Accommodative Error Research Articles

Reduced Monocular Accommodation Abilities with Laptop Usage Under Scotopic Ambient Illumination

Laptops are widely used even in dark scotopic rooms. This study compares monocular accommodation statuses with laptop usage under three illuminations. Thirty university students read on a laptop for 5 minutes under scotopic, mesopic, and photopic conditions. The monocular amplitude of accommodation, accommodation facility, and accommodation error are measured for each illumination. Repeated measure ANOVA shows a significant difference in the amplitude, facility, and error between different illuminations [F (1.49, 43.18) = 10.61, p<0.001], [F (1.65, 36.30) = 6.78, p=0.005] and [F (2, 56) = 3.65, p=0.032]. Scotopic illumination reduces monocular accommodation abilities with laptop usage.

Ocular accommodation and wavelength: The effect of longitudinal chromatic aberration on the stimulus-response curve.

The longitudinal chromatic aberration (LCA) of the eye creates a chromatic blur on the retina that is an important cue for accommodation. Although this mechanism can work optimally in broadband illuminants such as daylight, it is not clear how the system responds to the narrowband illuminants used by many modern displays. Here, we measured pupil and accommodative responses as well as visual acuity under narrowband light-emitting diode (LED) illuminants of different peak wavelengths. Observers were able to accommodate under narrowband light and compensate for the LCA of the eye, with no difference in the variability of the steady-state accommodation response between narrowband and broadband illuminants. Intriguingly, our subjects compensated more fully for LCA at nearer distances. That is, the difference in accommodation to different wavelengths became larger when the object was placed nearer the observer, causing the slope of the accommodation response curve to become shallower for shorter wavelengths and steeper for longer ones. Within the accommodative range of observers, accommodative errors were small and visual acuity normal. When comparing between illuminants, when accommodation was accurate, visual acuity was worst for blue narrowband light. This cannot be due to the sparser spacing for S-cones, as our stimuli had equal luminance and thus activated LM-cones roughly equally. It is likely because ocular LCA changes more rapidly at shorter wavelength and so the finite spectral bandwidth of LEDs corresponds to a greater dioptric range at shorter wavelengths. This effect disappears for larger accommodative errors, due to the increased depth of focus of the eye.

Higher order aberrations and retinal image quality during short-term accommodation in myopic and non-myopic children.

Despite the known associations between near work and myopia, and retinal image quality and eye growth, accommodation-induced changes in higher order aberrations (HOA's) and retinal image quality in children with different refractive errors are poorly understood. Ocular HOA's were measured using a Hartmann-Shack wavefront sensor (COAS-HD, Wavefront Sciences) in 18 myopic and 18 age- and sex-matched non-myopic children during short-term accommodation tasks (four demands of 0, 3, 6 and 9 D) presented using a Badal optometer. Eighth order Zernike polynomials were fitted across a 2.3 mm pupil diameter to determine refractive power vectors (M, J180 and J45 ) and the accommodation error, and a 4 mm pupil was used for HOA analyses. Retinal image quality was examined using the visual Strehl ratio based on the optical transfer function (VSOTF) for third to eighth radial orders only. Most refractive error group differences were observed for the 6 and 9 D demands. Myopic children underwent greater changes in with-the-rule astigmatism (J180 ), higher order and third order RMS values, primary vertical ( ) and horizontal coma ( ), and several other individual Zernike coefficients compared with non-myopic children (all refractive error group by demand interaction p-values of ≤0.02). Non-myopic children exhibited a greater negative shift in primary ( ) and positive shift in secondary spherical aberration ( ) (both refractive error group by demand interaction p-values of ≤0.002). The VSOTF degraded for the 6 and 9 D demands in both groups, but the myopic children underwent a greater mean (SE) reduction from 0 D of -0.274 (0.048) for the 9 D demand, compared with -0.131 (0.052) for the non-myopic children (p = 0.001). These results may have implications for the association between near work, accommodation and myopia development, particularly related to the use of short working distances during near tasks.

