ZrOCl 2·8H 2O mediated microwave induced [3+2] cycloaddition of azomethine ylides—a facile one-pot synthesis of novel dispiroheterocycles

Abstract

An efficient microwave-assisted, ZrOCl 2·8H 2O mediated, synthesis of novel dispiro-oxindolopyrrolidines and -pyrrolizidines was accomplished through [3+2] cycloaddition reaction of azomethine ylides derived from acenaphthenequinone and sarcosine/ l-proline with ( E)-2-oxoindolino-3-ylidene acetophenones in good yields.