8-week Program Research Articles

The Potential of Artificial Intelligence in Predicting Post-Stroke Rehabilitation Outcomes: Statistical Analysis Considering Rivermead Motor Assessment and Activities of Daily Living Indicators and Selected Demographic Variables

Strokes are currently the third most common cause of death worldwide and the leading cause of disability in people over 50 years of age. The functioning of post-stroke patients depends primarily on well-conducted rehabilitation, both in stationary conditions and at home. The aim of this study was to evaluate the functional outcomes of patients after ischemic stroke who underwent home rehabilitation. The RMA (Rivermead Motor Assessment) and ADL (activities of daily living) scales were used for evaluation. A total of 20 patients underwent a 4-week home rehabilitation program in Cracow. In the studied group, most patients showed functional improvement after the 4-week rehabilitation period. Predictive models were created (Net1, Net2, Net3) using artificial intelligence algorithms, including regression and classification methods. The analysis results indicate that the best outcomes in predicting the RMA and ADL indicators. For Net2, the prediction accuracy for the ADL indicator was 94.4%, which is significantly higher compared to the other indicators. The RMA1-3 indicators achieved relatively low accuracy rates of 38.9–44.4%. In contrast, for Net3, the RMA1-3 indicators showed high accuracy, achieving 89.1–91.3% correct results. The conclusions of the study suggest that using a combination of the Net2 and Net3 models can contribute to optimizing the rehabilitation process, allowing therapy to be tailored to the individual needs of patients. The research proves that it is possible to predict the effect of rehabilitation by using AI. The implementation of such solutions can increase the effectiveness of post-stroke rehabilitation, particularly through the personalization of therapy and dynamic monitoring of patient progress.

Evaluating the Impact of Multimodal Prehabilitation with High Protein Oral Nutritional Supplementation (HP ONS) with Beta-Hydroxy Beta-Methylbutyrate (HMB) on Sarcopenic Surgical Patients—Interim Analysis of the HEROS Study

Background: Multimodal prehabilitation programs, which may incorporate nutritional supplementation and exercise, have been developed to combat sarcopenia in surgical patients to enhance post-operative outcomes. However, the optimal regime remains unknown. The use of beta-hydroxy beta-methylbutyrate (HMB) has beneficial effects on muscle mass and strength. However, its effect on muscle quality in the perioperative setting has yet to be established. This study aims to explore the impact of a multimodal prehabilitation program using a bundle of care that includes high-protein oral nutritional supplementation (HP ONS) with HMB and resistance exercise on muscle quality and functional outcomes in sarcopenic surgical patients. Methods: Sarcopenic adult patients undergoing elective major gastrointestinal surgeries were recruited for this pilot interventional cohort study. They were enrolled in a 2–4-week multimodal prehabilitation program comprising resistance exercise, nutritional supplementation, vitamin supplementation, comorbid optimization and smoking cessation. Participants were provided three units of HP ONS with HMB per day pre-operatively. The primary outcome was changes in intramuscular adipose tissue (IMAT) as a proxy of muscle quality, assessed using Artificial Intelligence (AI)-aided ultrasonography. Secondary outcomes include changes in anthropometric measurements and functional characteristics. Outcomes were measured before prehabilitation, after prehabilitation and 1 month post-operatively. Results: A total of 36 sarcopenic patients, with a median age of 71.5 years, were included in this study. There was an increase in the IMAT index after two weeks of prehabilitation (p = 0.032) to 1 month after surgery (p = 0.028). Among functional parameters, improvement was observed in gait speed (p = 0.01) after two weeks of prehabilitation, which returned to baseline post-operatively. The median length of hospital stay was 7 (range: 2–75) days. Conclusions: The increase in the IMAT index in a sarcopenic surgical cohort undergoing prehabilitation may be due to altered muscle metabolism in elderly sarcopenic patients. A prehabilitation regime in sarcopenic patients incorporating HP ONS with HMB and resistance exercise is feasible and is associated with increased gait speed.

