60Co Γ-rays Research Articles

Study of a gel dosimeter based on Ag nanoparticles for applications in radiation therapy with synchrotron X-rays at ultrahigh dose rate compared to 60Co γ-rays

A silver nitrate (AgNO3) gel was developed and evaluated as a dosimeter for synchrotron X-ray-based studies in microbeam radiation therapy (MRT) and FLASH radiation therapy. The gel was irradiated at the European Synchrotron Radiation Facility (ID17 Biomedical beamline) with a continuous X-ray spectrum in the 50–600 keV range and a dose rate of 11.6 kGy/s. The spectrophotometric response after irradiation at this beamline was compared with the response at a conventional 60Co γ-ray source providing a dose rate of 0.27 Gy/s. Ag + ions in the gel dosimeter undergo reduction to Ago nanoparticles, as detected at 450 nm, which is a surface plasmon resonance band. The intensity of this band increased linearly with increasing absorbed dose up to 100 Gy, and improved with the addition of glycerol. The gel dosimeter exhibited the lowest detectable dose (LDD) of 75.9% lower and a dose deposition of 76% higher for ID17 beamline irradiation than for 60Co irradiation. The theoretical relative response HQ,Qo for the gel irradiated at the synchrotron was 1.70, which is in close agreement with the experimental relative response FQ,Qo = 1.76. These results confirm the dose enhancement in the gel irradiated with orthovoltage X-rays. The good properties of the silver nitrate gel, together with its increased sensitivity to orthovoltage X-ray irradiation and modest overall uncertainty of 5.8% (2σ), confirm that the gel is a valid dosimeter for measurements at ultrahigh dose rates for synchrotron radiotherapy. The dosimeter is also a promising candidate for dose enhancement factor measurements in nanoparticle-based radiotherapy techniques.

Study on the protective effect of flavonoids extracted from Jatropha curcas leaves against radiation damage in mice

The primary objective of this study was to evaluate the radioprotective effects of Flavonoids Extracted from Jatropha curcas Leaves (FEL) and to elucidate the underlying protective mechanisms against radiation damage. Six monomers of the FEL were analyzed using Ultra Performance Liquid Chromatography (UPLC). The results indicate that FEL increases the survival rate of mice and promotes the recovery of organs damaged by 60Co γ-rays to their normal appearance, through mechanisms that include the enhancement of immune and hematopoietic functions in vivo. In vitro studies suggest that the molecular mechanism by which FEL mitigates radiation damage involves the reduction of DNA damage and mutations. These findings indicate that FEL could be effective in alleviating radiation-induced injuries.

Study on the preservation effect of 60Co-γ ray irradiation on potatoes

To evaluate the effect of irradiation on the preservation of potatoes, fresh potatoes were selected as the irradiation objects, and irradiated with 60Co-γ radiation source for 0, 100, 200, 500 and 1000 Gy, respectively. During the irradiation, the well-packaged Y1.79Bi0.01Eu0.2MgTiO6 novel thermoluminescence dosimeter material was placed together with the potatoes at the same position. Then, the potatoes were stored in the same temperature and humidity environment, and the quality changes of the potatoes were observed. The Y1.79Bi0.01Eu0.2MgTiO6 material had good performance indicators, and was used to measure the irradiation dose of the potatoes. The experiment showed that irradiation could appropriately extend the storage time of potatoes, and gamma irradiation of about 1000 Gy could achieve the best preservation effect. The main pathogenic fungi that cause dry rot of potatoes were Fusarium solani and Fusarium oxysporum, and the appropriate dose of 60Co-γ irradiation could effectively inhibit the spread and growth of these fungi.

Fabrication of highly thermally conductive and irradiation resistant UHMWPE-based composites for nuclear shielding applications

