Zoonotic Antimicrobial Resistance as a Result of Iatrogenic Disease in Companion Animals - Case Study Reports

Meade Elaine,Garvey Mary,Slattery Mark Anthony

doi:10.23937/2474-3658/1510073

Abstract

Iatrogenic disease represents an ongoing issue for veterinarians where animals manifest with secondary conditions as a result of medical treatment. Similarly, zoonotic disease and specifically resistant zoonotic pathogens represent an ongoing issue for public health safety. As an increasing number of zoonotic microbial species are being recognised as emerging and re-emerging diseases in humans, the issues relating to their antimicrobial resistance becomes more evident. This study reports on two cases of iatrogenic invasive microbial disease in companion animals following previous treatment for dermal conditions.

Highlights

Iatrogenic diseases are secondary diseases which result from the diagnostic and therapeutic treatment of a patient presenting with a primary disease state
This study reports on two cases of iatrogenic invasive microbial disease in companion animals following previous treatment for dermal conditions
Study reports on 2 canine patients representing with dermal symptoms of infection, cases were assessed via veterinary therapeutics and microbial diagnostics to determine the causative agents of the disease symptoms

Summary

Introduction

Iatrogenic diseases are secondary diseases which result from the diagnostic and therapeutic treatment of a patient presenting with a primary disease state. The treatment of companion animals for mycotic or bacterial infections often requires the prescribing of non-antimicrobial therapeutics such as steroids (prednisolone or trilostane) to elevate symptoms such as pruritus and subsequent alopecia. Prolonged treatment with these immune suppressors may lead to secondary disease of the animal such has iatrogenic Addison’s disease or hyperadrenocorticism [2]. Study reports on 2 canine patients representing with dermal symptoms of infection, cases were assessed via veterinary therapeutics and microbial diagnostics to determine the causative agents of the disease symptoms. Diagnosis of iatrogenic dermal pyoderma and subsequent invasive AMR meningitis due to prolonged treatment of dermal hypersensitivity issues with glucocorticoid steroids having immunosuppression activity

Findings

Discussion

Conclusion