The Effect Of Pylates-Based Exercıse Programs On Gırls' Quıckness And Strength

ABSTRACT To investigate the effects of Pilates-based exercise programs on girls' quickness and strength. Conducted at a private Pilates studio in Kırıkkale, the research involved 50 female students aged 9-10 years, with 25 in the experimental group and 25 in the control group. A 10-week training program included exercise sessions twice a week, focusing on basic Pilates movements, balance, and strength development. Quickness and strength levels were assessed at the beginning and end of the study using specific tests. Quickness was measured through short-distance running and reaction tests, while strength was assessed by the number of repetitions in various exercises and resistance tests. The findings indicated that Pilates-based exercise programs positively impacted the quickness and strength of the girls. Specifically, Pilates movements were particularly effective in enhancing muscle strength and developing quickness. These results suggest that Pilates exercises can effectively contribute to the physical development of children. It is recommended that educators and coaches implement Pilates-based programs for children, considering the benefits of such exercises.

Influence of puberty stage in immune-inflammatory parameters in well-trained adolescent soccer-players, following 8-weeks of pre-seasonal preparation training

Aim: The immune system can experience temporary suppression following acute or prolonged strenuous exercise, potentially increasing susceptibility to infections. Young athletes, who must balance school, training, studies, and social life, may further disrupt their immune-inflammatory responses. This study aimed to investigate the effects of an 8-week pre-season training on circulating leukocyte responses in well-trained adolescent soccer-players at different stages of puberty. Methods: Thirty-six soccer players, divided into two groups based on their biological age-under sixteen (U16) and above sixteen (A16)-underwent two rounds of assessments. These included evaluations of anthropometrics, physical fitness, and immune parameters before and after an 8-week pre-season soccer training program. Results: No significant treatment or interaction effects were found for erythrocyte sedimentation rate (ESR), platelets, total leucocyte count, immune inflammation markers (IIM), weekly rating of perceived exertion, body composition, sit-and-reach flexibility, or VO2max (P > 0.05). However, post-intervention neutrophil counts were increased, while lymphocyte counts decreased, and IIM levels rose in both groups (P < 0.05). Neuromuscular explosiveness and strength endurance were significantly higher in the A16 group compared to the U16 group (P < 0.05). Body fat was reduced, and all physical fitness parameters improved in both groups over time (P < 0.05). Conclusions: The 8-week soccer-specific training program did not lead to different effects on immune-inflammatory parameters between youth soccer players at different stages of puberty. However, training adaptations, including improvements in physical fitness, were observed in both groups. This suggests that when the same training load (frequency, duration, intensity) is applied to adolescents at different stages of puberty, immune-inflammatory responses are not significantly influenced by age, but physical fitness improves regardless of puberty stage. A key limitation of this study is the lack analysis of lymphocyte subpopulations, which could provide a deeper understanding of the cellular effects of training on immune function.

Effects of 10 Weeks of Walking With Mobile Step-Tracking Apps on Body Composition, Fitness, and Psychological State in Adolescents Who Are Overweight and Obese: Randomized Controlled Trial.

