Abstract
The importance of zinc (Zn) for cardiovascular health continuously gains recognition. As shown earlier, compromised Zn homeostasis and prolonged inflammation are common features in various cardiovascular diseases (CVDs). Similarly, Zn biochemistry alters several vascular processes, and Zn status is an important feature of cardiovascular health. Zn deficiency contributes to the development of CVDs; thus, Zn manipulations, including Zn supplementation, are beneficial for preventing and treating numerous cardiovascular (CV) disorders. Finally, additional long-term, well-designed studies, performed in various population groups, should be pursued to further clarify significant relationships between Zn and CVDs.
Highlights
Zinc (Zn) is one of the most essential micronutrients involved in numerous crucial biological functions, i.e., cell differentiation and proliferation, cellular transport, DNA synthesis, endocrine, immune, and central nervous system functioning, reproduction, gene expression, and homeostasis [1]
Zn deficiency significantly affects the functioning of biological systems, creates dysfunctions in humoral and cell-mediated immunity, increases the vulnerability to infections—predisposing people to disturbances in gut microbiota activity, increases the incidence of bacterial, viral, and fungal infections, and leads to the progression of chronic and degenerative diseases, i.e., type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVDs), and cancers [3]
This study provides a concise and thorough overview of the relationship between Zn homeostasis and CVDs
Summary
The importance of zinc (Zn) for cardiovascular health continuously gains recognition. As shown earlier, compromised Zn homeostasis and prolonged inflammation are common features in various cardiovascular diseases (CVDs). Zn biochemistry alters several vascular processes, and Zn status is an important feature of cardiovascular health. Zn deficiency contributes to the development of CVDs; Zn manipulations, including Zn supplementation, are beneficial for preventing and treating numerous cardiovascular (CV) disorders. Additional long-term, well-designed studies, performed in various population groups, should be pursued to further clarify significant relationships between Zn and CVDs. Reviewed by: Wimal Pathmasiri, University of North Carolina at Chapel Hill, United States Robert Fred Clark, RTI International, United States. Specialty section: This article was submitted to Nutrigenomics, a section of the journal
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