Effect of multifocal spectacle lenses on accommodative errors over time: Possible implications for myopia control.

The study purpose was to improve understanding of how multifocal spectacle lenses affect accommodative errors and whether this changes over time. Fifty-two myopes aged 18 to 27 years were allocated randomly to one of two progressive addition lens (PAL) types with 1.50 D additions and different horizontal power gradients across the near-periphery boundary. Lags of accommodation were determined with a Grand Seiko WAM-5500 autorefractor and a COAS-HD aberrometer for several near distances with the distance correction and the near PAL correction. For the COAS-HD the neural sharpness (NS) metric was used. Measures were repeated at three-month intervals over 12 months. At the final visit, lags to booster addition powers of 0.25, 0.50, and 0.75 D were measured. Except at baseline, both PALs' data were combined for analysis. For the Grand Seiko autorefractor, both PALs reduced accommodative lag at baseline compared with SVLs (p < 0.05 and p < 0.01 at all distances for PAL 1 and PAL 2, respectively). For the COAS-HD, at baseline PAL 1 reduced accommodative lag at all near distances (p < 0.02), but PAL 2 only at 40 cm (p < 0.02). Lags measured with COAS-HD were greater for shorter target distances with PALs. After 12 months' wear, the PALs no longer reduced accommodative lags significantly, except at 40 cm distance, but 0.50 D and 0.75 D booster adds decreased the lags to those measured at baseline or less. In conclusion, for PALs to reduce accommodative lag effectively, addition power should be tailored to typical working distances and after the first year of wear should be boosted by at least 0.50 D to maintain efficacy.

Optical modelling of an accommodative light field display system and prediction of human eye responses.

The spatio-angular resolution of a light field (LF) display is a crucial factor for delivering adequate spatial image quality and eliciting an accommodation response. Previous studies have modelled retinal image formation with an LF display and evaluated whether accommodation would be evoked correctly. The models were mostly based on ray-tracing and a schematic eye model, which pose computational complexity and inaccurately represent the human eye population's behaviour. We propose an efficient wave-optics-based framework to model the human eye and a general LF display. With the model, we simulated the retinal point spread function (PSF) of a point rendered by an LF display at various depths to characterise the retinal image quality. Additionally, accommodation responses to the rendered point were estimated by computing the visual Strehl ratio based on the optical transfer function (VSOTF) from the PSFs. We assumed an ideal LF display that had an infinite spatial resolution and was free from optical aberrations in the simulation. We tested points rendered at 0-4 dioptres of depths having angular resolutions of up to 4x4 viewpoints within a pupil. The simulation predicted small and constant accommodation errors, which contradict the findings of previous studies. An evaluation of the optical resolution on the retina suggested a trade-off between the maximum achievable resolution and the depth range of a rendered point where in-focus resolution is kept high. The proposed framework can be used to evaluate the upper bound of the optical performance of an LF display for realistically aberrated eyes, which may help to find an optimal spatio-angular resolution required to render a high quality 3D scene.

Design of a dual focal-plane near-eye display using diffractive waveguides and multiple lenses.

We propose a method to construct a compact dual focal-plane optical see-through near-eye display using diffractive waveguides and multiple lenses. A virtual image from a display device is projected into a three-grating waveguide using an objective lens, and a virtual image can be shown at a far distance with an extended eye box. One negative lens is employed to reduce the focus distance of the virtual image, and a corresponding positive lens is used to compensate for the distortion and accommodation errors. Thus, not only can a virtual image with a near distance be achieved, but also a virtual plane with a further distance can be generated by introducing another projection module and waveguide. Only two waveguides and two pieces of lenses are used in front of one eye to obtain a lightweight outlook. To verify the proposed method, a proof-of-concept prototype was developed to provide vivid virtual images at different depths in front of the human eye.

