- Research Article
- 10.4103/mtsm.mtsm_31_25
- Oct 1, 2025
- Matrix Science Medica
- Jinkal Jain + 3 more
Background: Conductive hearing loss (CHL) is a common presentation in an otologic clinic. CHL occurs due to pathology in the middle ear and external auditory canal. Chronic otitis media (COM) is a common clinical entity which manifest CHL. This study aims to evaluate the correlation between otological and audiological findings with intraoperative findings in patients with CHL. Methods: This is a cross-sectional study conducted between July 2024 and August 2025. This study included 80 patients diagnosed with CHL after a comprehensive evaluation process that included detailed history-taking, clinical examination, and audiological assessments. The study participants are divided into two groups, with each group consisting of 40 participants. Results: The mean age of the participants was 32.0 ± 10.62 years. The most commonly reported symptom was ear discharge (66.3%), followed by hearing impairment (33.8%). Among participants with a perforated tympanic membrane, 62.5% exhibited bilateral involvement, whereas 37.5% had unilateral involvement. Conversely, in the intact tympanic membrane group, 37.5% had bilateral involvement, while 62.5% had unilateral involvement, indicating a reversed pattern. In contrast, among inactive perforation cases ( n = 21), only a single case (4.8%) exhibited incus erosion, which was associated with an anterior perforation. Conclusion: The most common cause of CHL in the present study is COM. CHL is more pronounced in patients of COM with subtotal perforation who also exhibited a higher degree of ossicular damage.
- Research Article
- 10.4103/mtsm.mtsm_19_25
- Oct 1, 2025
- Matrix Science Medica
- Himanshu Kalia + 3 more
Vibration has been used in therapy for a long time – sometimes to help bones heal, sometimes to calm the mind through music. What’s interesting is that these two very different techniques might actually share a common purpose. Whether it’s through mechanical pulses applied to tissues or soothing sounds that affect the brain, both seem to play a role in recovery. However, they’re often studied in isolation, which means we may be missing out on something bigger. We went through existing literature across biomechanics, neuroscience, and clinical rehab to map how mechanical vibrations affect cells and tissues, and how acoustically delivered vibration (like music or sound therapy) influences brain function and mood. Studies on low-magnitude, high-frequency vibrations, and music therapy were included. Mechanical vibration helps cells grow, tissues repair, and bones get stronger – especially when the frequency is tuned just right. Meanwhile, sound-based therapies affect hormones such as dopamine and cortisol, improving emotional well-being and reducing pain. Some studies hint that combining both methods could be useful in complex cases like postsurgical rehab or chronic pain. Mechanical and acoustic vibrations are the two sides of the same coin. One works through the body, the other through the brain – but both aim to help people feel better and heal faster. Combining them isn’t just an interesting idea – it might be the key to more holistic, effective care. More real-world testing, smarter devices, and clear protocols will be needed to turn this into a reliable part of clinical practice.
- Research Article
- 10.4103/mtsm.mtsm_5_25
- Oct 1, 2025
- Matrix Science Medica
- Samia Muhammad Salem Mira
Background: This paper presents an analytical study of the characteristics of participants in a health study aimed at understanding the relationship between several demographic and health factors. Objectives: To analyze how demographic variables and health-related conditions such as hypertension, diabetes, stroke history, smoking, and chest infections relate to health outcomes. Methods: Data were collected on gender, age, and selected health conditions. Participants were distributed based on these variables. Logistic regression analysis was applied to identify factors influencing the likelihood of developing specific health conditions. Results: The study revealed gender differences (61.8% males and 38.2% females) and a higher concentration of participants in older age groups. Logistic regression analysis showed negative effects for chest infections, smoking, blood pressure, and diabetes, while male gender had a positive effect. Conclusions: Understanding complex interactions among demographic and health variables is essential. The study emphasizes the need for further research to clarify their broader effects on public health.
- Research Article
- 10.4103/mtsm.mtsm_6_25
- Oct 1, 2025
- Matrix Science Medica
- Santosh Kumar Swain
Cochlear implantation is considered a well-established treatment for severe-profound sensorineural hearing loss. Hearing loss often affects negatively to the quality of life (QOL). It may be associated with impaired speech, social isolation, psychological and professional development, and feelings of inferiority. These factors can result in emotional problems such as low self-esteem, loneliness, and depression. Bilateral profound hearing loss often results in impaired interpersonal relationships. After cochlear implantation, prelingual deafness patients’ QOL and speech recognition may have greatly improved. Despite this, there is little study on the satisfaction level in cochlear implantees who had long periods of hearing deprivation. Not much study has been done on the implantees’ QOL. This review article discusses the prevalence, cochlear implantation related comorbidities, factors of cochlear implant recipients affecting QOL, social acceptance, psychological acceptance, issues in the elderly age, complications associated with cochlear implantation, postcochlear implant status, and QOL assessment related to cochlear implant surgery.
