A 50-day-old male Maltese puppy was presented with difficulty in defaecation. Based on the clinical signs, and physical and radiographic examinations, including computed tomography, his condition was diagnosed as hypospadias, along with atresia ani and urethrorectal fistula. Hypospadias is a congenital malformation of the urethra that is relatively uncommon in dogs, while atresia ani is a rare congenital anomaly of the rectum and anus. An additional anatomic abnormality that can be associated with atresia ani is a fistula between the urogenital tract and rectum. After appropriate surgical procedures, the puppy recovered and defaecation via the anus was restored.

The resistance of puppies to the diabetogenic effect of administered growth hormone is well known. The possibility that this involves an adaptive increase in insulin secretion was explored by determining the effect of injected growth hormone on plasma insulin concentration at various age periods. Bovine growth hormone (1 mg/kg per day for 4 days) administered to 5-month-old puppies had no effect on plasma glucose or insulin levels nor on the effectiveness of injected insulin to lower plasma glucose levels. At 8 and 12 months of age the growth hormone regimen increased plasma glucose and insulin levels and produced a resistance to the hypoglycemic effect of injected insulin. It is evident that the difference between the puppy and adult in response to growth hormone is not due to excessive secretion of insulin by the puppy.

A rupture of one uterine horn at the region of small curvature and placentation was observed in a pregnant 8-year old Schnauzer bitch carrying a single foetus. It occurred at its second parturition. The first whelping at the age of 3 years had been without complications and the bitch reared eleven puppies. The uterine rupture occurred at the puppy’s umbilical cord. An urgent obstetrical examination revealed one dead foetus in anterior presentation and ventral position. Caesarean delivery was indicated. Evisceration of puppy’s intestine through its ruptured abdominal wall at the umbilical cord could be observed through the uterine wall rupture of 1.5 cm in diameter. The bitch underwent hysterectomy and recovered without complications.

Histopathological investigation was conducted on both inner ears from a 4.5-month-old Rottweiler puppy with electrophysiologically confirmed bilateral deafness. The lesions were restricted to the organ of Corti and spiral ganglion that both displayed severe degenerative changes. The outer hair cells were less affected than the inner hair cells. The number of spiral ganglion neurons was reduced, and remaining neurons were altered. The basal and middle cochlear turns were more affected than the apical one. The vestibules were normal. Immunostaining with calbindin, calretinin, S100A1 and S100A6 polyclonal antisera was helpful in identifying different cell-types in the degenerated cochlea. The early and severe spiral ganglion cell degeneration is an uncommon finding no matter the species. Such lesions bear significance within the frame of cochlear implants technology for deaf infants.

Recent results obtained by Smith and Engle1 by daily hypophyseal homeo and heterotransplants in mice and rats led to an investigation of the effect of daily injections of fresh rabbit pituitary gland on an hypophysectomized puppy. Aschner2 published striking photographs of hypophysectomized puppies of various ages which had remained infantile in appearance and size until sacrificed.Evans and Long3 found that fresh anterior lobe fluid given intraperitoneally to immature rats produced gigantism. Later, this extract was found to stimulate hypophysectomized rats to normal growth but failed to affect their sex glands. Smith,4 using fresh pituitary glands of rats, was able completely or in large measure to cure the disabilities arising from hypophysectomy in immature rats. Smith and Engle5 were able to induce precocious sexual maturity both in immature and in hypophysectomized rats, in 2 animals within 36 hours, by these fresh daily transplants. By means of the intracranial approach of Dandy and Reichert6 a tot...

AbstractThe development of the adrenergic innervation of the puppy kidney from birth to two months of age was studied with the fluorescence histochemical method of Falck and Hillarp in conjunction with chemical analyses for catechol‐amines in the cortex and medulla of the kidney. At birth adrenergic fibers were found entering the kidney with the renal arteries and following the arterial supply into the inner cortex. In this area the fibers were found in association with the interlobular arteries and afferent arterioles. Fibers were also seen in the neogenic zone of the cortex until the fourteenth day after birth when this area disappeared. From the fourteenth to fifty‐sixth day the adrenergic fibers were found extending to the interlobular arteries and afferent arterioles of the developing cortex. The levels of norepinephrine measured in the cortex during the first two months after birth reflected the increasing number of adrenergic nerves. In the medulla vasa recta were present at birth; norepinephrine and fluorescent fibers, however, were not found until 21 days. At this time nerves were found emerging in bundles from the arcuate connective tissue sheath and joining the vasa recta in the outer medulla. At subsequent ages the number of fibers in each bundle and the norepinephrine levels increased.

