AbstractIn many regions of the world with complex seismic activity, the availability of seismic stations is limited. This motivated us to develop a probabilistic method for single‐station earthquake location. Single station location methods may provide an efficient and cost‐effective way to monitor small‐magnitude seismic events over large areas of the world. This method relies on the outputs of two neural networks, which predict the initial spatial location of specific areas (convolutional) used in the prior probability and seismic phase recognition (combination of convolutional and Long Short Term Memory) used in the likelihood function. These estimates and a 3D travel time likelihood function are used in a Bayesian framework. In this model, the initial spatial location is expressed as a Multivariate Gaussian Mixture Model, and the likelihood function refines the localization using the arrival time difference between S and P waves in a 3D space. The likelihood function uses a Fast Marching Eikonal method with a 3D velocity structure. We tested this method on the Ridgecrest 2019 seismic sequence (Mw = 7.1) and on West Texas and found promising results for locating with a single station. Our approach demonstrates that using a Bayesian model with strong priors obtained through deep learning algorithms is effective. Our model can predict epicenter and depth with mean errors of 7.55 km in longitude, 13.54 km in latitude and 0.630 km in depth at the two different locations studied. This method demonstrates the effectiveness of combining deep learning for initial estimations with probabilistic 3D location refinement.