causes functional sequelae if it is missed or misdiagnosed. AP radiography of the pelvis is the method most used for screening; however, multiple variables alter the result; positioning, environment, patient, etc. The objective was to determine the incidence of developmental dysplasia of the hip using the anti-rotational device, evaluating the agreement between observers with quantitative and qualitative parameters in the radiograph for diagnosis. Materials and methodsRetrospective observational study of historical cohort including patients between 4 and 9 months of age with AP radiography of the pelvis using the anti-rotational device evaluating only simple dysplasia. For the measurement, the CareStream program and the concordance analysis with the Stata 15 program were used. ResultsOne hundred eighty-one radiographs of patients were included, with an incidence of developmental dysplasia of the hip of 9.4% (95% CI: 5.5–14.6), where 29.4% were bilateral, 35.3% of the right hip and 35.3% of the left hip, taking into account 3 or more qualitative parameters, such as the lateral acetabular sclerosis, flat acetabular configuration, line in the external metaphysis, and an irregular rim. A good degree of agreement (kappa greater than 0.6) was found in acetabular sclerosis, left acetabular line and in the final diagnosis (kappa 0.8). DiscussionThe standardization of radiography taking with the use of an anti-rotational device «Orthohip» and qualitative parameters additional to the acetabular index facilitates an adequate diagnosis avoiding the taking of multiple radiographs.Level of evidence: Level III.

Effects of types and degrees of ankylosing spondylitis hip structural damages on post-total hip arthroplasty outcome measurements.

To determine the effects of ankylosing spondylitis (AS)-associated hip damages on the outcome measurements after total hip arthroplasty (THA).The medical records of 122 patients with AS (181 hips) who underwent THA were retrospectively reviewed. The mean follow-up was 43.9 (32-129) months. The types and degrees of hip damages were evaluated by preoperative hip X-rays. The patients were grouped according to the satisfaction degree after the operation. Univariable and multivariable statistical analyses were conducted.The intraclass correlation coefficients for the assessment between the 2 reviewers in the study were 0.86 to 0.97. Cox regression showed that femoral head erosion severity had an effect on the recovery time of independent walking without crutches postoperatively (odds ratio = 1.467, 95% confidence interval: 1.050-2.409, P = .025). The mean time to recover independent walking in the severe femoral head erosion group was 7.3 ± 0.9 weeks, which was 4.6 ± 0.4 weeks longer than in the non-severe femoral head erosion group, as confirmed by the log-rank (Mantel-Cox) test (Chi-squared = 11.684, P = .001). The multivariable analysis showed that higher acetabular sclerosis scores correlated with lower postoperative dissatisfaction risk (odds ratio = 0.322, 95% confidence interval: 0.136-0.764). The multiple linear regression analysis showed that postoperative range of motion (ROM) improvement was affected by preoperative ROM of the hip, space narrowing degree, and ceramic-ceramic material for the weight-bearing surface (F = 179.81, P < .001), with preoperative ROM of the hip having the greatest impact.Severe femoral head erosion prolongs the recovery time of independent walking after THA. Acetabular sclerosis is not associated with poor outcomes in patients with AS-associated hip damage undergoing THA.

Malignant Fibrous Histiocytoma Associated With Diaphyseal Medullary Stenosis

An unusual presentation of secondary malignant fibrous histiocytoma of the femur in a patient with diaphyseal medullary stenosis is described. The patient, a 42-year-old man, presented with a painful lump in the right knee. A radiograph of the right femur showed lytic destruction. Characteristic features of longitudinal linear striations in the metaphysis and medullary stenosis in the diaphysis were observed in radiographs of the long tubular bones. A radiograph of the pelvis showed bilateral acetabular bone scleroses. After chemotherapy, surgical resection was done. On light microscopic examination, the tumor had features characteristic of malignant fibrous histiocytoma. Specimens from the diaphyseal medullary stenosis from the femur and tibia showed typical features of bone infarction. Radiographs of other members of the patient's family showed similar features of linear striation, cortical bone thickening, and acetabular sclerosis, including wavy, open growth plate of the iliac crest. The patient's aunt had died of a bone sarcoma in the shoulder region. It is important to recognize this extremely rare clinicopathologic type of diaphyseal medullary stenosis that frequently is associated with secondary high-grade sarcomas.

Reliability of radiographic assessment in hip and knee osteoarthritis

Objective: To evaluate the reproducibility of commonly used radiographic measures in hip and knee OA and to overcome certain limits of existing knowledge on their reliability from previous studies.Design: Three readers evaluated 100 hip joints (50 pelvic X-rays) and 100 antero-posterior and lateral knee films of a hospital-based sample of patients with radiographic OA at two time points 3 months apart. They retrospectively estimated the presence and severity of joint specific individual radiographic features (osteophyte formation and joint space narrowing at different sites, cysts, subchondral sclerosis, bony deformity and chondrocalcinosis) and two different overall scores. Within and between observer reproducibility was calculated by intra-class correlation coefficient.Results: At the hip joint excellent intra- as well as inter-observer reliability for superior joint space narrowing (JSN) and femoral head deformity could be demonstrated, while the assessment of medial JSN, osteophytes and acetabular sclerosis depends on the level of the investigator’s experience. At the knee joint, femorotibial and patellofemoral osteophytes showed a high intra- and inter-observer reliability. Grading of JSN is highly reader dependent; rating of subchondral sclerosis and chondrocalcinosis does not seem to be reproducible enough. The overall scores showed an excellent reproducibility both at hip and knee joints.Conclusion: A reliable radiographic severity grading of hip and knee OA is possible with the application of global scores and individual features, if joint specific items are selected and readers are trained enough.

Cementless Total Hip Arthroplasty With Autologous Bone Grafting for Hip Dysplasia

The fate of autologous femoral head bone grafts in acetabular roof reconstruction for severely dysplastic hips was investigated in 25 patients (25 cementless total hip arthroplasties). Twenty patients were women and 5 were men, whose average age was 55 years old; their average followup was 58 months. The average Harris Hip Rating improved from a preoperative value of 49 points to a postoperative value of 85 points. Radiographic measurements did not indicate any vertical or horizontal socket migration >2 mm. The grafted bone was incorporated by an average time of 7 months, and the acetabular sclerosis had disappeared in 23 hips by 9.4 months. One year after operation, the grafted bone was reduced in size significantly. Radionuclide uptake at the site of the bone graft remained high for as long as 18 months after the operation, then normalized. The autologous acetabular bone grafts were incorporated completely and remodeled 18 months after surgery.