With the advancement of nuclear energy, the safety of both humans and the surrounding environment necessitates the adoption of effective nuclear radiation shielding materials. Polymer-based shielding materials have garnered attention due to their lightweightness and ease of moldability. However, they normally possess low thermal conductivity (λ) and easy deformation at high temperatures, which potentially cause catastrophic disasters during service if they are mechanically failed due to heat accumulation. To address the above concerns, highly thermally conductive and irradiation resistant ultra-high molecular weight polyethylene (UHMWPE)-based composites were fabricated. Planar fillers such as boron nitride (BN) and graphite (Gt) along with lead (Pb) powders were employed to construct a densely packed filler network for improving the λ and mechanical properties of UHMWPE-based composites. The λ was increased from 3.81 to 6.20 W/mK when 20 wt% Pb (2.88 vol%) was added to BN30/Gt20 (i.e., UHMWPE composite with 30 wt% BN and 20 wt% Gt), representing an increase of 62.73 %. Moreover, the λ of Pb80 was increased from 0.87 to 3.29 W/mK by merely adding 5 wt% (9.99 vol%) Gt, representing a remarkable increase of 278.16 %. GEANT4 simulation results indicated that BN30/Gt20/Pb20 exhibited excellent neutron shielding performance. Samples which were irradiated using 60Co γ-rays at a total dosage of 1.15×105 Gy exhibited enhanced mechanical performance, which indicated excellent irradiation resistance of UHMWPE-based composites. Therefore, a facile method was proposed to prepare multi-functional UHMWPE-based composites that demonstrate promising application in nuclear sectors.

Research on the Stability and Response of Food Packaging Polystyrene Resin Materials to γ-ray Irradiation.

Radiation stability of food packaging materials is the key to ensuring food quality. In this study, 60Co γ-ray was selected to investigate the radiation resistance of food packaging polystyrene (PS) resin material, although the FTIR analysis showed that the intensity of several peaks decreased slightly. The gel permeation chromatography (GPC) results displayed that the value of peak molecular weight (Mp) of PS went from 2.68 × 105 g/mol down to 2.22 × 105 g/mol. Moreover, the residual mass (Res) of PS increased from 7.208 to 30.23%, indicating that the tendency of coking of PS was stronger after irradiation. In addition, the peak intensities of the three main pyrolysis products -CH2-, CH4, and CH2=CH2 increased by more than 30% compared to unirradiated PS, and a large number of them were detected in the whole pyrolysis process. Moreover, mechanical property analysis finds that both breaking strength and elongation data increased before irradiation dose of 50 kGy, then, decreased sharply with further increase of irradiation dose. The theoretical bond order analysis confirmed that the tertiary carbon bond attaching the benzene ring had the lowest bond energy. This study can give helpful guidance when using PS for food packing materials.

Photocatalytic CO2 reduction and destruction of rhodamine B on Bi0/BiOCl with tunable oxygen vacancies induced by 60 CO γ-rays irradiation

In this work, Bi0/OVs-BiOCl photocatalysts were in-situ constructed by irradiating BiOCl with 60Co γ-rays. The powerful penetrating ability of γ-rays induce the Bi-O bonds in BiOCl to break, thereby leading to the deoxygenation (OVs) and the formation of metal Bi0. The presence of Bi0 and OVs endows the photocatalysts with enhanced separation of photogenerated charges and enriched active sites. Under the excitation of simulated sunlight, the BOC-5 sample with an irradiation dosage of 5 KGy demonstrates the best photocatalytic performance, and the yield of CO on the sample is 2.19 μmol·g−1·h−1, which is 2.27 times higher than that on the reference sample. In-situ diffuse reflectance Fourier transform infrared spectroscopy (DRIFTS) reveals the formation of intermediates during the conversion of CO2 to CO. Under irradiation of a 300 W xenon lamp, the degradation rate of rhodamine B (RhB) on the BOC-5 sample is 0.05843 min−1, which is 3.42 times of that on the reference sample (0.01708 min−1). The main active species in the degradation process were explored using electron paramagnetic resonance (EPR) and free radical capture experiments at room temperature. This study provides a novel strategy for the preparation of BiOCl-based photocatalysts with high photocatalytic activity through 60Co γ-rays irradiation.

Research on the degradation of resolution in cameras based on CMOS image sensor under γ- and X-rays irradiation

Remote control engineering in industry usually requires cameras to assist target identification and detection, but the cameras working in nuclear environments face the threat of radiation-induced degradation. Both γ- and X-rays in nuclear environments will cause ionizing radiation damage, but the difference in degradation of camera’s performance induced by ionizing radiation damage with equivalent total ionizing dose (TID) of these two rays is unclear, which is crucial for the evaluation of camera performance in a nuclear radiation environment. In order to figure out the degradation of CMOS cameras by ionization radiation damage under different rays, this study conducted irradiation experiments on CMOS image sensors under X-ray with 10 keV and 60Co-γ ray with 1.25 MeV, respectively, and then tested and calculated the resolution of camera based on this CMOS image sensor. After comparing and analyzing the results, it was found that the dark current and full well capacity of the CIS, as well as the resolution of the camera, were more severely degraded after X-ray irradiation. Further analysis found that the interface dose enhancement effect of X-ray, as well as the generation of high-density oxide trapped charges in the gate oxide, aggravated the degradation of full well capacity on the CIS after X-ray irradiation, resulting in more severe degradation in the resolution of the CMOS camera. This study provides theoretical basis for the safety and reliability evaluation of cameras in strong nuclear radiation environments.