In recent decades, physical activity intervention programs have been developed to reduce overweight and obesity in adolescents. However, this population is considered hard to reach in physical activity programs due to lack of adherence and poor results. Interventions with mobile phones in the adolescent population with normal weight have shown benefits, so this line of research may provide benefits in adolescents with overweight or obesity, although it has not yet been explored in the scientific literature. This study aims to determine the changes produced by a 10-week intervention promoted during school lessons on physical education using step tracker mobile apps in out-of-school hours on physical activity, adherence to the Mediterranean diet, body composition, and the physical condition of adolescents who are overweight and obese, and to analyze the changes achieved by the 10-week intervention on the psychological state of adolescents who are overweight and obese. The study was based on a randomized controlled trial with an initial sample of 50 adolescents aged between 12 and 16 years (from the first to the fourth years of compulsory secondary education), whose body composition, physical activity level, physical condition, and psychological state were measured. Participants were divided into an experimental group (EG) and a control group (CG), where the EG performed a series of walking steps with a mobile app in their free time outside physical education classes. Adolescents in the CG continued to perform their physical activities as normal but did not use any mobile apps. Inclusion in the EG and CG was randomized, and the researchers were blinded. An increase was found in the EG in corrected arm girth (mean difference -0.46; P=.05), curl-up repetitions (mean difference -6.35; P=.02) and push-up repetitions (mean difference -2.27; P=.04) after the intervention. In the CG, there was a significant increase in hip girth (mean difference -1.37; P=.05), corrected thigh girth (mean difference -1.28; P=.04), and muscle mass (mean difference -0.87; P=.04), as well as a significant decrease in competence (mean difference 3.08; P=.03). The covariates gender and age showed an effect on corrected arm girth (gender: P=.04), curl-up repetitions (gender: P=.04) and push-up repetitions (gender: P=.04) in the EG; while in the CG it affected corrected thigh girth (gender: P=.04), adherence to the Mediterranean diet (gender: P=.04 and age: P=.047) competence (gender: P=.04 and age: P=.04) and relatedness (gender: P=.05 and age: P=.04). No significant differences were found when comparing changes in the CG and EG. A 10-week program of mobile app use by adolescents who are overweight and obese for physical activity outside of school hours does not appear effective in producing improvements in body composition, physical fitness, or adequate psychological state as it does not appear to significantly increase physical activity. ClinicalTrials.gov NCT06089876; http://clinicaltrials.gov/ct2/show/NCT06089876.

Development and Evaluation of a Strengths-Focused Peer-Led Support Program for Young University Mothers

The increasing enrollment of student parents, particularly mothers, in higher education highlights the crucial need for timely support. Compared to their non-parent peers, student mothers are more likely to encounter financial, logistical, and social barriers. In this study, we evaluated the feasibility and effectiveness of a strengths-focused, peer-led support program for young university mothers (YUM). YUM adapted an evidence-based life skills program previously designed for adolescent mothers. Seventeen mothers ( Mage = 24.59; SDage = 4.65) participated in the 7-week YUM program, and 17 mothers ( Mage = 24.12; SDage = 3.10) were in the control group. Following the intervention, YUM participants demonstrated significant decreases in stress and depression, significant increases in career and academic exploration, and satisfaction with social support compared to the control group. YUM participants also reported an increased sense of campus connectedness over time, although the change was not significantly different between the two groups. In their parenting self-efficacy, the two groups demonstrated no significant differences in the change over time. The qualitative findings from exit interviews indicated high levels of satisfaction and engagement among all YUM participants, suggesting that the program was well received and feasible. YUM participants saw the group as an emotional safe haven and appreciated the peer-led structure. Despite facing multiple challenges as college-going mothers, they expressed a desire for continued skill application and ongoing support on college campuses. The study’s strengths, limitations, and implications for pedagogical and counseling practices as well as for future research are further discussed.

Evaluating the effect of a virtual reality digital therapeutic on maternal stress among expectant and postpartum Black and Latina mothers: a protocol paper

BackgroundMaternal mental health is vital to overall well-being, particularly among expectant and postpartum Black and Latina women who experience higher stress levels and mental health challenges. Traditional healthcare systems often fail to meet these needs, underscoring the need for innovative and accessible interventions. NurtureVR, a digital maternal mental health and educational program, leverages virtual reality to offer mindfulness, relaxation, and guided imagery to support these women.ObjectivesThis protocol aims to evaluate whether NurtureVR, a digital therapeutic, can reduce stress levels and mental health symptoms in pregnant and postpartum Black and Latina women, improve sleep, enhance pregnancy and childbirth experiences, and increase pregnancy and postpartum health literacy.MethodsThe Nurturing Moms study uses a pre- and post-intervention design with a 5-week NurtureVR program. Fifty participants, 25 expectant and 25 postpartum Black and Latina women, will be recruited through clinics, community organizations, and online platforms. The study involves three phases: baseline assessments of stress, mood, self-efficacy, demographics, and health history; daily use of NurtureVR for 15 minutes during the third trimester and six weeks postpartum; and follow-up assessments at six weeks postpartum. The program includes 49 modules on labor and delivery, stress during pregnancy, nutrition, breastfeeding, hormonal changes, 3D VR representations of fetal development, pain management simulations, and mindfulness exercises for labor. Participants will report stress, anxiety, mood, and pain levels following each VR session. Additional qualitative insights will be gathered through focus groups, and an optional survey will be administered one-year post-intervention to evaluate long-term effects.ConclusionsThe Nurturing Moms study seeks to create a more inclusive and equitable healthcare landscape, demonstrating that digital interventions like NurtureVR are essential for providing high-quality maternal care. By democratizing access to clinical research and healthcare, this decentralized trial promotes equity, improves the generalizability of findings, and accelerates the development of new treatments. The study’s innovative approach has the potential to improve maternal experiences of stress, sleep, and overall health outcomes for Black and Latina mothers and children, despite limitations such as sample size, language barriers, and the preliminary nature of a pilot and feasibility study.

