Zootechnical and veterinary methods of high-producing dairy cows treatment

Abstract

The article represents the results of research into the development of a remedy for treating puerperal mastitis and endometritis in high-producing cows. The work was carried out at The Department of Obstetrics, Surgery, and Physiology of Domestic Animals in Don State Agrarian University. The research involved a complex pharmaceutical composition used as a dosage form and containing yotoin as the active substance, excipients (retinol, dexamethasone, propolis), and vehicle (liquid paraffin). When getting into an affected cavity, the remedy is completely absorbed and therapeutically acts on affected tissues and organs both generally and locally. The effect is adjusted depending on the disease severity. All studied compositions have a high therapeutic effect. However, they differ in the time needed for the improvement in wellbeing to appear and the length of therapeutic treatment. We chose composition no. 2 as the optimal for further clinical trials. When using the tested remedy, the improvement in the general and local well-being of an animal appeared on the fifth day since the beginning of treatment. The whole therapeutic treatment took 10 days. The tested remedy showed a 100% therapeutic effectiveness.