Accommodation lags are higher in myopia than in emmetropia: Measurement methods and metrics matter.

PurposeTo determine whether accommodative errors in emmetropes and myopes are systematically different, and the effect of using different instruments and metrics.MethodsSeventy‐six adults aged 18–27 years comprising 24 emmetropes (spherical equivalent refraction of the dominant eye +0.04 ± 0.03 D) and 52 myopes (−2.73 ± 0.22 D) were included. Accommodation responses were measured with a Grand Seiko WAM‐5500 and a Hartmann–Shack Complete Ophthalmic Analysis System aberrometer, using pupil plane (Zernike and Seidel refraction) and retinal image plane (neural sharpness—NS; and visual Strehl ratio for modulation transfer function—VSMTF) metrics at 40, 33 and 25 cm. Accommodation stimuli were presented to the corrected dominant eye, and responses, referenced to the corneal plane, were determined in the fellow eye. Linear mixed‐effects models were used to determine influence of the refractive group, the measurement method, accommodation stimulus, age, race, parental myopia, gender and binocular measures of heterophoria, accommodative convergence/accommodation and convergence accommodation/convergence ratios.ResultsLags of accommodation were affected significantly by the measurement method (p < 0.001), the refractive group (p = 0.003), near heterophoria (p = 0.002) and accommodative stimulus (p < 0.05), with significant interactions between some of these variables. Overall, emmetropes had smaller lags of accommodation than myopes with respective means ± standard errors of 0.31 ± 0.08 D and 0.61 ± 0.06 D (p = 0.003). Lags were largest for the Grand Seiko and Zernike defocus, intermediate for NS and VSMTF, and least for Seidel defocus.ConclusionsThe mean lag of accommodation in emmetropes is approximately equal to the previously reported depth of focus. Myopes had larger (double) lags than emmetropes. Differences between methods and instruments could be as great as 0.50 D, and this must be considered when comparing studies and outcomes. Accommodative lag increased with the accommodation stimulus, but only for methods using a fixed small pupil diameter.

Compact Models of Presbyopia Accommodative Errors for Wearable Adaptive-Optics Vision Correction Devices

Subjective accommodation refractive error models are essential for implementing adaptive vision correction devices that utilize varifocal optics. This article describes compact empirical models of subjective accommodative refractive errors in subjects with advanced presbyopia. The models are based on measurements of subjective refractive errors from fifteen presbyopes over the age of 45 using commercially available focus-tunable eyeglasses under three different illumination conditions over a 3.08D accommodation stimulus range. The resulting average residual root-mean-squared (RMS) error values for the best fitting 8-parameter model was 0.25D compared to an average RMS error of 0.4D for the conventional DDF and HHG models. The RMS error for the best-fitting model is below the average refractive error of the human eye.

Safety and efficacy of 0.02% and 0.01% atropine on controlling myopia progression: a 2-year clinical trial

Four hundred myopic children randomly received atropine 0.02% (n = 138) or 0.01% (n = 142) in both eyes once-nightly or only wore single-vision spectacles (control group) (n = 120) for 2 years. Spherical equivalent refractive error (SER), axial length (AL), pupil diameter (PD), and amplitude of accommodation (AMP) were measured every 4 months. After 2 years, the SER changes were − 0.80 (0.52) D, − 0.93 (0.59) D and − 1.33 (0.72) D and the AL changes were 0.62 (0.29) mm, 0.72 (0.31) mm and 0.88 (0.35) mm in the 0.02% and 0.01% atropine groups and control group, respectively. There were significant differences between changes in SER and AL in the three groups (all P < 0.001). The changes in SER and AL in the 2nd year were similar to the changes in the 1st year in the three groups (all P > 0.05). From baseline to 2 years, the overall decrease in AMP and increase in PD were not significantly different in the two atropine groups, whereas the AMP and PD in the control group remained stable (all P > 0.05). 0.02% atropine had a better effect on myopia control than 0.01% atropine, and its effects on PD and AMP were similar to 0.01% atropine. 0.02% or 0.01% atropine controlled myopia progression and AL elongation synchronously and had similar effects on myopia control each year.