10-Week Ballroom Dance Program Improves Mood and Influences Health-Related Elements in Healthy Middle-Aged Adults.

Introduction: Sedentary lifestyles remain a persistent health issue in Japan. Ballroom dancing has recently gained attention as a potential means of maintaining physical activity, but there are very few reports on Japanese subjects. Exploratory research is therefore needed to investigate the effects of ballroom dancing on the physical and mental health of sedentary middle-aged Japanese adults. The aim of this study was to assess the impact of ballroom dancing on various health-related physical and psychological outcomes in middle-aged adults compared to a control group. Methods: A parallel-group study was carried out. Thirty healthy but inactive middle-aged adults with no previous dance experience were divided into 2 groups: an intervention group which participated in a recreational level ballroom dance program for 10 weeks (60 minutes, once per week) and a control group which had no dance lessons. Subjects completed questionnaires regarding subjective mood changes and daily physical activity. Objective measures of physical fitness, oxidative stress, antioxidant capacity, and autonomic nervous system function were also assessed before (T0) and after 10 weeks (T11) of dance practice. Results: In the subjective questionnaire, the Profile of Mood States 2 (POMS®2) survey, one of the health-related indicators, T-scores of the Total Mood Disturbance (TMD) after the intervention showed a difference (P = .014) between the dance group and the control group. In post hoc tests, increases of autonomic activity and number of days of high-intensity physical activity correlated positively with a reduction in TMD in the dance group. Conclusion: Among inactive middle-aged adults, participation in weekly ballroom dance lessons for 10 weeks improved their psychological mood compared to a control group. The improvement was found to have the positive effects of activating autonomic nervous system activity and increasing high-intensity physical activity. The results suggest that ballroom dancing may be effective in improving exercise habits and physical and mental health.

Analyzing the Impact of an 8-Week Structured Physical Activity Program on Health-Related Fitness in Bhutanese Seventh-Grade Students

Objectives. This study aimed to evaluate the impact of an 8-week physical activity program (PAP) on health-related fitness (HRF) components of seventh graders in Bhutan. Its emphasis areas included assessing the program’s effects on cardiorespiratory endurance, muscular strength, muscular endurance, flexibility, and body composition. Materials and methods. Sixty-two students were allocated into two groups using simple random sampling: a control group (n = 31) following the standard physical education curriculum and an experimental group (n = 31) participating in the PAP utilizing the FITT (frequency, intensity, time, and type) principle. Fitness Gram assessments were used to measure HRF before implementing the intervention. Independent t-tests were used to compare results between groups, whereas paired t-tests were used to compare pre-test and post-test scores within groups. Results. All HRF components demonstrated notable improvements in the experimental group. Cardiorespiratory endurance increased from a mean of 23.23 to 30.57 (p <0 .05), muscular strength — from 7.47 to 12.37 (p < 0.05), muscular endurance — from a mean of 10.10 to 16.40 (p < 0.05), and flexibility — from 27.98 to 29.85 (p < 0.05). It was additionally observed an improvement in body composition, with a notable decline in BMI. Conversely, the control group showed a less significant decrease in flexibility and BMI, while demonstrating marked enhancements in cardiorespiratory endurance, muscular strength, and muscular endurance. Conclusions. The study indicates that the organized PAP was more effective than the standard physical education curriculum in improving HRF components. These findings suggest that the implementation of structured PA programs using the FITT principles can lead to enhanced physical fitness and health-related outcomes among children and young people.

