Zn(ferulate)-LSH Systems as Multifunctional Filters.

Gustavo Pereira Saito,Marco Aurélio Cebim,Marian Rosaly Davolos,Ana Carolina Lanfredi Matsumoto,Iguatemy Lourenço Brunetti,Renata Pires Assis

doi:10.3390/molecules26082349

Gustavo Pereira Saito, Marco Aurélio Cebim + Show 4 more

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https://doi.org/10.3390/molecules26082349

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Abstract

Excessive UV solar radiation exposure causes human health risks; therefore, the study of multifunctional filters is important to skin UV protective ability and also to other beneficial activities to the human organism, such as reduction of reactive oxygen species (ROS) responsible for cellular damages. Potential multifunctional filters were obtained by intercalating of ferulate anions into layered simple metal hydroxides (LSH) through anion exchange and precipitation at constant pH methods. Ultrasound treatment was used in order to investigate the structural changes in LSH-ferulate materials. Structural and spectroscopic analyses show the formation of layered materials composed by a mixture of LSH intercalated with ferulate anions, where carboxylate groups of ferulate species interact with LSH layers. UV-VIS absorption spectra and in vitro SPF measurements indicate that LSH-ferulate systems have UV shielding capacity, mainly UVB protection. The results of reactive species assays show the ability of layered compounds in capture DPPH•, ABTS•+, ROO•, and HOCl/OCl− reactive species. LSH-ferulate materials exhibit antioxidant activity and singular optical properties that enable their use as multifunctional filters.

Highlights

Solar ultraviolet radiation (UV) is important for living organisms [1], especially humans [2], because it induces photochemical reactions responsible for the development and survival of these living species [3]
LSHferulate material synthesized by the anion exchange method was named Zn-fel-layered simple metal hydroxides (LSH)/A and LSH-ferulate materials prepared by the precipitation method with Zn2+ /C10 H9 O4 − = 3, 4 and 5 molar ratio were designated Zn-fel(3)-LSH, Zn-fel(4)-LSH, and Zn-fel(5)-LSH, respectively
LSH-ferulate materials were successfully synthesized by the anion exchange method and precipitation method at constant pH varying Zn2+ /fel− molar ratio and ultrasound treatment time

Summary

Introduction

Solar ultraviolet radiation (UV) is important for living organisms [1], especially humans [2], because it induces photochemical reactions responsible for the development and survival of these living species [3]. Excessive UV radiation exposure causes damaging biological effects in the human organism [1,2,3,4,5,6] such as sunburns, premature aging, irregular skin pigmentation, and skin cancer. The chemical compounds that absorb and/or scatter UV radiation without changes in their physicochemical properties or do not decompose are denominated inorganic or organic filters [8]. These compounds are optical filters [9,10], which attenuate UV light and can transmit other radiations that compose solar spectrum. The UV shielding capacity of inorganic or organic filters makes them active constituents of the photoprotective products, e.g., sunscreens [11]

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