Abstract
AbstractWe report the rational design of coordination‐driven self‐assembly metal–organic nanostructures for multifunctional nanotheranostics. Zinc(II) coordination‐based nano‐formulations capable of loading indocyanine green (ICG) and therapeutic genes were prepared to achieve a fluorescence/photoacoustic imaging‐guided combination photo/gene therapy strategy. We showed the enhanced theranostic capability of zinc(II)‐dipicolylamine‐assisted assembly of ICG, as well as simultaneous targeted gene delivery in an experimental mouse model of cancer. Such a co‐assembly strategy provides a facile way to achieve combined therapeutic functions for personalized nanomedicine.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