Selection and characterization a new strain (PS-M4) of Pyropia suborbiculata with fast growth based on 60Co-γ ray irradiation

Selection and characterization a new strain (PS-M4) of Pyropia suborbiculata with fast growth based on 60Co-γ ray irradiation

Beam quality conversion factor of BeO-OSLD for high-energy photon beams

Optically stimulated luminescence (OSL) dosimeters are used in radiotherapy. The beam quality conversion factor (kQ) of dosimeters is essential for correcting energy dependence. However, the kQ of an OSL dosimeter using BeO (BeO-OSLD) has not yet been reported for high-energy photon beams. In this study, the kQ of BeO-OSLD was investigated for high-energy photon beams using experiments and Monte Carlo calculations. In the experiments, kQ was evaluated as the ratio of calibration coefficients determined using high-energy photon beams and 60Co γ-rays. Ten OSL dosimeters were used to reduce the statistical uncertainty of the determined kQ values, and the same dosimeters were repeatedly used to obtain the data set of high-energy photon beams and 60Co γ-rays. Pre-irradiation with 10 Gy and bleaching were performed on fresh dosimeters before dosimetry to reduce the dependence of the detector response on the accumulated dose. In Monte Carlo calculations, both the absorbed dose to water and that of the BeO dosimeter for high-energy photon beams and 60Co γ-rays were calculated, and then kQ was determined using the ratio of these values. The determined kQ values in high-energy photon beam were 0.998 ± 0.011 and 1.021 ± 0.005 for the experiment and the calculation, respectively. These results showed that the variation in kQ for 6–25 MV was negligible in practical dosimetry. This result indicates that BeO can be used to evaluate doses for different beam qualities without correcting for energy dependence.

Single-dose Administration of Recombinant Human Thrombopoietin Enhances Survival and Hematopoietic Reconstruction in Canines Irradiated with 3 Gy Gamma Radiation.

We conducted this study to investigate the radioprotective effects of recombinant human thrombopoietin (rhTPO) on beagle dogs irradiated with 3.0 Gy 60Co gamma rays. Fifteen healthy adult beagles were randomly assigned to a control group with alleviating care, and 5 and 10 μg/kg rhTPO treatment group. All animals received total-body irradiation using 60Co γ-ray source at a dose of 3.0 Gy (dose rate was 69.1 cGy/min). The treatment group received intramuscular injection of rhTPO 5 and 10 μg/kg at 2 h postirradiation, and the control group was administrated the same volume of normal saline. The survival rate, clinical signs, peripheral hemogram, serum biochemistry, and histopathological examination of animals in each group were assessed. Single administration of 10 μg/kg rhTPO at 2 h postirradiation promoted the recovery of multilineage hematopoiesis and improved the survival rate of beagles irradiated with 3 Gy 60Co γ rays. The administration of 10 μg/kg rhTPO alleviated fever and bleeding, reduced the requirement for supportive care, and may have mitigated multiple organ damage.

Design and preparation of WBX/Al composites for nuclear radiation protection

As the utilization of nuclear energy continues to expand, there is a growing focus on the development of lightweight and efficient nuclear shielding composites. In this paper, novel WBX/Al (x = 1, 2, 4) composites were designed based on shielding performance. The effects of reinforcement type, volume fraction, and material thickness on the 60Co and 137Cs γ-rays, fast and thermal neutron shielding performances were simulated. The results show that WB/Al composites offer better development potential compared to WB2/Al or WB4/Al composites. Additionally, a predictive model for the γ-ray shielding effectiveness of WB/Al composites, based on the areal density of tungsten, was proposed. The fabrication process involved mechanical ball milling and spark plasma sintering to fabricate 30 vol% WB/Al composites, with optimization of ball milling time, sintering temperature, and holding time. As a result, a novel nuclear radiation protection composite with uniform composition, a relative density of 97 %, and flexural strength of 527 MPa was acquired.