Inspiratory muscle resistance combined with strength training: effects on aerobic capacity in artistic swimmers.

This study aimed to investigate the effects of combining inspiratory muscle resistance with strength training on lung function and aerobic capacity in artistic swimmers. This research constitutes a placebo-controlled randomized trial, involving a five-week walking program conducted twice a week. Fourteen female artistic swimmers were randomly assigned to either the experimental group (TG group, n = 7) or the control group (CG group, n = 7). Both groups underwent the same strength training program. The TG group performed inspiratory muscle strengthening at 50% of maximum inspiratory pressure (MIP) during strength training, whereas the CG group engaged in strength training with 15% MIP inspiratory muscle training twice a week. Pre- and post-intervention assessments included an incremental stress test, pulmonary function test, inspiratory muscle strength test, and a specialized performance test. Following the 5-week intervention, within-group comparisons revealed that the inspiratory muscle strength index, vital capacity, and forced vital capacity significantly increased in both the CG and TG groups (P < 0.01). The TG group exhibited a significant increase in minute ventilation (P < 0.05), while the CG group showed a significant increase in tidal volume (P < 0.05). Additionally, the TG group demonstrated a significant improvement in running speed at the ventilation threshold and maximum oxygen uptake (P < 0.05), along with a significant increase in tidal volume (P < 0.01). Both the CG and TG groups showed significant increases in the scores for the 50-meter diving and 25-meter torpedo (P < 0.05). Between-group comparisons showed that the TG group experienced significant improvements in the inspiratory muscle strength index, minute ventilation, running speed corresponding to maximum oxygen uptake, and 25-meter torpedo performance (P < 0.05). The findings suggest that a 5-week program combining inspiratory muscle resistance with strength training can effectively enhance the aerobic exercise capacity of artistic swimmers. Moreover, high-intensity inspiratory muscle resistance combined with strength training can improve the muscle's ability to utilize oxygen during exercise. Beijing Research Institute of Sports Science (TKSLL202201); China Clinical Trial Registry, ChiCTR2300072833, 26/06/2023.

Mechanisms of change in compassion-based programs for medical students

Medical practice exposes physicians to numerous stressors, leading to high rates of psychological distress and burnout, a problem that begins during medical school. Scientific evidence suggests that promoting compassion among physicians could improve their well-being and promote patient-centered care. However, the mechanisms underlying these benefits remain unclear. This study aimed to examine the mediators and moderators of changes in psychological distress and well-being following Compassion Cultivation Training (CCT) among medical students. A randomized controlled trial with 40 medical students assigned to an 8-week CCT program or a waitlist control group was conducted. Participants were assessed at pre-intervention, post-intervention, and a 2-month follow-up on measures of psychological distress, well-being, mindfulness, compassion, emotion regulation, and burnout. Results indicated that CCT led to significant reductions in stress and anxiety immediately after the program, mediated by improvements in emotion regulation and mindfulness skills. Gender moderated changes in stress, anxiety, depression, and well-being at post-intervention, with women benefiting more than men, though these differences were not sustained at follow-up. In conclusion, this study contributes to the growing body of literature on the benefits of compassion training in healthcare and provides insights into the mechanisms through which compassion could support physicians and medical students.

