Particle Image Velocimetry (PIV) has become a standardized measurement technique in the field of experimental research both in academic and industrial environments with applications covering the breadth of fluid dynamics. The metrology’s success must be ascribed to its non-intrusive nature together with its intrinsic simplicity and ability to retrieve vast amounts of instantaneous spatial velocity information (order of giga- to terabytes) relative to the short operation time (order of seconds). While the majority of PIV image processing related studies have been aimed so far at improving the accuracy of the fluid velocities extraction, PIV image analysis involving arbitrarily moving bodies has received limited to no attention. Notwithstanding, it is expected that great advances can be made in the field of fluid-structure interactions by improving the technique’s measurement capabilities as a direct result of enhanced image analyses. Interfaces are encountered in many engineering applications. Flow over moving or stationary rigid surfaces (boundary layers, turbomachinery, aerofoils), deformable surfaces (pulmonary and arterial flows, morphing wings, flexing membranes), interfacial/multiphase flows (bubbles, waves, free surface turbulence) are all examples of fluid-structure-related problems where the primary concerns are either the transport of momentum across or near the surface, the interactive coupling between fluid motion and surface deformation, or both. Although Computational Fluid Dynamics (CFD) has made considerable progress over the last decades, the inherent modelling of the fluid-structure interactions remains at the forefront of CFD development necessitating high resolution and reliable experimental verification. From both an experimental and image analysis point of view, it is considered a worldwide challenge to obtain reliable, accurate PIV velocity measurements with sufficient resolution near dynamic surfaces. This fundamental limitation of PIV has driven typical experiments to be restricted to fields of view, free of interfaces or other boundaries. The inhibition to characterize the coupling between boundary motion and fluid forces consequently hampers a proper understanding of the underlying physics. This presents a very stringent limitation in the study of aero- or hydro-elastic effects. Being scientifically important, future PIV development should therefore drive towards ameliorating the measurement capability close to dynamic interfaces in spite of the accompanying difficulties. Particle Image Velocimetry allows the measurement of flow velocity of air or water by injecting microseed particles. Being illuminated, these tracer particles reflect the light which is recorded by a specialised camera. A spatial section of the investigated flow is illuminated at two sequential time instances. High-energy light sources, typically lasers, are capable of light pulse durations in the order of nano-seconds and ensure sharp tracer images. Comparison of the two image recordings then enables the calculation of the displacement of the particles’ images and thus the 2D (or 3D depending on the camera arrangement) velocity components of the flow in which they are transported. Nowadays, the acronym PIV embodies a collection of imaging methodologies but all are based on the original operational principle.