Higher order aberrations and retinal image quality during short-term accommodation in children

Changes in higher order aberrations (HOA’s) and retinal image quality during accommodation have not previously been examined in children. This study measured ocular HOA’s in ninety non-myopic, school-aged children during short-term accommodation tasks at 0, 3, 6, and 9 D demands presented via a Badal optometer mounted to a Hartmann-Shack wavefront aberrometer (COAS-HD, Wavefront Sciences). Eighty-four participants who exhibited active accommodation were included in the analyses. An eighth order Zernike polynomial was fit across a 2.3 mm, 4 mm, and natural pupil diameter to evaluate changes in refractive power vectors (M, J180, and J45), accommodation errors (lags and leads), HOA root mean square (RMS) variables, individual Zernike coefficients, and the visual Strehl ratio based on the optical transfer function (VSOTF). All HOA RMS variables changed significantly with accommodation, with the greatest change observed for the 9 D demand. Of the individual Zernike coefficients, primary (C40) and secondary spherical aberration (C60) exhibited the greatest magnitude of change, becoming negative and positive with increasing accommodation, respectively. The VSOTF changed significantly with greater accommodation for both the 4 mm and natural pupil size, becoming significantly worse for the 9 D demand. HOA’s increase and retinal image quality decreases significantly during higher levels of accommodation in children, similar to adults. These findings provide a greater understanding of the optical properties of children’s eyes and insights into possible mechanisms for the association between accommodation, near work, and refractive error development.

Distribution of near Point of Convergence, near Point of Accommodation, Accommodative Facility and Refractive Errors in a Rural Population Living in Northern Iran

ABSTRACT Purpose: To evaluate near point of convergence (NPC), near point of accommodation (NPA), and accommodative facility (AF) in order to determine their normative data in a rural population. Methods: The target population for this population-based, cross-sectional study was people living in rural areas. Each subject underwent extensive optometric and ophthalmic examinations, including the measurement of visual acuity, refraction, NPA, NPC, and AF. Results: The data of 1113 individuals was analyzed of whom 58.8% (n = 576) were women. The mean age of the participants was 15.26 ± 7.38 years (range: 6–30 years). The mean spherical equivalent of the subjects was 0.16 ± 0.63 D. The prevalence of myopia, hyperopia and astigmatism was 16.28% (13.97–18.58), 5.97% (4.49–7.44), 11.93% (9.91–13.95) in this study, respectively The mean and 95% confidence interval of NPC, NPA, and binocular accommodative facility (BAF) was 6.99 cm (6.84–7.15), 9.91 cm (9.71–10.11), and 9.84 cpm (9.63–10.06), respectively. A significant correlation was found between age and the parameters such that all evaluated parameters worsened significantly with age (P < .001). Conclusion: The results of the present study showed the normal ranges of NPA, NPC, and BAF in a 6–30 year-old population living in rural areas of northern Iran. These parameters changed significantly with age.

Lags and leads of accommodation in humans: Fact or fiction?

The focusing response of the human eye — accommodation — exhibits errors known as lags and leads. Lags occur when the stimulus is near and the eye appears to focus farther than the stimulus. Leads occur with far stimuli where the eye appears to focus nearer than the stimulus. We used objective and subjective measures simultaneously to determine where the eye is best focused. The objective measures were made with a wavefront sensor and an autorefractor, both of which analyze light reflected from the retina. These measures exhibited typical accommodative errors, mostly lags. The subjective measure was visual acuity, which of course depends not only on the eye's optics but also on photoreception and neural processing of the retinal image. The subjective measure revealed much smaller errors. Acuity was maximized at or very close to the distance of the accommodative stimulus. Thus, accommodation is accurate in terms of maximizing visual performance.

