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PEMBUATAN SABUN PADAT EKSTRAK DAUN SUNGKAI (Peronema canescens Jack) SEBAGAI ANTIBAKTERI TERHADAP Staphylococcus aureus

Soap is a mixture of sodium compounds with fatty acids that are used as body cleaning agents, in solid form, foam, or without additives. Solid soaps on the market have the color, shape, aroma and additives needed by the skin as well as active ingredients that are able to reduce pathogenic microorganisms on the skin. Antibacterial active ingredients against Staphylococcus aureus can be obtained from sungkai leaf extract (Peronema canescens Jack) because it contains chemical compounds such as alkaloids, steroids, terpenoids, flavonoids, tannins and saponins. This study aims to determine the physical properties of solid soap of sungkai leaf extract in accordance with the quality standards of SNI 3532: 2016 and determine the antibacterial activity of solid soap of sungkai leaf extract against Staphylococcus aureus. Sungkai leaf extract is added with volume variations, namely 0 mL, 5 mL 10 mL, 15 mL, and 20 mL. The resulting solid soap is physically tested and antibacterial tests against Staphylococcus aureus. The results showed that solid soap of sungkai leaf extract has physical properties in accordance with the quality standards of SNI 3532-2016 and can inhibit the growth of Staphylococcus aureus bacteria. The best results were obtained at the addition of 10 mL of sungkai leaf extract. The soap has a dense texture, the aroma of sungkai leaf extract is not too pungent, pH 9.8, foam stability is 87.80%, moisture content is 3.54% and the diameter of the inhibitory zone against Staphylococcus aureus bacteria is 10 mm

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PENGARUH JENIS PELARUT DAN WAKTU EKSTRAKSI DENGAN METODE SOXHLETASI PADA PENGAMBILAN MINYAK KEMIRI (Aleurites moluccanus)

The candlenut plant is a plant that is used as a spice plant that produces oil with various benefits used in everyday life. The various benefits that exist in hazelnut oil make hazelnut oil popular with consumers in meeting their daily needs. This causes an increase in demand for hazelnut oil because the need is also increasing every year. Therefore, it is necessary to have an appropriate extraction method so that it can produce good quality hazelnut oil and maximum results. This research aims to determine the effect of the type of solvent and the most effective extraction time on the extraction of hazelnut oil using the soxhletation method. This research method is an experiment by varying the type of solvent, namely n-hexane, ethyl acetate and ethanol, as well as time variations, namely 60, 90 and 120 minutes with the soxhletation process. The tests in this study were the yield test, density test and water content test. In this study, it was shown that the best solvent for extraction of hazelnut oil was n-hexane because it could produce 18.64% yield with an extraction time of 120 minutes and had a clear yellow color with a density value of 0.926 g/mL in accordance with the hazelnut oil criteria determined by SNI . Extraction time has a major influence on the yield obtained. The longer the extraction time, the more randemen produced. In this study the best time for extraction was 120 minutes.

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UJI KUALITAS PADA SEDIAAN BABY HAIR LOTION DENGAN MENGGUNAKAN MINYAK ATSIRI BIJI KETUMBAR

Baby hair lotion is a baby cosmetic preparation that has a function to make hair strong and thick. There are already many baby skin and hair care products sold in the market. Baby's skin is at high risk of skin damage due to allergies, extravasation, and infection because the skin is very delicate. Emollients or preparations that soften the skin must be free of fragrances, dyes or preservatives. Among specifications, a product must consist of at least 95% organic ingredients to be called "organic." For this reason, it is important to know what ingredients are contained in the products used on baby's skin. This study aims to determine the effect of variations in the concentration of Almond oil, Aloe vera, and aquades on the final results of lotion preparations, and to determine the feasibility of lotion preparations in each variation carried out. Tests carried out on Baby Hair Lotion preparations are pH tests. Spreadability test, stickiness test, organoleptik test, and homogeneity. The variables used are independent variables, namely Almond oil content (36%, 30%, 25%, 15%, 12%), Aloe vera content (22%; 21.75%; 25%; 15%; 10.05%) , levels of Aquades (38.45%; 44.7%; 46.45%; 66.45%; 74.4%), for the dependent variable, namely levels of Cetearyl Alcohol (1%), Coriander seed oil (0.05% ), Lexgard Natural (0.5%), Plantasen (2%), while for the dependent variable the heating temperature is 60 -70oC.

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IDENTIFIKASI SENYAWA METABOLIT SEKUNDER DAN UJI TOKSISITAS HASIL FRAKSINASI EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus)

East Kalimantan, especially the cities of Tana Paser, is one of the producers of dragon fruit, especially red dragon fruit (Hylocereus polyrhizus). The amount of consumer interest in red dragon fruit results in a large amount of dragon fruit peel waste that is not utilized. Several studies have shown that red dragon fruit skin extract has toxic properties that can be applied to cancer cells. So in this study, the extraction and fractionation process was carried out which was then continued with phytochemical tests and BSLT tests with the aim of knowing secondary metabolites in the aqueous extract fraction, ethyl acetate extract fraction and n-hexane extract fraction with phytochemical test methods and to determine the toxicity of the fraction. aqueous extract, ethyl acetate extract fraction and n-hexane extract fraction were carried out using the BSLT test method. The results of the phytochemical test showed that the aqueous fraction extract of dragon fruit peel contained alkaloids, phenolics and saponins. The extract of the ethyl acetate fraction of dragon fruit peel contains phenolics and flavonoids. Fralsi n-hexane dragon fruit peel \contains triterpenoids. The results of the BSLT test showed that the LC50 value of the aqueous fraction extract was 451.855 ppm, the ethyl acetate fraction extract was 374.024 ppm, and the n-hexane fraction extract was 312.176 ppm which overall was classified as moderately toxic. The highest toxicity effectiveness was shown in the n-hexane fraction extract with triterpenoid secondary metabolite compounds.

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