- Research Article
- 10.4103/mtsm.mtsm_12_25
- Oct 1, 2025
- Matrix Science Medica
- Luis Rafael Moscote-Salazar + 4 more
- Research Article
- 10.4103/mtsm.mtsm_10_25
- Jul 1, 2025
- Matrix Science Medica
- Luis Rafael Moscote-Salazar + 5 more
The human nervous system is somewhat of an electric organ, sensitive to electromagnetic fields. Earlier research has already showed that an alteration in the brain can be caused by exposure to electromagnetic fields. Unidentified aerial phenomena (UAP), which was previously called unidentifiable flying objects, are gaining ground, and their study is not only with an extraterrestrial or technological significance but also with a consideration in its potential psychological and neurological effects to humans. While there is limited direct evidence supporting the association of UAP sightings with neurological disorders, anecdotal reports may suggest that those encountering UAPs may develop psychological and neurological alterations. This paper, therefore, critically reviews the potential neurological impacts of UAP encounters and the attendant challenges for future research in the field.
- Research Article
- 10.4103/mtsm.mtsm_3_25
- Jul 1, 2025
- Matrix Science Medica
- Santosh Kumar Swain
The development of mobile phones has been one of the fastest in the history of technological progress. Today, mobile phones are an essential part of everyday life. Mobile phones emerged in the early 1980s, and their usage has grown rapidly since then. There is increasing worry about the harmful effects of long-term use of mobile phones on human health. The inner ear, which is closest to the phone during conversations, absorbs the most electromagnetic radiation (EMR). The hair cells in the cochlea are particularly vulnerable to damage compared to other structures. Thus, the whole auditory system including the cochlea and auditory nerve is particularly at risk following prolonged use of mobile phones due to its EMR. Other than hearing impairment, prolonged use of mobile phones also affects the mental and physical condition of human beings due to its overuse. The ear that is frequently used during mobile phone calls, called as dominant ear that is at higher risk for hearing loss. Chronic use of mobile phones often reveals high-frequency hearing impairment in the dominant ear compared to the nondominant ear. The aim of this review is to summarize and critically evaluate the evidence of hearing loss due to chronic use of mobile phones.
- Research Article
- 10.4103/mtsm.mtsm_14_25
- Jul 1, 2025
- Matrix Science Medica
- Kavitha Yogini Duraisamy + 3 more
Background: Ruptured endometriotic cysts are a rare but significant cause of acute abdominal pain in women of reproductive age. Prompt recognition and management are crucial to prevent complications and preserve fertility. Case Series: This report presents a series of three cases of ruptured endometriotic cysts in women aged between 25 and 35 years, each presenting with acute abdominal pain. Clinical evaluation, imaging, and surgical exploration confirmed the diagnosis. All patients underwent laparoscopic intervention, which revealed hemoperitoneum and ruptured ovarian endometriomas. Histopathological examination confirmed endometriosis. Postoperative recovery was uneventful in all cases, and patients were managed with hormonal therapy to prevent recurrence. Conclusion: Ruptured endometriotic cyst should be considered in the differential diagnosis of acute abdomen in women of reproductive age, especially those with a history of dysmenorrhea or endometriosis. Laparoscopy remains a valuable diagnostic and therapeutic tool in such cases.
- Research Article
- 10.4103/mtsm.mtsm_30_24
- Jul 1, 2025
- Matrix Science Medica
- Luis Rafael Moscote-Salazar + 3 more
- Research Article
- 10.4103/mtsm.mtsm_17_25
- Jul 1, 2025
- Matrix Science Medica
- Busira Adesina Tijani + 8 more
Background: Umbilical cord blood is a rich source of Cluster of Differentiation (CD) 34 + stem cells with therapeutic value, but its use in Nigeria is limited due to inadequate cryopreservation infrastructure and underdeveloped cord blood banking systems. Objective: This study aimed to assess the viability of CD34 + stem cells in cord blood after long-term storage at ultra-low temperature. Methods: In this longitudinal study, cord blood was collected and cryopreserved at −190°C in a liquid nitrogen tank. CD34 + stem cell viability was assessed biweekly over 48 weeks using flow cytometry. Data were analyzed with SPSS to evaluate viability trends and predict future cell preservation. Results: Fifty postpartum women (mean age: 32.4 ± 5.91 years) participated. Baseline CD34 + counts averaged 330 cells/µL, declining steadily to about 220 cells/µL over 48 weeks. Forecasting predicts a continued gradual decline, with viability potentially lost after approximately 200 weeks if current trends persist. Conclusion: CD34 + stem cells remain viable after 48 weeks at −190°C, with viability expected beyond 3 years, confirming the effectiveness of ultra-low-temperature storage. This demonstrates the potential for sustainable cord blood banking in Nigeria, where funding is limited for its establishment. To fully realize this opportunity, increased public awareness, healthcare training, supportive policies, and further research on the optimization and clinical application are necessary.