There is an urgent need for high-quality talents with ideological and moral character for the development of higher education and the cultivation of English majors who meet the requirements of the times. The course reform in English majors from the ideological and political perspective is an important way to improve the comprehensive quality and moral values of students, which helps to cultivate English talents with social responsibility and innovative abilities. This paper analyzes the problems in the current courses through literature review and field research, such as the lack of ideological and political perspective and low interest of students in ideological and political content. Based on these issues, taking the course “Comprehensive English” as an example, various teaching stages were practiced from the aspects of learning objectives, learning content, learning situation, implementation ideas, implementation effects, and teaching evaluation. Additionally, some suggestions are proposed, such as integrating ideological and political content into the entire process of teaching. The teaching staff needs to possess high-level English teaching ability and ideological and political perspective, standardize the evaluation system, and integrate epistemology into the evaluation process of ideological and political education, in order to promote in-depth research and exploration of ideological and political education of English majors.