Abstract

Cancer Therapy In article number 2104037, Xiang Li, Zhen Gu, Xiujun Cai, and co-workers report that the generated H2S and released zinc ions from ZnS@BSA nanoclusters promote accumulation of reactive oxygen species to activate cGAS/STING signals in tumor cells. ZnS@BSA nanoclusters are further demonstrated to facilitate antitumor immunotherapy by immune cell infiltration, showing potential for clinical translation.

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