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Achieving superior strength-ductility combination in the heterogeneous microstructured Ti64 alloy via multi-eutectoid elements alloying with CoCrFeNiMn during laser powder bed fusion

ABSTRACT The formation of coarse needle-shaped α′-Ti within columnar β-Ti grains in additively manufactured titanium alloy components is nearly unavoidable, and it can lead to unforeseeable service failures. This study employs a multi-component eutectoid alloying strategy, integrating CoCrFeNiMn high-entropy alloy particles within Ti64 alloy. By varying laser parameters, the resulting microstructure transitions from β-dominated to a metastable β + nanoscale α′ microstructure. The coarse needle-shaped α′-Ti and columnar β-Ti grains are significantly refined. Concurrently, the multi-component eutectoid alloying strategy successfully suppresses the formation of detrimental intermetallic compounds by promoting the uniform distribution and solubility of the alloying elements. The Ti64-(4.5%) CoCrFeNiMn alloy demonstrates exceptional mechanical properties, including high tensile strength (1333.8 MPa), uniform elongation (9.3%), and a work-hardening capacity (>390.0 MPa). These are attributed to the continuous variation of Co, Cr, Fe, Ni, and Mn concentrations within the ultrafine α′ and metastable β-phase regions, providing a progressive transformation-induced plasticity effect.

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Charging station planning scheme by making efficient use of soft computing techniques for low carbon transition

For sustainable energy management, soft computing can play an important role in developing a charging station planning for low carbon transition to address the challenges faced by electric vehicle (EV) infrastructure system. This article proposes a planning scheme for charging stations of electronic vehicles for low carbon transition using soft computing-based computational techniques in the transportation sector. The existing charging stations have many flaws which are acting as hindrance in the development and acceptance of electronic vehicles by consumers. These flaws include the unreasonable layout of charging terminals, difficulty in charging, consumption of time in charging, and consumer convenience. This paper proposes a novel planning model for charging electronic vehicles as an innovative solution for electronic vehicles for low carbon transition. The protection of the environment is important in this current era and switching to electronic vehicles is a mandate for low-carbon transitions in the transportation sector. The proposed method begins with the collection of data from diverse sites of charging stations using the existing charging infrastructure, and this data also analyzed for ascertaining the energy consumption patterns, availability of renewable energy options, flow of traffic, and consumer preferences. The proposed method aims to augment the deployment of convenient charging infrastructure to promote consumers to switch to electronic vehicles from fuel-based vehicles and to promote renewable energy solutions for electric vehicles (EVs) at economic costs. The location and capacity of charging terminals is also optimized with the aid of hybrid algorithm based on catfish and PSO algorithms in this proposed research work. The effectiveness of the proposed soft computing-based hybrid algorithm is tested by using standard statistical methods and respective results are presented in the result section of this article. The proposed research has practical implications in a real-world scenario where consumers can be promoted to use electric vehicles by optimizing the capacity and availability of the charging station infrastructure which can eventually reduce the carbon footprints from this world.

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Fractionated plasma separation and adsorption integrated with continuous veno-venous hemofiltration in patients with acute bipyridine herbicide poisoning

Objective To evaluate the clinical efficacy and safety of fractionated plasma separation and adsorption combined with continuous veno-venous hemofiltration (FPSA-CVVH) treatment in patients with acute bipyridine herbicide poisoning. Methods A retrospective analysis of 18 patients with acute bipyridine herbicide poisoning was conducted, of which 9 patients were poisoned by diquat and 9 patients by paraquat. All patients underwent FPSA-CVVH treatment. The serum cytokine levels in pesticide-poisoned patients were assessed. The efficacy of FPSA-CVVH in eliminating cytokines, the 90-d survival rate of poisoned patients, and adverse reactions to the treatment were observed. Results Fourteen patients (77.8%) had acute kidney injuries and 10 (55.6%) had acute liver injuries. The serum cytokine levels of high mobility group protein B-1 (HMGB-1), interleukin-6 (IL-6), IL-8, interferon-inducible protein-10 (IP-10), monocyte chemotactic protein-1 (MCP-1), and macrophage inflammatory protein-1β (MIP-1β) were significantly elevated. A total of 41 FPSA-CVVH treatment sessions were administered. After a single 8-h FPSA-CVVH treatment, the decreases in HMGB-1, IL-6, IL-8, IP-10, MCP-1, and MIP-1β were 66.0%, 63.5%, 73.3%, 63.7%, 53.9%, and 54.1%, respectively. During FPSA-CVVH treatment, one patient required a filter change due to coagulation in the plasma component separator, and one experienced a bleeding adverse reaction. The 90-d patient survival rate was 50%, with 4 patients with diquat poisoning and 5 patients with paraquat poisoning, and both liver and kidney functions were restored to normal. Conclusion Cytokine storms may play a significant role in the progression of multiorgan dysfunction in patients with acute bipyridine herbicide poisoning. FPSA-CVVH can effectively reduce cytokine levels, increase the survival rate of patients with acute bipyridine herbicide poisoning, and decrease the incidence of adverse events.

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The representation of medical risks and incentives concerning egg donation: an analysis of the websites of fertility clinics of Belgium, Spain and the UK

Considering the growing demand for egg donation (ED) and the scarcity of women coming forward as donors to meet this demand, scholars have expressed concerns that clinics may (initially) misrepresent risks to recruit more donors. Additionally, (non-)monetary incentives might be used to try to influence potential donors, which may pressure these women or cause them to dismiss their concerns. Since the internet is often the first source of information and first impressions influence individuals' choices, we examined the websites of fertility clinics to explore how they present medical risks, incentives and emotional appeals. Content Analysis and Frame Analysis were used to analyze a sample of Belgian, Spanish and UK clinic websites. The data show that the websites mainly focus on extreme and dangerous risks and side effects (e.g. severe OHSS) even though it is highly relevant for donors to be informed about less severe but more frequently occurring risks and side effects (e.g. bloating), since those influence donors' daily functioning. The altruistic narrative of ED in Europe was dominant in the data, although some (hidden) financial incentives were found on Spanish and UK websites. Nonetheless, all information about financial incentives still were presented subtly or in combination with altruistic incentives.

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