Synergistic Radiation Effects in PPD CMOS Image Sensors Induced by Neutron Displacement Damage and Gamma Ionization Damage.

The synergistic effects on the 0.18 µm PPD CISs induced by neutron displacement damage and gamma ionization damage are investigated. The typical characterizations of the CISs induced by the neutron displacement damage and gamma ionization damage are presented separately. The CISs are irradiated by reactor neutron beams up to 1 × 1011 n/cm2 (1 MeV neutron equivalent fluence) and 60Co γ-rays up to the total ionizing dose level of 200 krad(Si) with different sequential order. The experimental results show that the mean dark signal increase in the CISs induced by reactor neutron radiation has not been influenced by previous 60Co γ-ray radiation. However, the mean dark signal increase in the CISs induced by 60Co γ-ray radiation has been remarkably influenced by previous reactor neutron radiation. The synergistic effects on the PPD CISs are discussed by combining the experimental results and the TCAD simulation results of radiation damage.

Screening radiation-differentially expressed circular RNAs and establishing dose classification models in the human lymphoblastoid cell line AHH-1

Purpose In the event of a large-scale radiological accident, rapid and high-throughput biodosimetry is the most vital basis in medical resource allocation for the prompt treatment of victims. However, the current biodosimeter is yet to be rapid and high-throughput. Studies have shown that ionizing radiation modulates expressions of circular RNAs (circRNAs) in healthy human cell lines and tumor tissue. circRNA expressions can be quantified rapidly and high-throughput. However, whether circRNAs are suitable for early radiation dose classification remains unclear. Methods We employed transcriptome sequencing and bioinformatics analysis to screen for radiation-differentially expressed circRNAs in the human lymphoblastoid cell line AHH-1 at 4 h following exposure to 0, 2, and 5 Gy 60Co γ-rays. The dose–response relationships between differentially expressed circRNA expressions and absorbed doses were investigated using real-time polymerase chain reaction and linear regression analysis at 4 h, 24 h, and 48 h post-exposure to 0, 2, 4, 6, and 8 Gy. Six distinct dose classification models of circRNA panels were established and validated by receiver operating characteristic (ROC) curve analysis. Results A total of 11 radiation-differentially expressed circRNAs were identified and validated. Based on dose–response effects, those circRNAs changed in a dose-responsive or dose-dependent manner were combined into panels A through F at 4 h, 24 h, and 48 h post-irradiation. ROC curve analysis showed that panels A through C had the potential to effectively classify exposed and non-exposed conditions, which area under the curve (AUC) of these three panels were all 1.000, and the associate p values were .009. Panels D through F excellently distinguished between different dose groups (AUC = 0.963–1.000, p < .05). The validation assay showed that panels A through F demonstrated consistent excellence in sensitivity and specificity in dose classification. Conclusions Ionizing radiation can indeed modulate the circRNA expression profile in the human lymphoblastoid cell line AHH-1. The differentially expressed circRNAs exhibit the potential for rapid and high-throughput dose classification.

Gene Mapping of a Yellow-to-Lethal Mutation Based on Bulked-Segregant Analysis-Seq in Soybean

Plant photosynthesis is mainly dependent on leaf color, and this has an impact on yield. Mutants lacking in chlorophyll have been analyzed to gain insight into the genetic processes involved in photosynthesis, chloroplast development, and chlorophyll metabolism. A yellow-to-lethal mutant, ytl, was selected from the M6 generation of the 60Coγ ray irradiation-treated soybean cultivar Nannong 1138-2. The mutant exhibited reduced chlorophyll content, with the thylakoid structure disrupted. Segregation of the cross between Williams 82 (W82) and ytl indicated that a recessive allele controlled yellow-to-lethal traits. The bulked-segregant analysis (BSA)-Seq method performed preliminary mapping, followed by simple sequence repeat (SSR) marker validation and further mapping. The candidate gene was mapped to a 418 Kb region containing 53 genes. High-throughput sequencing and first-generation sequencing results showed a two bp deletion in the second exon of Glyma.08g106500, leading to a frameshift mutation in ytl. As a promising candidate gene, Glyma.08g106500 encoded a chloroplast-localized pentatricopeptide repeat (PPR) domain-containing protein involved in the assembly of chloroplast proteins. These results will contribute to cloning the mutant ytl gene and provide insight into the regulatory processes controlling photosynthesis and chloroplast development and growth in soybean.

