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Fine Motor Activities in Elementary School Children: A Replication Study.

The educational landscape is continually changing in response to legislation and the adoption of new standards, such as the Common Core. Currently, little is known about how these changes have influenced the school day. To examine the motor and technology requirements of kindergarten, second-, and fourth-grade general education classrooms. For 6 full school days, we made unobtrusive observations of and took notes that described classroom activities throughout the day. Data were coded by a committee, allocating each minute of the day into 1 of 10 activity categories. Kindergarten, second-, and fourth-grade classrooms. Three general education classrooms with approximately 20 students in each class. Students spent between 37.1% and 60.2% of the school day performing fine motor activities, with handwriting accounting for 3.4%-18.0% of the day. Time spent using technology was relatively sparse in kindergarten (4.8%) and second grade (3.1%) compared with fourth grade (14.3%). Transitions between activities (18.9%-23.4% of time spent) exceeded time spent handwriting. This article provides an updated estimate of motor demands throughout the school day. Estimates of fine motor activities were consistent with previous research, but the focus on handwriting appears to have substantially diminished. Within the context of their own school, occupational therapists may find transitions to be a good opportunity for providing services within the classroom. In addition, handwriting practice outside of school may be more necessary in the current educational climate than in previous years.

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Student-Centered Microbioassay Laboratory Activity Utilizing Bioluminescent Bacteria.

Student-centered teaching allows students to be actively engaged in hands-on, minds-on activities that emphasize creativity and collaboration, enabling them to ask questions and design their own investigations to real-world problems. One such problem is water contamination, which causes human health and environmental issues. However, chemical water quality testing for pollutants can be timely and expensive. In addition to chemical testing, researchers have developed assays using unicellular organisms to determine which pollutants are present and in what concentrations. In this three-hour laboratory activity, high school students and undergraduate biology or microbiology students work in pairs to help a fictional company develop a water quality microbioassay. Students design their own laboratory protocols to test the reaction of a bioluminescent bacterial species (i.e., Photobacterium phosphoreum or Aliivibrio fischeri ) to exposure of common aquatic pollutants such as fertilizer, household cleaners, and motor oil. During this laboratory activity, students apply previously learned components of experimental design, including positive and negative controls, constants, and experimental groups. In addition, students gain experience writing a scientific explanation for a recommendation regarding the bioluminescent bacteria's suitability in a bioassay. Pre- and post-evaluation data revealed that students were successful in achieving the activity's objectives as well as in designing their investigations and writing their protocols using scaffolds within the lesson.

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A high‐fat diet impairs alternative splicing of the troponin T pre‐mRNA in skeletal muscle

Obesity leads to deficits in skeletal muscle function that are accompanied by reduced physical activity and energy expenditure. The basis of such deficits may originate from within the contractile apparatus, but little is known about how obesity might interfere with body weight‐induced changes in skeletal muscle composition. We recently showed that in obese Zucker rats, body weight‐appropriate alternative splicing of troponin T (TnnT3) pre‐mRNA is impaired, representative of a mismatch between body weight and skeletal muscle molecular composition. However, the generality of these finding to other models of obesity is unknown. In the present study, alternative splicing of the TnnT3 pre‐mRNA was observed within 1 wk of feeding a HFD to Sprague‐Dawley rats, even though no significant change in either body weight or composition was apparent. Moreover, changes in alternative splicing were dose‐dependent, with a greater effect observed in animals fed a diet containing 60 compared to 30 or 45 kcal% from fat. These findings represent the first evidence of nutrient‐induced regulation of alternative splicing in mammals, and suggest that early‐onset disruptions of body weight homeostasis in response to HFD may play an important role in the development of obesity. (support: NIH DK15658 (LSJ), Pennsylvania Department of Health (SRK), APS Postdoctoral Fellowship (RJS), and an APS 2011 Frontiers in Physiology Award (EAC))

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Effects of Computer System and Vowel Loading on Measures of Nasalance

The purpose of this study was to determine similarities and differences in nasalance scores observed with different computerized nasalance systems in the context of vowel-loaded sentences. Methodology Subjects were 46 Caucasian adults with no perceived hyper- or hyponasality. Nasalance scores were obtained using the Nasometer 6200 (Kay Elemetrics Corp.), the Nasometer II 6400 (Kay Elemetrics Corp.), and the NasalView (Tiger DRS, Inc.) for sentences loaded with mixed, high front, high back, low front, or low back vowels. Measures of nasalance obtained with the NasalView were significantly higher than those obtained with the Nasometer 6200, and the measures of nasalance obtained with the Nasometer 6200 were significantly higher than those obtained with the Nasometer II 6400. However, similar effects of vowel loading on measures of nasalance were observed, regardless of system. For all systems, the high front vowel sentence tended to result in higher measures of nasalance than did the high back, low front, and low back vowel sentences--the mixed vowel sentence tended to have a higher degree of nasalance than did any of the other sentences. Although nasalance data computed using different systems are not readily comparable, all three systems that were evaluated produced similar effects of vowel loading on nasalance. Increased nasalance for high front versus low back vowels may be due to factors such as increased oral impedance, reduced radiated oral sound pressure, possible increases in airflow via the nasal cavity, and increased transpalatal nasalance.

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