Abstract

Background: Zollinger-Ellison syndrome is the consequence of excessive and autonomous secretion of gastrin from gastrinoma cells. The disease is exceptionally rare and characterized by severe and treatment-resistant peptic disease that can become life-threatening for a patient. In most cases, gastrinoma is malignant. A case of 44-year patient is presented. Conclusions: We present clinical manifestations, laboratory diagnostic tests, modalities of tumor localization and forms of treatment that are clinically relevant in a patient, suspected of having this rare disease. Pathohistologically, our patient’s tumor was identified as a carcinoid with minor gastrinoma fraction.

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