Accommodation and refractive error of children with congenital Zika syndrome

Accommodation and refractive error of children with congenital Zika syndrome

Bifocals reduce strabismus in children with Down syndrome: Evidence from a randomized controlled trial.

AbstarctPurposeChildren with Down syndrome (DS) more often have strabismus, refractive errors, accommodative lags and reduced visual acuity (VA) than typically developing children. In this study, we compare the effects of bifocal glasses with those of unifocal glasses in children with DS. Changes in angle of strabismus, accommodation and refractive error were analysed in this paper.MethodsIn a multicentre randomized controlled trial, 119 children with DS, aged 2–16, were randomly allocated for bifocal or unifocal glasses (with full correction of refractive error in cycloplegia). The 15 centres, all in the Netherlands, followed the participants for 1 year. Changes in refractive error, accommodative accuracy, strabismus, binocularity and stereopsis were compared across 4 subsequent visits.ResultsRefractive errors and accommodative errors showed no significant change throughout the course of our study in either intervention group. The manifest angle of strabismus, however, reduced significantly in the bifocal group. This improvement was observed shortly after the children received their new correction (~6 weeks) (linear regression: t = 3.652, p < 0.001) and remained present in the final measurements after 1 year (linear regression: t = 3.604, p < 0.001). The percentage of children with positive binocularity and stereo tests showed no significant differences between the groups.ConclusionBifocals with full correction of refractive error reduce the manifest angle of strabismus within a few weeks. No effects on accommodation, refractive error, stereopsis and binocularity occurred over the course of 1 year.

Corneal Stromal Opacities Accompanied by Hyperopia and Irregular Astigmatism: Two-Step Technology of the Clinical Rehabilitation

Purpose: to identify risk factors for the development of asthenopic syndrome (AS) in patients with moderate to high myopia after keratorefractive surgery (KRS).Materials and methods. 122 patients (244 eyes) with medium and high myopia underwent a standard pre-operative examination of patients before KRS. The special methods of examinations were the study of reserves of relative accommodation (RRA) and the volume of absolute accommodation (VAA), and the accomodomography; the vision characteristics was determined on a four-point color test by E.B. Belostotsky, S.Y. Friedman at distances of 5.00 and 0.33 m, fusional reserves — with synoptophor. Patients survey was held with CISS questionnaire to detect the presence of AS.Results: There were no complications after KRS in all cases. Uncorrected visual acuity was the same or higher than maximal corrected before surgery in 1 week after KRS. Patents were divided into 2 groups according to results of CISS survey: 88% — without AS, 12% — with signs of AS. Retrospective analysis of pre-operative data of the patients with AS has shown that a combination of an absence of binocular vision with a pronounced decrease in fusion reserves, reserves of relative accommodation and volume of absolute accommodation is prognostically unfavorable factors in patients with myopia.Conclusion: All patients with moderate and high myopia have the refractive errors, there is no binocular vision in 12.3% patients. More significant errors of accommodation and binocular function were registered in patients with postoperative AS vs. patients without AS. Low fusion reserves and absence of binocular vision don’t allow to adopt for KRS results. This group of patients should be separated for pre-operative functional preparation.

Detection of the Risk Factors for Postoperative Asthenopia in Patients with Refractive Disorders

