The optimal development of tourism clusters (quite active and effective, but not allowing overtourism) requires the development of methods for calculating their level of development and potential, taking into account the most important influencing factors. Consideration of the share of factors’ influence on the development of tourism clusters does not adequately take into account the infrastructure and urban planning components. This article, based on a literature analysis and expert assessment, identifies the main factors influencing the development of tourism clusters and shows the leading role of infrastructure factors and the provision of a cluster with high-quality hotel stock. Formulas are given for calculating factor indicators and determining the integral level of development of the cluster, as well as its development potential, including infrastructural. An example of calculations of the development potential of a cluster and management decisions made in the field of construction is given using the example of an emerging tourism cluster, “Kirzhach”. The results of the factor analysis and calculation of the cluster development potential will allow informed management decisions to be made not only for the investment and construction of hotel real estate and other tourism infrastructure, but also for cluster development priorities and areas of government regulation and support.