Background: Strongyloides stercoralis is a nematode that causes intestinal infection in vertebrate hosts, especially in humans and dogs. The species S. stercoralis is responsible for chronic and asymptomatic infections in adult dogs or serious infections in puppies and immunosuppressed animals. In Brazil, natural infection in dogs was demonstrated by coproparasitological and serological methods, however, there are no reports that address the clinicopathological characteristics of the infection in the canine species. Thus, this paper aims to describe the epidemiological, clinical and pathological aspects of S. stercoralis infection in a puppy in Northeastern Brazil.Case: A puppy female Chihuahua was referred to the Animal Pathology Laboratory of the Veterinary Hospital of the Federal University of Campina Grande for necropsy with a historic of severe respiratory symptoms and gastrointestinal changes that included sanguineous diarrhea and vomiting that evolved to death in 5 days. Grossly, there was a moderate amount of slightly reddish fluid in the thoracic cavity. The lungs remained expanded with a smooth, shiny, and diffusely reddish pleural surface interspersed with multifocal and blackened coalescent areas. Upon cutting, a moderate amount of slightly yellow foamy liquid flowed from the airways and trachea. In the duodenum, the mucosa was diffusely reddened. Histologically, there were multifocal to coalescent areas of moderate interalveolar accumulation of fibrin, edema and hemorrhage in the lung surrounded by an inflammatory infiltrate composed of foamy macrophages associated with numerous parasitic structures in longitudinal and transverse sections in the alveolar lumen and pleural surface. In the duodenum, we observed flattening with diffuse and moderate fusion of the villi and multifocal areas of mucosal erosion. The crypts were moderately dilated, covered by attenuated epithelium, with numerous longitudinal and transversal sections of adult nematode parasites, larvae and eggs associated with inflammatory lymphplasmocytic infiltrate in the lamina propria. The morphological characteristics were compatible with the nematode S. stercoralis.Discussion: The diagnosis of strongyloidiasis was performed by means of microscopic lesions associated with parasitic structures morphologically compatible with the nematode S. stercoralis. This species is responsible for parasitism especially in humans, dogs, and cats. Parasites are the only ones that have a life cycle that involve free living form and parasitic. In this case, it was not possible to determine the primary portal of entry for the infection, but most infections commonly occur through the penetration of the larvae into the skin or mucous membranes, where they migrate via the haematogenous to the lung, then they are swallowed up to the intestine. Occasionally, there is autoinfection by larvae that enter the intestinal mucosa or perianal region and the contamination of neonates and puppies through the ingestion of milk. The clinical signs evidenced in this case, revealed the committed respiratory and gastrointestinal, possibly may be related to the migration of the larvae in the lungs and the destruction of the intestinal epithelium caused by the high number of parasites, respectively. It is concluded that strongyloidiasis is an uncommon infectious disease in puppies in Brazil, capable of causing severe respiratory and gastrointestinal changes that result in the death of animals with a high parasitic load and should be included in the differential diagnosis of diseases that affect the respiratory system and gastrointestinal tract of dogs.Keywords: dog disease, parasitic infection, nematode, Strongyloides stercoralis.

Simple SummaryCats and dogs can form friendly relationships and conflict between them can harm their welfare. This study aimed to investigate factors related to ‘only desirable’ puppy behaviour (defined as being uninterested, ignored the cat or interacted in a calm way) towards existing household cats following introduction. Owners’ perceptions of the emerging cat-dog relationships were also explored. Quantitative and qualitative analyses were used to examine survey data collected as part of an ongoing study of dog health and behaviour. Of 4678 puppies, 26.7% lived with at least one cat. At the time of survey completion, 1211 puppies had been introduced to the household cat. The most common behaviours shown towards cats by puppies were: playing (58.9%), being overexuberant or over-excited (56.6%) and chasing (48.6%). Just 7.3% of puppies showed ‘only desirable’ behaviours. Puppies were more likely to show ‘only desirable’ behaviours when introduced before 12 weeks of age, gradually, and when they lived in a household with other dogs(s). Two styles of introductions were identified—owner-led and pet-led. Owners’ expectations of the cat-dog relationship differed depending on the style of introduction. Early, gradual, owner-led introductions of puppies to household cats can help them form a friendly relationship.Although cats and dogs can live amicably, inter-species conflict can result in poor welfare. Species introduction can impact the development of the cat-dog relationship. This study aimed to identify factors associated with owner reported ‘only desirable’ puppy behaviour (defined as the puppy being uninterested, ignored the cat and/or interacted in a calm way) following introduction to existing household cats, and to explore perceptions of the emerging cat-dog relationship. Owner-reported data collected as part of a longitudinal study of canine health and behaviour were used. Of 4678 puppies, 26.7% lived with at least one cat. Of the 1211 puppies who had been introduced to the household cat at the time of survey completion, playing (58.9%), being overexuberant or over-excited (56.6%), and chasing (48.6%) were the most common behaviours displayed towards cats. ‘Only desirable’ behaviours were shown by 7.3% of puppies. Multivariable logistic regression showed early (puppies aged <12 weeks), gradual introductions and living in a multi-dog household increased the odds of ‘only desirable’ behaviours. Qualitative analysis revealed two styles of introductions—owner-led and pet-led. Owners who led introductions anticipated amicable relationships between pets, whilst owners who let pets introduce themselves did not. Early, gradual, owner-led introductions of puppies to household cats should be encouraged.

Veterinary RecordVolume 162, Issue 18 p. 566-566 News & Report Rabies confirmed in a puppy in a UK quarantine facility First published: 03 May 2008 https://doi.org/10.1136/vr.162.18.566Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume162, Issue18May 2008Pages 566-566 RelatedInformation

SummaryA four month old Dalmatian puppy affected by congenital luxation of the radial head was very lame on the right front limb and was not weight bearing after little exercise. The radiological examination revealed humero-radial articular incongruity, excessive humeral trochlea development, trochlear notch deformation, and medial deviation of the olecranon. The surgery performed was derived from a modification of a human orthopaedic procedure, the Bell-Tawse technique. It was intended to increase the articular contact surface between the humerus and radius, with ostectomy, rotation, and osteosynthesis of the radius; to treat the luxation, by reduction and elbow annular ligament reconstruction; to prevent its recurrence, by means of a Kirschner pin inserted through the lateral humeral epicondyle to the radial head. Over six months the patient completely recovered.A congenital luxation of the radial head in a puppy was treated successfully employing a technique reported in human orthopaedics.