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Perceptions of Teenage Psychological Disorder

The twenty-first century brought unprecedented rates of teenage psychological disorder (PD), with conditions such as depression, anxiety, and schizophrenia reaching all-time highs. Young adolescents, despite having been recognized as a psychologically vulnerable demographic, are constantly excluded in their own mental health evaluations, and teachers in the American education system play a pivotal role in addressing this gap. Thus, in this paper, I specifically explore how high school students and teachers perceive teenage PD by examining their opinions on literary portrayals of mentally ill adolescents. This article thoroughly investigates this inquiry by utilizing quantitative, open-ended survey research followed by a thematic and comparative analysis. A total of 43 students and 24 teachers participated in the study, and I identified five recurring themes throughout their responses: the validity of teenagers’ struggles, PD’s relation to teenagers’ school life, PD’s relation to teenagers’ social life, trust in professional treatment, and the potential of recovery. My findings demonstrated that although both groups showed a mutual concern for the mental welfare of teenagers, there were stark differences between students’ and teachers’ perceptions of teenage PD. These results present a fundamental ideological dichotomy that must be bridged in order to help adolescents benefit from their schools, and an implementation of comprehensive mental health and social and emotional well-being (SEWB) training for all teachers may be the first step to achieving this goal.

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Correlating Anxiety and Risk Perceptions of Future Academic Prospects Among High-Achieving Students

The twenty-first century is redefining the boundaries of adolescent mental health with its “epidemic of anxiety.” As a psychologically vulnerable demographic, academically intensive high school students are as unrivaled in their anxiety levels as they are in their ambition, which inflates their fear factors and undermines their personal values as well. In this paper, I expand on this subject by specifically exploring high-achieving students’ risk perceptions of their future academic prospects and how they correlate with symptoms of generalized anxiety disorder (GAD). This study dives into the inquiry by utilizing quantitative survey research followed by a mixed cross-examination analysis. A total of 47 Advanced Placement high schoolers responded to the survey, and, based on the final numerical values assigned to their anxiety and risk perception levels, I calculated several correlation coefficients to interpret the results. My findings demonstrated that there was a strong positive correlation between anxiety and risk perceptions of academic prospects among high-achieving students. Despite their superlative academic statistics, results showed that many of the participants not only had high anxiety levels but also perceived a substantial amount of risk for their future success. This target population comprises only a fraction of teenagers who experience such symptoms, but this study presents how they uphold negative trends in anxiety-related disorders that require more attention and research in the field of psychology as a whole.

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Recognition of bacterial promoter ‐10 region by σ subunit of RNA polymerase

RNA polymerase (RNAP), a bacterial cell regulation target, binds promoters, then opens DNA near the transcription start site. The crucial step in DNA promoter melting is −10 element (consensus sequence T−12A−11T−10A−9A−8T−7) recognition by the RNAP sigma (σ) subunit. X‐ray crystallography reveals details of ‐10 element recognition by σ. Single stranded (ss) DNA with the TATAAT sequence is draped across a σ conserved surface, with a 90° turn between the −11 and −10. Specific interactions occur with the most conserved bases: T‐12, A‐11, and T‐7, especially A‐11 and T‐7, which are flipped out of ss DNA and buried in σ pockets. A hydrophobic pocket tightly fits A‐11 between σ R246 and Y253. A‐11 hydrogen bonds with σ K241, F242 and E243. T‐7 fits in a large hydrophilic σ pocket with three ordered waters. T‐7 hydrogen bonds with L209 and N206 and has water‐mediated interactions with several σ residues. Less important central bases, ‐10T, ‐9A and ‐8A, point away from σ and make few or no base‐specific contacts with the protein. The structure reveals insights into initiation of transcription bubble formation and suggests interesting ideas for rational antimicrobial design. The Leonia High School SMART (Students Modeling a Research Topic) Team partnered with a researcher to create a physical model of σ interacting with the DNA ‐10 element using 3D printing technology. Supported by a grant from HHMI Pre‐College Program.

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