ABSTRACT: Aujeszky’s Disease (AD) is a highly infectious swine disease caused by Suid herpesvirus 1 (SuHV 1). The present study evaluated the biosafety of commercial swine farms and carried out the first serological survey for Aujeszky’s Disease in Espírito Santo State, Brazil. A total of 55 farms in 27 municipalities of the state were selected, where 416 swine serum samples were collected to be submitted to serological diagnosis for AD. Finally, a survey was carried out using a questionnaire to obtain information on the biosecurity of the farms. The results by the ELISA technique indicated the absence of antibodies for AD. Regarding the biosecurity of the farms, 56.4% of the farms did not meet the requirement of internal isolation, 67.3% did not have changing rooms, 72.7% did not provide specific clothing for employees and visitors, 85.5% did not require visitors bathe to access the sheds and only 10.9% of the farms controlled the flow of visitors and vehicles accessing the property. Another noteworthy factor is that only 25.5% of the farms had an area to quarantine replacement animals and 69.1% had an access ramp located close to the animal pens. With the results, it was concluded that there is a need to improve biosecurity measures on commercial farms in the state of Espírito Santo and that there was no presence of Aujeszky’s Disease in the evaluated animals.

Objective: to investigate the factors that exert an influence on health literacy in patients with coronary artery disease. Methods: a crosssectional study, including 122 patients with coronary diseases (60.7% male; 62.07 ± 8.8 years old). Health literacy and specific knowledge about the disease were evaluated through interviews with the participants by means of the Short Test of Functional Health Literacy in Adults and the Short version of the coronary artery disease education questionnaire. The data were described by means of central tendency measures and frequencies. The factors that exert an influence on health literacy were determined by means of a linear regression model. The significance level adopted was 5%. The study was approved by the Research Ethics Committee. Results: age and arterial hypertension presented an inverse and significant relationship with health literacy. On the other hand, higher schooling levels and having a job were associated with better scores in the health literacy instrument. Specific knowledge about the disease did not exert any influence on health literacy. The variables included in the regression model explained 55.3% of inadequate literacy. Conclusion: this study, knowledge about the disease exerts no influence on health literacy: however, the professionals should consider the sociodemographic and clinical factors to plan the interventions.

Objetivo: investigar os fatores que influenciam o letramento em saúde em pacientes com doença arterial coronariana. Método: estudo transversal, incluindo 122 pacientes com coronariopatias (60,7% do sexo masculino; 62,07±8,8 anos); letramento em saúde e conhecimento específico da doença foram avaliados por meio de entrevista com os participantes, pelo Short Test of Functional Health Literacy in Adults e Short version of the coronary artery disease education questionnaire. Os dados foram descritos por medidas de tendência central e frequências. Fatores que influenciam o letramento em saúde foram determinados por modelo de regressão linear. O nível de significância adotado foi de 5%. O estudo foi aprovado pelo Comitê de Ética e Pesquisa. Resultados: idade e hipertensão apresentaram uma relação inversa e significativa com letramento em saúde. Por outro lado, maior escolaridade e estar empregado associaram-se com maiores pontuações no instrumento de letramento em saúde. O conhecimento específico da doença não influenciou o letramento em saúde. As variáveis do modelo de regressão explicaram 55,3% do letramento inadequado. Conclusão: no presente estudo o conhecimento sobre a doença não influência o letramento em saúde, mas os profissionais devem considerar os fatores sociodemográficos e clínicos para planejar as intervenções.

to investigate the factors that exert an influence on health literacy in patients with coronary artery disease. a crosssectional study, including 122 patients with coronary diseases (60.7% male; 62.07 ± 8.8 years old). Health literacy and specific knowledge about the disease were evaluated through interviews with the participants by means of the Short Test of Functional Health Literacy in Adults and the Short version of the coronary artery disease education questionnaire. The data were described by means of central tendency measures and frequencies. The factors that exert an influence on health literacy were determined by means of a linear regression model. The significance level adopted was 5%. The study was approved by the Research Ethics Committee. age and arterial hypertension presented an inverse and significant relationship with health literacy. On the other hand, higher schooling levels and having a job were associated with better scores in the health literacy instrument. Specific knowledge about the disease did not exert any influence on health literacy. The variables included in the regression model explained 55.3% of inadequate literacy. this study, knowledge about the disease exerts no influence on health literacy: however, the professionals should consider the sociodemographic and clinical factors to plan the interventions.

This study aimed to evaluate in vivo the use of the extract from the leaves of Melia azedarach in the ethyl acetate fraction at a concentration of 150µg/mL as an antiretroviral treatment against small ruminant lentiviruses (SRLV) in goat colostrum, and milk with a 90-min action. Two groups of six kids were treated with the extract. One group received three supplies of colostrum from does naturally positive for SRLV, treated with the ethyl acetate fraction of M. azedarach (EAF-MA) for three days, while the other group consumed milk from does also carrying the virus with the respective extract twice a day for five days. After undergoing treatment, all animals began to receive thermized milk until weaning (60days) and were monitored for six months using nested polymerase chain reaction (nPCR) and western blot (WB) tests. The study revealed cumulative percentages of positive animals in WB or nPCR in the milk group of 66.66% on the seventh day, 83.33% in the following week, and 100% at 120days, while the colostrum group showed values of 66.66% at 14days, 83.33% at 90days, and 100% at 120days. Variation and intermittency were observed in viral detection, but all animals tested positive in WB or nPCR at some point. A potential delay in infection was observed, which was more significant in the colostrum group. The need for the combination of serological and molecular tests for a more efficient detection of the disease is also emphasized.