Assessment of atrial strain variations in amateur runners: A 10-week unsupervised training program and half-Marathon impact study using 2D and speckle-tracking echocardiography

BackgroundCompetitive running leads to cardiac remodeling and functional changes in cardiovascular haemodynamics in professional runners. Data on atrial changes in amateur runners completing a half-marathon are limited. The study sought to analyze the impact of training and a 21.0975-km run on echocardiographic parameters of left (LA) and right (RA) atrial anatomy and function in recreational runners. MethodsThe study group comprised 52 amateur runners [mean age 32.96 (5.12) years], including 32 men. Echocardiographic evaluations were performed at three stages: prior to the ten-week unsupervised training, and then before and after the run. Morphological and functional parameters were assessed using two-dimensional imaging, Doppler, and speckle-tracking technique. ResultsDuring the training period, both LA dimension [31.87 mm vs. 33.96 mm; p < 0.001] and LA volume [59.00 ml vs. 68.00 ml; p < 0.001] increased and no changes were found for RA morphological parameters. Ten weeks of preparatory training resulted in an increase in LA contractile strain (LASct) [10.50 % vs. 11.00 %; p = 0.030], without affecting the RA function. Change of LASct was particularly pronounced in young women (<32 years; p = 0.029). Half-marathon performance decreased the LA volume. ConclusionsAmateur training for 21.0975-km run remodels LA and enhances LA active contractile function (especially in young women) without influencing RA. The half-marathon decreases LA volume and does not affect RA morphology and function in recreational runners.

Efficacy of an Online Self-Management Program for Chronic Burn Pain: A Randomized Controlled Trial of the Take Charge of Burn Pain Program

This randomized controlled trial investigated the effectiveness of an online self-management program, "Take Charge of Burn Pain (TCBP)," for 96 individuals living with chronic burn pain. Participants were randomly assigned to either the 7-week TCBP program integrating cognitive-behavioral therapy techniques, pain education, and self-management strategies or an attention control group focused on general burn recovery information. Assessments conducted at baseline, post-treatment, and 2 and 5-month follow-ups included measures of pain severity, pain interference, pain self-efficacy, posttraumatic stress disorder symptoms, and depression. Compared to the control group, participants in the TCBP program demonstrated greater reductions in pain severity (mean difference: -1.24, 95% CI: -1.93 to -0.55, p = 0.0007) and pain catastrophizing (mean difference: -5.41, 95% CI: -10.33 to -0.49, p = 0.0318) post-treatment when adjusting for key variables. At the two-month follow-up, the TCBP group showed significant improvements in pain interference (P = 0.0123), self-efficacy (P = 0.0269), functional abilities (P = 0.0014), and social role participation (P = 0.0498) compared to the control group. Treatment effects were not sustained at five-month follow-up. Participants in both groups reported high levels of satisfaction with the online intervention, with the majority finding the program helpful, easy to use, and willing to recommend it to others with pain. Findings suggest preliminary support for short-term benefits of TCBP for managing certain facets of chronic burn pain. This underscores the need to refine digital approaches to maintain and promote long-term improvements. The potential of self-guided online psychological interventions to enhance pain coping strategies for burn survivors persists.

Myocardial Disorders in BDNF-Deficient Rats: Limited Recovery Post-Moderate Endurance Training.

The study aimed to determine whether heterozygous BDNF-deficient (BDNF-knockout, SD-BDNF) rats exhibit pathological changes in the myocardium and to assess whether a 5-week moderate-intensity endurance training program can reverse adverse changes in the heart muscle. Experiments were conducted on four groups of rats: control wild-type, control BDNF knockout, trained wild-type and trained BDNF knockout. Knockout rats were selected due to the presence of symptoms resembling metabolic syndrome in serum and liver while 5-week moderate endurance training was used as an intervention targeted at restoring heart function. Measurements of BDNF/Trk-B concentrations and molecules levels and activities, such as cardiac specific enzymes like creatine kinase and creatine kinase myocardial band, lipids as total cholesterol, low-density lipoprotein and triglycerides, metabolic enzymes including alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase and lactate dehydrogenase and interleukin-1 were carried out in myocardium homogenates. In BDNF-deficient rats, the myocardium showed significantly reduced lipid concentrations, decreased metabolic and cardiac enzyme activity, and elevated Trk-B levels, all of which are indicative of myocardial ischemia or hypoxia. These changes in critical biomarkers were consistent with those earlier observed in the livers of BDNF-deficient rats, suggesting a link between the liver and cardiac function. Moderate endurance training led to an increase in creatine kinase activity in the myocardium of trained rats, suggesting increased production and utilization of energy required for myocardial contraction in trained wild-type and knockout populations of rats. BDNF-deficient rats exhibited numerous myocardial abnormalities, most of which were not reversible after moderate-intensity endurance training. These findings provide a basis for a deeper understanding of the mechanisms underlying myocardial disorders in BDNF-deficient rats, which appear to be a suitable model for studying various aspects of metabolic disorders.