Purpose: to identify risk factors for the development of asthenopic syndrome (AS) in patients with moderate to high myopia after keratorefractive surgery (KRS).Materials and methods. 122 patients (244 eyes) with medium and high myopia underwent a standard pre-operative examination of patients before KRS. The special methods of examinations were the study of reserves of relative accommodation (RRA) and the volume of absolute accommodation (VAA), and the accomodomography; the vision characteristics was determined on a four-point color test by E.B. Belostotsky, S.Y. Friedman. at distances of 5.00 and 0.33 m, fusional reserves — with synoptophor. Patients survey was held with CISS questionnaire to detect the presence of AS.Results: There were no complications after KRS in all cases. Uncorrected visual acuity was the same or higher than maximal corrected before surgery in 1 week after KRS. Patents were divided into 2 groups according to results of CISS survey: 88% — without AS, 12% — with signs of AS. Retrospective analysis of pre-operative data of the patients with AS has shown that a combination of an absence of binocular vision with a pronounced decrease in fusion reserves, reserves of relative accommodation and volume of absolute accommodation is prognostically unfavorable factors in patients with myopia.Conclusion: All patients with moderate and high myopia have the refractive errors, there is no binocular vision in 12.3% patients. More significant errors of accommodation and binocular function were registered in patients with postoperative AS vs. patients without AS. Low fusion reserves and absence of binocular vision don’t allow to adopt for KRS results. This group of patients should be separated for pre-operative functional preparation.

Lag of accommodation does not predict changes in eye growth in chickens

Emmetropization is controlled by the defocus in the retinal image. It is a classical problem how changes in focus, introduced by accommodation, are taken into account. We have quantified accommodation errors in chickens wearing negative lenses to find out whether they can predict subsequent eye growth. Two groups of chicks, aged 10 to 13 days, wore lenses (−7D) monocularly for 4–7 days. Fellow eyes remained untreated. Vitreous chamber depth (VCD) was measured in alert hand-held chickens with high resolution, using the Lenstar LS 900 (Haag-Streit, Koeniz, Switzerland). Non-cycloplegic refractive state was measured by automated infrared photoretinoscopy with and without the lenses in place. In group 1 (n = 6), measurements were done 5 times a day to obtain detailed VCD growth curves. In group 2 (n = 10), measurements were only taken twice, at 9 am and 4 pm, to reduce the risk of recovery from induced myopia due to the frequent removal of the lenses. As expected from the negative power of the lenses, refractions measured through the lenses were more hyperopic although not as much as predicted by the lens powers, indicating that chickens partially refocused their eyes by accommodation. Among different animals, accommodation errors varied from 1.1 ± 0.9 to 3.6 ± 1.1D (group 1, mean ± 1 standard deviation) and 0.22 ± 1.25 to 1.72 ± 1.23D (group 2). No correlations were found between the magnitude of the accommodation errors in individual animals and subsequent changes in VCD. With negative lenses, VCD grew both during day and night while fellow eyes grew only during the day but shrank during the night. In conclusion, accommodation errors did not predict future eye growth. This raises the question as to why brief periods of clear vision, when lenses are taken off, have a strong inhibitory effect on myopia development while periods of clear vision due to accommodation have apparently no effect. A possible explanation is that, in addition to retina-driven control of eye growth, there is a second neural pathway for the control of eye growth that carries the signal of accommodation – although it is striking that no neuronal and structural correlate has been identified to date.

Accommodative Behavior of Young Eyes Wearing Multifocal Contact Lenses.

