Abstract

Purpose: Mesenchymal stem cells (MSCs) possess the ability of multi-differentiation and can be used as a suitable source of seed cells for cartilage tissue engineering. The phenotype at the later stage of chondrogenic differentiation also mimics the process of cartilage degeneration. Thus, this study aims to investigate the effect of circRNA ZKSCAN1 from MSC-derived on in chondrogenesis and cartilage degeneration.

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