Zinc-based particle with ionic liquid as a hybrid filler for dental adhesive resin

Abstract

ObjectivesThe aim of this study was to evaluate the effect of a zinc-based particle with ionic liquid as filler for an experimental adhesive resin. MethodsThe ionic liquid 1-n-butyl-3-methylimidazolium chloride (BMI.Cl) and zinc chloride (ZnCl2) were used to synthesize 1-n-butyl-3-methylimidazolium trichlorozincate (BMI.ZnCl3), which was hydrolyzed under basic conditions to produce the simonkolleite (SKT) particles. SKT was analyzed by scanning electron microscopy and transmission electron microscopy. An experimental adhesive resin was formulated and SKT was incorporated at 1, 2.5, or 5 wt.% in the adhesive. One group without SKT was a control group. The antibacterial activity against Streptococcus mutans, cytotoxicity, degree of conversion (DC), ultimate tensile strength (UTS), softening in solvent, and microtensile bond strength (μ-TBS) were investigated. ResultsSKT prepared from the ionic liquid BMI.ZnCl3 presented a hexagonal shape in the micrometer scale. SKT addition provided antibacterial activity against biofilm formation of S.mutans and planktonic bacteria (p < 0.05). There were no differences in pulp cells’ viability (p > 0.05). The DC ranged from 62.18 (±0.83)% for control group to 64.44 (±1.55)% for 2.5 wt.% (p > 0.05). There was no statistically significant difference among groups for UTS (p > 0.05), softening in solvent (p > 0.05), and 24 h or 6 months μ-TBS (p > 0.05). ConclusionsThe physicochemical properties of adhesives were not affected by SKT incorporation, and the filler provided antibacterial activity against S. mutans without changes in the pulp cells' viability. This hybrid zinc-based particle with ionic liquid coating may be a promising filler to improve dental restorations. Clinical relevanceA filler based on a zinc-derived material coated with ionic liquid was synthesized and added in dental adhesives, showing antibacterial activity and maintaining the other properties analyzed. SKT may be a promising filler to decrease the biofilm formation around resin-based restorative materials.