Sort by
Articulating sustainable transitions, food justice and food democracy: Insights from three social experiments in France, Belgium and Brazil

AbstractTransitions to sustainable consumption and production patterns now appear as a widely acknowledged necessity for contemporary food systems. Sustainable transition processes raise major issues of social justice as they often exclude some actors and social groups, as the literature on alternative food networks has amply shown. Based on three case studies anchored in different national contexts (France, Brazil and Belgium), which all emerged at the interface of civil society and public policy, the aim of this article is to show how their promoters try to tackle together sustainable transitions, food justice and food democracy, and thus make food system transitions not only sustainable but also socially just. They adopt on the one hand, an analytical stance on transitions to more sustainable food practices, on inequalities of access and on participation, and on the other hand, an experimental stance leading them to put to test specific mechanisms to support these transitions, to alleviate food injustice and to favour participation and thus also food democracy. We show that it is by combining these analytical and experimental stances that these social experiments succeed to different degrees in articulating sustainable transitions, food justice and food democracy.

Relevant
Candida albicans and Antifungal Peptides.

Candida albicans, a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human health and disease. As a commensal organism, it normally resides harmlessly within the human microbiota. However, under certain conditions, C.albicans can transition into a pathogenic state, leading to various infections collectively known as candidiasis. With the increasing prevalence of immunocompromised individuals and the widespread use of invasive medical procedures, candidiasis has become a significant public health concern. The emergence of drug-resistant strains further complicates treatment options, highlighting the urgent need for alternative therapeutic strategies. Antifungal peptides (AFPs) have gained considerable attention as potential candidates for combating Candida spp. infections. These naturally occurring peptides possess broad-spectrum antimicrobial activity, including specific efficacy against C.albicans. AFPs exhibit several advantageous properties, such as rapid killing kinetics, low propensity for resistance development, and diverse mechanisms of action, making them promising alternatives to conventional antifungal agents. In recent years, extensive research has focused on discovering and developing novel AFPs with improved efficacy and selectivity against Candida species. Advances in biotechnology and synthetic peptide design have enabled the modification and optimization of natural peptides, enhancing their stability, bioavailability, and therapeutic potential. Nevertheless, several challenges must be addressed before AFPs can be widely implemented in clinical practice. These include optimizing peptide stability, enhancing delivery methods, overcoming potential toxicity concerns, and conducting comprehensive preclinical and clinical studies. This commentary presents a short overview of candidemia and AFP; articles and reviews published in the last 10years were searched on The National Library of Medicine (National Center for Biotechnology Information-NIH-PubMed). The terms used were C.albicans infections, antimicrobial peptides, antifungal peptides, antifungal peptides mechanisms of action, candidemia treatments and guidelines, synthetic peptides and their challenges, and antimicrobial peptides in clinical trials as the main ones. Older publications were cited if they brought some relevant concept or helped to bring a perspective into our narrative. Articles older than 20years and those that appeared in PubMed but did not match our goal to bring updated information about using antifungal peptides as an alternative to C.albicans infections were not considered.

Open Access
Relevant