Analysis of the effect of 60Co irradiation sterilization on the chemical composition of volatile organic compounds in Rhizoma Acori Tatarinowii using GC-IMS

The volatile organic compounds (VOCs) of Rhizoma Acori Tatarinowii were extracted via steam distillation and then irradiated with 60Co-γ rays, in which doses of 60Co-γ 0, 5, and 10 kGy were selected to irradiate the VOCs. Finally, gas chromatography–ion mobility spectrometry (GC-IMS) was used to compare the differences between the VOCs, and then qualitatively analyse the components and contents of each part of the VOCs The results showed that under the three irradiation doses of 60Co-γ 0, 5 and 10 kGy, the VOCs of unirradiated and 5 kGy-irradiated samples were closer, and the samples irradiated at a 10 kGy dose were quite different from the other two components, meaning that when the calamus medicinal materials were sterilised by means of 60Co irradiation, the dose of 5 kGy was closer to the original compound content of the medicinal materials.

Effect of 60Coγ ray radiation on electrical properties of SiGe HBTs at low temperatures

In this article, total ionizing dose (TID) irradiation experiments were carried out on germanium-silicon heterojunction bipolar transistors (SiGe HBTs) under different bias and temperature conditions. The electrical performance and noise characteristics of the device were characterized before and after irradiation using a semiconductor parameter analyzer and a 1/f noise test system, respectively. The variation of radiation sensitivity parameters with the TID effect and temperature of the device was obtained, and the mechanism of radiation damage degradation was also identified. Results suggest that the oxide-trap charges and interface states induced by irradiation are the main causes for SiGe HBT electrical parameters degradation. With the decreased temperature, Gummel characteristics and 1/f noise are significantly improved. It's found that oxide-trap charges and interface states generated at 93 K is less than that at 300 K. This work lays the foundation for the application of SiGe HBT in aerospace area.

Construction of Watermelon Mutant Library Based on 60Co γ-ray Irradiation and EMS Treatment for Germplasm Innovation

Watermelon is a crucial horticultural crop worldwide but its genetic base has become extremely narrow owing to long-term cultivation. Induced mutagenesis can create a range of variations with distinctive agricultural characteristics. To broaden the genetic diversity of watermelon, we established a mutagenesis library containing over 4000 M1 seeds from an inbred line ‘M08’, which was irradiated by 350 Gy of 60Co γ-rays for 3 h. The rates of germination, emergence, and survival of the M1 seeds were reduced by 5.88%, 18.66%, and 41.96%, respectively. After phenotypic screening, 20 and 10 types of morphological changes were observed in the M1 and M2 generations, with approximately 10.57% and 14.17% mutation frequencies, respectively. Six mutants with desirable horticultural alterations were selected for additional presentation, including the leaf color mutant C1-NO.1, the yellow peel mutant C1-NO.2, the pericarp thickening mutant C1-NO.3, the pericarp thinning mutant C1-NO.4, the seedless mutant C1-NO.5, and the C2-No.1 mutant with normal female flowers and malformed male flowers. Moreover, the three mutants M1-3, M2-1, and M1-5 were identified from our EMS-induced M2 library, exhibiting the fusiform fruit, the dark green peel, and the yellow leaves, respectively. Compared to the wild type (WT), the photosynthetic pigments and parameters were negatively impacted in the yellow-leaf mutant M1-5. For example, the total chlorophyll was 1.22 and 2.22 mg/g in the young and mature leaves of M1-5, respectively, which were significantly lower than those in the WT (2.58 and 2.90 mg/g, respectively). Notably, some mutagenesis phenotypes could be stably inherited, including traits such as yellow leaf color, fusiform fruit shape, and thickening and thinning pericarp. Taken together, these results indicate that these two mutant libraries serve as essential resources to discover new phenotypic germplasms, thereby facilitating the genetic breeding and functional gene exploration in watermelon.