Sustained Effect Of Neurocreative Music Therapy On Upper Limb Abilities, Spasticity, Selective Control And Quality Of Life In Cerebral Palsy: A Case Report

Abstract This case report, presents the sustained effect of Neurocreative Music Therapy (NCMT) which a uniqe music therapy approach on the upper limb in an individual with cerebral palsy (CP). Our case is a 19-year-old individual with hemiparetic CP and she was included in the 8-week NCMT application program. Before the application, a phenomenological interview was conducted in accordance with the principle of the NCMT approach, which prioritizes the needs and pleasures of the individual. Before and immediately after the 8-week NCMT application, the patient's spasticity was assessed with the Modified Ashwort Scale, selective motor control with the Selective Control of the Upper Extremity Scale, upper limb abilities in daily activities with the ABILHAND-Kids, and quality of life with the Pediatric Quality of Life Inventory CP Module 3.0. As a result of the assessments, an individual-specific music therapy program was planned and implemented. The outcome measurements made immediately after the NCMT application were repeated in the 4th and 8th weeks following the end of the application. According to the results of the scales, it was observed that spasticity decreased, selective motor control increased, upper limb abilities improved, and quality of life increased. The obtained improvements were generally maintained in the 4th week following the end of the therapy. It was observed that there was a decrease in the sustainability of the effect in the 8th week following the end of the therapy in other measurement parameters other than quality of life. As a result, we concluded that NCMT is an effective approach in the rehabilitation of individuals with CP and that its effects may be transferred to the post-rehabilitation period.

Chronic effects of a static stretching intervention program on range of motion and tissue hardness in older adults.

Clinically, knowing whether a static stretching (SS) intervention program conducted for several weeks can reduce passive muscle stiffness is important. Still, only a few previous studies have evaluated the chronic effects of an SS intervention program in older adults, and the potential relationship between ROM changes and muscle stiffness changes is still unclear. This study aimed to investigate the effects of a 10- week SS intervention partially supervised program on joint range of motion (ROM) and tissue hardness in older adults. The SS intervention program was conducted at least three times a week for 10 weeks in the ankle plantar flexor muscles of 24 community-dwelling older adults (73.8 ± 5.1 years; height: 156.0 ± 6.8 cm; body mass: 52.7 ± 8.0 kg). The SS intervention program consisted of 4 × 30-s repetitions. Ankle joint dorsiflexion (DF) ROM and tissue hardness of the medial gastrocnemius were measured before and after the 10-week SS intervention program. The results showed that the 10-week SS intervention program significantly increased DF ROM (+9°, p < 0.01, Cohen's d = 1.37) and decreased tissue hardness (-0.9, p = 0.04, Cohen's d = -0.27). However, there was no significant correlation between these changes (r = 0.086, p = 0.561). The results of this study suggest that a 10-week SS intervention program can effectively increase DF ROM and decrease tissue hardness but that the increase in DF ROM is related to stretch tolerance rather than changes in tissue hardness.

