Zirconium triflate: An efficient catalyst for the synthesis of quinolines and quinoxalines

Abstract

An environmentally friendly method is described for the preparation of substituted quinoline and quinoxaline derivatives using Zr(OTf)4 as an efficient catalyst. The method is based on using 1,3-diketones, ketones and 2-aminoaryl ketones under solvent-free conditions and also on using 1,2-diketone, 1,2-diamine in EtOH/H2O at room temperature for quinloine and quinoxaline synthesis, respectively. The advantages in using this method, include its environmental friendliness, simple operating process and good yields.