Effects of cyclophosphamide and mitomycin C on radiation-induced transcriptional biomarkers in human lymphoblastoid cells

Purpose Ionizing radiation (IR)-induced transcriptional changes are considered a potential biodosimetry for dose evaluation and health risk monitoring of acute or chronic radiation exposure. It is crucial to understand the impact of confounding factors on the radiation-responsive gene expressions for accurate and reproducible dose assessment. This study aims to explore the potential influence of exposures to chemotherapeutic agents such as cyclophosphamide (CP) and mitomycin C (MMC) on IR-induced transcriptional biomarkers. Methods The human B lymphoblastoid cells (AHH-1) were exposed to 0, 20, 50, 100, 200 and 500 μg/ml CP or 0, 0.025, 0.05, 0.1 and 1 μg/ml MMC, respectively. The appropriate concentrations of CP and MMC were added for 1 h before irradiation with 0, 2, 4 and 6 Gy of 60Co γ-rays at a dose rate of 1 Gy/min. Cell viability was evaluated by CCK-8 assay. The gene expression responses of 18 radiation-induced transcriptional biomarkers were examined at 24 h after exposures to CP and MMC, respectively. The expression levels of five crucial DNA interstrand crosslinks (ICLs) repair genes were also evaluated. The biodosimetry models were established based on the specific radiation-responsive gene combinations. Results The baseline transcriptional levels of the 18 selected genes were slightly affected by CP treatment in the absence of IR, while the transcript responses to IR could be inhibited as the concentration of CP up to 50 μg/ml. MMC treatment up-regulated the background levels in most radiation-responsive gene expressions. Of 18 genes, only the relative mRNA expression levels of CDKN1A and BBC3 were repressed after treatment with IR and MMC in combination. The relative mRNA level of RAD51 was significantly up-regulated after exposure to CP, while the expression of FANCD2, RAD51 and BLM showed an overall increase in response to MMC treatment. After irradiation, the relative mRNA expression levels of FANCD2, BRCA2 and RAD51 exhibited dose-dependent increases in IR alone and MMC treatment groups. In addition, the biodosimetry models were established using 2-4 radiation-responsive genes based on different radiation exposure scenarios. Conclusion Our findings suggested that IR-induced gene expression changes were slightly affected after exposure to a relatively low concentration of CP and MMC. Gene expression combinations might improve the broad applicability of transcriptional biodosimetry across diverse radiation exposures.

Total ionizing dose effects of 60Co-γ ray radiation on SiC MOSFETs with different gate oxide thickness

The application of SiC power devices in the space radiation environment not only requires good resistance to Single Event Effect (SEE) but also requires certain resistance to Total Ionizing Dose (TID) and long-term reliability. Increasing the thickness of the gate oxide layer (tox) can effectively improve the ability of SiC VDMOS to resist SEE. However, it will mainly impact its resistance to TID and Gate Oxide Integrity (GOI). Therefore, this paper compares the influence of tox on the radiation resistance and long-term reliability of SiC VDMOS under the same process and irradiation conditions. The experimental results show that after being irradiated by Cobalt-60 γ-rays, the static parameters of SiC VDMOS devices degrade severely with the increase of the tox; at the same time, the thick gate oxide process will also cause more defects in the gate oxide, leading to the decrease of the gate oxide long-term reliability, but it can be significantly improved after high temperature (HT) accelerated annealing. The research results suggest that the method of increasing tox should take into account the requirements of TID resistance and long-term reliability when improving the SEE radiation resistance of SiC VDMOS. This study is based on the improvement of electrical parameters and the analysis of reliability degradation of SiC VDMOS, providing experimental data support for determining the balance point of tox.

Enhancing effects of 60Co irradiation on the extraction and activities of phenolic components in edible Citri Sarcodactylis Fructus.

In this study, the impact of 60Co-γ ray irradiation treatment on the content of active chemicals and their functions in Citri Sarcodactylis Fructus (CSF) was assessed. Scanning electron microscopy, Fourier transform infrared spectroscopy, and γ-ray diffraction revealed physical structure changes in CSF powder. According to the findings, the content of total flavonoids in the ethanol extract of CSF increased by 9.5%-21.62%, 7-hydroxycoumarin, hesperidin, 5,7-dimethoxycoumarin, and 5-methoxypsoralen increased by 5.31%-51.8%, 10.07%-99.81%, 6.6%-62.29%, and 3.03%-300%, respectively, when the irradiation dosage was raised, and the antibacterial, anti-inflammatory, antioxidant, and anticancer properties were all raised considerably. These results imply that the principal components and activity changes are proportional to the irradiation dosage. At present, the findings of this study serve as a reference for the use of irradiation technology in assisting extraction and enhancing the effects of functional foods.