The effectiveness of multifocal contact lenses (MFCLs) at slowing myopia progression may hinge on the accommodative behavior of young eyes fit with these presbyopic style lenses. Can they remove hyperopic defocus? Convergence accommodation as well as pupil size and the zonal geometry are likely to contribute to the final accommodative responses. The aim of this study was to examine the accommodation behavior of young adult eyes wearing MFCLs and the effectiveness of these MFCLs at removing foveal hyperopic defocus when viewing near targets binocularly. Using a high-resolution Shack-Hartmann aberrometer, accommodation and pupil behavior of eight young adults (27.25 ± 2.05 years) were measured while subjects fixated a 20/40 character positioned between 2 m and 20 cm (0.50 to 5.00 diopters [D]) in 0.25-D steps. Refractive states were measured while viewing binocularly and monocularly with single-vision and both center-distance and center-near +2.00 D add MFCLs. Refractive state was defined using three criteria: the dioptric power that would (1) minimize the root mean square wavefront error, (2) focus the pupil center, and (3) provide the peak image quality. Refractive state pupil maps reveal the complex optics that exist in eyes wearing MFCLs. Reduced accommodative gain beyond the far point of the near add revealed that young subjects used the added plus power to help focus near targets. During accommodation to stimuli closer than the far point generated by the add power, a midperipheral region of the pupil was approximately focused, resulting in the smallest accommodative errors for the minimum root mean square-defined measures of refractive state. Paraxial images were always hyperopically or myopically defocused in eyes viewing binocularly with center-distance or center-near MFCLs, respectively. Because of zone geometry in the concentric MFCLs tested, the highly aberrated transition zone between the distance and near optics contributed a significant proportion and sometimes the majority of light to the resulting images. Young eyes fit with MFCLs containing significant transition zones accommodated to focus pupil regions between the near and distance optics, which resulted in less than optimal retinal image quality and myopic or hyperopic defocus in either the pupil center or pupil margins.

Longitudinal Evaluation of Accommodation During Treatment for Unilateral Amblyopia.

PurposeRetinal image quality is dependent on accommodative performance. This longitudinal observational study of children with unilateral amblyopia evaluated the accommodative performance of the amblyopic eye during treatment.MethodsTwenty-six participants with unilateral amblyopia and 10 participants with typical vision aged 3 to 10 years participated. Accommodative response was measured using modified Nott retinoscopy in monocular and binocular viewing conditions for target distances of 50, 33, and 25 cm, at enrollment and each follow-up visit.ResultsParticipants with amblyopia accommodated less accurately when viewing with their amblyopic eye in monocular than in binocular conditions. Over the course of amblyopia treatment, accommodative performance improved with amblyopic eye visual acuity (VA) improvement, although this was not consistent across individual participants. A linear mixed model showed that accommodative error worsened with increasing depth of amblyopia for monocular viewing with the amblyopic eye (0.14 diopter [D] per line of acuity loss, P = 0.001), with an interaction between VA and stimulus demand (0.09 D of additional lag per diopter of stimulus, per line of acuity loss, P < 0.001). Participant age, patching duration, length of time in the study, history of strabismus, and stereoacuity were not significant predictors of accommodative performance.ConclusionsOverall, poor monocular accommodative performance of the amblyopic eye was associated with worse amblyopia and improved simultaneously with VA improvement, although there was variability across the study cohort. Further research is needed to determine the causal relationship between amblyopic eye VA and accommodation and its impact on amblyopia treatment.

Accommodative stimulus-response curves to low-pass filtered natural images.

To assess how the monocular steady-state accommodative stimulus-response curve is modified when viewing low-pass filtered natural images. Eighteen adult subjects participated in the study. The accommodative stimulus-response curve was objectively assessed by means of a Hartmann-Shack wavefront sensor. Measurements were taken at different accommodative demands. Target images were low-pass filtered versions of a natural image that were obtained applying different digital spatial filters that limited the spatial frequency content of the natural image. Cutoff spatial frequencies were set at 30, 21, and 15 cycles per degree (cy/deg). Mean data obtained for each target were fitted to linear models. For the low-pass filtered natural image with a cutoff spatial frequency at 30 cy/deg, the slope for the averaged stimulus-response curve was 0.614, while the slopes obtained for the other two low-pass filtered images corresponding to cutoff frequencies at 21 and 15 cy/deg were 0.613 and 0.619, respectively (p < 0.01). The determination coefficient was R2 ≥ 0.988 for all targets. An ANCOVA analysis revealed that these slopes were not significantly different from each other (p = 0.82). Additionally, accommodative error indexes were obtained to measure both the discrepancy between the regression lines and the ideal lines and the degree of correlation between the stimulus and the response. Our study reveals that the low and middle spatial frequencies (< 15 cy/deg) are the most important to guide to the needed levels the accommodative response to natural images.