The widespread use of pesticides in agriculture has been linked to declines in bee populations worldwide. Imidacloprid is a widely used systemic insecticide that can be found in the pollen and nectar of plants and has the potential to negatively impact the development of bee larvae. We investigated the effects of oral exposure to a realistic field concentration (20.5 ng g−1) of imidacloprid on the midgut and fat body of Apis mellifera worker larvae. Our results showed that larvae exposed to imidacloprid exhibited changes in the midgut epithelium, including disorganization of the brush border, nuclear chromatin condensation, cytoplasm vacuolization, and release of cell fragments indication cell death. Additionally, histochemical analysis revealed that the midgut brush border glycocalyx was disorganized in exposed larvae. The fat body cells of imidacloprid-exposed larvae had a decrease in the size of lipid droplets from 50 to 8 μm and increase of 100 % of protein content, suggesting possible responses to the stress caused by the insecticide. However, the expression of de cdc20 gene, which plays a role in cell proliferation, was not affected in the midgut and fat body of treated larvae. These results suggest that imidacloprid negatively affects non-target organs during the larval development of A. mellifera potentially impacting this important pollinator species.

Arterial hypertension is a non-communicable, asymptomatic chronic disease that is entirely linked to the high rates of morbidity and mortality that affect the quality of life of the elderly. We seek to understand how arterial hypertension can be treated to reduce the number of deaths in elderly people and describe the role of the nursing team in controlling arterial hypertension. This is an integrative review established by Cooper, the searches took place in the Virtual Health Library and Pubmed, using the descriptors “hypertension”, “nurse”, “prevention”, “mortality associated with each other by the Boolean operator “and”, in the period from 2016 to 2021, resulting in the initial search of 972 articles that after applying the selection criteria and reading in full, 38 remained that made up the research corpus. The socio-environmental and genetic conditions, which when related to senescence and unhealthy life habits, imply the triggering of hypertension, a health problem with loss of quality of life and increased morbidity and mortality. Nursing professionals who work in primary care are the crucial link in the early detection and development of actions aimed at health care, aiming to control the blood pressure levels of patients affected by AH, disseminating information aimed at health education.

The facial region is important for patients’ socialization. Therefore, the mutilation of this area should be rehabilitated quickly and effectively. The objective of this review was to analyze which software and equipment are most commonly used for the acquisition, manipulation of images, and printing of prototypes and facial prostheses, correlating with the type of prosthesis. The search strategy was customized for 7 different databases: LILACS, Embase, Web of Science, PubMed, Scopus, OpenGrey, and Google Scholar. Articles were selected based on inclusion and exclusion criteria, with abstract and full article readings performed independently by 2 authors, with disagreements resolved through a consensus meeting. The risk of bias for each included article was analyzed using JBI. Subsequently, data such as the type of prosthesis manufactured, software used, equipment for defect image acquisition, and printing equipment were collected. The data were tabulated, and a descriptive analysis was performed. Most studies reported the fabrication of nasal prostheses, followed by auricular and ocular prostheses. The primary technology chosen for patient defect image acquisition was computed tomography, and for image manipulation, Materialise Mimics software was commonly used. Additionally, a significant portion of the studies reported the use of direct three-dimensional printing. In conclusion, there is a significant heterogeneity among articles in the equipment and software used, and there is no clear relationship between these factors and the type of prosthesis manufactured.

This article is an integrative synthesis of two studies conducted with teachers of inclusive classes in Brazil and discusses the reality of inclusive teaching in contemporary Brazilian schools. The goal is to foster reflection about emotions and teaching practices in inclusive contexts based on Vygotsky's Cultural-Historical Psychology. The results reveal that the practices express the Teacher's meanings and emotions to the inclusive process, affecting the teaching-learning processes. We conclude that the implementation of inclusive systems implies understanding the singularities of each real subject that is part of the school. Therefore, it is essential to recognize emotions and rethink practices, building new paths that promote and ensure real inclusion.

The occurrence of gastrointestinal parasites in cats is reported with great frequency, especially when it comes to animals with outdoor access, or living in overcrowded environments, such as catteries and shelters. Infection byIsospora spp in cats begins with the ingestion of sporulated oocysts in the environment or tissues from other infected intermediate vertebrate hosts. Diagnosis is based on the detection of oocysts in cat feces and clinical signs. The recommended treatment for coccidiosis in cats is sulfonamides. Other drugs have been studied as secondary lines of treatment, which is the case of ponazuril and toltrazuril, which have been used in animals to treat isosporosis, toxoplasmosis, neosporosis and equine protozoal meningoencephalitis. There are anecdotal reports of the use of ponazuril in treating Isospora spp. In this study, 21 cats were treated with ponazuril, which proved effective in controlling the disease, since 100% of the cats treated were negative in the coproparasitological examination after the three days of treatment with a dose of 50 mg/kg SID. Furthermore, the animals had considerable improvement in stool consistency after the dosing period.