Effects of electrical muscle stimulation exercise on lower limb muscles and lumbar movement in older adults with disabilities: A pre- and post-test controlled experimental study

In older adults with disabilities, muscle weakness reduces mobility and causes postural issues. Electrical muscle stimulation (EMS) training is effective for increasing strength by inducing involuntary skeletal muscle contractions. Thus, this study aimed to examine changes in lumbar movement, muscle activity during walking, and maximum muscle strength of lower-limb joints based on an 8-week EMS exercise program for older adults with physical disabilities. Sixteen older adults (aged 56–78 years) with physical disabilities were selected and randomly assigned to either the exercise group (EG, n = 8) or the control group (CG, n = 8). EG participants were instructed to wear EMS suits and participate in an elastic band and bare-body exercise program, whereas CG participants performed the exercise program without the EMS suits. Lumbar range of motion (ROM), body circumference, partial volume, maximum muscle strength, and muscle activity were measured. Statistical analysis was performed using SPSS 28.0 for Windows, with the critical value of α = 0.05. Compared to CG participants, EG participants had a superior ROM, body volume, partial volume, maximum muscle strength (knee joints), and muscle activity while walking. These positive outcomes highlight the efficacy of combining EMS with an exercise program for strength and rehabilitation training in older adults with physical disabilities.

Trajectories and predictors of adolescent purpose development in self-driven learning.

Purpose offers several important benefits to youth. Thus, it is necessary to understand how a sense of purpose develops in supportive contexts and what psychological resources can help. From 2021 to 2022, this study investigated purpose change among 321 youth (Mage = 16.4 years; 71% female; 25.9% Black, 33.3% Asian, 15.6% Hispanic/Latinx, 13.4% White, 9.7% multiracial) participating in GripTape, a ~10-week self-driven learning program. Many youth started with high initial purpose that increased throughout enrollment (Strengthening), whereas others began with slightly lower purpose that remained stable (Maintaining). For each unit increase in baseline agency, youth were 1.6x more likely to be classified as Strengthening. As such, agency may be a resource that helps youth capitalize on certain types of environments.

Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings.

Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. Metabolic profiles are key features in longevity and have been associated with both age and age-related diseases. We previously reported an increase in the telomere length in healthy female subjects when Ramadan fasting was combined with physical training. This study aims to characterize the metabolic signature differentiating the combined effects of exercise and fasting from exercise alone and explore the correlations with the previously reported telomere length changes. Twenty-nine young, non-obese, and healthy female subjects were previously randomized into two groups: one group followed a 4-week exercise program, while the other group followed the same 4-week exercise program but also fasted during Ramadan. Metabolic profiles were assessed pre- and post-intervention using untargeted metabolomics. Our results showed a significant decrease in many lipid metabolites in the exercise-while-fasting group, particularly ceramides. Our study sheds light on the dynamic changes in lipid metabolism and its potential role in inflammation and age-related diseases, and contributes to the broader understanding of how lifestyle factors can influence cellular aging and metabolic health.

“It Took Away the Trauma of Failing”: A Mixed Methods Feasibility Trial of an Open Goals Physical Activity Program

ABSTRACT Open goals (e.g. to “see how many steps you can reach today”) may be a promising strategy for promoting physical activity. The findings from initial studies, typically based on single sessions of exercise, showed that open goals can produce at least as much activity as specific goals (e.g. to reach 10,000 steps a day), while promoting more positive experiences and higher intentions to repeat the activity, especially among less active individuals. However, the feasibility of using open goals over a longer duration remains unclear. Therefore, in this study, we examined the feasibility of using open goals in a 10-week step-based physical activity program. A single-arm mixed methods design was used, involving 15 healthy adults (13 female; Mage = 42.53) with low to moderate physical activity levels. Participants were provided with a pedometer, diary, and open goals for each week, alongside brief support sessions. The feasibility domains assessed included recruitment, acceptability, adherence, and retention. Quantitative methods assessed physical activity, enjoyment, and self-efficacy, while supplementary qualitative methods explored participants’ perceptions of open goals. The study showed high recruitment and retention rates, increased physical activity, and positive psychological experiences, indicating the feasibility of the 10-week open-goal program. Secondary outcomes suggest that open goals may function by increasing enjoyment and self-efficacy while decreasing negative outcomes such as pressure, guilt, and failure. The findings indicate that using open goals in longer-term physical activity programs is feasible, expanding on the limitations of previous single-session designs, and offering recommendations for future trials.